How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Fylnetra?
Fylnetra (pegfilgrastim-pbbk) is a prescription medicine used to prevent infections in patients receiving chemotherapy that may lower their white blood cell (neutrophil) counts. It is a biosimilar to Neulasta (pegfilgrastim). This means that there is no meaningful clinical difference between Fylnetra and Neulasta, but the price of Fylnetra is less.
Amneal Pharmaceuticals LLC developed Fylnetra, and the FDA first approved it on May 26, 2022. It belongs to a class of drugs called colony-stimulating factors (CSF). CSFs help stimulate your bone marrow to produce more white blood cells (neutrophils), which play a crucial role in fighting infections.
By helping your body make more white blood cells, Fylnetra reduces the risk of infections that often come with certain chemotherapy treatments. You can receive this drug as a subcutaneous injection (an injection under the skin).
What Is It Used To Treat?
Fylnetra (pegfilgrastim-pbbk) is an FDA-approved medication used for the following two purposes:
Prevention of infection in cancer patients receiving myelosuppressive chemotherapy who have a significant risk of febrile neutropenia: Fylnetra can reduce the risk of infection in patients with non-myeloid cancers who are receiving myelosuppressive chemotherapy (cancer treatments that can significantly lower white blood cell counts). By boosting white blood cell production, Fylnetra helps protect the body against infections during chemotherapy.
Improvement of survival in patients with Hematopoietic Subsyndrome of Acute Radiation Syndrome (ARS): This is a condition caused by acute exposure to myelosuppressive doses of radiation, which damages the bone marrow and reduces your ability to produce blood cells and fight infection. Fylnetra can increase survival in these patients by stimulating the bone marrow, helping patients rebuild their white blood cell levels.
How Does Fylnetra Work?
Chemotherapy targets rapidly dividing cells to destroy cancer cells. However, in the process, chemotherapy can also harm healthy cells, including those in the bone marrow, where blood cells are produced. This damage can lead to a drop in neutrophils (a type of white blood cell). When neutrophil levels are too low, you are more prone to infections.
Fylnetra contains pegfilgrastim. It is a man-made version of a natural protein in the body called granulocyte colony-stimulating factor (G-CSF). Fylnetra works by stimulating the bone marrow to make more neutrophils.
Unlike some similar medications (e.g., filgrastim), Fylnetra stays in your body for a longer time. Because of this, you need to take it only once per chemotherapy cycle.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Dosing and Administration
Fylnetra is available as a single-dose prefilled syringe, which is given subcutaneously (under the skin). Before using, inspect the syringe, and if you see any discoloration or particulates, discard it. The usual recommended dosage is given below:
For patients with cancer receiving myelosuppressive chemotherapy: The recommended dose is 6 mg, administered subcutaneously (under the skin) once per chemotherapy cycle. Do not administer Fylnetra within 14 days before or 24 hours after receiving cytotoxic chemotherapy.
For patients acutely exposed to myelosuppressive doses of radiation: These patients will receive two 6 mg doses one week apart. The first dose is given as soon as possible after suspected or confirmed radiation exposure, and the second dose is given one week later.
Fylnetra Side Effects
Common Side Effects
- Bone pain
- Pain in arms or legs
- Back pain
- Fatigue
These side effects are usually mild and go away within a few days. However, if these symptoms persist or worsen, consult your doctor.
Serious Side Effects
In rare cases, Fylnetra can cause some serious side effects. If you encounter any of these severe side effects, contact your doctor immediately. Here are some of those serious side effects:
Fatal Splenic Rupture: Fylnetra can cause your spleen to become large, which can rupture and cause death. Symptoms of an enlarged spleen include pain in the left upper abdomen or shoulder tip.
Serious Allergic Reactions: You may experience symptoms like rashes, swelling, shortness of breath, or dizziness after injection. Discontinue permanently if you experience allergic reactions.
Acute Respiratory Distress Syndrome (ARDS): This serious lung condition can cause shortness of breath, fever, and fast breathing.
Fatal Sickle Cell Crises: In patients with sickle cell disease, Fylnetra can cause a severe sickle cell crisis (a painful episode). Discontinue use if a sickle cell crisis occurs.
Aortitis (Inflammation of the Aorta): Symptoms include fever, fatigue, and pain in the chest, back, or abdomen.
Kidney Problems: Fylnetra can damage your kidneys. Symptoms include dark urine, swelling in your face or legs, and little to no urination.
Capillary Leak Syndrome (CLS): This condition occurs when fluid and proteins leak out of your small blood vessels (capillaries) into surrounding tissues. This leads to low blood pressure, low levels of albumin in your blood, swelling, fatigue, shortness of breath, and diarrhea.
Please note that this is not a complete list of all possible side effects. Always consult your doctor if you experience any unusual symptoms.
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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