How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Granix?
Granix, also known by the name of its active drug “tbo-filgrastim,” is a prescription medication typically prescribed to treat and reduce the duration of severe neutropenia in patients undergoing chemotherapy or taking anticancer medications.
Granix belongs to the class of colony-stimulating factors (CSF), which are the type of glycoproteins that stimulate the production of WBCs, especially neutrophils (a type of white blood cells that are important in fighting bacterial infections).
The FDA first approved Granix on August 30, 2012, and it is currently available as an injection solution.
How Does Granix Work?
Granix works to stimulate the production of WBCs (neutrophils) and shorten the time patients have severe neutropenia during chemotherapy.
When a cancer patient undergoes chemotherapy, the anticancer medicines that fight cancer cells also kill the healthy white blood cells (WBCs), resulting in a low number of neutrophils in the blood. This increases a patient’s susceptibility to certain infections.
Working Mechanism of Granix (Tbo-Filgrastim)
The active component of Granix, “filgrastim,” works like a naturally produced colony-stimulating factor (CSF) in the body. Filgrastim signals the stem cells in the bone marrow to make more white blood cells (neutrophils). The newly produced neutrophils then migrate from the bone marrow into the blood circulation to fight infection.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
What Are the Available Dosage Forms and Strengths?
Granix is available as a single-use prefilled syringe with a strength of 300 mcg/0.5 ml and 480 mcg/0.8 ml.
Dosing Information
The recommended dose of Granix for adult and pediatric patients (1 month and older) is 5 mcg/kg once a day. The first dose is usually given within 24 hours after the chemotherapy dose.
You should not receive a Granix injection earlier than 24 hours before your next chemotherapy session.
How Is Granix Administered?
Granix is injected subcutaneously (under the skin of the abdomen, arms, upper hips, or buttocks) by the healthcare provider.
It is administered once a day until the neutrophil count returns to the normal range.
Granix Side Effects
Common side effects include:
- Thrombocytopenia (low platelet count)
- Dizziness or headache
- Fever
- Pain in the arms and legs
- Diarrhea
Serious side effects include:
- Serious allergic reactions (swelling, wheezing, rash all over the body, shortness of breath, fast heart rate, and swelling around eyes or mouth)
- Spleen rupture (spleen becomes enlarged and ruptures)
- Acute respiratory distress syndrome (symptoms include shortness of breath, fever, or trouble breathing)
- Sickle cell crisis
- Kidney injury
- Capillary leak syndrome (a condition in which fluid leaks from blood vessels into tissues)
- Leukocytosis (increased white blood cell count)
- Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML)
- Aortitis (inflammation in the aorta)
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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