How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Xgeva?
Xgeva (denosumab) is a brand-name prescription medication used to prevent bone-related complications in patients whose cancer has spread to the bones.
These complications can include bone fractures and pressure on the spinal cord. Xgeva can also be used to treat high blood levels of calcium caused by cancers when other medications are ineffective.
Xgeva is a monoclonal antibody. It helps you by reducing bone damage and increasing bone density. In clinical studies, researchers found that this medication was more effective than other drugs in preventing bone-related problems in cancer patients.
In patients with multiple myeloma, a type of blood cancer, Xgeva injections helped prevent bone-related complications for about 23 months.
What Is Xgeva Used To Treat?
Xgeva is FDA-approved for the following uses:
Prevention of Bone Fractures: Doctors use Xgeva to prevent bone fractures in adult patients with multiple myeloma and bone metastasis from solid tumors. Multiple myeloma is a type of blood cancer that affects the bone marrow. It can cause fractures in your bones, resulting in symptoms like pain in the back, ribs, hips, chest, or skull. Bone metastasis is a condition where cancer cells spread from their original location to the bones. Symptoms include neck and back pain, muscle weakness, fever, and low platelet count.
Treatment of Giant Cell Tumors of Bones: Doctors use this medication to treat adults and adolescents with giant cell tumors of the bone when the tumor cannot be completely removed through surgery or when surgery poses significant risks.
Treatment of Hypercalcemia Caused by Cancers: Hypercalcemia is a condition where there is too much calcium in the blood. It can cause complications in the bones, kidneys, stomach, brain, and heart. Xgeva is approved to treat adults with hypercalcemia caused by cancer, but only after they have tried a type of drug called bisphosphonate.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Xgeva Dosing Information
The dosage of Xgeva depends on several factors, such as your age, current condition, and medical history. Your doctor will determine the right dosage based on your situation. You will receive Xgeva as a subcutaneous injection in your upper arms, upper thighs, or abdomen. The usual recommended dose for different conditions is given below:
Multiple Myeloma and Bone Metastasis From Solid Tumors: The recommended dose is 120 mg every 4 weeks. If calcium levels in your blood become too low, you may also be prescribed calcium and vitamin D supplements.
Giant Cell Tumor of Bone: The recommended dose is 120 mg every 4 weeks. In your first month of Xgeva treatment, you will receive two additional 120 mg doses on Day 8 and 15. You will also receive calcium and vitamin D supplements if the calcium levels in your blood become too low.
Hypercalcemia Caused by Cancers: The recommended dose is 120 mg every 4 weeks with additional two 120 mg doses on Day 8 and Day 15 of the first month of treatment.
Xgeva Side Effects
Mild side effects include:
- Back and joint pain
- Nausea
- Difficulty breathing
- Tiredness and weakness
- Cough
- Headache
- Low levels of phosphate
- Appetite loss
- Toothache
- Swelling in your legs and arms
Severe side effects:
Anyone who uses Xgeva may experience severe side effects, such as:
Low Calcium Level in Blood: Xgeva can lower calcium levels in your blood. A low calcium level can cause symptoms like muscle spasms, stomach pain, extreme thirst, vomiting, and nausea.
Osteonecrosis of the Jaw: Xgeva injections can cause your jaw bones to die as it reduces blood supply to the jaw. As a result, patients can experience symptoms like jaw pain, numbness, swelling, and loose teeth. It is recommended that you maintain good oral hygiene and get regular dental check-ups while using this medication.
Allergic Reactions: Xgeva medication can cause severe allergic reactions in rare cases. Symptoms include rash, difficulty breathing, and itching.
Pneumonia: This is the most common severe side effect in multiple myeloma patients receiving Xgeva. Pneumonia is an infection of the lungs with symptoms like difficulty breathing, high fever, rapid breathing, cough, and rapid heart rate.
Please note that this is not a list of all possible side effects. Contact your provider immediately if you encounter any serious side effects after receiving Xgeva.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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