How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Nivestym?
Nivestym (filgrastim-aafi) is an FDA-approved medicine used to treat neutropenia (low levels of neutrophils, a type of white blood cell) caused by chemotherapy, bone marrow transplant, or some other condition. It is a synthetic version of the naturally occurring protein called granulocyte colony-stimulating factor (G-CSF), which promotes white blood cell production.
The FDA first approved Nivestym on July 20, 2018, as a biosimilar to Neupogen [1]. This means that there is no clinical difference between Nivestym and Neupogen, but Nivestym is less expensive.
How Does Nivestym Work?
Neutrophils are a kind of white blood cell that fight bacterial and fungal infections. They are produced in your bone marrow. Unfortunately, chemotherapy and radiation therapy can harm your bone marrow, which can reduce or stop neutrophil production. This increases your chance of having serious infections.
Nivestym is a synthetic version of a naturally occurring protein called granulocyte colony-stimulating factor (G-CSF). It works by encouraging your bone marrow to:
- Produce more neutrophils
- Speed up neutrophil production
- Release neutrophils into the bloodstream
As a result, your neutrophil count increases faster, reducing the time your immune system is weakened after chemotherapy.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
What Is Nivestym Used To Treat?
Nivestym (filgrastim-aafi) is a medicine that helps your body make more white blood cells, which help fight infections. It is FDA-approved for the following purposes:
Chemotherapy-Induced Neutropenia: This medication can reduce the risk of infection in cancer patients receiving intensive chemotherapy that can lower white blood cell counts and cause fever.
Acute Myeloid Leukemia: Nivestym can help white blood cells recover faster and shorten the duration of fever in patients with acute myeloid leukemia (AML) after extensive chemotherapy.
Bone Marrow Transplant: After a bone marrow transplant, Nivestym can speed up white blood cell recovery and reduce the duration of severe neutropenia.
Peripheral Blood Progenitor Cell Collection: Nivestym is used to move blood-forming stem cells into the bloodstream so they can be collected and used later for treatment.
Severe Chronic Neutropenia: Nivestym can help patients with long-term neutropenia, including congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia. It can reduce infections and related problems, such as fever and mouth sores.
Nivestym Side Effects
Common side effects include:
- Bone Pain
- Muscle Pain
- Headache
- Fatigue
- Nausea
- Injection site reaction (redness, swelling, or pain)
- Diarrhea and vomiting
Severe Side Effects
Spleen Rupture: In rare cases, Nivestym can cause rupture in your spleen, which can be fatal. Symptoms include pain in the upper left abdomen or shoulder.
Acute Respiratory Distress Syndrome (ARDS): Nivestym can cause ARDS in some patients. Symptoms include shortness of breath, rapid breathing, and low oxygen levels.
Serious Allergic Reactions: You may experience allergic reactions to Nivestym, particularly with the initial dose. Symptoms include rash, swelling of the face or throat, dizziness, or difficulty breathing.
Capillary Leak Syndrome: This is a rare but serious condition where fluid leaks from your blood vessels. This leads to low blood pressure and swelling.
Sickle Cell Disorders: Nivestym can cause sickle cell crisis in patients with sickle cell disorder. This can be fatal. Discontinue Nivestym if a sickle cell crisis occurs.
Low Platelet Count: Nivestym can lower your platelet count, which can be severe.
Kidney Problems: Nivestym can cause inflammation in your kidneys. Symptoms include dark-colored urine and swelling in the face, hands, or feet.
Please note that this is not a complete list of all possible side effects. Consult your doctor immediately if you experience any severe side effects of Nivestym.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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