How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Jivi?
Jivi (damoctocog alfa pegol) is an FDA-approved medicine used to control or prevent bleeding episodes in patients with Hemophilia A. Hemophilia A is a genetic disorder caused by a lack of clotting factor VIII (a protein needed for normal blood clotting).
Jivi is a man-made version of clotting factor VIII that is chemically modified to last longer in the body. It was developed by Bayer, and the FDA first approved it in August 2018 for use in children and adults with Hemophilia A.
You can get this medication through an IV infusion, and it is designed to give you longer protection compared to other factor VIII products.
What Is Jivi Used To Treat?
Jivi is a factor VIII replacement medicine. Factor VIII is a protein that is needed to clot blood properly. Jivi is used to treat people with hemophilia A, a condition where the body does not have enough factor VIII.
Jivi can be used in adults and children aged 7 or older who have taken factor VIII replacement therapy before. It is FDA-approved for:
- Treating bleeding episodes when they happen
- Controlling bleeding during and after a surgery
- Regular preventive treatment to reduce the frequency of bleeding episodes
Please note that Jivi is not recommended for children under 7 years of age, people who never received factor VIII therapy, or people who have Von Willebrand disease.
How Does Jivi Work?
Factor VIII is a protein that your body needs to form blood clots properly. In people with hemophilia A, the body does not produce enough functional factor VIII. As a result, they experience prolonged or frequent bleeding episodes.
Jivi is a laboratory-made factor VIII medicine. It works by replacing the missing clotting factor VIII in people with hemophilia A. The notable feature of Jivi is that it has been modified by attaching it to a substance called PEG (polyethylene glycol). This modification slows down the rate at which Jivi is removed from the body.
As a result, Jivi stays in your bloodstream for a longer time. Thus, you get longer-lasting protection against bleeding.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Dosing
Jivi is available as a lyophilized powder in single-dose vials. Your doctor will reconstitute it before using. You will receive this drug through intravenous infusion. The dosage and frequency of Jivi infusion depend on your weight, the severity of your disease, and your treatment goal. Here is the usual recommended dosage of Jivi:
Treatment of Bleeding Episodes and Surgical Use: The dosing is based on how much the patient’s factor VIII level needs to increase. The required dose is calculated using your body weight and the desired increase in factor VIII activity. Your doctor will determine the right dose for you.
Prevention of Bleeding: Here is the usual dosage that you must take regularly to prevent bleeding:
- For adults and children aged 12 years or older, the usual starting dose is 30-40 IU/kg twice weekly. If bleeding continues, the dosage can be adjusted to 45-60 IU/kg every 5 days.
- For children aged 7-11 years, the recommended starting dose is 60 IU/kg. Your doctor will adjust the dose based on clinical response and factor VIII recovery.
Jivi Side Effects
Common side effects include:
- Fever
- Cough
- Headache
- Abdominal pain
Serious Side Effects
Although rare, Jivi can cause serious side effects. Here are some of them:
Severe Allergic Reactions: Jivi can cause allergic reactions, which can be severe. Symptoms include rash, itching, swelling of the face or throat, difficulty breathing, nausea or vomiting, and stomach cramps. If an allergic reaction occurs, stop using Jivi immediately and contact your doctor.
Development of Factor VIII Inhibitors: You may develop inhibitors (antibodies) that reduce the effectiveness of Jivi. If bleeding does not stop as expected, your doctor may conduct a blood test to check the factor VIII levels in the blood to confirm whether they are lower than they should be.
Immune Reaction to PEG: The immune system of some patients may react to PEG (a substance in Jivi). This can lead to sudden allergic reactions or make Jivi less effective.
Please note that this is not a complete list of all possible side effects. If you experience any unusual or severe symptoms, contact your doctor immediately.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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