How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
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1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
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2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
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3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
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4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
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5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
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6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Advate?
Advate is a brand-name prescription medication. The active medication in this product is recombinant clotting factor VIII. You may also call it a recombinant antihemophilic factor. It belongs to a class of medicines called antihemophilic factors. The term “recombinant” means Advate is made with recombinant DNA technology.
Recombinant clotting factors are not derived from blood. Therefore, Advate is not a blood product and does not carry the risk of spreading blood-borne viruses.
People with hemophilia A have little or no clotting factor VIII in their blood. Clotting factor VIII helps your body form blood clots. Factor VIII deficiency can lead to spontaneous, uncontrolled internal bleeding, which can be fatal.
The FDA initially approved Advate to control and prevent bleeding episodes in hemophilia A in 2003.
How Does Advate Work?
This medicine works by replacing factor VIII in people with hemophilia A.
What Is Advate Used to Treat?
Advate is used in children and adults with hemophilia A to:
- Control and prevent bleeding episodes
- Prevent bleeding during surgery
- Reduce the frequency of bleeding episodes
This product is not used to treat a form of bleeding disorder called von Willebrand disease.
Who Shouldn’t Receive Advate?
People allergic to mice, hamsters, or any product component should not receive Advate. Inform your provider if you have any known allergies.
How Advate Copay Assistance Works
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
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Advanced software locates funding sources to match you with top-dollar foundation programs
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One of our copay assistance specialists will assist with the application process
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Automatic updates will be sent to you and your physician on the status of the funding
How Is Advate Supplied and Used?
This medicine comes as a white to off-white powder for intravenous infusion (IV) in single-use vials. The following strengths are available in the United States:
- 250 IU
- 500 IU
- 1,000 IU
- 1,500 IU
- 2,000 IU
- 3,000 IU
- 4,000 IU
An IU (International Unit) is the amount of a substance that has a specific biological effect (in this case, to help your blood clot).
Before administering the drug, your provider will determine the dose. The dose and duration of treatment depend on:
- Severity of factor VIII deficiency
- Location and severity of bleeding
- Your body weight and overall health
- Desired factor VIII level
- Condition being treated
Your provider will calculate the dose using specific formulas. Then, they will prepare the liquid for injection following instructions on the package.
Your provider will administer the liquid over a period of 5 or fewer minutes. Before and during administration, you will have your pulse rate measured. If your pulse rate becomes high, they will likely reduce the rate of administration or temporarily stop the injection. Infusion should begin within 3 hours after dilution.
Advate Side Effects
Common side effects include:
- Fever
- Headache
- Cough
- Common cold
- Joint pain
- Vomiting
- Upper airway infection
- Stuffy nose
- Diarrhea
- Sore throat
- Itching
- Unusual taste
- Swelling of legs
- Chills
- Sweating
- Rash
- Fatigue
Severe side effects include:
- Rash and itching
- Hoarseness
- Breathing difficulty
- Trouble swallowing
- Swelling of your hands, face, or mouth
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
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