援助如何运作
通过无与伦比的全方位服务便利性，简化患者的专业药房体验
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1. 检查您的保险范围/福利验证
我们的专业出纳员团队会找到最佳的保险途径，以最大程度地减少自付费用。
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2. 将处方转移到 AmeriPharma®
我们与您之前的药房或处方人员合作来处理您的处方，使过渡变得快速而简单。
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3. 事先授权
我们的专家团队将在 24 至 72 小时内获得您保险公司的批准。
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4. 共付额援助和经济援助
我们确保患者获得经济援助，并降低共付额、自付费用和高额免赔额。迄今为止，AmeriPharma® 专科护理已为患者争取到 1TP4.4755 亿美元的经济援助。
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5. 必要时的护理协调
AmeriPharma® 在安排和协调我们的专业护士为您进行家庭输液时，会将您的日程安排和家庭环境放在首位。
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6. 交付协调
药品始终严格遵守运输的具体要求。次日或隔夜冷链配送将根据您的时间安排进行协调。
什么是 Mekinist？
Mekinist is a medication used to treat several types of cancer in patients who have one of two specific gene mutations that are called BRAF V600E and BRAF V600K. Mekinist works by inhibiting the MEK1 and MEK2 kinase enzymes’ activity. These enzymes normally promote the cells’ rapid reproduction. Mekinist also activates the BRAF pathway, which inhibits melanoma cell growth.
The generic name of Mekinist is trametinib. It is manufactured by Novartis and was first approved by the FDA in 2013.
Mekinist is currently only available as a brand-name medication, and it comes in oral tablets of 0.5 mg and 2 mg.
What is Mekinist Used For?
Mekinist is FDA approved for the treatment of several cancer types when patients have BRAF V600E or BRAF V600K mutations (the mutations have to be detected by an approved test for Mekinist treatment to be appropriate). Mekinist is used as follows:
- As a single agent: For the treatment of melanoma that cannot be surgically removed or that is metastatic. Mekinist should be used in patients with BRAF V600E or BRAF V600K mutations who have not been treated by a BRAF inhibitor before.
- In combination with Tafinlar (dabrafenib) for:
- Melanoma
- As an adjuvant treatment in patients with BRAF V600E or BRAF V600K mutations and lymph node involvement following complete surgical removal of the melanoma.
- For the treatment of melanoma that cannot be surgically removed or that is metastatic in patients with BRAF V600E mutation.
- 转移性非小细胞肺癌 in patients with BRAF V600E or BRAF V600K mutations.
- Solid tumors that cannot be surgically removed or are metastatic in adult or pediatric patients (at least 6 years old) with BRAF V600E mutation whose tumors have progressed following prior treatment and who have no satisfactory alternative treatment options.
- Anaplastic thyroid cancer that is locally advanced or metastatic in patients with BRAF V600E mutation that have no satisfactory treatment options.
- Melanoma
Mekinist is NOT indicated for the treatment of colorectal cancer as it is known to have a resistance to BRAF inhibition.
共付额和经济援助
AmeriPharma™ 专业药房减轻患者及其家人的经济负担
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先进的软件可以定位资金来源，为您匹配高额的基金会项目
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我们的一位共付额援助专家将协助您完成申请流程
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自动更新信息将发送给您和您的医生，告知您资金状况
How To Take Mekinist
Upon confirmation of BRAF V600E or BRAF V600K mutations, Mekinist is taken as follows (please refer to the indicated use mentioned above for a full diagnosis description):
- Melanoma (as a single agent or in combination with Tafinlar): 2 mg once daily.
- Metastatic non-small cell lung cancer (in combination with Tafinlar): 2 mg once daily.
- Solid tumors that cannot be surgically removed or that are metastatic (in combination with Tafinlar): 2 mg once daily.
- Anaplastic thyroid cancer that is locally advanced or metastatic (in combination with Tafinlar): 2 mg once daily.
Mekinist should be taken at least 1 hour before or 2 hours after a meal. Doses should be taken about 24 hours apart, whether taken as a single agent or in combination with Tafinlar.
Missed doses should NOT be taken within 12 hours of the next dose.
If taken as a combination with Tafinlar, Mekinist should either be taken with the morning or evening dose of Tafinlar.
Mekinist Side Effects
- Edema/swelling (including peripheral edema to the limbs)
- High blood pressure (or worsening of existing high blood pressure)
- Outbreak of acne-like papules and pustules
- 皮疹
- Skin dryness
- Decrease in the serum albumin
- 腹痛
- 腹泻
- 口腔溃疡
- 贫血
- 出血
- Lymphedema (tissue swelling due to accumulation of protein-rich fluid)
- Increase in liver enzymes (ALT, ALP, and AST)
- Slow heart rate
- Bacterial skin infection
- Inflammation of hair follicles
- Infection around the nail
- 瘙痒
- Altered taste
- 口干
- 头晕
- Muscle breakdown (can be damaging to the kidneys)
- 视力模糊
- 眼睛干涩
- 间质性肺疾病
- Inflammation of lung tissue
Mekinist may also cause: Bleeding problems, inflammation or tears to the stomach or intestines, blood clots, heart problems, eye problems, lung or breathing problems, fever, serious skin reactions, and increased blood sugar.
这些并非所有可能发生的副作用。如果您对副作用有任何疑问，请联系您的医生。
接受保险
我们接受 Medicare、跨州 Medicaid、Medi-Cal、Blue Shield 以及大多数私人保险。请致电我们，了解更多您的保险信息。
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