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Immunotherapy FAQs

Immunotherapy

Who Qualifies for Immunotherapy?

  • Not everyone with cancer qualifies for immunotherapy. Eligibility depends on factors including cancer type, disease stage, specific tumor biomarkers, and overall health. 
  • The decision is typically made on a case-by-case basis by a patient’s oncology team.

Factors that Affect Immunotherapy Eligibility

A physician will typically evaluate:

  • Cancer type and stage — some immunotherapies are only approved for advanced or metastatic disease
  • Biomarker testing — labs may test for PD-L1 expression, microsatellite instability (MSI-H), mismatch repair deficiency (dMMR), or tumor mutational burden (TMB) to predict response
  • Prior treatments — some immunotherapy drugs are approved after chemotherapy has been tried; others are used as first-line treatment
  • Overall health and performance status — patients must be healthy enough to tolerate potential immune-related side effects
  • Autoimmune conditions — existing autoimmune diseases may increase the risk of side effects and could affect eligibility

    FDA-Approved Immunotherapy Cancer Treatment

    The FDA has approved immunotherapy treatments for cancers such as:

    • Bladder cancer, kidney cancer, liver cancer — multiple FDA-approved options available
    • Head and neck cancers — approved for recurrent or metastatic disease
    • Certain blood cancers (Hodgkin lymphoma, non-Hodgkin lymphoma, leukemia) — CAR-T cell therapy and checkpoint inhibitors may apply

    • Colorectal cancer with specific biomarkers (MSI-H or dMMR status)

    • Some solid tumors with high tumor mutational burden (TMB-H), regardless of cancer type

    Read more about cancer and immunotherapy cancer medications here:

    Is Immunotherapy Right For You?

    If your doctor has recommended immunotherapy or you'd like to learn whether immunotherapy may be an option for you, contact AmeriPharma Specialty Care to speak with a specialist today.

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