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How Sirolimus Copay Assistance Works
1 – Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
2 – Transfer Prescription to AmeriPharma
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
3 – Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
4 – Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma Specialty Care has secured $55 million in financial assistance for our patients.
5 – Nursing Care Coordination
AmeriPharma puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
6 – Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for immune globulin shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Sirolimus?
Sirolimus is an immunosuppressant (available as a tablet and solution) used with other drugs to help prevent the rejection of a transplanted kidney. It’s also available as a topical sirolimus gel used to treat a skin condition.
Sirolimus (Rapamycin) is an immunosuppressant medication, meaning it lowers the activity of your immune system. It’s available as an oral version (Rapamune) and topical version (Hyftor). Both Rapamune and Hyftor are available as generic versions.
What Is Sirolimus Used To Treat?
Rapamune (sirolimus tablet and liquid) is FDA-approved to prevent the body from rejecting a transplanted kidney in individuals 13 years or older. It’s also used to treat a lung disease called lymphangioleiomyomatosis (LAM), which is a rare disease that causes abnormal growth of smooth muscle cells in your lungs and lymphatic system.
Hyftor (sirolimus topical gel) is a prescription topical medication that treats a condition called facial angiofibroma, which is a specific type of facial lesion, in adults and children 6 years and older.
What Should You Know Before Taking Sirolimus?
Before receiving your first dose, inform your provider if you have:
- Liver disease
- Skin cancer or a family history of skin cancer
- High cholesterol or triglycerides in your blood
Also, since sirolimus can interact with a lot of commonly used medications, make sure to tell your provider about all of the medications you take, including prescription and over-the-counter medications as well as vitamins and dietary supplements. Some examples of medications that interact with sirolimus include:
- Cholesterol-lowering medicine
- Cyclosporine, tacrolimus, or other immunosuppressants
- Antibacterial or antifungal medicines
- Medications to lower blood pressure
- Heart disease drugs
- Medicines for seizures
- HIV drugs
- St. John’s Wort
Copay and Financial Assistance
AmeriPharma Specialty Care alleviates financial burdens for patients and their families
Advanced software locates funding sources to match you with top-dollar foundation programs
One of our copay assistance specialists will assist with the application process
Automatic updates will be sent to you and your physician on the status of the funding
Sirolimus Side Effects
Side effects can be mild or severe. Furthermore, they may vary depending on the condition for which the drug is being used.
Common Side Effects
- High blood pressure
- Urinary tract infection
- Stomach pain
- Joint pain
- Chest pain
- Low red blood cell count
- Low platelet count
- High blood sugar
- Mouth sores
- Upper respiratory tract infection
- Sore throat
Talk to your provider or pharmacist if any side effect worsens or persists.
Severe Side Effects
Call your provider immediately or seek emergency care if you have:
- Swelling of your hands or feet
- Poor wound healing
- Unusual bleeding or bruising
- New or worsening cough
- Shortness of breath
- Breathing difficulty
- Signs of viral infection, including confusion, altered consciousness, and weakness on one side of your body
Seek emergency medical help if you experience the following:
- Chest pain
- Shortness of breath
- High or low blood pressure
Oral Sirolimus Dosage
Prevention of Kidney Transplant Rejection
You should receive your first dose as soon as possible after transplantation. This medication is typically used with cyclosporine and corticosteroids.
Your provider will calculate the starting dose based on your body weight or body surface area and the estimated risk of rejection of the transplanted kidney. Then, they will adjust the dose (maintenance dose) to achieve the desired blood concentration of sirolimus. The maximum dose is 40 mg per day.
Treatment of Lymphangioleiomyomatosis (LAM)
The initial dose is 2 mg/day. Your provider will determine the trough level, usually between days 10 and 20. Then, they will adjust the dosage accordingly based on the level in your blood.