How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

  • 1. Check Your Coverage/Benefits Verification

    Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

  • 2. Transfer Prescription to AmeriPharma™

    We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

  • 3. Prior Authorization

    Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

  • 4. Copay Assistance & Financial Aid

    We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma™ Specialty Care has secured $55 million in financial assistance for our patients.

  • 5. Nursing Care Coordination

    AmeriPharma™ puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

  • 6. Delivery Coordination

    Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

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What Is Hizentra?

Hizentra belongs to the class of medications called Immune Globulin Subcutaneous (Human). It is used to treat primary immunodeficiency conditions, and people who use this medication are said to be undergoing immune globulin therapy. Hizentra is used for the treatment of weakened immune activity and nerve conditions such as demyelinating polyneuropathy.

The U.S. Food and Drug Administration (FDA) first endorsed the medication in 2010. Since then, It has gained widespread popularity, becoming the world’s most prescribed immunoglobulin medication with up to 9.3 million exposures to date.

The color of Hizentra runs from clear and pale yellow to light brown. The medication is available in pre-filled syringes and vials.

While some people prefer syringes, others may feel more secure using vials. Your physician can help you make an informed decision. The syringes always come in volumes ranging from 5 to 20 ml. The vials are available in volumes ranging from 5 to 50 ml.

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How Does Hizentra Work?

Hizentra’s active ingredient, human immunoglobulin, is a highly purified protein derived from the plasma of healthy individuals. It acts as the body’s soldier to ward off bacterial and viral infections, and it helps create a balanced immune system.

One way the immune system can become unbalanced is when it becomes hyperactive, a condition known as autoimmunity. Hizentra modifies the immune hyperactivity through a mechanism called immunomodulation, in which the hyperactivity is regulated in order to prepare the body against potential threats.


Who Can Use Hizentra?

Adults and children over two years old can use Hizentra. Patients who use this medication are often those who suffer from nerve disorders such as chronic inflammatory demyelinating polyneuropathy and immune system diseases such as:

  • Humoral immune defect in congenital agammaglobulinemia
  • Common variable immunodeficiency
  • X-linked agammaglobulinemia
  • Wiskott-Aldrich syndrome
  • Severe combined immunodeficiencies

Copay and Financial Assistance

AmeriPharma™ Specialty Care alleviates financial burdens for patients and their families

  • Advanced software locates funding sources to match you with top-dollar foundation programs

  • One of our copay assistance specialists will assist with the application process

  • Automatic updates will be sent to you and your physician on the status of the funding

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Hizentra Dosing

Hizentra must be used according to doctors’ instructions. Hizentra is administered subcutaneously through a needle that is positioned under the skin; it can be administered by a healthcare professional or self-administered after proper training.

Hizentra must be administered in steady amounts. Individuals may utilize up to eight different infusion sites to infuse this medication in multiple body areas.

Avoiding Adverse Effects:

  • The doctor or pharmacist will quantify the correct dosage based on the patient’s weight and response to treatment.
  • It is not advisable to change the dosage intervals without consulting a physician.
  • If a patient misses a dose, they can contact the doctor to modify the dosage plan.
  • If a patient overuses the dose, they should seek medical help.
  • Patients are advised against consuming large doses in an attempt to achieve quicker results. The consequences may be fatal.

Other Dosage and Usage Requirements:

  • Do not use the medication if it is cloudy or has other colors.
  • Do not use the medication if there are particles in it.
  • Do not shake the Hizentra vial or pre-filled syringe.
  • Make sure that you do not infuse the drug into your vein.
  • Make sure you assemble the Hizentra supplies like needles in a clean place.
  • Wash your hands before and after every use.
  • Discard any unused product and all used disposable supplies after each infusion.

Common Side Effects

Reactions around the injection site:
  •   Rash
  •   Pain
  •   Redness
  •   Swelling
  •   Itching
  •   Bruising
Other side effects:
  • Headache
  • Flu-like symptoms
  • Hypertension
  • Pain  (including pain in the chest, back, joints, arms, legs)
  • Blood clot
  • Cough
  • Shortness of breath
  • Runny or stuffy nose

Serious Side Effects

If the following side effects are observed, tell your doctor right away or go to the emergency room.

Signs of a bad allergic reaction:
  • Hives
  • Trouble breathing
  • Wheezing
  • Dizziness
  • Fainting
Signs of a kidney problem:
  • Reduced urination
  • Sudden weight gain
  • Swelling in your legs
Signs of a blood clot:
  • Pain or swelling of an arm or leg with warmth over the affected area.
  • Discoloration of an arm or leg.
  • Unexplained shortness of breath, chest pain, or discomfort that worsens on deep breathing.
  • Unexplained rapid pulse, or numbness or weakness on one side of the body.
Signs of a blood problem:
  • Brown or red urine
  • Fast heart rate
  • Yellow skin or eyes
Signs of brain swelling called meningitis:
  • Bad headache with nausea, vomiting, stiff neck, fever, and sensitivity to light.
Signs of an infection:
  • Fever over 100ºF

Insurances Accepted

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

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Get Started in Minutes

Fill out your information and one of our specialists will call you ASAP.

How Much Can You Save?

Speak with a copay assistance specialist

(877) 778-0318

HIPAA Compliant