How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
Humate-P Introduction and Uses
Humate-P is a brand-name product. It belongs to a drug class called coagulation factors or hemostatics. Humate-P contains two factors:
- Antihemophilic factor (Factor VIII [FVIII])
- von Willebrand factor (VWF)
Together, these proteins help replace clotting factors that are missing or deficient, allowing blood to clot more effectively and reducing bleeding.
This medication is FDA-approved to:
- Prevent or treat bleeding in adults with hemophilia A
- Treat bleeding episodes and prevent excessive blood loss during or after surgery in patients of all ages with von Willebrand disease. This medication may be used for all types of VWD.
Humate-P comes as a powder for reconstitution (preparing a solution by mixing with the provided liquid) in a single-dose vial.
Humate-P Mechanism of Action
Humate-P temporarily replaces deficient or missing von Willebrand factor and factor VIII. VWF helps platelets stick to damaged blood vessels to form a clot, while FVIII works with other clotting proteins to stabilize the clot and stop bleeding.
Before Taking Humate-P
Don’t take this medication if you have a history of severe allergic reactions to antihemophilic factor.
Before you receive the first dose of this medication, inform your healthcare provider if you are:
- Pregnant or plan to get pregnant
- Breastfeeding or plan to breastfeed
Also tell your healthcare provider if you:
- Have a history of blood clots.
- Have heart disease or other cardiovascular risk factors.
- Have any known allergies to plasma-derived products.
- Are taking medications that increase the risk of blood clots.
How Humate-P Copay Assistance Works
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Humate-P Dosing
Hemophilia A
Your healthcare provider will determine your dose based on:
- Your body weight
- Type and severity of hemorrhage
- FVIII level
- Presence of inhibitors (antibodies that can make this medication less effective)
Minor bleeding: Loading dose is 15 IU/kg IV; should achieve FVIII:C plasma level ~30% of normal; may repeat using 50% of loading dose once or twice daily for 1-2 days.
Moderate bleeding: Loading dose is 25 IU/kg IV; should achieve FVIII:C plasma level ~50% of normal, followed by 15 IU/kg every 8 to 12 hours for 1 to 2 days to maintain FVIII:C levels at 30% normal, and then the same dose once or twice daily for up to 7 days or until adequate wound healing.
Life-threatening bleeding: 40-50 IU/kg IV initially, followed by 20-25 IU/kg every 8 to 12 hours to maintain FVIII:C level at 80% to 100% of normal for 7 days, then continue the same dose once or twice daily for another 7 days to maintain FVIII:C level at 30% to 50% of normal.
Von Willebrand Disease
For the treatment of bleeding episodes, your healthcare provider will determine the dosage based on the extent and location of bleeding. The typical dose is 40 to 80 International Units (IU) VWF:RCo per kg body weight every 8 to 12 hours. Doses may be repeated as long as needed based on laboratory findings.
For preventing excessive bleeding during and after surgery, your healthcare provider will use a specific formula to calculate the dose. The loading dose for an emergency surgery is 50 to 60 International Units VWF:RCo/kg body weight.
Humate-P Side Effects
Common side effects include:
- Mild allergic reactions (rash, itching, or swelling)
- Injection-site bleeding
- Nosebleeds
Severe side effects include:
Allergic reactions
This medicine may cause allergic reactions, including anaphylaxis. Anaphylaxis is a potentially fatal allergic reaction that causes difficulty breathing and low blood pressure.
Seek immediate medical care if you develop the following symptoms after receiving this medication:
- Rash and itching
- Hoarseness
- Breathing difficulty
- Trouble swallowing
- Swelling of your hands, face, or mouth
- Chest tightness
- Low blood pressure
Blood clots
Using Humate-P may increase the risk of potentially serious blood clots in patients with von Willebrand disease. Patients with known risk factors for blood clots and those undergoing surgery may be at a higher risk of developing blood clots.
Seek immediate medical attention if you develop symptoms of a blood clot, such as:
- Sudden chest pain
- Shortness of breath
- Swelling or pain in one leg
- Sudden weakness or numbness
- Difficulty speaking
Risks of infection transmission
See the Important Humate-P Warnings section above for more information about the small theoretical risk of transmitting infectious agents from plasma-derived products.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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