How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

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    1. Check Your Coverage/Benefits Verification

    Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

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    2. Transfer Prescription to AmeriPharma®

    We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

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    3. Prior Authorization

    Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

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    4. Copay Assistance & Financial Aid

    We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.

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    5. Nursing Care Coordination If Needed

    AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

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    6. Delivery Coordination

    Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

Introduction and Uses

Esperoct is a brand-name prescription product. The active ingredient in this product is turoctocog alfa pegol. It is a lab-created form of factor VIII, also known as recombinant antihemophilic factor.

Because the active ingredient is conjugated with a polyethylene glycol molecule, Esperoct stays in the body longer than standard half-life factor VIII products. This extends factor VIII activity in the body.

Esperoct belongs to the drug class called coagulation factors or hemostatics.

A healthcare provider may prescribe Esperoct for adults and children with hemophilia A to:

  • Treat and control bleeding episodes
  • Manage bleeding around surgery
  • Provide routine prophylaxis to reduce the frequency of bleeding episodes

This medication should not be used to treat von Willebrand disease (VWD).

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Mechanism of Action

People with hemophilia A have deficient or dysfunctional clotting factor VIII. Factor VIII is necessary for the blood-clotting process. Its deficiency can cause prolonged or spontaneous bleeding into the joints, muscles, or internal organs.

Esperoct works by temporarily replacing the missing clotting factor VIII in the blood, helping the blood form clots and control bleeding.

Before Taking Esperoct

Before using Esperoct, tell your healthcare provider if you:

  • Have any known allergies
  • Have or have had any medical conditions
  • Have or have previously developed factor VIII inhibitors
  • Are breastfeeding
  • Are pregnant or planning to get pregnant

Don’t use Esperoct if you are allergic to factor VIII, any ingredients of Esperoct, or hamster proteins.

How Esperoct Copay Assistance Works

AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families

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    Advanced software locates funding sources to match you with top-dollar foundation programs

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    One of our copay assistance specialists will assist with the application process

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    Automatic updates will be sent to you and your physician on the status of the funding

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Esperoct Dosing

Your healthcare provider will calculate your dose based on your body weight, desired increase in factor VIII activity, clinical response, and treatment needs. Always use the dose prescribed specifically for you.

Esperoct comes as a white to off-white powder in single-dose vials. It is available in nominal dosage strengths of approximately 500, 1,000, 1500, 2,000, 3,000, 4,000, and 5,000 International Units (IU) per vial. The powder must be mixed with the provided sterile sodium chloride solution and is administered through intravenous infusion.

Dosing of Esperoct To Control Bleeding Episodes

Minor bleeding: 40 IU/kg for patients 12 years or older and 65 IU/kg for patients younger than 12 years. A single dose is typically sufficient.

Moderate bleeding: 40 IU/kg for patients 12 years or older and 65 IU/kg for patients younger than 12 years. An additional dose may be given after 24 hours.

Major bleeding: 50 IU/kg for patients 12 years or older and 65 IU/kg for patients younger than 12 years. Additional doses may be given approximately every 24 hours.

Dosing for Surgery

Minor surgery: 50 IU/kg for patients 12 years or older and 65 IU/kg for patients younger than 12 years before surgery. If required, additional doses may be given after 24 hours.

Major surgery: 50 IU/kg for patients 12 years or older and 65 IU/kg for patients younger than 12 years before surgery. Additional doses may be given approximately every 24 hours for the first 7 days and then approximately every 48 hours until wound healing.

Dosing for routine prophylaxis

Patients 12 years or older: The starting dose is 50 IU/kg every 4 days. Dosing frequency may be adjusted based on bleeding episodes.

Patients younger than 12 years: 65 IU/kg twice weekly. Dosing frequency may be adjusted based on bleeding episodes.

Esperoct Side Effects

Common side effects include:
  • Rash or itching
  • Swelling, pain, or redness at the injection site

 

Severe allergic reactions include:
  • Hives
  • Chest tightness
  • Wheezing
  • Dizziness
  • Difficulty breathing
  • Swelling of the face

Seek emergency medical care if you experience any signs of an allergic reaction.

Insurances Accepted

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

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