{"id":23815,"date":"2024-01-19T11:57:06","date_gmt":"2024-01-19T19:57:06","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/understanding-myasthenic-crises-what-you-need-to-know-2\/"},"modified":"2024-07-09T15:28:31","modified_gmt":"2024-07-09T22:28:31","slug":"understanding-myasthenic-crises-what-you-need-to-know","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/","title":{"rendered":"\u4e86\u89e3\u91cd\u75c7\u808c\u65e0\u529b\u5371\u8c61\uff1a\u4f60\u9700\u8981\u77e5\u9053\u4ec0\u4e48"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Not everyone with myasthenia gravis (MG) develops a myasthenic crisis. However, when it occurs, it can be life-threatening. This article discusses the symptoms, causes, precipitating factors, diagnosis, and treatment of myasthenic crises.<\/span><\/p>\n\n\n<div  id=\"call-to-action-178d9186a534bc0d8d64891d15b1676b\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist About Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/myasthenia-gravis\/myasthenia-gravis\/\"><span style=\"font-weight: 400;\">Myasthenia gravis<\/span><\/a><span style=\"font-weight: 400;\"> is an autoimmune problem that causes muscle weakness throughout your body.\u00a0 Myasthenic crisis (MC) is when your breathing muscles become very weak, often requiring a breathing machine (ventilator) to help you breathe. Myasthenic crisis is the most severe complication of myasthenia gravis. MC can also weaken the muscles you use to swallow [<\/span><a href=\"https:\/\/jneuroinflammation.biomedcentral.com\/articles\/10.1186\/s12974-022-02448-4\"><span style=\"font-weight: 400;\">1<\/span><\/a><span style=\"font-weight: 400;\">]. This means you might need to be fed through another method, like a nasogastric tube or <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/tpn-total-parenteral-nutrition\/\"><span style=\"font-weight: 400;\">parenteral nutrition<\/span><\/a><span style=\"font-weight: 400;\">. MC affects 15% to 20% of people with MG and typically occurs during the first few years following an MG diagnosis. Nearly 1 in 3 MC survivors may experience another episode [<\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/mus.27832\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">].<\/span><br \/>\u00a0<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#What_Causes_a_Myasthenic_Crisis\" >What Causes a Myasthenic Crisis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Symptoms_Things_To_Look_Out_For\" >Symptoms: Things To Look Out For<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Diagnosis\" >Diagnosis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Myasthenic_Crisis_Treatment\" >Myasthenic Crisis Treatment<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Breathing_support\" >Breathing support<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Medications_and_therapies\" >Medications and therapies<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Prognosis\" >Prognosis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Tips_to_Prevent_a_Myasthenic_Crisis\" >Tips to Prevent a Myasthenic Crisis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/#Myasthenic_Crisis_FAQs\" >Myasthenic Crisis: FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_Causes_a_Myasthenic_Crisis\"><\/span>What Causes a Myasthenic Crisis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In half of the cases, the exact cause is unclear.\u00a0\u00a0<\/span><br \/><span style=\"font-weight: 400;\">Respiratory infections are a common trigger. Other precipitating factors can include [<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3726100\/#https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3726100\/#\"><span style=\"font-weight: 400;\">3<\/span><\/a><span style=\"font-weight: 400;\">]:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Physical or emotional stressors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skipping your myasthenia gravis medication<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tapering off drugs that regulate your immune function<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medications like antibiotics, antiseizure drugs, steroids, or antiarrhythmic agents<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Childbirth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Premenstrual syndrome (PMS)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleep deprivation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Surgery<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A tumor that develops in your thymus<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Environmental factors like extremely hot or cold weather<\/span><\/li>\n<\/ul>\n<p>\u00a0<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Symptoms_Things_To_Look_Out_For\"><\/span>Symptoms: Things To Look Out For<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Though called a \u201ccrisis,\u201d a myasthenic crisis typically develops slowly, and a sudden episode is rare. Call your provider immediately if you have the symptoms suggestive of an MC. If you can\u2019t get a hold of your provider, it\u2019s recommended to go to an emergency room to get tested.<\/span><br \/><span style=\"font-weight: 400;\">Symptoms of MC include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shallow breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing\/speaking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty swallowing\/chewing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness of your jaw or tongue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal tone<\/span><\/li>\n<\/ul>\n<p>\u00a0<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Diagnosis\"><\/span>Diagnosis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-23818 size-full\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/01\/ctscan.jpg\" alt=\"Female Doctor Looking At Patient Undergoing CT Scan\" width=\"419\" height=\"279\" \/>When you visit your provider for a possible crisis, they will first perform a physical exam and review your medical history. Then, they will give you tests to rule out other heart and lung problems that can cause similar symptoms. The tests can include:<\/span><\/p>\n<ul>\n<li><b>Blood gases, <\/b><span style=\"font-weight: 400;\">which help determine the amount of oxygen and carbon dioxide in your blood.\u00a0<\/span><\/li>\n<li><b>Chest X-rays, <\/b><span style=\"font-weight: 400;\">which provide visualizations of your lungs and heart, allowing your doctor to identify signs of an infection.\u00a0<\/span><\/li>\n<li aria-level=\"1\"><b>CT scans, <\/b><span style=\"font-weight: 400;\">which help your doctor check your lungs, heart, and blood vessels.<\/span><\/li>\n<li aria-level=\"1\"><b>MRIs, <\/b><span style=\"font-weight: 400;\">which are generally used to check if you have an enlarged thymus.\u00a0<\/span><\/li>\n<li aria-level=\"1\"><b>Pulmonary function tests (PFT), <\/b><span style=\"font-weight: 400;\">which are used to measure how much air you inhale and exhale over a specific amount of time.\u00a0<\/span><\/li>\n<\/ul>\n<p>\u00a0<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Myasthenic_Crisis_Treatment\"><\/span>Myasthenic Crisis Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">A myasthenic crisis is a medical emergency that needs treatment at a hospital.<\/span><br \/><span style=\"font-weight: 400;\">Treatment aims to strengthen your breathing muscles and treat the cause. You\u2019ll also be started on appropriate medication to prevent further complications.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Breathing_support\"><\/span><span style=\"font-weight: 400;\">Breathing support<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Depending on how severe your breathing difficulty is, your provider may insert a tube into your windpipe (intubation) to make it easier to breathe. The tube, which is connected to a ventilator, helps you breathe in and out more easily. Intubation can last 2 weeks or longer, depending on how your breathing and muscle strength improve.\u00a0<\/span><br \/><span style=\"font-weight: 400;\">Alternatively, a bilevel positive airway pressure (BiPAP) device may be used. BiPAP is a type of ventilator that uses a face mask to help air move in and out of your lungs.\u00a0<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Medications_and_therapies\"><\/span><span style=\"font-weight: 400;\">Medications and therapies<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/\"><span style=\"font-weight: 400;\">IVIG<\/span><\/a><span style=\"font-weight: 400;\"> or plasmapheresis (plasma exchange, or PE) is often considered as the first-line therapy. Both IVIG and PE are highly effective, producing significant improvements in approximately 70% of all cases.\u00a0<\/span><br \/><span style=\"font-weight: 400;\">Moreover, your provider may give you medicines to suppress your immune system and improve muscle strength. You may also need IV fluids to prevent low blood pressure.\u00a0<\/span><br \/>\u00a0<\/p>\n\n\n<div  id=\"call-to-action-de98880961610242baaf3e58c4a1e4f4\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tCan IVIG help?\u00a0|\u00a0Free IVIG Treatment Info\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Prognosis\"><\/span>Prognosis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Deaths due to MC have decreased dramatically in the last few decades, thanks to effective treatments like IVIG and plasmapheresis. The death rate in the US is below 5%, and MC is unlikely to affect the long-term prognosis of myasthenia gravis [<\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/mus.27832\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">].<\/span><br \/>\n&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Tips_to_Prevent_a_Myasthenic_Crisis\"><\/span>Tips to Prevent a Myasthenic Crisis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following steps can lower the risk of having a myasthenic crisis:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take your myasthenia gravis medications as directed.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Take your medications about 30 minutes before meals to keep food from getting into your airways.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eat a nutritious diet for optimal body weight and muscle strength.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoid direct contact with people who have respiratory infections like a cold or flu.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Get enough daily sleep.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Manage stress effectively.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Myasthenic_Crisis_FAQs\"><\/span>Myasthenic Crisis: FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h4><span style=\"font-weight: 400;\">What is the difference between a myasthenic crisis and a cholinergic crisis?<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Myasthenic crisis is a complication of myasthenia gravis. It occurs when your breathing muscles become very weak. On the other hand, a cholinergic crisis happens when you take a high dose of your myasthenia gravis medicines.\u00a0<\/span><\/p>\n<h4><span style=\"font-weight: 400;\">What is a clinical feature of a myasthenic crisis?<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Difficult or labored breathing is the most prominent clinical feature.\u00a0<\/span><\/p>\n<h4><span style=\"font-weight: 400;\">Myasthenic crisis vs myasthenia gravis flares: Are they the same?<\/span><\/h4>\n<p><span style=\"font-weight: 400;\">Myasthenia gravis flares and a myasthenic crisis are different. While the flares usually cause double vision and unsteadiness, a myasthenic crisis primarily causes breathing difficulties.\u00a0<\/span><br \/>\n&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5e76\u975e\u6240\u6709\u91cd\u75c7\u808c\u65e0\u529b (MG) \u60a3\u8005\u90fd\u4f1a\u51fa\u73b0\u808c\u65e0\u529b\u5371\u8c61\u3002\u7136\u800c\uff0c\u4e00\u65e6\u53d1\u751f\uff0c\u53ef\u80fd\u5371\u53ca\u751f\u547d\u3002\u672c\u6587\u63a2\u8ba8\u808c\u65e0\u529b\u5371\u8c61\u7684\u75c7\u72b6\u3001\u75c5\u56e0\u3001\u8bf1\u53d1\u56e0\u7d20\u3001\u8bca\u65ad\u548c\u6cbb\u7597\u3002<\/p>","protected":false},"author":26,"featured_media":23817,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[10],"tags":[32],"class_list":["post-23815","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-myasthenia-gravis","tag-dr-robert-hakim"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Understanding Myasthenic Crises: What You Need to Know<\/title>\n<meta name=\"description\" content=\"This article is about a myasthenic crisis, which can occur in people with myasthenia gravis. Topics include causes, treatments, and more.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/myasthenia-gravis\/understanding-myasthenic-crises-what-you-need-to-know\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Understanding Myasthenic Crises: What You Need to Know\" \/>\n<meta property=\"og:description\" content=\"This article is about a myasthenic crisis, which can occur in people with myasthenia gravis. 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