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Over $55 million secured for our patients to date

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We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances.

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How Targretin Copay Assistance Works

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1 – Check Your Coverage/Benefits Verification

Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

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2 – Transfer Prescription to AmeriPharma

We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

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3 – Prior Authorization

Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

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4 – Copay Assistance & Financial Aid

We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma Specialty Care has secured $55 million in financial assistance for our patients.

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5 – Nursing Care Coordination

AmeriPharma puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

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6 – Delivery Coordination

Medications are always delivered in strict compliance with the specific requirements for immune globulin shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

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We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

What Is Targretin?

Targretin is the trade name for a drug known as bexarotene. Targretin is an anti-cancer agent used to treat the symptoms of cutaneous t-cell lymphoma (CTCL). This drug belongs to the drug class known as antineoplastic retinoic acid derivatives, or retinoids, which are metabolites of vitamin A (retinol). It is a third-generation retinoid. 

Targretin works effectively when used alone as a treatment for CTCL and when combined with other treatment methods. While the research on the efficacy of this medication is sparse, some studies showed that the drug is effective in treating symptoms of cutaneous t-cell lymphoma. 

In one of these studies, there was an overall response rate of 75%, and researchers noticed a better response rate with early-stage cases than with advanced-stage cases. The average response time was three months, and the average response lasted 21 months.

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We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

What Is Targretin Used For?

Targretin is used to treat symptoms of a rare cancer type known as cutaneous t-cell lymphoma, such as skin tumors and skin lesions. The drug is usually administered after other treatments and therapy for cancer have failed. 

How Does Targretin Work?

Bexarotene selectively binds to retinoid X receptors (RXRs) and activates them. Once activated, RXRs function as transcription factors, regulating the expression of genes that control cellular differentiation and proliferation. 

With the activation of these receptors, Targretin causes cell differentiation and apoptosis, which is needed to prevent drug resistance development. This activation also allows it to prevent cancer metastasis and induce the drug’s angiogenic effects.

Copay and Financial Assistance

AmeriPharma Specialty Care alleviates financial burdens for patients and their families

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We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

Targretin Side Effects

Some of the side effects you may experience include:

  • Vomiting
  • Itching
  • Insomnia
  • Diarrhea
  • Nausea
  • Headache
  • Rash
  • Dry skin

All of these symptoms usually last for only a few days. You should talk to your doctor if they last any longer. 

There may also be more serious side effects, such as:

  • Hypothyroidism (underactive thyroid gland)
  • High blood cholesterol
  • Reduced white cell count
  • Hyperlipaemia (high levels of fat in the body) 

Keep in mind that most patients do not experience any side effects, and this is in no way an exhaustive list. If you experience any reactions that are not on this list, don’t hesitate to call your doctor.

Schedule a Consultation

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

Dosage

Targretin should be used only when prescribed, and its administration should be supervised by a doctor with experience using Targretin for treating CTCL. 

The drug is available in a 75 mg capsule. However, the ideal dose depends on the surface area of the patient’s skin. This surface area is measured in square meters, and the recommended initial dose is 300 mg/square meter daily. This drug is to be taken once a day and with meals. 

This dose can then be increased or decreased depending on the patient’s response to the treatment and the side effects that manifest. The drug administration should also continue as long as the patient benefits from the drug. 

Note that none of the information provided above supersedes the instruction provided by the pharmacist or doctor. You can check the leaflet attached to the drug for more information. 

Overdose

If you accidentally take too much Targretin, call your doctor immediately. In extreme cases, such as those involving difficulty breathing or passing out, call the nearest poison center or 911. 

If you missed a dose, you should take it with a meal as soon as you remember. If it is almost time to take the next dose, you can skip the missed dose and simply take the next dose. Do not take a double dose to make up for a missed dose.

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