Sirolimus Copay Assistance

How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

1. Check Your Coverage/Benefits Verification

Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
2. Transfer Prescription to AmeriPharma®

We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
3. Prior Authorization

Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
4. Copay Assistance & Financial Aid

We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
5. Nursing Care Coordination

AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
6. Delivery Coordination

Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

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What Is Sirolimus?

Sirolimus is an immunosuppressant (available as a tablet and solution) used with other drugs to help prevent the rejection of a transplanted kidney. It’s also available as a topical sirolimus gel used to treat a skin condition.

Sirolimus (Rapamycin) is an immunosuppressant medication, meaning it lowers the activity of your immune system. It’s available as an oral version (Rapamune) and topical version (Hyftor). Both Rapamune and Hyftor are available as generic versions.

What Is Sirolimus Used To Treat?

Rapamune (sirolimus tablet and liquid) is FDA-approved to prevent the body from rejecting a transplanted kidney in individuals 13 years or older. It’s also used to treat a lung disease called lymphangioleiomyomatosis (LAM), which is a rare disease that causes abnormal growth of smooth muscle cells in your lungs and lymphatic system.

Hyftor (sirolimus topical gel) is a prescription topical medication that treats a condition called facial angiofibroma, which is a specific type of facial lesion, in adults and children 6 years and older.

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What Should You Know Before Taking Sirolimus?

Before receiving your first dose, inform your provider if you have:

Liver disease
Skin cancer or a family history of skin cancer
High cholesterol or triglycerides in your blood

Also, since sirolimus can interact with a lot of commonly used medications, make sure to tell your provider about all of the medications you take, including prescription and over-the-counter medications as well as vitamins and dietary supplements. Some examples of medications that interact with sirolimus include:

Cholesterol-lowering medicine
Cyclosporine, tacrolimus, or other immunosuppressants
Antibacterial or antifungal medicines
Medications to lower blood pressure
Heart disease drugs
Medicines for seizures
HIV drugs
St. John’s Wort
Cannabidiol

Copay and Financial Assistance

AmeriPharma™ Specialty Pharmacy alleviates financial burdens for patients and their families

Advanced software locates funding sources to match you with top-dollar foundation programs
One of our copay assistance specialists will assist with the application process
Automatic updates will be sent to you and your physician on the status of the funding

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Oral Sirolimus Dosage

Prevention of Kidney Transplant Rejection

You should receive your first dose as soon as possible after transplantation. This medication is typically used with cyclosporine and corticosteroids.

Your provider will calculate the starting dose based on your body weight or body surface area and the estimated risk of rejection of the transplanted kidney. Then, they will adjust the dose (maintenance dose) to achieve the desired blood concentration of sirolimus. The maximum dose is 40 mg per day.

Treatment of Lymphangioleiomyomatosis (LAM)

The initial dose is 2 mg/day. Your provider will determine the trough level, usually between days 10 and 20. Then, they will adjust the dosage accordingly based on the level in your blood.