援助如何运作
通过无与伦比的全方位服务便利性,简化患者的专业药房体验
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1. 检查您的保险范围/福利验证
我们的专业出纳员团队会找到最佳的保险途径,以最大程度地减少自付费用。
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2. 将处方转移到 AmeriPharma®
我们与您之前的药房或处方人员合作来处理您的处方,使过渡变得快速而简单。
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3. 事先授权
我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。
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4. 共付额援助和经济援助
我们确保患者获得经济援助,并降低共付额、自付费用和高额免赔额。迄今为止,AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。
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5. 必要时的护理协调
AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时,会将您的日程安排和家庭环境放在首位。
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6. 交付协调
药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。
What Is Ixifi?
Ixifi (infliximab-qbtx) is an FDA-approved biologic prescription medication made using living cells. It is used to treat certain inflammatory and autoimmune conditions like 类风湿关节炎, Crohn’s disease, and ulcerative colitis.
The FDA first approved Ixifi on December 13, 2017. It was approved as a biosimilar to Remicade (infliximab), meaning it is highly similar to the reference product, with no clinically meaningful differences in safety, purity, or potency. Other infliximab biosimilars include Inflectra 和 Renflexis.
The active ingredient in Ixifi is infliximab. It works by blocking a protein called TNF-alpha, which causes inflammation in your body. Ixifi comes as a 100 mg powder in a single-dose vial that is mixed with liquid before it is given as an intravenous (IV) infusion.
What Is Ixifi Used For?
Ixifi is an FDA-approved medication to treat the following conditions:
克罗恩氏病: In adult patients with moderate to severe active Crohn’s disease, Ixifi can:
- Reduce the signs and symptoms of the disease
- Induce and maintain clinical remission when conventional treatments have not worked well
- Reduce the number of draining enterocutaneous and rectovaginal fistulas
- Help maintain fistula closure in adults with fistulizing Crohn’s disease
Pediatric Crohn’s Disease: Healthcare providers use Ixifi in children 6 years of age and older with moderate to severe active Crohn’s disease. It can reduce signs and symptoms of the disease and induce and maintain clinical remission.
溃疡性结肠炎: Ixifi is used in adults and children 6 years and older with moderate to severe active ulcerative colitis when conventional treatments have not worked well. Ixifi can reduce your symptoms, induce and maintain remission, promote mucosal healing, and help eliminate the need for corticosteroids in adults.
类风湿关节炎: If you have moderate to severe rheumatoid arthritis, you can use Ixifi in combination with methotrexate. It can help reduce the symptoms, slow the progression of structural joint damage, and improve physical function.
强直性脊柱炎: Ixifi can reduce the symptoms in adults with ankylosing spondylitis.
银屑病关节炎: Ixifi is used in adults with psoriatic arthritis. It can improve your symptoms, slow the progression of joint damage, and improve physical function.
斑块状银屑病: Ixifi is used in adults with chronic, severe plaque psoriasis who are candidates for treatment with systemic medications and when other systemic treatment options are medically less appropriate.
Please note that Ixifi does not cure these conditions. Instead, it blocks the activity of TNF-alpha (a protein that promotes inflammation) to control the inflammation responsible for many of the symptoms.
How Ixifi Copay Assistance Works
AmeriPharma® 特药药房减轻了患者及其家人的经济负担
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先进的软件可以定位资金来源,为您匹配高额的基金会项目
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我们的一位共付额援助专家将协助您完成申请流程
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自动更新信息将发送给您和您的医生,告知您资金状况
Dosing of Ixifi
Ixifi comes as a powder that is mixed with liquid before use. You’ll receive it through an intravenous (IV) infusion. The exact dose depends on the condition being treated, your body weight, and how you respond to treatment. Your healthcare provider will determine the right dosage for you. Below are the usual recommended dosages:
克罗恩氏病: For adult patients, the usual initial dose is 5 mg/kg given at week 0, week 2, and week 6. After these initial doses, 5 mg/kg is given every 8 weeks. For those who initially responded to the treatment but later have an inadequate response, the doctor may increase the dose to 10 mg/kg every 8 weeks.
For children aged 6 years and older, the dosage is 5 mg/kg given at week 0, week 2, and week 6, followed by 5 mg/kg every 8 weeks.
溃疡性结肠炎: For adults and children aged 6 years and older, the recommended dose is 5 mg/kg at week 0, week 2, and week 6, followed by 5 mg/kg every 8 weeks.
类风湿关节炎: Ixifi is used in adult patients in combination with methotrexate. The recommended dosage is 3 mg/kg given at week 0, week 2, and week 6, followed by 3 mg/kg every 8 weeks. Some patients may benefit from increasing the dose to up to 10 mg/kg every 8 weeks or receiving treatment as frequently as every 4 weeks, depending on their response.
强直性脊柱炎: The recommended adult dose is 5 mg/kg given at week 0, week 2, and week 6, followed by 5 mg/kg given every 6 weeks.
Psoriatic Arthritis and Plaque Psoriasis: The recommended adult dose is 5 mg/kg given at week 0, week 2, and week 6, followed by 5 mg/kg given every 8 weeks.
Ixifi Side Effects
常见的副作用包括:
- Respiratory infections, such as sinus infections and sore throats
- 头痛
- 咳嗽
- 胃痛
- 输液相关反应
- 病毒感染
严重副作用:
Serious side effects from Ixifi are rare, but they can occur. Here are some serious side effects and warnings associated with Ixifi:
严重感染: Ixifi can increase the risk of serious infections because it suppresses your immune system. These infections can include tuberculosis (TB), bacterial infections, and invasive fungal infections. Ixifi should be discontinued if you develop a serious infection or sepsis.
癌症: Lymphoma and other malignancies, some fatal, have been reported in children and adults treated with TNF blockers, including infliximab products. Your doctor will consider the potential risks and benefits of treatment, particularly if you have risk factors for certain cancers.
心脏衰竭: Ixifi can cause heart failure or make existing heart conditions worse. Tell your doctor if you have symptoms of heart failure, such as shortness of breath, swelling of the ankles or feet, or sudden weight gain.
肝脏问题: In rare cases, Ixifi can cause liver problems. Severe liver injury, including cases resulting in liver transplant or death, has been reported with infliximab products. Contact your doctor if you experience symptoms such as yellowing of the skin or eyes, dark urine, severe fatigue, fever, or pain on the right side of your abdomen.
Severe Allergic and Infusion Reactions: Ixifi can cause serious allergic or infusion reactions during or shortly after the infusion. Symptoms may include difficulty breathing, hives, chest pain, swelling, dizziness, or a significant change in blood pressure.
Please note that this is not a complete list of all possible side effects. Contact your doctor immediately if you experience any severe or unusual symptoms while receiving Ixifi.
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