How Assistance Works
Streamlining our patient’s specialty pharmacy experience with unmatched full-service convenience
-
1. Check Your Coverage/Benefits Verification
Our team of expert billers finds the best avenues of coverage that minimize out-of-pocket costs.
-
2. Transfer Prescription to AmeriPharma®
We process your prescription by working with your previous pharmacy or prescriber, making the transition quick and easy.
-
3. Prior Authorization
Our team of specialists obtains approval from your insurance companies within 24 to 72 hours.
-
4. Copay Assistance & Financial Aid
We secure financial aid and decrease copays, out-of-pocket expenses, and high deductibles. To date, AmeriPharma® Specialty Care has secured $55 million in financial assistance for our patients.
-
5. Nursing Care Coordination If Needed
AmeriPharma® puts your schedule and home environment first when scheduling and coordinating one of our specialized nurses for your in-home infusions.
-
6. Delivery Coordination
Medications are always delivered in strict compliance with the specific requirements for shipping. Next-day and overnight cold-chain deliveries are coordinated around your schedule.
What Is Alymsys?
Alymsys (bevacizumab-maly) is a cancer medicine that inhibits tumor growth by limiting the blood supply that cancer cells need to grow and spread. This cancer-targeted drug is typically prescribed to treat various types of cancer, including brain tumors, colorectal cancer, kidney cancer, and many other forms of cancer.
In 2022, Alymsys was approved in the United States as a biosimilar to Avastin (a branded drug) because it works the same way as Avastin (bevacizumab) but is less expensive than the brand drug.
Alymsys is given as an IV infusion. You may experience high blood pressure, headache, or nosebleed during treatment with Alymsys. Read on to learn its uses, how it works, recommended dosage, possible side effects, and precautionary measures.
Alymsys: FDA-Approved Uses
Alymsys is approved to treat adult patients with any of the following types of cancers:
- Metastatic colorectal cancer
- Persistent, recurrent, or metastatic cervical cancer
- Metastatic or advanced non-small cell lung cancer
- Metastatic renal cell carcinoma (kidney cancer)
- Recurrent glioblastoma (a type of brain tumor)
- Ovarian, fallopian tube, or primary peritoneal cancer
Alymsys can be given alone or together with other anticancer treatments like chemotherapy or immunotherapy.
Alymsys: Working Mechanism
Alymsys (bevacizumab-maly) is a monoclonal antibody and belongs to the vascular endothelial growth factor (VEGF) inhibitor drug class. This monoclonal antibody (bevacizumab-maly) is specifically designed to target and block the VEGF activity.
VEGF is a protein that is released by cancer cells to create new blood vessels within the tumor. These blood vessels provide the tumor with nutrients and oxygen to grow and spread rapidly.
When Alymsys is infused in the body, it blocks the VEGF activity. As a result, tumor growth slows down due to limited blood supply.
Copay and Financial Assistance
AmeriPharma® Specialty Pharmacy alleviates financial burdens for patients and their families
-
Advanced software locates funding sources to match you with top-dollar foundation programs
-
One of our copay assistance specialists will assist with the application process
-
Automatic updates will be sent to you and your physician on the status of the funding
Recommended Dosage
Dosage varies depending on cancer type, treatment regimen, and individual patient factors. Refer to the prescribing information for complete dosing recommendations.
1. Metastatic Colorectal Cancer (mCRC)
The recommended dosage when Alymsys is administered in combination with intravenous fluorouracil-based chemotherapy is:
- 5 mg/kg IV every 2 weeks with bolus-IFL chemotherapy
- 10 mg/kg IV every 2 weeks with FOLFOX4
After progression, patients may receive a dose of 5 mg/kg every 2 weeks or 7.5 mg/kg every 3 weeks.
2. Non-Small Cell Lung Cancer (NSCLC)
For patients with NSCLC, a dose of 15 mg/kg is given intravenously every 3 weeks in combination with carboplatin and paclitaxel.
3. Recurrent Glioblastoma
For patients with recurrent glioblastoma, a dosage of 10 mg/kg is administered intravenously every 2 weeks.
4. Metastatic Renal Cell Carcinoma
The recommended dosage for patients with kidney cancer is 10 mg/kg, given intravenously every 2 weeks in combination with interferon alfa.
5. Persistent, Recurrent, or Metastatic Cervical Cancer
The recommended dosage is 15 mg/kg intravenously every 3 weeks in combination with paclitaxel and cisplatin or in combination with paclitaxel and topotecan.
6. Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
The recommended dosage is 10 mg/kg intravenously every 2 weeks in combination with paclitaxel, pegylated liposomal doxorubicin, or topotecan.
Alymsys Side Effects
Common side effects include:
- High blood pressure (hypertension)
- Headache
- Nose bleeds
- Tiredness or asthenia (weakness)
- Diarrhea and abdominal (belly) pain
- Cold symptoms (i.e., congestion or runny nose, or itching)
- High levels of protein in the urine (proteinuria)
- Dry or watery eyes
- Dry or flaky skin
- Changes in taste
- Peeling or blistering skin
Adverse effects include:
- Gastrointestinal perforation (hole in the gut wall)
- Fistulas (abnormal openings between organs or tissues that may cause drainage, infection, or pain).
- Hemorrhage (bleeding)
- Arterial thromboembolism (blood clots in the arteries)
- Congestive heart failure
- Serious kidney problems
- Poor wound healing
- Ovarian failure
- Coughing or spitting blood
- Confusion, blindness, or any other changes in vision and brain functions
- High fevers or chills
- Hypertensive encephalopathy
- Renal injury
- Embryo-fetal toxicity
- Nephrotic syndrome
- Serious infusion reactions (such as trouble breathing, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting)
Insurances Accepted
We accept Medicare, multi-state Medicaid, Medi-Cal, Blue Shield, and most private insurances. Call us to find out more about your coverage.
Get Started in Minutes
Fill out your information and one of our specialists will call you ASAP.
How Much Can You Save?
Complete this form to save up to 100%!
By submitting, you agree to AmeriPharma’s Terms of Use, Privacy Policy, and Notice of Privacy Practices