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    1. 检查您的保险范围/福利验证

    我们的专业出纳员团队会找到最佳的保险途径,以最大程度地减少自付费用。

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    2. 将处方转移到 AmeriPharma®

    我们与您之前的药房或处方人员合作来处理您的处方,使过渡变得快速而简单。

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    3. 事先授权

    我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。

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    4. 共付额援助和经济援助

    我们确保患者获得经济援助,并降低共付额、自付费用和高额免赔额。迄今为止,AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。

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    5. 必要时的护理协调

    AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时,会将您的日程安排和家庭环境放在首位。

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    6. 交付协调

    药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。

What Is Corifact?

Corifact (also known by its generic name, factor XIII concentrate) is an injectable prescription medicine used to prevent excessive bleeding in people with congenital factor XIII deficiency, which is a rare inherited bleeding disorder. This condition affects around 1 in every 2 to 3 million people, with an incidence in the U.S. of approximately 150 people.

Corifact belongs to the drug class of coagulation factors and is also classified as a hemostatic agent that helps prevent and control bleeding by supporting proper blood clot formation.

This drug was approved by the U.S. Food and Drug Administration (FDA) in 2011 and is available in 12 different countries around the world under the brand name Fibrogammin®- P.

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Corifact Working Mechanism

Corifact contains a purified form of human factor XIII protein extracted from pooled human plasma donated by healthy individuals. It works like the body’s natural clotting protein and replaces the missing factor XIII in the bloodstream. Once infused, it:

  • Increases the level of Factor XIII in the blood
  • Strengthens blood clots
  • Helps clots stay in place long enough for proper healing
  • Reduces the risk of spontaneous or uncontrolled bleeding
  • Helps prevent spontaneous bleeding episodes

By maintaining adequate Factor XIII levels, Corifact helps the body form stronger, more stable clots, lowering the risk of serious bleeding episodes.

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AmeriPharma® 特药药房减轻了患者及其家人的经济负担

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    我们的一位共付额援助专家将协助您完成申请流程

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    自动更新信息将发送给您和您的医生,告知您资金状况

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Dosage for Adults and Children

The dose of Corifact is based on body weight, not age. This means adults and children generally receive the same weight-based dosing schedule.

Routine Preventive Treatment (Prophylaxis)

Both adults and children with congenital Factor XIII deficiency receive a dose of 40 IU/kg body weight intravenously, once every 4 weeks (every 28 days).

The doctor may adjust the dose based on the factor XIII blood levels, bleeding history, or any upcoming surgeries or procedures.

For Perioperative Management of Surgical Bleeding

If you need surgery or experience a bleeding episode, your healthcare provider may adjust the dose based on your Factor XIII levels, the type of surgery, and your clinical response.

Corifact Side Effects

常见的副作用包括:
  • 关节炎症
  • 关节痛
  • Mild rash or itching
  • 头痛
  • 注射部位疼痛
  • Mild fever
  • Elevated thrombin-antithrombin levels
  • Increased blood lactate dehydrogenase
严重的副作用包括:
  • Hypersensitivity or allergic reactions (rash, itching, swelling)
  • Acute ischemia

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我们接受 Medicare、跨州 Medicaid、Medi-Cal、Blue Shield 以及大多数私人保险。请致电我们,了解更多您的保险信息。

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