How Assistance Works

Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience

  • 1. Check Your Coverage/Benefits Verification

    Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.

  • 2. Transfer Prescription to AmeriPharma®

    We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.

  • 3. Prior Authorization

    Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.

  • 4. Copay Assistance & Financial Aid

    We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.

  • 5. Nursing Care Coordination If Needed

    AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.

  • 6. Delivery Coordination

    Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.

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What Is Zarxio?

Filgrastim is also known by the brand name Neupogen. Other available biosimilars include Zarxio, Granix, and Nivestym. Neupogen was the first medication produced based on the active element, filgrastim. These drugs have been used successfully for cancer patients to stimulate the growth of white blood cells.

Based on Neupogen, Zarxio became the first biosimilar product available in the United States in March 2015. Thus, Zarxio is similar to Neupogen in its mechanism of action, administration route, strength, and dosage. The difference between the formulation of the two agents is in one inactive component.

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How Is Zarxio Used?

Zarxio has been approved by the Food and Drug Administration (FDA) for the treatment of severe long-standing neutropenia and neutropenia caused by chemotherapy. It has also been approved for use prior to and after a stem cell or bone marrow transplantation, and for patients with acute myeloid leukemia (AML) on induction chemotherapy.

Available Formulations

Zarxio is only available as injections given subcutaneously (under the skin) or intravenously (IV). Zarxio is available as a single-use prefilled syringe for subcutaneous injection in two doses: 300 mcg/0.5 ml and 480 mcg/0.8 ml.

Missed Dose

If you miss a dose, contact your physician immediately to reschedule.

Storage

Store Zarxio in the refrigerator and avoid freezing. If frozen, thaw in the refrigerator before use. Zarxio should be thawed (taken out of the refrigerator) at room temperature for 30 minutes before use. It can be left at room temperature for up to 24 hours. Do not shake the vials and keep them protected from light by storing them in their original containers.

Copay and Financial Assistance

AmeriPharma™ Specialty Pharmacy alleviates financial burdens for patients and their families

  • Advanced software locates funding sources to match you with top-dollar foundation programs

  • One of our copay assistance specialists will assist with the application process

  • Automatic updates will be sent to you and your physician on the status of the funding

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Precautions

Unless approved by your physician, Zarxio is generally not recommended in:

  • Patients who have an allergy to human granulocyte colony-stimulating factors (CFS) such as filgrastim or pegfilgrastim products: Allergic reactions can cause a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate, and sweating. If you have any of these symptoms, stop using Zarxio, and call your doctor or get emergency help right away.
  • Patients with sickle cell disorder: Using Zarxio can lead to a condition called sickle cell crisis, which may be life-threatening.
  • Patients receiving radiation therapy: Zarxio may increase the risk of developing a precancerous condition called myelodysplastic syndrome (MDS) or a type of blood cancer called acute myeloid leukemia (AML).

Pregnancy and Zarxio

Pregnant women, women who are planning to become pregnant, and breastfeeding women must consult a physician prior to initiating Zarxio. The risk to the fetus or baby is unknown.

Zarxio Side Effects

Serious side effects include:
  • Bone and muscle aches
  • Thrombocytopenia, leukocytosis
  • Lung problem called acute respiratory distress syndrome (ARDS)
  • Kidney injury
  • Capillary leak syndrome
  • Inflammation of blood vessels
  • Rupture of the spleen
Less serious side effects include:
  • Dizziness
  • Cough
  • Fatigue
  • Headache
  • Nausea
  • Fever

Insurances Accepted

We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.

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Get Started in Minutes

Fill out your information and one of our specialists will call you ASAP.

How Much Can You Save?

Speak with a copay assistance specialist

(877) 778-0318

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