How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
-
1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
-
2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
-
3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
-
4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
-
5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
-
6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is LAZCLUZE?
LAZCLUZE (lazertinib) is an FDA-approved medicine that is used in combination with amivantamab as a first-line treatment for adults with non-small cell lung cancer (NSCLC) that carries specific EGFR gene mutations. The FDA first approved this medicine on August 19, 2024. This approval was based on extensive clinical data that showed that LAZCLUZE outperformed osimertinib (the previous standard of care).
LAZCLUZE belongs to a group of drugs known as kinase inhibitors. These drugs work by blocking the abnormal signals that help cancer cells grow and spread. LAZCLUZE comes in tablet form. The drug should be taken once daily with or without food.
What Is LAZCLUZE Used To Treat?
LAZCLUZE (lazertinib) is used in combination with amivantamab to treat patients with non-small cell lung cancer (NSCLC) that can not be removed surgically or has spread to other parts of the body (metastatic). The NSCLC must have one of the following mutations on the epidermal growth factor receptor (EGFR) gene:
- Exon 19 deletions
- Exon 21 L858R substitution
Before starting the treatment with LAZCLUZE, you must conduct an FDA-approved test to confirm that you have the above-mentioned mutations.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
-
Advanced software locates funding sources to match you with top-dollar foundation programs
-
One of our copay assistance specialists will assist with the application process
-
Automatic updates will be sent to you and your physician on the status of the funding
How Does LAZCLUZE Work?
There is a gene in your body called epidermal growth factor receptor (EGFR), which is responsible for cell growth and multiplication. Normally, these genes would turn on and off when needed to keep cell growth balanced.
But, in many cases of non-small cell lung cancer (NSCLC), changes (mutations) occur in the EGFR gene. These mutations cause the gene to stay switched on and continuously signal the cancer cells to grow. As a result, cells multiply uncontrollably and form tumors.
LAZCLUZE attaches to the abnormal EGFR receptors inside the cancer cells and blocks the abnormal growth signals. As a result, the growth of the cancer cells slows down.
LAZCLUZE is mainly used together with amivantamab. While LAZCLUZE blocks EGFR activity inside the cell, amivantamab targets EGFR and MET on the outside of the cell. If you take them together, they will attack the cancer through multiple pathways. This makes the treatment more effective.
LAZCLUZE Side Effects
Common side effects include:
- Rash
- Nail toxicity
- Swelling
- Fatigue
- Diarrhea
- Dry skin
- Pain in the bones, muscles, joints, or nerves
- Nausea
- Itching
Serious Side Effects
Serious side effects are rare but can happen. Here are some serious side effects:
Blood Clots: LAZCLUZE can cause blood clots in your legs or lungs, which can be fatal. To prevent this, your doctor will give you anticoagulation medicines for the first 4 months of your treatment.
Serious Allergic Reactions: You may experience allergic reactions while taking LAZCLUZE, which can be severe. Symptoms of serious allergic reactions include fever, increased heart rate, trouble breathing, hives, and swelling of your face, lips, and mouth.
Lung Problems: This medication can cause serious lung problems, which can be fatal. Symptoms include cough, trouble breathing, and fever. Contact your doctor right away if you experience these symptoms.
Skin Problems: You may experience severe skin problems while taking LAZCLUZE. Symptoms include itching, severe rash, skin redness, and dry skin. It is recommended that you limit your sun exposure during treatment and for 2 months after treatment. Protective clothing and sunscreen can help.
Please note that this is not a complete list of all possible side effects. Contact your doctor immediately if you experience any severe side effects.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
Get Started in Minutes
Fill out your information and one of our specialists will call you ASAP.
How Much Can You Save?
Complete this form to save up to 100%!
By submitting, you agree to AmeriPharma’s Terms of Use, Privacy Policy, and Notice of Privacy Practices