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Camcevi: What You Need To Know About This FDA-Approved Prostate Cancer Treatment

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Camcevi is an FDA-approved cancer medication. It is used to treat advanced prostate cancer in adult males. Learn about Camcevi’s mechanism of action, dosage, side effects, cost, and more.

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Important Camcevi Warnings

Worsening of Symptoms

Camcevi is a drug that may worsen prostate cancer symptoms or cause additional symptoms during the first few weeks of treatment. Your healthcare provider will watch you closely during this period.

Camcevi can also worsen bone pain and cause difficulty passing urine. In some people, this medication can cause spinal cord compression, which may result in paralysis. Seek emergency medical care if you experience:

  • Loss of sensation in the feet
  • Weakness in the foot, causing a limp
  • Trouble with hand or leg coordination
  • Pain and stiffness in the neck or back
  • Numbness, cramping, or weakness in the arms, hands, or legs
  • Burning pain that spreads to your arms, buttocks, or down into the legs

Low Blood Sugar and Diabetes

Camcevi can make you more likely to develop diabetes. Your healthcare provider will check your blood sugar levels periodically during treatment.

Diseases of the Heart and Blood Vessels

Camcevi injections can increase the risk of heart attack, sudden death, and stroke. Your healthcare provider will monitor signs and symptoms suggestive of heart disease during treatment.

Irregular Heartbeat

Before prescribing Camcevi, a healthcare provider will determine whether the benefits of the drug outweigh the risks in people with existing heart rhythm problems, heart failure, or those who use medications that can cause irregular heartbeats.

Convulsions

Call your healthcare provider immediately if you have a seizure.

Before Taking Camcevi

Before you receive your first dose of Camcevi injection, inform your provider if you are allergic to this drug, any product component, or similar medications like goserelin (Zoladex), histrelin (Supprelin LA, Vantas), nafarelin (Synarel), or triptorelin (Triptodur, Trelstar).

Tell your provider if you have or ever had:

  • Seizures or epilepsy
  • A blood vessel disorder
  • A brain tumor or spinal cord injury
  • Depression, a mental disorder, or psychosis
  • Heart disease, such as heart failure or arrhythmia
  • Electrolyte imbalance (low blood levels of salts like potassium or magnesium)
  • Risk factors for bone loss (history of brittle bones, smoking, heavy drinking, long-term use of steroids or seizure medicines)

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Camcevi Introduction and Uses

Camcevi is a brand-name prescription medication. The active ingredient in this product is leuprolide, which is in a medication class called gonadotropin-releasing hormone (GnRH) agonists.

In 2021, the U.S. FDA approved Camcevi injections to treat adult males with advanced prostate cancer.

Camcevi Mechanism of Action

Camcevi causes your testes to produce less testosterone (androgen). Hence, this medication is also known as androgen deprivation therapy (ADT).

Camcevi Dosage

This medication comes as an off-white to pale yellow, viscous liquid in a single-dose, pre-filled syringe. Each Camcevi syringe contains 42 mg of the active drug.

A healthcare provider will inject Camcevi just under your skin. The common injection sites are the upper- or mid-abdominal areas with enough loose subcutaneous tissue.

The recommended Camcevi dosage is 42 mg leuprolide or one syringe every 6 months.

Camcevi Side Effects

Common Side Effects

Call your healthcare provider if the following symptoms worsen or don’t go away:

  • Hot flush
  • Joint pain
  • Dizziness
  • Tiredness
  • Frequent urination
  • Muscle or bone pain
  • Pain in the extremities
  • Increased urination at night
  • Infection of the upper airway
  • Decrease in the size of the testicles
  • Decrease in sexual ability or desire
  • Hypertension (elevated blood pressure)
  • Runny nose, cough, sore throat, or flu-like symptoms
  • Injection site reactions (pain, burning, bruising, redness)
A patient holding his knee in pain

Serious Side Effects

Call your healthcare provider immediately if you experience the following after receiving Camcevi:

  • Nausea
  • Vomiting
  • Seizures
  • Bone pain
  • Confusion
  • Dry mouth
  • Weakness
  • Blurred vision
  • Extreme thirst
  • Vision changes
  • Drooping eyelids
  • Blood in the urine
  • Sudden headache
  • Dizziness or fainting
  • Slow or difficult speech
  • Breath that smells fruity
  • Lowered consciousness
  • Difficulty moving the eyes
  • Painful, frequent, or difficult urination
  • Pain in your arms, back, chest, neck, or jaw
  • Weakness, numbness, or inability to move an arm or leg

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Allergic Reactions to Camcevi

Camcevi is a drug that may cause allergic reactions in some people. Seek emergency medical care if you experience:

  • Hives
  • Breathing difficulty
  • Swelling in the face or throat

Signs and Symptoms of Spinal Cord Compression

Seek emergency medical care if you experience the following after a Camcevi injection:

  • Loss of sensation in the feet
  • Weakness in the foot, causing a limp
  • Trouble with hand or leg coordination
  • Pain and stiffness in the neck, back, or lower back
  • Numbness, cramping, or weakness in the arms, hands, or legs
  • Burning pain that spreads to your arms, buttocks, or down into the legs

Use During Pregnancy and Lactation

Camcevi is FDA-approved for use only in adult men with advanced prostate cancer. However, other formulations of leuprolide may be used in children (boys and girls) to delay sexual development. Ask your pharmacist for more information.

Camcevi Cost

The cost of Camcevi can vary depending on your insurance plan, location, and pharmacy. Contact your insurance provider to find out if your plan covers this medication or if you need prior authorization.

Accord BioPharma, which is licensed to market the drug in the U.S. by Foresee Pharmaceuticals, offers support and resources to eligible patients.

You can also contact us if you are interested in receiving financial assistance.

Camcevi vs. Eligard

Both products contain the same active drug, leuprolide. Camcevi is a ready-to-use depot formulation, while Eligard requires mixing before administration. Also, Eligard is available in four different strengths and dosing schedules.

Camcevi vs. Lupron

Both Camcevi and Lupron injections contain the same active drug, leuprolide, but different salt forms. Moreover, the strengths, dosing schedules, and methods of administration differ.

Camcevi vs. Orgovyx

The active ingredient in Camcevi is leuprolide, while in Orgovyx, it is relugolix. Both products are used to treat advanced prostate cancer in men.

Unlike leuprolide, which is a gonadotropin-releasing hormone (GnRH) agonist, relugolix is a gonadotropin-releasing hormone (GnRH) antagonist.

How AmeriPharma® Specialty Pharmacy Can Help

Living with advanced prostate cancer can be challenging, but you don’t have to navigate it alone. AmeriPharma® Specialty Pharmacy offers personalized support for your treatment journey.

Our URAC-accredited specialty pharmacy provides access to essential medications like Camcevi. We also offer copay assistance and reliable 24/7 support across 40+ U.S. states and territories. Contact us today to talk to a specialist.

This information is not a substitute for medical advice or treatment. Talk to your doctor or healthcare provider about your medical condition prior to starting any new treatment. AmeriPharma® Specialty Care assumes no liability whatsoever for the information provided or for any diagnosis or treatment made as a result, nor is it responsible for the reliability of the content. AmeriPharma® Specialty Care does not operate all the websites/organizations listed here, nor is it responsible for the availability or reliability of their content. These listings do not imply or constitute an endorsement, sponsorship, or recommendation by AmeriPharma® Specialty Care. This webpage may contain references to brand-name prescription drugs that are trademarks or registered trademarks of pharmaceutical manufacturers not affiliated with AmeriPharma® Specialty Care.
Dr. Mark Alfonso
MEDICALLY REVIEWED BY Dr. Mark Alfonso, PharmD, BCMTMS

Dr. Mark Alfonso, PharmD was born and raised in Pueblo, CO. He received his pharmacy degree from the University of Colorado School of Pharmacy at the Anschutz Medical Campus in 2010. He was board certified in medication therapy management in 2022. The most rewarding part of his job is helping to answer patient questions and concerns. His areas of expertise are community pharmacy and medication therapy management. In his free time, he enjoys reading and running.

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