How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

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    1. Check Your Coverage/Benefits Verification

    Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

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    2. Transfer Prescription to AmeriPharma®

    We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

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    3. Prior Authorization

    Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

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    4. Copay Assistance & Financial Aid

    We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.

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    5. Nursing Care Coordination If Needed

    AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

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    6. Delivery Coordination

    Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

What Is Adynovate?

Adynovate is a brand-name prescription medication. The active substance in this product is recombinant clotting factor VIII (recombinant antihemophilic factor). It is in a class of medications called antihemophilic factors. The term “recombinant” means this product is made in a lab with recombinant DNA technology instead of being sourced from blood donors. As a result, Adynovate doesn’t have a risk of spreading blood-borne infections.

People with hemophilia A are missing the blood clotting factor called factor VIII. This results in the blood not clotting, leading to a higher risk of unexplained bleeding or, in severe cases, potentially life-threatening internal bleeding.

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How Does Adynovate Work?

This medicine works by replacing the missing clotting factor VIII in children and adults with hemophilia A.

What Is Adynovate Used To Treat?

A healthcare provider may prescribe Adynovate for children and adults with hemophilia A to:

  • Control and prevent bleeding episodes
  • Prevent bleeding during surgery
  • Reduce the frequency of bleeding episodes

This product isn’t used to treat another similar bleeding disorder called von Willebrand disease.

Who Shouldn’t Receive This Medication?

People allergic to recombinant factor VIII, mouse or hamster protein, or any product component shouldn’t use Adynovate. Make sure to tell your healthcare provider about any known allergies you have.

How Adynovate Copay Assistance Works

AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families

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    Advanced software locates funding sources to match you with top-dollar foundation programs

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    One of our copay assistance specialists will assist with the application process

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    Automatic updates will be sent to you and your physician on the status of the funding

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How Is Adynovate Supplied and Used?

This product comes as a sterile, white to off-white powder for reconstitution for intravenous (IV) injection in single-dose vials. One international unit (IU) is equal to the quantity of factor VIII in 1 ml of fresh human plasma. The following strengths are available in the US:

  • 250 IU
  • 500 IU
  • 750 IU
  • 1,000 IU
  • 1,500 IU
  • 2,000 IU
  • 3,000 IU

Before administering the medication, your healthcare provider will determine the dose using a specific formula. Then, they will prepare the liquid for injection following instructions on the package.

The dose and duration of treatment depend on:

  • Body weight
  • Severity of factor VIII deficiency
  • Desired factor VIII level
  • Location and severity of bleeding
  • Condition you’re receiving the infusion for

Adynovate is given as an injection into the veins (IV). It’s typically given twice per week for bleeding prevention and every 8 to 24 hours for bleeding treatment, depending on how severe the bleeding is.

The medication is typically administered over a period of 5 or fewer minutes. The liquid should be used within 3 hours after reconstitution.

Adynovate Side Effects

Common side effects include:
  • Headache
  • Diarrhea
  • Rash
  • Nausea
  • Dizziness
  • Hives
Severe side effects:

Some people receiving Adynovate may experience severe allergic reactions, including anaphylaxis. Anaphylaxis is a potentially fatal reaction that causes difficulty breathing and low blood pressure. Go to the emergency room if you develop the following symptoms after receiving Adynovate:

  • Rash and itching
  • Hoarseness
  • Breathing difficulty
  • Trouble swallowing
  • Swelling of your hands, face, or mouth

Insurances Accepted

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

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