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    1. 检查您的保险范围/福利验证

    我们的专业出纳员团队会找到最佳的保险途径,以最大程度地减少自付费用。

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    2. 将处方转移到 AmeriPharma®

    我们与您之前的药房或处方人员合作来处理您的处方,使过渡变得快速而简单。

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    3. 事先授权

    我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。

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    4. 共付额援助和经济援助

    我们确保患者获得经济援助,并降低共付额、自付费用和高额免赔额。迄今为止,AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。

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    5. 必要时的护理协调

    AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时,会将您的日程安排和家庭环境放在首位。

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    6. 交付协调

    药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。

What Is Thrombate III?

Thrombate III is an FDA-approved drug used to treat and prevent blood clots in patients with hereditary antithrombin deficiency (hATd), a rare genetic blood-clotting disorder in which a patient has insufficient or dysfunctional antithrombin (AT), a protein that helps prevent excessive blood clotting. 

Hereditary antithrombin deficiency is often undiagnosed and affects around 66,200 people in the United States. 

Thrombate III is also known by its generic name, antithrombin III (human), and is produced from donated human blood plasma.

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Thrombate III: FDA-Approved Uses

Thrombate III (antithrombin III [human]) is approved for use in adults and children with hereditary antithrombin deficiency (hATd) to treat and prevent thromboembolism. Thromboembolism occurs when a blood clot forms, breaks loose, and travels through the bloodstream, potentially blocking another blood vessel.  

Thrombate III can be administered to help prevent thromboembolism before, during, and after surgery (perioperative) and around childbirth (peripartum).

Warning for Patients or Caregivers

Thrombate III is made from donated human blood. Although donated plasma is screened and Thrombate III undergoes manufacturing processes designed to reduce the risk of transmitting infections, a small risk of transmitting viruses or other infectious agents remains. You can talk to your care team if you have questions about the risk of infection.

作用方式

People with hereditary antithrombin deficiency (hATd) have a higher risk of developing an abnormal blood clot during surgery or childbirth due to a lack of sufficient antithrombin (AT) protein. 

Thrombate III temporarily replaces the missing or deficient antithrombin protein, helping regulate blood clotting and reduce the risk of abnormal blood clots.

How Thrombate III Copay Assistance Works

AmeriPharma® 特药药房减轻了患者及其家人的经济负担

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    先进的软件可以定位资金来源,为您匹配高额的基金会项目

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    我们的一位共付额援助专家将协助您完成申请流程

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    自动更新信息将发送给您和您的医生,告知您资金状况

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剂量和用法

The dose of Thrombate III you receive is based on your body weight and the amount of antithrombin in your blood before therapy starts. The Thrombate III regimen involves three phases:

  • Loading dose (first dose): The doctor calculates and administers the first dose to raise the antithrombin activity level to approximately 120% of normal. For example, if the patient’s antithrombin level is 50%, the doctor calculates the dose needed to raise it to 120%.
  • Dose adjustment: After giving the medicine, the doctor checks the patient’s blood to see how much the antithrombin level has increased. The target is to maintain the level between 80% and 120% of normal. If the level is too low or too high, the doctor adjusts the dose as needed.
  • Maintenance dose (follow-up doses): The follow-up dose is initially about 60% of the first dose, usually given every 24 hours. The doctor may change the dose depending on blood test results. The target is still to maintain the level between 80% and 120% of normal.

Thrombate III is administered through an 静脉输液 by a healthcare provider.  It may take 10–20 minutes for the full dose to enter the bloodstream through an IV line.

药物剂型

Thrombate III (antithrombin III [human]) is available in a lyophilized powder form and is supplied as a single-dose vial. Each Thrombate III vial contains approximately 500 IU of antithrombin, which is mixed with 10 ml of sterile water before administration.

Thrombate III Side Effects

常见的副作用包括:
  • 口味改变
  • 胸部不适
  • 发冷或发烧
  • 头晕
  • Muscle pain or cramps
  • 恶心

 

严重的副作用包括:

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