How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

  • 1. Check Your Coverage/Benefits Verification

    Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

  • 2. Transfer Prescription to AmeriPharma®

    We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

  • 3. Prior Authorization

    Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

  • 4. Copay Assistance & Financial Aid

    We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.

  • 5. Nursing Care Coordination If Needed

    AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

  • 6. Delivery Coordination

    Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

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What Is Ziextenzo?

Ziextenzo (generic name: pegfilgrastim-bmez) is a type of medication known as a colony-stimulating factor that is produced by recombinant DNA technology. It stimulates the production, maturation, and activation of neutrophils (a type of white blood cell).

Pegfilgrastim has an advantage over its earlier version, filgrastim, in that it is pegylated, meaning it has undergone a biochemical modification process of bioactive molecules with polyethylene glycol (PEG), which reduces the frequency at which it has to be given to only once per chemotherapy cycle versus multiple doses per chemotherapy cycle with filgrastim.

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What is Ziextenzo Used For?

Ziextenzo is used for the prevention of chemotherapy-induced neutropenia. Neutropenia is a condition where the number of neutrophils in your system becomes low. Neutrophils are a type of white blood cell, and they help your body fight infections, especially ones caused by bacteria.

Having neutropenia increases the risk of a person getting infections, and while most people can fight off infections using conventional treatments (e.g., taking antibiotics prescribed by their doctors), having neutropenia weakens your immune system, making it even more challenging for your body to fight off infections than it would be for a person without neutropenia.

Having neutropenia can also cause a very serious condition called neutropenic sepsis, a whole-body reaction to the infection, which could be potentially life-threatening.

Copay and Financial Assistance

AmeriPharma™ Specialty Pharmacy alleviates financial burdens for patients and their families

  • Advanced software locates funding sources to match you with top-dollar foundation programs

  • One of our copay assistance specialists will assist with the application process

  • Automatic updates will be sent to you and your physician on the status of the funding

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Directions for Use

Ziextenzo comes in a pre-filled syringe form of 6 mg already dissolved in 0.6 ml. It is administered as a subcutaneous injection (given under the skin to either outer upper arms, abdomen [except within 2 inches around the belly button], front middle thigh, or upper outer buttocks) as follows:

6 mg to be injected one time per chemotherapy cycle to be undergone, beginning at least 24 hours after completion of the chemotherapy cycle.

Ziextenzo should not be administered in the period between 14 days before and 24 hours after completion of chemotherapy.

Ziextenzo 6 mg pre-filled syringes should NOT be used for infants, children, or adolescents with a body weight less than 45 kg.

Ziextenzo Side Effects

  • Bone pain
  • Arm or leg pain
  • Increase in white blood cell (WBC) count
  • Antibody development
  • Capillary leak syndrome (a disorder characterized by leakage of plasma from blood vessels into neighboring body cavities and muscles, which could lead to a sharp drop in blood pressure that could be serious if not treated)
  • Inflammation and damage to blood vessels
  • Inflammation of the aorta
  • Sweet’s syndrome (a condition characterized by fever and a painful skin rash that appears mostly on the arms, face and neck)
  • Sickle cell crisis
  • Spleen rupture
  • Spleen enlargement
  • Thrombocytopenia (a condition that occurs when the platelet count in your blood is too low)
  • Hypersensitivity (anaphylaxis)
  • Injection site reaction
  • Inflammation of the tiny filters in the kidneys
  • Acute respiratory distress syndrome (a condition in which fluid collects in the lung’s air sacs, depriving organs of oxygen)
  • Bleeding into the alveolar spaces of the lungs
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Insurances Accepted

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

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Get Started in Minutes

Fill out your information and one of our specialists will call you ASAP.

How Much Can You Save?

Speak with a copay assistance specialist

(877) 778-0318

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