{"id":27550,"date":"2025-06-17T17:02:22","date_gmt":"2025-06-18T00:02:22","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=27550"},"modified":"2025-09-11T10:20:08","modified_gmt":"2025-09-11T17:20:08","slug":"managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/","title":{"rendered":"\u7ba1\u7406\u51fa\u8840\u6027\u75be\u75c5\uff1aWilate \u5982\u4f55\u5e2e\u52a9\u6cbb\u7597\u8840\u7ba1\u6027\u8840\u53cb\u75c5 (VWD) \u548c\u8840\u53cb\u75c5 A"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li>Wilate is a plasma-derived medication containing VWF and FVIII, used to treat VWD and hemophilia A by promoting blood clotting.<\/li>\n\n\n\n<li>It\u2019s safe for repeated use, controls bleeding effectively, and undergoes rigorous viral inactivation to reduce infection risks.<\/li>\n\n\n\n<li>Side effects range from mild (headache, fever) to severe (allergic reactions).<\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-4675803ad7351da7178d3ed1f875828a\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAbout Copay Assistance\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Get Started<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>Bleeding disorders like <a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/von-willebrand-disease-vs-hemophilia-comparing-the-causes-symptoms-diagnosis-and-treatments\/\">von Willebrand disease<\/a> (VWD) and <a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/understanding-hemophilia-and-what-to-expect\/\">hemophilia A<\/a> can make your life difficult. In these conditions, your blood doesn\u2019t clot properly. As a result, you may experience heavy bleeding, even from minor cuts and injuries. <\/p>\n\n\n\n<p>These diseases are not curable. Fortunately, modern medicine has given us several treatment options for patients to manage these conditions and lead active lives. One of them is Wilate. <\/p>\n\n\n\n<p>In this article, we\u2019ll break down everything you need to know about Wilate, including the medication\u2019s side effects, dosing, benefits, and much more.<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#What_Is_Wilate\" >What Is Wilate?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#What_Is_Wilate_Used_To_Treat\" >What Is Wilate Used To Treat?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Von_Willebrand_Disease_VWD\" >Von Willebrand Disease (VWD)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Hemophilia_A\" >Hemophilia A<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#How_Does_Wilate_Work\" >How Does Wilate Work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Benefits_of_Wilate\" >Benefits of Wilate<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Side_Effects_of_Wilate\" >Side Effects of Wilate<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Common_Side_Effects\" >Common Side Effects<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Severe_Side_Effects\" >Severe Side Effects<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Dosing_of_Wilate\" >Dosing of Wilate<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Dosing_for_Von_Willebrand_Disease_VWD\" >Dosing for Von Willebrand Disease (VWD)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#Dosing_for_Hemophilia_A\" >Dosing for Hemophilia A<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#AmeriPharma%C2%AE_Specialty_Your_Partner_in_Bleeding_Disorder_Care\" >AmeriPharma\u00ae Specialty, Your Partner in Bleeding Disorder Care&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/hemophilia\/managing-bleeding-disorders-how-wilate-helps-treat-vwd-and-hemophilia-a\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\" id=\"h-what-is-wilate\"><span class=\"ez-toc-section\" id=\"What_Is_Wilate\"><\/span><strong>What Is Wilate?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Wilate injections (von Willebrand Factor\/Coagulation Factor VIII Complex [Human]) are used to control major and minor bleeding episodes in those with von Willebrand disease (VWD). It is also used in adolescents and adults with hemophilia A for routine prophylaxis (prevent bleeding episodes) and on-demand treatment of bleeding episodes [<a href=\"https:\/\/wilateusa.com\/\">1<\/a>].&nbsp;<\/p>\n\n\n\n<p><a href=\"https:\/\/www.octapharmausa.com\/\">Octapharma<\/a>, a Swiss pharmaceutical company, developed Wilate, and the FDA first approved the drug on December 8, 2009 [<a href=\"https:\/\/www.drugs.com\/history\/wilate.html\">2<\/a>]. Those with VWD have a lack or abnormality of a protein called von Willebrand factor (VWF). People with hemophilia A have a lack or abnormality of a protein called factor VIII (FVIII).&nbsp;<\/p>\n\n\n\n<p>Wilate is a plasma-derived concentrate that contains both von Willebrand factor (VWF) and factor VIII (FVIII). So, by replacing these missing factors, the medication helps with blood clotting in patients with von Willebrand disease (VWD) and hemophilia A.<\/p>\n\n\n\n<p>Unlike some other treatments, Wilate is free of <a href=\"https:\/\/my.clevelandclinic.org\/health\/diagnostics\/22390-albumin-blood-test\">albumin<\/a> (which can cause side effects like allergic reactions). All plasma-derived products carry the risk of virus transmission. To reduce this risk, Wilate undergoes two separate viral inactivation processes [<a href=\"https:\/\/factormyway.com\/html\/pdf\/wilate_PatientBrochure.pdf\">4<\/a>].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-wilate-used-to-treat\"><span class=\"ez-toc-section\" id=\"What_Is_Wilate_Used_To_Treat\"><\/span><strong>What Is Wilate Used To Treat?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Wilate is an FDA-approved medication for treating the following conditions [<a href=\"https:\/\/wilateusa.com\/wp-content\/uploads\/2025\/02\/20241015_pil_18x_USA_50.49.pdf\">3<\/a>]:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Von_Willebrand_Disease_VWD\"><\/span>Von Willebrand Disease (VWD)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>This is a lifelong bleeding disease in which your blood doesn\u2019t clot properly. A protein in our blood called von Willebrand factor helps platelets stick together and form blood clots. <\/p>\n\n\n\n<p>People with von Willebrand disease (VWD) lack enough von Willebrand factor to clot properly. <\/p>\n\n\n\n<p>Wilate is used in children and adults with all types of VWD for on-demand treatment and controlling bleeding episodes. Wilate injections are also used before any surgery to prevent bleeding. Wilate is approved for routine prophylaxis in adults and in children aged 6 years and older with VWD to reduce the frequency of bleeding episodes.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hemophilia_A\"><\/span>Hemophilia A<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>This is a condition in which your blood doesn\u2019t clot properly because you lack a protein called clotting factor VIII (FVIII). <\/p>\n\n\n\n<p>Wilate is used in children and adults with hemophilia A for routine prophylaxis (preventing bleeding episodes) and on-demand <a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/how-to-stop-bleeding-in-hemophilia-patients\/\">treatment of bleeding<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-does-wilate-work\"><span class=\"ez-toc-section\" id=\"How_Does_Wilate_Work\"><\/span><strong>How Does Wilate Work?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Wilate is a human plasma-derived drug that contains a balanced 1:1 ratio of von Willebrand factor (VWF) and factor VIII (FVIII). These are proteins that are critical for blood clotting.<\/p>\n\n\n\n<p>VWF helps the platelets to stick to the site of a blood vessel injury and to each other. This forms the initial blood clot. FVIII works with other clotting proteins to form a stable fibrin clot.<\/p>\n\n\n\n<p>People with von Willebrand disease have a lack of VWF, and people with hemophilia A have a lack of FVIII. Wilate works by replacing both. It helps blood to clot normally and stops or prevents bleeding episodes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-benefits-of-wilate\"><span class=\"ez-toc-section\" id=\"Benefits_of_Wilate\"><\/span><strong>Benefits of Wilate<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Wilate is a medication specially designed to help people with von Willebrand disease (VWD) and <a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/hemophilia-a-vs-b-whats-the-difference\/\">hemophilia A<\/a>. Here are some key advantages of using Wilate [<a href=\"https:\/\/factormyway.com\/html\/pdf\/wilate_PatientBrochure.pdf\">4<\/a>]:<\/p>\n\n\n\n<p><strong>Low Recommended Dosing:<\/strong> Wilate works effectively with a low recommended dose.<\/p>\n\n\n\n<p><strong>Safe for Repeated Use:<\/strong> If you take repeated doses of a VWF\/FVIII product, such as before and after surgery, your FVIII levels can rise temporarily. This is known as FVIII accumulation, which might increase your risk of blood clots. However, clinical trials showed no FVIII accumulation after repeat dosing with Wilate [<a href=\"https:\/\/doi.org\/10.1111\/hae.13106\">5<\/a>], so it is safe for repeated use.<\/p>\n\n\n\n<p><strong>Controls Bleeding Effectively:<\/strong> Wilate can effectively control both major and minor bleeding episodes [<a href=\"https:\/\/doi.org\/10.1111\/hae.13106\">5<\/a>].<\/p>\n\n\n\n<p><strong>Purified for Safety:<\/strong> An advanced purification process is used to make the medication, which helps remove unwanted proteins and impurities.<\/p>\n\n\n\n<p><strong>Double Viral Protection:<\/strong> To reduce the risk of viral transmission and ensure your safety, the drug undergoes two separate viral inactivation processes.<\/p>\n\n\n\n<div  id=\"call-to-action-eeb831ed829a5e49bbdc6e0aa7d4d2d8\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\"> (877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-side-effects-of-wilate\"><span class=\"ez-toc-section\" id=\"Side_Effects_of_Wilate\"><\/span><strong>Side Effects of Wilate<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Like any other medication, Wilate can also have some side effects. These side effects range from mild to severe. Here are some common to severe side effects of Wilate [<a href=\"https:\/\/wilateusa.com\/\">1<\/a>][<a href=\"https:\/\/wilateusa.com\/wp-content\/uploads\/2025\/02\/20241015_pil_18x_USA_50.49.pdf\">3<\/a>]:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\"><span class=\"ez-toc-section\" id=\"Common_Side_Effects\"><\/span><strong>Common Side Effects<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"249\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache.jpg\" alt=\"A woman with a headache holding her temples\" class=\"wp-image-27552\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache-300x178.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache-86x51.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache-167x99.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache-280x166.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/06\/wilate-headache-370x219.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>Some common side effects of Wilate include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Fever<\/li>\n\n\n\n<li>Dizziness<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Hives<\/li>\n\n\n\n<li>Chest discomfort<\/li>\n\n\n\n<li>Wilate injection site reactions (redness, swelling, pain)<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-severe-side-effects\"><span class=\"ez-toc-section\" id=\"Severe_Side_Effects\"><\/span><strong>Severe Side Effects<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>In some cases, Wilate can cause severe side effects. Here are some of the severe side effects of Wilate:<\/p>\n\n\n\n<p><strong>Hypersensitivity Reaction:<\/strong> In rare cases, you may encounter serious allergic reactions to Wilate after taking the drug. Symptoms include rash, itching, shortness of breath, chest tightness, and swelling of the face or throat. Inform your doctor immediately if you experience these symptoms.<\/p>\n\n\n\n<p><strong>Blood Clots:<\/strong> In rare cases, continued treatment with Wilate in patients with VWD can increase the risk of blood clots.<\/p>\n\n\n\n<p><strong>Inhibitor Development:<\/strong> Patients with VWD and hemophilia A may develop antibodies (inhibitors) that make Wilate less effective or ineffective over time. In such cases, you need to consider other treatment options.<\/p>\n\n\n\n<p>This is not a list of all possible side effects. Contact your doctor immediately if you experience any severe side effects of Wilate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing-of-wilate\"><span class=\"ez-toc-section\" id=\"Dosing_of_Wilate\"><\/span><strong>Dosing of Wilate<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>The dosage of Wilate depends on several factors, including your age, weight, disease type, and the severity of your condition. Your doctor will determine the right dosage for you based on your situation. Here are some typical dosing regimens of Wilate [<a href=\"https:\/\/wilateusa.com\/wp-content\/uploads\/2025\/02\/20241015_pil_18x_USA_50.49.pdf\">3<\/a>]:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dosing-for-von-willebrand-disease-vwd\"><span class=\"ez-toc-section\" id=\"Dosing_for_Von_Willebrand_Disease_VWD\"><\/span><strong>Dosing for Von Willebrand Disease (VWD)<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>The dosing varies based on your situation and treatment purpose. The recommended dosage is given below:<\/p>\n\n\n\n<p><strong>For On-Demand Treatment and Control of Bleeding:<\/strong> For minor bleeding, the recommended starting Wilate dosage is 20 to 40 IU of the medication per kg of body weight. After that, a 20 to 30 IU\/kg maintenance dose is usually given every 12 to 24 hours. For major bleeding, the recommended starting dose is 40 to 60 IU\/kg of Wilate injection. Then, to maintain proper clotting levels, doctors usually give 20 to 40 IU\/kg every 12 to 24 hours.<\/p>\n\n\n\n<p><strong>For Surgery:<\/strong> The recommended starting dose of Wilate for minor surgeries (including tooth extractions) is 30 to 60 IU\/kg body weight. After that, a 15 to 30 IU\/kg maintenance dose is given every 12 to 24 hours for up to 3 days. For major surgeries, the starting dose of Wilate is 40 to 60 IU\/kg, and the drug\u2019s maintenance dose is 20 to 40 IU\/kg every 12 to 24 hours for up to 6 days or more.<\/p>\n\n\n\n<div  id=\"call-to-action-8f836fe5f20365b3309a925435634b28\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Copay Assistance Now\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Learn More<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dosing-for-hemophilia-a\"><span class=\"ez-toc-section\" id=\"Dosing_for_Hemophilia_A\"><\/span><strong>Dosing for Hemophilia A<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>The recommended dosage of Wilate for hemophilia A is given below:<br><br><strong>For Routine Prophylaxis:<\/strong> To prevent bleeding episodes in adolescents and adults, the usual dose of the medication is 20 to 40 IU\/kg of Wilate every 2 to 3 days.<\/p>\n\n\n\n<p><strong>For On-Demand Treatment of Bleeding Episodes:<\/strong> If you start bleeding, you can use Wilate to stop it. The dosage depends on how severe your bleeding is.&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>For minor bleeding, the recommended dose is 30 to 40 IU\/kg, repeated every 12 to 24 hours until the bleeding stops.&nbsp;<\/li>\n\n\n\n<li>For moderate bleeding, the recommended dose is 30 to 40 IU\/kg. You have to repeat it every 12 to 24 hours for 3 to 4 days or more until the bleeding stops.&nbsp;<\/li>\n\n\n\n<li>For major bleeding, the dose is 35 to 50 IU\/kg body weight, repeated every 12 to 24 hours. You have to continue this dose for 3 to 4 days or more, depending on the severity.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"AmeriPharma%C2%AE_Specialty_Your_Partner_in_Bleeding_Disorder_Care\"><\/span>AmeriPharma\u00ae Specialty, Your Partner in Bleeding Disorder Care&nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>If you are suffering from a bleeding disorder such as VWD or hemophilia A, you can rely on <a href=\"https:\/\/ameripharmaspecialty.com\/about-us\/\">AmeriPharma\u00ae Specialty Pharmacy<\/a> for access to specialty medications like Wilate.<\/p>\n\n\n\n<p>Our LegitScript-certified <a href=\"https:\/\/ameripharmaspecialty.com\/\">specialty pharmacy<\/a> provides hard-to-find medications for complex conditions to individuals in over 40 U.S. states and territories.\u00a0<\/p>\n\n\n\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/book-a-call\/\">Book a call<\/a> with us today to learn more about Wilate and its cost. Start receiving specialty care at home with full-service coordination, <a href=\"https:\/\/ameripharmaspecialty.com\/financial-assistance\/\">copay assistance<\/a>, and 24\/7\/365 support.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-faqs\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span><strong>FAQs<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Here are some frequently asked questions about Wilate:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-1-how-is-wilate-different-from-other-clotting-factor-products\"><strong>1. 1. How is Wilate different from other clotting factor medications?<\/strong><\/h4>\n\n\n\n<p>Wilate is the first VWF\/FVIII drug developed especially for von Willebrand disease (VWD) (per Octapharma and initial FDA approval data). It is made from human plasma and contains both von Willebrand factor (VWF) and factor VIII (FVIII) in a balanced 1:1 ratio. It is double virus-inactivated and does not contain albumin, making it a safe and effective option [<a href=\"https:\/\/wilateusa.com\/wp-content\/uploads\/2025\/02\/20241015_pil_18x_USA_50.49.pdf\">3<\/a>][<a href=\"https:\/\/wilateusa.com\/vwd\/faqs\/\">6<\/a>].<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-2-can-i-use-wilate-at-home\"><strong>2. Can I use Wilate at home?<\/strong><\/h4>\n\n\n\n<p>Yes. Home administration of Wilate injections is possible, which is convenient and time-saving. But first, you or your caregiver has to undergo training by a healthcare provider.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-3-can-i-use-wilate-during-pregnancy-or-breastfeeding\"><strong>3. Can I use Wilate during pregnancy or breastfeeding?<\/strong><\/h4>\n\n\n\n<p>There is still no data available to recommend or limit the use of Wilate for hemophilia A or VWD during pregnancy and breastfeeding [<a href=\"https:\/\/wilateusa.com\/wp-content\/uploads\/2025\/02\/20241015_pil_18x_USA_50.49.pdf\">3<\/a>]. Your doctor will weigh the benefits and risks before prescribing it during pregnancy or breastfeeding.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-4-what-if-i-experience-side-effects-after-using-wilate\"><strong>4. What if I experience side effects after using Wilate?<\/strong><\/h4>\n\n\n\n<p>If you have mild side effects like a headache or nausea, they may go away on their own. But if you experience allergic reactions (rash, swelling, trouble breathing) or signs of a serious problem like blood clots, contact your doctor or seek emergency care immediately.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8840\u7ba1\u6027\u8840\u53cb\u75c5 (VWD) \u548c\u7532\u578b\u8840\u53cb\u75c5\u7b49\u51fa\u8840\u6027\u75be\u75c5\u4f1a\u7ed9\u60a8\u7684\u751f\u6d3b\u5e26\u6765\u8bf8\u591a\u4e0d\u4fbf\u3002\u5728\u8fd9\u4e9b\u60c5\u51b5\u4e0b\uff0c\u60a8\u7684\u8840\u6db2\u65e0\u6cd5\u6b63\u5e38\u51dd\u7ed3\u3002\u56e0\u6b64\uff0c\u5373\u4f7f\u662f\u8f7b\u5fae\u7684\u5272\u4f24\u548c\u635f\u4f24\uff0c\u4e5f\u53ef\u80fd\u5bfc\u81f4\u5927\u91cf\u51fa\u8840\u3002<\/p>","protected":false},"author":25,"featured_media":27551,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[6,4],"tags":[31],"class_list":["post-27550","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hemophilia","category-other-health-conditions","tag-dr-mark-alfonso"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Understanding How Wilate Helps Treat VWD and Hemophilia A<\/title>\n<meta name=\"description\" content=\"Understand how Wilate helps patients manage bleeding disorders like VWD and hemophilia A. 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Mark Alfonso, PharmD, BCMTMS","author_link":"https:\/\/ameripharmaspecialty.com\/zh\/author\/mark-alfonso\/"},"uagb_comment_info":0,"uagb_excerpt":"Bleeding disorders like von Willebrand disease (VWD) and hemophilia A can make your life difficult. 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