Dosing Information

The following information describes the recommended doses of Actemra. However, be sure to follow the specific dosing instructions given by your provider because treatment with Actemra is dose-specific for each patient.

For Rheumatoid Arthritis: You can get this medication via subcutaneous injection. If your weight is less than 100 kg, the usual dosage is 162 mg every other week, followed by an increase every week based on clinical response. If your weight is more than 100 kg, the usual dose is 162 mg every week.

For Giant Cell Arteritis: The recommended dose is 6 mg/kg administered through an intravenous (IV) infusion every 4 weeks in combination with a

tapering course of glucocorticoids.

For Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD): Actemra is recommended for adult patients with SSc-ILD at a weekly dose of 162 mg, administered subcutaneously.

For Polyarticular Juvenile Idiopathic Arthritis (PJIA): The subcutaneous PJIA dosage for a child less than 30 kg weight is 162 mg once every 3 weeks. The dosage for a child at or above 30 kg weight is 162 mg once every 2 weeks.

For Systemic Juvenile Idiopathic Arthritis (SJIA): The subcutaneous SJIA dosage for a child less than 30 kg weight is 162 mg once every 2 weeks. The dosage for a child at or above 30 kg weight is 162 mg once every week.

For Cytokine Release Syndrome (CRS): When used for CRS, Actemra is typically administered intravenously. For patients less than 30 kg in weight, the recommended dose is 12 mg/kg in body weight. For patients at or above 30 kg weight, the recommended dose is 8 mg/kg.

For COVID-19: Actemra is recommended for adult COVID-19 patients at a dosage of 8 mg per kg, delivered via intravenous infusion over 60 minutes.