{"id":27652,"date":"2025-07-15T14:40:11","date_gmt":"2025-07-15T21:40:11","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=27652"},"modified":"2025-07-15T14:40:13","modified_gmt":"2025-07-15T21:40:13","slug":"ivig-for-toxic-epidermal-necrolysis-ten","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/","title":{"rendered":"IVIG \u6cbb\u7597\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7 (TEN)"},"content":{"rendered":"<p>\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7 (TEN) \u662f\u4e00\u79cd\u7f55\u89c1\u4f46\u4e25\u91cd\u7684\u76ae\u80a4\u75c5\uff0c\u53ef\u80fd\u5371\u53ca\u751f\u547d\u3002\u5728\u7f8e\u56fd\uff0c\u5927\u7ea6\u6709 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK574530\/\">\u6bcf\u767e\u4e07\u4eba\u53e31.9\u540d\u6210\u5e74\u4eba<\/a> \u6bcf\u5e74\u90fd\u4f1a\u53d1\u751f\u3002\u8fd9\u79cd\u60c5\u51b5\u901a\u5e38\u662f\u7531\u4e8e\u5bf9\u67d0\u4e9b\u836f\u7269\u7684\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94\u800c\u5f15\u8d77\u7684\uff0c\u5bfc\u81f4\u76ae\u80a4\u51fa\u73b0\u76ae\u75b9\u3001\u6e83\u75a1\u548c\u6c34\u75b1\uff0c\u7136\u540e\u8131\u76ae\uff0c\u7c7b\u4f3c\u4e8e\u4e25\u91cd\u70e7\u4f24\u7684\u60c5\u51b5\u3002&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-e049721878ff92f9bb07f55a6bd6ee04\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tIVIG \u6709\u5e2e\u52a9\u5417\uff1f\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\t\u514d\u8d39 IVIG \u6cbb\u7597\u4fe1\u606f\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">\u4e86\u89e3\u66f4\u591a<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig\/\">\u9759\u8109\u6ce8\u5c04\u514d\u75ab\u7403\u86cb\u767d\uff08IVIG\uff09<\/a> \u88ab\u8ba4\u4e3a\u662f <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5130247\/\">\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5<\/a> \u56e0\u4e3a\u5b83\u80fd\u591f\u6291\u5236IV\u578b\u8d85\u654f\u53cd\u5e94\u5e76\u6291\u5236\u7ec6\u80de\u6b7b\u4ea1\u3002\u4e8b\u5b9e\u4e0a\uff0c <a href=\"https:\/\/journals.lww.com\/anti-cancerdrugs\/fulltext\/2022\/01000\/intravenous_immunoglobulin_efficacy_on.96.aspx\">\u8fd1\u671f\u75c5\u4f8b\u62a5\u544a<\/a> \u8bc1\u660e IVIG \u7597\u6cd5\u8054\u5408\u9ad8\u5242\u91cf\u7c7b\u56fa\u9187\u7597\u6cd5\u53ef\u4f7f\u60a3\u8005\u56e0 pembrolizumab \u8bf1\u53d1\u7684 TEN \u5b8c\u5168\u7f13\u89e3\u3002&nbsp;<\/p>\n\n\n\n<p>\u5728\u672c\u6587\u4e2d\uff0c\u6211\u4eec\u5c06\u89e3\u91ca\u4ec0\u4e48\u662f TEN\u3001IVIG \u5982\u4f55\u8d77\u4f5c\u7528\u4ee5\u53ca\u5b83\u5982\u4f55\u5e2e\u52a9\u60a3\u8005\u4ece\u8fd9\u79cd\u53ef\u80fd\u81f4\u547d\u7684\u76ae\u80a4\u75c5\u4e2d\u6062\u590d\u3002<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"\u5207\u6362\u76ee\u5f55\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">\u5207\u6362<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#Toxic_Epidermal_Necrolysis_TEN_Overview\" >\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\uff08TEN\uff09\uff1a\u6982\u8ff0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#What_Causes_Toxic_Epidermal_Necrolysis_TEN\" >\u4ec0\u4e48\u539f\u56e0\u5bfc\u81f4\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\uff08TEN\uff09\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#Efficacy_of_IVIG_Therapy_in_Toxic_Epidermal_Necrolysis_Clinical_Evidence\" >IVIG \u6cbb\u7597\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u7684\u7597\u6548\uff1a\u4e34\u5e8a\u8bc1\u636e<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#How_IVIG_Works_in_Toxic_Epidermal_Necrolysis\" >IVIG \u5728\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u4e2d\u7684\u4f5c\u7528\u673a\u5236<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#1_Blocking_Fas-FasL_Mediated_Apoptosis\" >1. \u963b\u65adFas-FasL\u4ecb\u5bfc\u7684\u7ec6\u80de\u51cb\u4ea1<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#2_Reducing_Cytotoxic_T_Cell_and_NK_Cell_Activity\" >2. \u964d\u4f4e\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u548cNK\u7ec6\u80de\u6d3b\u6027<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#3_Anti-Inflammatory_Effects\" >3.\u6297\u708e\u4f5c\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#4_Modulation_of_Fc_Receptors\" >4. Fc\u53d7\u4f53\u7684\u8c03\u8282<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#5_It_Provides_Passive_Immunity\" >5.\u63d0\u4f9b\u88ab\u52a8\u514d\u75ab<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#When_and_How_Long_Is_IVIG_Therapy_Given_to_TEN_Patients\" >\u4f55\u65f6\u4ee5\u53ca\u591a\u957f\u65f6\u95f4\u5bf9 TEN \u60a3\u8005\u8fdb\u884c IVIG \u6cbb\u7597\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#Are_There_Any_Side_Effects_of_IVIG\" >IVIG \u6709\u526f\u4f5c\u7528\u5417\uff1f&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/ivig\/ivig-for-toxic-epidermal-necrolysis-ten\/#How_Does_Toxic_Epidermal_Necrolysis_Differ_From_SJS\" >\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u4e0e SJS \u6709\u4f55\u4e0d\u540c\uff1f<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\" id=\"h-toxic-epidermal-necrolysis-ten-overview\"><span class=\"ez-toc-section\" id=\"Toxic_Epidermal_Necrolysis_TEN_Overview\"><\/span><strong>\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\uff08TEN\uff09\uff1a\u6982\u8ff0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\uff08TEN\uff09\uff0c\u53c8\u79f0\u83b1\u5c14\u7efc\u5408\u5f81\uff0c\u662f\u53f2\u8482\u6587\u65af-\u7ea6\u7ff0\u900a\u7efc\u5408\u5f81 (SJS) \u4e2d\u7f55\u89c1\u4e14\u6700\u4e25\u91cd\u7684\u4e00\u79cd\u7c7b\u578b\u3002\u5bf9\u4e8e SJS \u60a3\u8005\uff0c\u5f53\u76ae\u80a4\u8868\u9762\u8d85\u8fc7 30% \u7684\u7ec4\u7ec7\u53d7\u635f\uff0c\u4e14\u8eab\u4f53\u6e7f\u6da6\u7684\u5185\u5c42\uff08\u79f0\u4e3a\u7c98\u819c\uff09\u53d7\u5230\u5e7f\u6cdb\u635f\u4f24\u65f6\uff0c\u5373\u53ef\u8bca\u65ad\u4e3a\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7 (TEN)\u3002&nbsp;<\/p>\n\n\n\n<p>\u4e0eSJS\u7c7b\u4f3c\uff0c\u8be5\u75c5\u901a\u5e38\u59cb\u4e8e\u7c7b\u4f3c\u6d41\u611f\u7684\u75c7\u72b6\uff0c\u5728\u670d\u836f\u540e1\u81f33\u5468\u51fa\u73b0\u3002\u968f\u540e\uff0c\u76ae\u80a4\u4e0a\u51fa\u73b0\u75bc\u75db\u7684\u7ea2\u8272\u6216\u7d2b\u8272\u76ae\u75b9\uff0c\u5e76\u8fc5\u901f\u8513\u5ef6\u81f3\u9762\u90e8\u3001\u9888\u90e8\u3001\u8eaf\u5e72\u548c\u8eab\u4f53\u5176\u4ed6\u90e8\u4f4d\uff0c\u4e14\u5448\u4e0d\u89c4\u5219\u5206\u5e03\u3002\u76ae\u75b9\u4f1a\u5f62\u6210\u6c34\u75b1\uff0c\u5927\u9762\u79ef\u76ae\u80a4\u53ef\u80fd\u8131\u843d\uff0c\u9732\u51fa\u76ae\u4e0b\u7cdc\u70c2\u533a\u57df\uff0c\u7c7b\u4f3c\u4e8e\u4e25\u91cd\u7684\u70ed\u6c34\u70eb\u4f24\u3002<\/p>\n\n\n\n<p>\u76ae\u80a4\u548c\u9ecf\u819c\uff08\u4f8b\u5982\u53e3\u8154\u3001\u9f3b\u8154\u3001\u54bd\u5589\u548c\u751f\u6b96\u5668\uff09\u7684\u5e7f\u6cdb\u635f\u4f24\u4f1a\u5bfc\u81f4\u4e25\u91cd\u7684\u4f53\u6db2\u6d41\u5931\u548c\u611f\u67d3\u3002\u5728\u6700\u4e25\u91cd\u7684\u60c5\u51b5\u4e0b\uff0c\u60a3\u8005\u53ef\u80fd\u4f1a\u51fa\u73b0\u4f11\u514b\u3001\u8d25\u8840\u75c7\u3001\u591a\u5668\u5b98\u8870\u7aed\u751a\u81f3\u6b7b\u4ea1\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-causes-toxic-epidermal-necrolysis-ten\"><span class=\"ez-toc-section\" id=\"What_Causes_Toxic_Epidermal_Necrolysis_TEN\"><\/span><strong>\u4ec0\u4e48\u539f\u56e0\u5bfc\u81f4\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\uff08TEN\uff09\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>TEN \u662f\u7531\u7279\u5b9a\u836f\u7269\uff08\u4f8b\u5982\u6297\u751f\u7d20\u3001\u6297\u766b\u75eb\u836f\u3001\u6297\u75db\u98ce\u836f\u3001\u975e\u753e\u4f53\u6297\u708e\u836f\uff09\u5f15\u53d1\u7684\u3002\u5f53\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u5bf9\u67d0\u4e9b\u836f\u7269\u53cd\u5e94\u8fc7\u5ea6\u65f6\uff0c\u5b83\u4f1a\u9519\u8bef\u5730\u5f00\u59cb\u653b\u51fb\u76ae\u80a4\u548c\u9ecf\u819c\u3002\u8fd9\u79cd\u53cd\u5e94\u662f\u4e00\u79cd\u8fdf\u53d1\u578b\u8fc7\u654f\uff08IV \u578b\u8d85\u654f\u53cd\u5e94\uff09\uff0c\u6d89\u53ca\u7279\u6b8a\u7684\u514d\u75ab\u7ec6\u80de\uff0c\u5373\u7ec6\u80de\u6bd2\u6027 T \u7ec6\u80de\u548c\u81ea\u7136\u6740\u4f24 (NK) \u7ec6\u80de\u3002<\/p>\n\n\n\n<p>\u5f53\u8fd9\u4e9b\u7ec6\u80de\u88ab\u6fc0\u6d3b\u65f6\uff0c\u5b83\u4eec\u4f1a\u91ca\u653e\u4e00\u4e9b\u7269\u8d28\uff08\u9897\u7c92\u6eb6\u7d20\u3001\u7a7f\u5b54\u7d20\u548c\u9897\u7c92\u9176\uff09\uff0c\u7834\u574f\u76ae\u80a4\u7684\u5916\u5c42\uff08\u8868\u76ae\uff09\uff0c\u5bfc\u81f4\u76ae\u80a4\u574f\u6b7b\u548c\u8131\u843d\u3002\u8fd9\u79cd\u635f\u4f24\u7684\u4e00\u4e2a\u5173\u952e\u90e8\u5206\u6765\u81ea\u4e8e\u4e00\u79cd\u53eb\u505a <strong><em>Fas\u914d\u4f53<\/em><\/strong>\uff0c\u5b83\u544a\u8bc9\u76ae\u80a4\u7ec6\u80de\uff08\u89d2\u8d28\u5f62\u6210\u7ec6\u80de\uff09\u81ea\u6211\u6bc1\u706d\u3002&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-efficacy-of-ivig-therapy-in-toxic-epidermal-necrolysis-clinical-evidence\"><span class=\"ez-toc-section\" id=\"Efficacy_of_IVIG_Therapy_in_Toxic_Epidermal_Necrolysis_Clinical_Evidence\"><\/span><strong>IVIG \u6cbb\u7597\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u7684\u7597\u6548\uff1a\u4e34\u5e8a\u8bc1\u636e<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u7531\u4e8eTEN\u75be\u75c5\u7f55\u89c1\uff0c\u5173\u4e8eIVIG\u6cbb\u7597TEN\u7684\u6709\u6548\u6027\u7814\u7a76\u6709\u9650\u3002\u7136\u800c\uff0c <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2958184\/\">\u591a\u8d77\u75c5\u4f8b\u62a5\u544a<\/a>\uff1b\u5f00\u653e\u6807\u7b7e\u3001\u524d\u77bb\u6027\u7814\u7a76\uff1b\u4ee5\u53ca\u56de\u987e\u6027\u75c5\u4f8b\u7cfb\u5217\u8868\u660e\uff0c\u5982\u679c\u53ca\u65e9\u5f00\u59cb IVIG \u6cbb\u7597\uff0cTEN \u60a3\u8005\u5c06\u83b7\u5f97\u79ef\u6781\u7684\u7ed3\u679c\u3002&nbsp;<\/p>\n\n\n\n<p>\u4f8b\u5982\uff0c <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2020\/6274053\">\u75c5\u4f8b\u62a5\u544a<\/a> \u4e00\u540d 5 \u5c81\u513f\u7ae5\u56e0\u62c9\u83ab\u4e09\u55ea\u8bf1\u53d1 TEN\uff0c\u63a5\u53d7 IVIG \u6cbb\u7597\u5e76\u7ed3\u5408\u513f\u79d1\u70e7\u4f24\u75c5\u623f\u62a4\u7406\uff0c\u53d6\u5f97\u4e86\u826f\u597d\u7684\u7597\u6548<strong>,<\/strong> \u4e0e\u5355\u72ec\u6cbb\u7597\u76f8\u6bd4\uff0c\u6108\u5408\u901f\u5ea6\u66f4\u5feb\uff0c\u6b7b\u4ea1\u98ce\u9669\u66f4\u4f4e\u3002&nbsp;<\/p>\n\n\n\n<p>\u540c\u6837\u5730\uff0c\u53e6\u4e00\u4e2a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39871376\/\">\u75c5\u4f8b\u62a5\u544a<\/a> \u4e00\u540d83\u5c81\u7684\u7537\u6027\uff0c\u60a3\u6709TEN\uff0c\u5728\u5bf9\u9ad8\u5242\u91cf\u7c7b\u56fa\u9187\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u540e\uff0c\u63a5\u53d7IVIG\uff08400\u6beb\u514b\/\u5343\u514b\/\u5929\uff0c\u6301\u7eed5\u5929\uff09\u6cbb\u7597\uff0c\u76ae\u80a4\u75c7\u72b6\u6709\u6240\u6539\u5584\u3002\u7136\u800c\uff0c\u60a3\u8005\u51fa\u73b0\u4e86\u8840\u5c0f\u677f\u51cf\u5c11\u75c7<strong> <\/strong>\uff08\u8840\u5c0f\u677f\u8ba1\u6570\u4f4e\uff09\uff0cIVIG\u6cbb\u7597\u540e\u75c7\u72b6\u5f97\u5230\u7f13\u89e3\u3002&nbsp;<\/p>\n\n\n\n<p>\u5c3d\u7ba1 IVIG \u663e\u793a\u51fa\u826f\u597d\u7684\u6548\u679c\uff0c\u4f46\u4ecd\u9700\u8981\u4ed4\u7ec6\u76d1\u6d4b\u6f5c\u5728\u7684\u4e0d\u826f\u5f71\u54cd\u3002<\/p>\n\n\n\n<div  id=\"call-to-action-df30ebb5f13dc5872c6d25dd50ebaee0\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\t\u54a8\u8be2 IVIG \u4e13\u5bb6\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-ivig-works-in-toxic-epidermal-necrolysis\"><span class=\"ez-toc-section\" id=\"How_IVIG_Works_in_Toxic_Epidermal_Necrolysis\"><\/span><strong>IVIG \u5728\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u4e2d\u7684\u4f5c\u7528\u673a\u5236<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient.jpg\" alt=\"IVIG nurse with patient\" class=\"wp-image-27654\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-18x12.jpg 18w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/07\/IVIG-nurse-patient-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>IVIG\u7684\u4f5c\u7528\u673a\u5236\u590d\u6742\uff0c\u5c1a\u4e0d\u5b8c\u5168\u6e05\u695a\u3002\u7136\u800c\uff0c\u7814\u7a76\u53d1\u73b0IVIG\u901a\u8fc7\u6291\u5236\u6216\u963b\u65ad\u7279\u5b9a\u7684\u514d\u75ab\u4ecb\u5bfc\u9014\u5f84\u6765\u8c03\u8282\u514d\u75ab\u53cd\u5e94\u3002&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-1-blocking-fas-fasl-mediated-apoptosis\"><span class=\"ez-toc-section\" id=\"1_Blocking_Fas-FasL_Mediated_Apoptosis\"><\/span>1. \u963b\u65adFas-FasL\u4ecb\u5bfc\u7684\u7ec6\u80de\u51cb\u4ea1<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u5728 TEN \u60a3\u8005\u4e2d\uff0cFas-Fas \u914d\u4f53 (FasL) \u901a\u8def\u662f\u5bfc\u81f4\u5927\u9762\u79ef\u76ae\u80a4\u8131\u843d\u548c\u8d77\u6c34\u75b1\u7684\u6838\u5fc3\u673a\u5236<strong>.<\/strong> \u89d2\u8d28\u5f62\u6210\u7ec6\u80de\uff08\u76ae\u80a4\u7ec6\u80de\uff09\u8868\u9762\u6709Fas\u53d7\u4f53\uff0c\u53ef\u4ee5\u4e0e\u514d\u75ab\u7ec6\u80de\u91ca\u653e\u7684Fas\u914d\u4f53\uff08FasL\uff09\u7ed3\u5408\u3002Fas-FasL\u7ed3\u5408\u4f1a\u5f15\u53d1\u76ae\u80a4\u7ec6\u80de\u51cb\u4ea1\uff08\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff09\u3002&nbsp;<\/p>\n\n\n\n<p>\u6297 Fas \u514d\u75ab\u7403\u86cb\u767d\u5b58\u5728\u4e8e <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2958184\/\">IVIG \u963b\u65ad Fas \u53d7\u4f53<\/a> \u901a\u8fc7\u4e0e\u5176\u7ed3\u5408\uff0c\u4ece\u800c\u963b\u6b62 FasL \u9644\u7740\u5728\u76ae\u80a4\u7ec6\u80de\u4e0a\u7684\u53d7\u4f53\u4e0a\u3002<strong> <\/strong>Fas-FasL \u76f8\u4e92\u4f5c\u7528\u7684\u4e2d\u65ad\u4f1a\u963b\u6b62\u7ec6\u80de\u51cb\u4ea1\uff0c\u51cf\u7f13\u6216\u963b\u6b62\u8fdb\u4e00\u6b65\u7684\u76ae\u80a4\u7ec6\u80de\u6b7b\u4ea1\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-2-reducing-cytotoxic-t-cell-and-nk-cell-activity\"><span class=\"ez-toc-section\" id=\"2_Reducing_Cytotoxic_T_Cell_and_NK_Cell_Activity\"><\/span>2. <strong>\u964d\u4f4e\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u548cNK\u7ec6\u80de\u6d3b\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>IVIG \u901a\u8fc7\u4ee5\u4e0b\u65b9\u5f0f\u8c03\u8282\u514d\u75ab\u53cd\u5e94 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5130247\/\">\u4e0b\u8c03\u8fc7\u5ea6\u6d3b\u8dc3\u7684\u7ec6\u80de\u6bd2\u6027 T \u7ec6\u80de\u548c NK \u7ec6\u80de\u7684\u529f\u80fd<\/a>\u3002\u8fd9\u51cf\u5c11\u4e86\u5bfc\u81f4\u7ec4\u7ec7\u635f\u4f24\u7684\u5176\u4ed6\u6709\u5bb3\u5206\u5b50\uff08\u5982\u9897\u7c92\u6eb6\u7d20\u548c\u9897\u7c92\u9176 B\uff09\u7684\u91ca\u653e\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-3-anti-inflammatory-effects\"><span class=\"ez-toc-section\" id=\"3_Anti-Inflammatory_Effects\"><\/span>3.\u6297\u708e\u4f5c\u7528<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>IVIG \u5177\u6709\u6297\u708e\u4f5c\u7528\uff0c\u6709\u52a9\u4e8e\u4e2d\u548c\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u7684\u4f5c\u7528<strong> <\/strong>\u4f8b\u5982<strong> <\/strong>TNF-\u03b1\u3001IL-2 \u548c IFN-\u03b3 \u5728 TEN \u4e2d\u5347\u9ad8\uff0c\u5bfc\u81f4\u708e\u75c7\u548c\u7ec4\u7ec7\u635f\u4f24\u3002&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-4-modulation-of-fc-receptors\"><span class=\"ez-toc-section\" id=\"4_Modulation_of_Fc_Receptors\"><\/span>4. Fc\u53d7\u4f53\u7684\u8c03\u8282<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Fc\u53d7\u4f53\u5728\u514d\u75ab\u6fc0\u6d3b\u4e2d\u53d1\u6325\u4f5c\u7528\u3002IVIG\u6297\u4f53\u4e0e\u514d\u75ab\u6fc0\u6d3b\u7ec6\u80de\uff08\u4f8b\u5982\u5de8\u566c\u7ec6\u80de\u548c\u6811\u7a81\u72b6\u7ec6\u80de\uff09\u4e0a\u7684Fc\u53d7\u4f53\u7ed3\u5408\uff0c\u4ece\u800c <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5130247\/\">\u5e72\u6270\u7ec6\u80de\u6d3b\u5316\u548c\u6297\u539f\u5448\u9012<\/a>. \u8fd9\u53ef\u4ee5\u9632\u6b62\u8fdb\u4e00\u6b65\u7684\u514d\u75ab\u6fc0\u6d3b\u548c\u989d\u5916\u7684\u514d\u75ab\u7ec6\u80de\u88ab\u52df\u96c6\u5230\u76ae\u80a4\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-5-it-provides-passive-immunity\"><span class=\"ez-toc-section\" id=\"5_It_Provides_Passive_Immunity\"><\/span>5. <strong>\u5b83\u63d0\u4f9b\u88ab\u52a8\u514d\u75ab<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u5c3d\u7ba1 IVIG \u5e76\u975e TEN \u7684\u4e3b\u8981\u7528\u9014\uff0c\u4f46\u5b83\u4e5f\u80fd\u63d0\u9ad8\u60a3\u8005\u7684\u6574\u4f53\u6297\u4f53\u6c34\u5e73\uff0c\u5e76\u9632\u6b62\u56e0\u76ae\u80a4\u7f3a\u5931\u800c\u5bfc\u81f4\u7684 TEN \u7ee7\u53d1\u611f\u67d3\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-when-and-how-long-is-ivig-therapy-given-to-ten-patients\"><span class=\"ez-toc-section\" id=\"When_and_How_Long_Is_IVIG_Therapy_Given_to_TEN_Patients\"><\/span><strong>\u4f55\u65f6\u4ee5\u53ca\u591a\u957f\u65f6\u95f4\u5bf9 TEN \u60a3\u8005\u8fdb\u884c IVIG \u6cbb\u7597\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u9759\u8109\u6ce8\u5c04\u514d\u75ab\u7403\u86cb\u767d\uff08IVIG\uff09\u5e94\u5c3d\u65e9\u5f00\u59cb\uff0c\u6700\u597d\u5728\u786e\u8bca\u540e24\u5c0f\u65f6\u5185\u5f00\u59cb\u3002IVIG\u6cbb\u7597\u7684\u6301\u7eed\u65f6\u95f4\u53ef\u80fd\u56e0\u75c5\u60c5\u4e25\u91cd\u7a0b\u5ea6\u800c\u5f02\u3002\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u60a3\u8005\u901a\u5e38\u9700\u8981\u6bcf\u65e5\u63a5\u53d7IVIG\u8f93\u6ce8\uff0c\u6301\u7eed3\u81f35\u5929\u3002<\/p>\n\n\n\n<p>\u60a8\u53ef\u80fd\u4f1a\u63a5\u53d7\u521d\u59cb\u5242\u91cf\u7684 IVIG\uff0c\u6700\u591a <a href=\"https:\/\/www.criteria.blood.gov.au\/MedicalCondition\/View\/2481\">3g\/kg\uff0c\u52063\u5929\u670d\u7528<\/a> \uff081g\/kg\/\u5929\uff09\u6216\u5355\u5242\u91cf\u6700\u9ad8\u53ef\u8fbe 2g\/kg\u3002&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-are-there-any-side-effects-of-ivig-nbsp\"><span class=\"ez-toc-section\" id=\"Are_There_Any_Side_Effects_of_IVIG\"><\/span><strong>IVIG \u6709\u526f\u4f5c\u7528\u5417\uff1f&nbsp;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u60a3\u8005\u5728\u8f93\u6db2\u671f\u95f4\u53ef\u80fd\u4f1a\u51fa\u73b0\u4e00\u4e9b\u526f\u4f5c\u7528\uff0c\u4f8b\u5982\u6076\u5fc3\u3001\u5934\u75db\u3001\u53d1\u51b7\u6216\u53d1\u70e7\u3002\u5728\u6781\u5c11\u6570\u60c5\u51b5\u4e0b\uff0c\u53ef\u80fd\u4f1a\u51fa\u73b0\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08\u8840\u5c0f\u677f\u8ba1\u6570\u4f4e\uff09\u6216\u65e0\u83cc\u6027\u8111\u819c\u708e\uff0c\u9700\u8981\u5bc6\u5207\u76d1\u6d4b\u3002&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-5f863a325016c34f11036dbec9f52a4b\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\t\u83b7\u5f97 IVIG \u4e8b\u5148\u6388\u6743\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">\u5f00\u59cb<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-does-toxic-epidermal-necrolysis-differ-from-sjs\"><span class=\"ez-toc-section\" id=\"How_Does_Toxic_Epidermal_Necrolysis_Differ_From_SJS\"><\/span><strong>\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7\u4e0e SJS \u6709\u4f55\u4e0d\u540c\uff1f<\/strong><span 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