How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
Alprolix Introduction and Uses
Alprolix injection is a brand-name prescription product. It contains the active ingredient “recombinant coagulation factor IX”, also called eftrenonacog alfa.
This medication belongs to a class known as coagulation factors or hemostatics.
A healthcare provider may prescribe this medication for children and adults with hemophilia B to:
- Control and prevent bleeding episodes
- Prevent bleeding during surgery
- Reduce the frequency of bleeding episodes
In people with hemophilia B, blood doesn’t clot properly, as they have a coagulation factor IX deficiency. Factor IX deficiency causes abnormal bleeding after injuries or surgery. Severe hemophilia B may cause spontaneous joint or muscle bleeds.
Alprolix should not be used to remove inhibitors in people with hemophilia B.
Alprolix Dosing
Alprolix Dosing for Control of Bleeding Episodes
Minor and moderate bleeding: The dose is calculated to achieve a factor IX level of 30% – 60% of normal. May be repeated every 48 hours if there is evidence of bleeding.
Major bleeding: The dose is calculated to achieve a factor IX level of 80% – 100% of normal. May be repeated after 6 – 10 hours, then every 24 hours for 3 days, then every 48 hours until bleeding is resolved.
Alprolix Dosing for Preventing Bleeding During Surgery
Minor surgery: A single infusion to achieve a factor IX level of 50 – 80 IU/dL. Repeat after 24 – 48 hours until bleeding stops.
Major surgery: Initial infusion to achieve a factor IX level of 60 – 100 IU/dL. May be repeated after 6 – 10 hours and then every 24 hours for the first 3 days, then every 48 hours until bleeding stops.
Alprolix Dosing for Routine Prevention of Bleeding Episodes
The typical starting doses are:
- For individuals 12 years or older: 50 IU/kg once weekly or 100 IU/kg every 10 days
- For individuals up to 11 years: 60 IU/kg once weekly
Children younger than 12 years may need more frequent or higher doses. For individuals 12 years or older, dose adjustment is not usually necessary.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
Alprolix Storage and Handling
Before Preparing the Solution
- Store in the original package to prevent exposure to sunlight.
- Maintain storage temperature between 2°C and 8°C (36°F and 46°F). Avoid freezing.
- You may store this medication at room temperature (maximum temperature of 30°C or 86°F) for up to 6 months. The expiration date should be printed on the label.
- If you store this medication at room temperature, record the date when it was removed from refrigeration.
- Once at room temperature, avoid returning the product to the refrigerator.
- Never use Alprolix beyond the expiration date printed on the vial or 6 months after storage at room temperature.
After Preparing the Solution
- You may store the solution at room temperature (maximum temperature 30°C or 86°F) for up to 3 hours. Avoid exposure to direct sunlight.
- Discard the solution if not used within 3 hours after reconstitution.
- Never use a solution that is cloudy or has particulate matter.
- Throw away any unused product.
Alprolix Side Effects
Side effects can be mild or severe.
The most common side effects in previously treated individuals can include:
- Headache
- Tingling or burning in the mouth
- Dizziness
- Fatigue
- Decreased appetite
- Low blood pressure
- Obstructed urine flow
The most common side effects in previously untreated individuals can include:
- Inhibitor (antibody) production
- Pain, redness, or itching at the injection site
- Allergy
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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