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Directions for Use

Lupron injections can be given every day, once a month, or once every several months, depending on the condition treated. Verify the correct dose and frequency with your provider. The dose should not be more or less than what is prescribed. Most of the time, it is administered by a health care provider but can be self-administered as well. Wash hands before and after injection.

General injection administration instructions:

• Use a new needle and syringe every time you inject the medicine.
• Do not concurrently administer partial doses of different formulations or combine different doses.
• Avoid using a combination of syringes to achieve a particular dose.
• Choose an injection site that does not have skin discoloration, nodules, lesions, scars, or excess hair.
• Avoid areas that may be compressed or rubbed (e.g., belt or waistband area).
• If a syringe is required, use insulin syringes.
• Alternate injection sites periodically.

Brand-specific injection information:

• Intramuscular Lupron Depot injections: Administer within 2 hours of preparation as a single injection into the gluteal area, outer thigh, or upper arm.
• Subcutaneous leuprolide acetate injections: Inject into areas on the arm, thigh, or abdomen.
• Subcutaneous Eligard injections: Administer within 30 minutes of preparation to an area with adequate tissue like the upper or mid-abdomen or upper buttocks area.
• Subcutaneous Fensolvi injections: Fensolvi should be administered by a health care professional as a single subcutaneous injection into the abdomen, upper buttocks, or other location with adequate tissue.