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How Lumakras Copay Assistance Works
1 – Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
2 – Transfer Prescription to AmeriPharma
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
3 – Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
4 – Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma Specialty Care has secured $55 million in financial assistance for our patients.
5 – Nursing Care Coordination
AmeriPharma puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
6 – Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for immune globulin shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Lumakras?
Lumakras (sotorasib) is a chemotherapy medication used for treating a specific type of non-small cell lung cancer (NSCLC). Providers prescribe Lumakras when NSCLC tumors meet the following conditions:
- Surgical removal of the cancerous part of the lung(s) is not possible or the cancer has spread to other parts of the body (metastatic disease).
- The tumor contains a specific gene called the KRAS-G12C gene, which is confirmed with testing.
- One or more previous chemotherapy treatments have failed to stop the progression of the disease.
How Does Lumakras Work?
All human cells contain a gene that makes a protein called KRAS. This protein works to control and regulate the growth of cells.
If there’s the G12C mutation in the gene that makes KRAS, it results in the gene making the KRAS-G12C protein. This protein can result in cancer because cell growth is no longer properly controlled.
Among all people who have NSCLC, about 13% of people have tumors due to KRAS-G12C. Lumakras works by binding to KRAS-G12C and inactivating it so that it stops signaling cells to grow. In a clinical trial, one-third of the participants saw their tumors shrink by more than 30%. In addition, 2 of the 124 patients saw their tumors disappear.
Copay and Financial Assistance
AmeriPharma Specialty Care alleviates financial burdens for patients and their families
Advanced software locates funding sources to match you with top-dollar foundation programs
One of our copay assistance specialists will assist with the application process
Automatic updates will be sent to you and your physician on the status of the funding
Lumakras Side Effects
The most common side effects reported in people taking Lumakras include:
- Diarrhea (42%)
- Muscle/bone pain (35%)
- Nausea (26%)
- Fatigue (26%)
- Liver damage (25%)
- Cough (20%)
- Vomiting (17%)
- Constipation (16%)
- Shortness of breath (16%)
- Swelling (15%)
- Low appetite (13%)
- Joint pain (12%)
- Pneumonia (12%)
- Rash (12%)
To help with stomach side effects, it is recommended you:
- Eat smaller, more frequent meals
- Avoid dairy products, spicy foods, alcohol, and caffeine
- Avoid fried, greasy, spicy, and sweet foods
- Drink plenty of water and other clear liquids to stay properly hydrated
Lumakras can cause worsening liver function, which can lead to liver failure. Contact your provider if you experience fatigue, weakness, loss of appetite, nausea, abdominal pain, dark urine, yellowing of the skin and eyes (jaundice), and easy bruising or bleeding. These might be signs of liver failure. Your provider will need to order tests to see how your liver is doing.
Lumakras can cause worsening lung function and inflammation. In clinical studies, this happened 2 to 18 weeks after starting the medication. Contact your provider if you experience shortness of breath, cough, or fever.
Lumakras can also cause changes to your blood electrolyte and blood cell count levels. The most common changes are lower white blood cell counts, which can lead to infection, and lower red blood cell counts, which can lead to anemia. In addition, Lumakras can raise protein levels and lower blood calcium and sodium levels. Your provider will likely order blood tests to monitor your electrolyte and blood cell count levels during treatment.
What Is the Recommended Dose for Lumakras?
The typical dose of Lumakras is 960 mg (eight of the 120 mg tablets) by mouth once per day at the same time every day, with or without food. However, since Lumakras has a lot of stomach side effects, taking it with food might help. The medication is continued until your cancer has progressed or you’re no longer able to tolerate the medication. Your provider will adjust your dose down to 240 mg to 480 mg by mouth once per day if you’re experiencing certain side effects.
Swallow Lumakras tablets whole; don’t crush, chew, or split the tablets. If you’re having trouble swallowing tablets, you can place the tablets in 120 ml (4 ounces) of non-carbonated, room-temperature water without crushing the tablets. Don’t use any other liquid. Stir until the tablets are dispersed into small pieces (the tablets will not completely dissolve) and drink immediately or within 2 hours. Make sure to swallow the mixture and don’t chew the pieces of the tablet(s). Rinse the container with an additional 120 ml of water and drink.
People who miss their dose by more than 6 hours should skip that day’s dose and continue taking Lumakras the following day. Don’t double up and take an extra dose to make up for the missed dose. If you experience vomiting after swallowing the Lumakras tablet, don’t take another dose until the next day.