How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
Tolvaptan (Jynarque/Samsca) Introduction
Jynarque and Samsca are brand-name prescription medications. Both contain the same active ingredient, tolvaptan. However, these products treat different conditions and should not be used interchangeably.
Jynarque
Jynarque is used to slow kidney function decline in adults who are at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).
ADPKD is an inherited kidney disease in which fluid-filled sacs (cysts) form in the kidneys. These cysts gradually impair kidney function as they grow and may lead to kidney failure. There’s no cure for this condition.
Samsca
Samsca is used to treat clinically significant low blood sodium levels (hyponatremia) in certain adults, including some people with heart failure or Syndrome of Inappropriate Antidiuretic Hormone (SIADH).
Tolvaptan (Jynarque/Samsca) Mechanism of Action
Tolvaptan belongs to a class of medications called vasopressin V2 receptor antagonists. It works by blocking the effects of vasopressin, a hormone that normally causes the kidneys to retain water.
In people with ADPKD, blocking vasopressin V2 receptors helps reduce processes involved in kidney cyst growth and slows the decline in kidney function.
Tolvaptan also causes the kidneys to remove more water through urine without proportionally increasing sodium loss. In people with certain types of hyponatremia, this loss of excess water can help increase the concentration of sodium in the blood.
How Tolvaptan Copay Assistance Works
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Tolvaptan (Jynarque/Samsca) Dosing
Jynarque
The starting total dose is 60 mg orally per day, which is divided into: 45 mg upon waking and 15 mg 8 hours later. If tolerated, the dose may be increased to 90 mg orally per day (60 mg upon waking and 30 mg 8 hours later).
The highest dose is 120 mg orally per day (90 mg upon waking and 30 mg 8 hours later).
Samsca
The usual starting dose is 15 mg orally with or without food. The dose may be increased to 30 mg orally once daily after at least 24 hours. The maximum dose is 60 mg orally once daily. Don’t take this medication for longer than 30 days in order to reduce the risk of liver injury.
Tolvaptan Side Effects
Common side effects of Jynarque:
- Thirst
- Drinking more fluid than normal
- Frequent urination
- Increased urine output
- Urinating at night
Severe side effects of Jynarque:
- Hypernatremia (elevated blood sodium levels)
- Dehydration and hypovolemia (loss of too much fluid from the body)
Common side effects of Samsca:
- Thirst
- Dry mouth
- Weakness
- Constipation
- Frequent urination
- Increased urine output
- Elevated blood glucose levels
Severe side effects of Samsca:
Call your healthcare provider immediately if you have signs of dehydration, such as dizziness or feeling like you are going to pass out. Tell your healthcare provider if you have vomiting or diarrhea and difficulty drinking fluids.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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