Cómo funciona la asistencia
Optimizando la experiencia de farmacia especializada de nuestros pacientes con una comodidad de servicio completo sin igual
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1. Verifique su cobertura/verificación de beneficios
Nuestro equipo de facturadores expertos encuentra las mejores vías de cobertura que minimizan los costos de bolsillo.
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2. Transferir receta a AmeriPharma®
Procesamos su receta trabajando con su farmacia o prescriptor anterior, haciendo que la transición sea rápida y sencilla.
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3. Autorización previa
Nuestro equipo de especialistas obtiene la aprobación de sus compañías de seguros en un plazo de 24 a 72 horas.
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4. Asistencia para copagos y ayuda financiera
Garantizamos ayuda financiera y reducimos copagos, gastos de bolsillo y deducibles elevados. Hasta la fecha, AmeriPharma® Specialty Care ha obtenido $55 millones en asistencia financiera para nuestros pacientes.
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5. Coordinación de atención de enfermería si es necesario
AmeriPharma® prioriza su agenda y su entorno hogareño al programar y coordinar una de nuestras enfermeras especializadas para sus infusiones en el hogar.
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6. Coordinación de entrega
Los medicamentos se entregan siempre en estricto cumplimiento de los requisitos específicos de envío. Las entregas con cadena de frío al día siguiente y al día siguiente se coordinan según su horario.
Tretten Introduction and Uses
Tretten is a brand-name prescription product. It contains catridecacog, a recombinant form of coagulation factor XIII A-subunit. Tretten belongs to a drug class known as coagulation factors or hemostatics.
Tretten is produced using recombinant DNA technology and is not derived from human plasma.
A healthcare provider may prescribe this medication to prevent bleeding in children and adults with congenital factor XIII (FXIII) A-subunit deficiency.
Congenital factor XIII (FXIII) A-subunit deficiency is a rare inherited bleeding disorder. It is estimated to affect 1 in every 1 to 3 million people. In people with this disorder, the blood doesn’t clot properly, leading to a higher risk of [1]:
- Life-threatening bleeds (most notably, spontaneous bleeding within the brain)
- Cicatrización retardada de heridas
- Recurrent spontaneous abortion in women
Currently, Tretten is the first and only recombinant therapy for people with congenital factor XIII (FXIII) A-subunit deficiency. All other approved treatments are derived from plasma.
This medication shouldn’t be used to treat another similar bleeding disorder called congenital factor XIII B‑subunit deficiency.
Note: Tretten is sold under the brand name NovoThirteen in the EU, Switzerland, and Australia.
Tretten Mechanism of Action
Factor XIII A-subunit plays a crucial role in blood clotting. When bleeding occurs, the body forms a mesh of fibrin proteins to create a blood clot. Activated factor XIII helps strengthen and stabilize the clot by linking fibrin strands together.
When you have factor XIII A-subunit deficiency, blood clots become unstable and fragile. As a result, blood clots may break down too easily, increasing the risk of potentially life-threatening bleeding.
Tretten is a lab-created protein that works the same way as the naturally occurring factor XIII-A subunit in the body. Thus, it helps stabilize clots and prevent bleeding.
Important Tretten Warnings and Precautions
Reacciones alérgicas
This medication may cause allergic reactions. Seek emergency medical care if you experience:
- Erupción
- Opresión en el pecho
- sibilancias
You should not use this medication if you have a history of allergic reactions to this product or any product component.
Producción de inhibidores
In some cases, your body can make proteins called “inhibitors” that can stop this medication from working as well as it should.
If your immune system makes inhibitors, Tretten may become less effective. Your healthcare provider may test for inhibitors if the medication stops working as expected or your factor XIII activity is lower than expected.
Risk of Blood Clots
If you have a higher risk of blood clots, your healthcare provider will monitor you after administering Tretten. Do not use Tretten together with recombinant factor VIIa, as this combination may increase the risk of blood clots.
How Tretten Copay Assistance Works
La farmacia especializada AmeriPharma® alivia las cargas financieras de los pacientes y sus familias.
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Un software avanzado localiza fuentes de financiación para conectarlo con programas de fundaciones de alto valor
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Uno de nuestros especialistas en asistencia de copagos le ayudará con el proceso de solicitud.
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Se le enviarán a usted y a su médico actualizaciones automáticas sobre el estado de la financiación.
Tretten Dosage
The recommended dose of Tretten for routine bleeding prevention is 35 IU/kg of body weight, administered once every 28 days. Your healthcare provider may monitor factor XIII activity and adjust treatment to maintain trough FXIII activity at or above 10%.
Tretten Administration and Proper Use
- Your healthcare provider will inject the reconstituted medicine into your vein once monthly.
- The dose is individualized based on your body weight.
- You may inject it yourself after receiving instructions from your healthcare provider.
- Strictly follow the instructions about proper use, dose, and techniques for administration. If you are unclear about anything, ask your healthcare provider for help.
- Tretten comes as a powder, which must be mixed with sterile water before injection. The sterile water comes in a separate vial.
- If you need a smaller dose, you may dilute the medicine with 0.9% sodium chloride.
- Administer Tretten as a slow intravenous injection at a rate not exceeding 1–2 ml per minute, following your healthcare provider’s instructions.
- Do not mix Tretten with other infusion solutions or administer it as an IV drip.
- Open the package only when you are ready to administer the medicine.
- Don’t use expired or damaged medicine.
Tretten Side Effects
Reacciones alérgicas
Seek emergency medical care if you experience any of the following signs and symptoms after receiving Tretten:
- Dificultad para respirar
- Erupción
- Picor
- Enrojecimiento de la piel
- Desmayo
- Mareo
Coágulos de sangre
Seek emergency medical care if you experience any of the following signs and symptoms after receiving Tretten:
- Pain, swelling, warmth, redness, or a lump in the legs or arms
- Dolor en el pecho
- Sudden severe headache
- Desmayo
Call your doctor immediately if you have any unexpected bleeding.
Otros efectos secundarios pueden incluir:
- Dolor en los brazos o las piernas
- Dolor de cabeza
- Dolor en el lugar de la inyección
- Increased D-dimer levels (a laboratory finding related to blood clot formation and breakdown)
Seguros aceptados
Aceptamos Medicare, Medicaid multiestatal, Medi-Cal, Blue Shield y la mayoría de los seguros privados. Llámenos para obtener más información sobre su cobertura.
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