援助如何运作
通过无与伦比的全方位服务便利性，简化患者的专业药房体验
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1. 检查您的保险范围/福利验证
我们的专业出纳员团队会找到最佳的保险途径，以最大程度地减少自付费用。
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2. 将处方转移到 AmeriPharma®
我们与您之前的药房或处方人员合作来处理您的处方，使过渡变得快速而简单。
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3. 事先授权
我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。
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4. 共付额援助和经济援助
我们确保患者获得经济援助，并降低共付额、自付费用和高额免赔额。迄今为止，AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。
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5. 必要时的护理协调
AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时，会将您的日程安排和家庭环境放在首位。
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6. 交付协调
药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。
What Is Tolcapone?
Tolcapone (pronounced TOLE-ka-pone) is an oral prescription drug sold under the brand name “Tasmar.” It is prescribed to certain adults with Parkinson’s disease who experience movement problems, such as stiffness, tremors, and difficulty moving, when their regular Parkinson’s medications wear off.
Tolcapone (Tasmar) is used as an add-on treatment with levodopa/carbidopa when the effects of these medications wear off between doses, causing Parkinson’s symptoms to return. The U.S. 食品和药物管理局 approved Tolcapone (Tasmar) in 1998.
FDA批准的用途
Tolcapone (Tasmar) is FDA-approved as an adjunct treatment to levodopa/carbidopa for adults with idiopathic Parkinson’s disease who experience motor fluctuations. Because of the risk of serious liver injury, it is generally reserved for patients who have not responded adequately to, or are not appropriate candidates for, other adjunctive therapies.
Tolcapone (Tasmar): Mechanism of Action
Dopamine levels in the brain decline in patients with Parkinson’s disease as the brain cells responsible for producing this neurotransmitter gradually die. As a result, patients gradually lose control over their movements.
When patients take levodopa, a medication that the body converts into dopamine, it increases dopamine levels in the brain and improves movement problems. However, its effects may wear off between doses as the enzyme catechol-O-methyltransferase (COMT) breaks it down, causing symptoms to return.
Tolcapone (Tasmar) helps improve movement and coordination in people with Parkinson’s disease by increasing dopamine levels in the brain. It is taken alongside levodopa to help prolong the effects of the medication. Tolcapone works by blocking an enzyme called COMT, which breaks down levodopa. By slowing this process, more levodopa remains available to reach the brain, helping patients manage Parkinson’s symptoms for longer between doses.
药物剂型
Tolcapone (Tasmar) is available as 100 mg and 200 mg oral tablets and can only be obtained with a doctor’s prescription. This medicine should be stored in tightly closed containers at a controlled room temperature of 20°C to 25°C (68°F to 77°F).
How Tolcapone Copay Assistance Works
AmeriPharma® 特药药房减轻了患者及其家人的经济负担
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先进的软件可以定位资金来源，为您匹配高额的基金会项目
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我们的一位共付额援助专家将协助您完成申请流程
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自动更新信息将发送给您和您的医生，告知您资金状况
剂量和用法
The recommended dosage of Tolcapone (Tasmar) for adults with Parkinson’s disease is 100 mg three times a day. The first dose of tolcapone is taken with your first daily dose of levodopa/carbidopa. The second and third doses of tolcapone are taken 6 and 12 hours later.
In some cases, your doctor may increase the dose to 200 mg three times a day, but only when the additional benefit outweighs the increased risk of liver damage. Tolcapone should generally be discontinued if substantial clinical benefit is not observed within 3 weeks of starting treatment.
Tolcapone must be taken orally (by mouth) with or without food, as prescribed by your doctor. Take the prescribed dose exactly as directed by your doctor.
What to Avoid
Avoid alcohol while taking tolcapone unless your doctor advises otherwise, as it may worsen dizziness or drowsiness. Avoid driving or operating machinery until you know how tolcapone affects you, as it may cause dizziness or sudden sleepiness.
Tolcapone Side Effects
Possible side effects include:
- 恶心
- 食欲不振
- 腹泻
- Uncontrollable movements
- 肌肉痉挛
- 头痛
- 头晕
- 睡眠障碍
- Excessive dreaming
- Somnolence (sleepiness)
- 困惑
- Hallucinations such as seeing things that are not there
- Orthostatic hypotension (dizziness on standing)
- 尿液变色
严重的副作用包括：
Tolcapone carries an FDA boxed warning for severe liver injury, including potentially fatal liver failure. Other serious side effects may include:
- 过敏反应
- Liver injury (common symptoms include persistent nausea, fatigue, lethargy, anorexia, jaundice, dark urine, pruritus, and right upper quadrant tenderness)
If you develop symptoms of an allergic reaction or liver injury, seek medical attention immediately. Your doctor will check your liver function before treatment, every 2 to 4 weeks during the first 6 months, and periodically afterward. Regular monitoring does not completely eliminate the risk of serious liver injury.
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