援助如何运作
通过无与伦比的全方位服务便利性，简化患者的专业药房体验
-
1. 检查您的保险范围/福利验证
我们的专业出纳员团队会找到最佳的保险途径，以最大程度地减少自付费用。
-
2. 将处方转移到 AmeriPharma®
我们与您之前的药房或处方人员合作来处理您的处方，使过渡变得快速而简单。
-
3. 事先授权
我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。
-
4. 共付额援助和经济援助
我们确保患者获得经济援助，并降低共付额、自付费用和高额免赔额。迄今为止，AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。
-
5. 必要时的护理协调
AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时，会将您的日程安排和家庭环境放在首位。
-
6. 交付协调
药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。
Recombinate Introduction and Uses
Recombinate is a brand-name prescription product. The active ingredient is a lab-made form of factor VIII, also known as antihemophilic factor, a natural clotting protein found in blood. Recombinate does not contain any human blood products.
Recombinate belongs to the drug class called coagulation factors or hemostatics.
A healthcare provider may prescribe Recombinate for people with hemophilia A to control bleeding episodes or manage bleeding around surgery.
Recombinate is not indicated for the treatment of 血管性血友病 （血管性血友病）。.
Availability note: Takeda has announced the global discontinuation of Recombinate and previously stated that it intended to continue supplying the medication to existing patients until inventory was depleted or expired in mid-2026. Patients currently using Recombinate should speak with their healthcare provider about product availability and whether a transition to another factor VIII therapy is needed.
Recombinate Mechanism of Action
患有血友病 A 的人体内凝血因子 VIII 缺乏或功能异常。因子 VIII 是血液凝固过程所必需的，缺乏因子 VIII 会导致关节、肌肉或内脏器官出现持续性或自发性出血。.
Recombinate works by temporarily replacing the missing clotting factor VIII in the blood, helping the blood form clots and control bleeding.
Before Taking Recombinate
Before using Recombinate, tell your healthcare provider if you:
- Are allergic to Recombinate, any of its ingredients, or mouse, hamster, or bovine proteins
- Have or have previously developed factor VIII inhibitors
- 怀孕或计划怀孕
- 正在哺乳或计划哺乳
Don’t use Recombinate if you have a known hypersensitivity to Recombinate, any of its ingredients, or mouse, hamster, or bovine proteins.
How Recombinate Copay Assistance Works
AmeriPharma® 特药药房减轻了患者及其家人的经济负担
-
先进的软件可以定位资金来源，为您匹配高额的基金会项目
-
我们的一位共付额援助专家将协助您完成申请流程
-
自动更新信息将发送给您和您的医生，告知您资金状况
Recombinate Dosing
您的医疗保健提供者会根据您的体重、您希望增加的VIII因子活性、临床反应和治疗需求来计算您的剂量。请务必使用专门为您开具的剂量。.
Recombinate comes as an off-white to faint yellow powder in single-dose vials. It is available in nominal dosage strengths of approximately 250, 500, 1,000, 1,500, and 2,000 International Units (IU) per vial. The powder must be mixed with an appropriate volume of Sterile Water for Injection before intravenous (IV) infusion. Your provider will use a vial size that is appropriate for your calculated dose.
Dosing for Treatment of Bleeding Episodes
Mild bleeding: The dose is individualized to achieve a post-infusion factor VIII activity level of approximately 20% to 40% of normal. It is administered every 12 to 24 hours for 1 to 3 days until healing is achieved or the bleeding is adequately resolved.
中度出血: The dose is individualized to achieve a post-infusion factor VIII activity level of approximately 30% to 60% of normal. Treatment may be repeated every 12 to 24 hours for 3 days or more until pain or disability is resolved.
危及生命的出血: The dose is individualized to achieve a post-infusion factor VIII activity level of approximately 60% to 100% of normal. Treatment may be repeated every 8 to 24 hours until the threat no longer exists.
Dosing for Surgery
小手术: The dose is individualized to achieve a post-infusion factor VIII activity level of approximately 60% to 80% of normal. According to the prescribing information, a single infusion plus oral antifibrinolytic therapy within 1 hour is sufficient in approximately 70% of cases.
大手术: The dose is individualized to achieve a factor VIII activity level of 80% to 100% of normal (pre- and post-operative). Treatment may be repeated every 8 to 24 hours.
Recombinate Side Effects
常见的副作用包括：
- 发冷
- 冲洗
- 皮疹
- 流鼻血
Other side effects reported during clinical trials included nausea, fatigue, fever, dizziness, itching, pain in an extremity, and low blood pressure.
严重副作用：
Serious risks include severe allergic reactions and the development of factor VIII inhibitors. Contact your healthcare provider right away if bleeding does not stop after using Recombinate, as this may be a sign that the medication is not working as expected. Seek immediate medical care if you develop symptoms of a severe allergic reaction.
接受保险
我们接受 Medicare、跨州 Medicaid、Medi-Cal、Blue Shield 以及大多数私人保险。请致电我们，了解更多您的保险信息。
