How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
Xyntha Solofuse Introduction and Uses
Xyntha Solofuse is a brand-name prescription medication. The active ingredient in this product is recombinant antihemophilic factor (rAHF), which is also known as coagulation factor VIII or moroctocog alfa.
Xyntha Solofuse belongs to a drug class called coagulation factors.
A healthcare provider may prescribe Xyntha Solofuse for adults and children with hemophilia A to:
- Treat and control bleeding episodes as they occur
- Manage bleeding before, during, and after surgery
- Reduce the frequency of bleeding episodes through routine preventive treatment
Xyntha Solofuse does not contain von Willebrand factor and is not indicated for the treatment of von Willebrand disease.
Xyntha Solofuse comes in a single-use, prefilled dual-chamber syringe. One chamber contains a white to off-white freeze-dried powder, and the other contains 4 ml of 0.9% sodium chloride solution. The powder must be mixed with the sodium chloride solution before intravenous (IV) infusion.
Xyntha Solofuse Mechanism of Action
People with hemophilia A have deficient or dysfunctional clotting factor VIII. Factor VIII is necessary for the blood-clotting process, and a deficiency can cause prolonged or spontaneous bleeding into the joints, muscles, or internal organs.
Xyntha Solofuse temporarily replaces the missing factor VIII, helping the blood form clots and control bleeding.
Before Using Xyntha Solofuse
Before using Xyntha Solofuse for the first time, tell your healthcare provider if you:
- Have had a severe allergic reaction to Xyntha Solofuse, any of its ingredients, or hamster proteins, which may be present in trace amounts
- Are pregnant or planning to become pregnant
- Are breastfeeding or planning to breastfeed
How Xyntha Solofuse Copay Assistance Works
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Dosing for the treatment and control of bleeding episodes
Minor bleeding: The dose is individualized to achieve a factor VIII activity level of approximately 20% to 40% of normal. Treatment may be repeated every 12 to 24 hours for at least 1 day, depending on the bleeding episode.
Moderate bleeding: The dose is individualized to achieve a factor VIII activity level of approximately 30% to 60% of normal. Treatment may be repeated every 12 to 24 hours for 3 to 4 days or until bleeding is adequately controlled.
Major bleeding: The dose is individualized to achieve a factor VIII activity level of approximately 60% to 100% of normal. Treatment may be repeated every 8 to 24 hours until the bleeding is controlled.
Dosing for perioperative bleeding management
Minor surgery: The dose is individualized to achieve a factor VIII activity level of approximately 30% to 60% of normal. Treatment may be repeated every 12 to 24 hours as directed by the healthcare provider.
Major surgery: The dose is individualized to achieve a factor VIII activity level of approximately 60% to 100% of normal. Treatment may be repeated every 8 to 24 hours until adequate wound healing is achieved. Treatment may then continue for at least another 7 days to maintain an appropriate factor VIII activity level, as directed by the healthcare provider.
Dosing for routine prevention of bleeding episodes
Recommended starting regimens include:
- Adults and adolescents 12 years or older: 30 IU/kg IV three times weekly
- Children younger than 12 years: 25 IU/kg IV every other day
Children younger than 12 may require higher or more frequent doses because the medication may be cleared from their bodies more quickly.
Your healthcare provider will adjust the dose or frequency based on your bleeding pattern, factor VIII levels, and clinical response.
Xyntha Solofuse Side Effects
Common side effects include:
- Headache
- Joint pain
- Fever
- Cough
- Vomiting
- Diarrhea
- Weakness
Serious side effects include:
Serious risks include severe allergic reactions and the development of factor VIII inhibitors.
Contact your healthcare provider about any side effect that concerns you or does not go away. Additionally, seek emergency medical care for signs of a serious allergic reaction.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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