{"id":22936,"date":"2023-06-23T12:40:04","date_gmt":"2023-06-23T19:40:04","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=22936"},"modified":"2026-03-19T14:45:21","modified_gmt":"2026-03-19T21:45:21","slug":"otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/","title":{"rendered":"Otezla\uff1a\u6cbb\u7597\u6591\u5757\u578b\u94f6\u5c51\u75c5\u548c\u94f6\u5c51\u75c5\u5173\u8282\u708e\u7684\u6709\u6548\u975e\u751f\u7269\u7597\u6cd5"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">\u5bf9\u4e8e\u6591\u5757\u6027\u94f6\u5c51\u75c5\u60a3\u8005\uff0c\u4e73\u818f\u6216\u8f6f\u818f\u7b49\u5c40\u90e8\u6cbb\u7597\u6709\u65f6\u6548\u679c\u4e0d\u4f73\u3002\u6591\u5757\u6027\u94f6\u5c51\u75c5\u662f\u4e00\u79cd\u7ec8\u8eab\u75be\u75c5\uff0c\u53cd\u590d\u53d1\u4f5c\u548c\u7f13\u89e3\u3002\u8bb8\u591a\u6591\u5757\u6027\u94f6\u5c51\u75c5\u60a3\u8005\u8fd8\u53ef\u80fd\u53d1\u5c55\u4e3a\u94f6\u5c51\u75c5\u5173\u8282\u708e\uff0c\u5bfc\u81f4\u5173\u8282\u5468\u56f4\u75bc\u75db\u3001\u80bf\u80c0\u548c\u708e\u75c7\u3002&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">2014 \u5e74\uff0c\u4e00\u79cd\u540d\u4e3a Otezla \u7684\u836f\u7269\u83b7\u5f97 <a href=\"https:\/\/www.fda.gov\/\">\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40<\/a> (FDA) \u7528\u4e8e\u6cbb\u7597\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u548c\u94f6\u5c51\u75c5\u5173\u8282\u708e\u30022019\u5e74\uff0cOtezla \u83b7\u5f97 FDA \u989d\u5916\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u767d\u585e\u6c0f\u75c5\u3002\u767d\u585e\u6c0f\u75c5\u662f\u4e00\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u53ef\u5bfc\u81f4\u53e3\u8154\u6e83\u75a1\u3001\u751f\u6b96\u5668\u6e83\u75a1\u548c\u8eab\u4f53\u67d0\u4e9b\u90e8\u4f4d\u7684\u708e\u75c7\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5728\u672c\u6587\u4e2d\uff0c\u6211\u4eec\u5c06\u63a2\u8ba8 Otezla \u7684\u4f5c\u7528\u673a\u5236\u3001\u529f\u6548\u548c\u5b89\u5168\u6027\uff0c\u4ee5\u53ca\u5176\u6f5c\u5728\u7684\u526f\u4f5c\u7528\u3001\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u548c\u60a3\u8005\u6ce8\u610f\u4e8b\u9879\u3002<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"\u5207\u6362\u76ee\u5f55\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">\u5207\u6362<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#What_Is_Otezla\" >\u4ec0\u4e48\u662f Otezla\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#What_Is_Otezla_Used_For\" >Otezla \u7684\u7528\u9014\u662f\u4ec0\u4e48\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#How_Is_Otezla_Used\" >Otezla\u5982\u4f55\u4f7f\u7528\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#How_Does_It_Work\" >\u5b83\u662f\u5982\u4f55\u5de5\u4f5c\u7684\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Side_Effects\" >\u526f\u4f5c\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Drug_Dosage\" >\u836f\u7269\u5242\u91cf<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Precautions\" >\u9632\u8303\u63aa\u65bd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Cost\" >\u6210\u672c<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Otezla\"><\/span>\u4ec0\u4e48\u662f Otezla\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u662f\u7ecf FDA \u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u3001\u94f6\u5c51\u75c5\u5173\u8282\u708e\u548c\u4e0e\u767d\u585e\u6c0f\u75c5\u76f8\u5173\u7684\u53e3\u8154\u6e83\u75a1\u7684\u5904\u65b9\u836f\u3002&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5b83\u5c5e\u4e8e\u78f7\u9178\u4e8c\u916f\u9176-4 (PDE4) \u6291\u5236\u5242\u7c7b\u836f\u7269\uff0c\u901a\u8fc7\u6291\u5236\u4f53\u5185\u708e\u75c7\u53d1\u6325\u4f5c\u7528\u3002Otezla \u662f <\/span><a href=\"https:\/\/www.healthline.com\/health\/drugs\/generic-vs-brand#generic-drugs\"><span style=\"font-weight: 400;\">\u4eff\u5236\u836f<\/span><\/a><span style=\"font-weight: 400;\">\uff0c\u963f\u666e\u65af\u7279\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u81ea <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4665061\/\"><span style=\"font-weight: 400;\">2014\u5e74\u6279\u51c6<\/span><\/a><span style=\"font-weight: 400;\">Otezla \u4f5c\u4e3a\u4e00\u79cd\u5b89\u5168\u6709\u6548\u7684\u6cbb\u7597\u94f6\u5c51\u75c5\u5173\u8282\u708e\u3001\u5404\u671f\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u4ee5\u53ca\u4e0e\u767d\u585e\u6c0f\u75c5\u76f8\u5173\u7684\u53e3\u8154\u6e83\u75a1\u7684\u65b9\u6cd5\uff0c\u5df2\u5728\u60a3\u8005\u548c\u533b\u7597\u4fdd\u5065\u4e13\u4e1a\u4eba\u58eb\u4e2d\u5e7f\u53d7\u6b22\u8fce\u3002&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u7684\u4e3b\u8981\u4f18\u52bf\u4e4b\u4e00\u662f\u5b83\u662f\u4e00\u79cd\u975e\u751f\u7269\u5236\u5242\uff0c\u8fd9\u610f\u5473\u7740\u5b83\u4e0d\u542b\u6d3b\u7ec6\u80de\u6216\u86cb\u767d\u8d28\u3002\u5bf9\u4e8e\u65e0\u6cd5\u8010\u53d7\u751f\u7269\u5236\u5242\u6216\u611f\u67d3\u98ce\u9669\u8f83\u9ad8\u7684\u60a3\u8005\u6765\u8bf4\uff0c\u8fd9\u662f\u4e00\u4e2a\u66f4\u5b89\u5168\u7684\u9009\u62e9\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u751f\u7269\u5236\u5242\u662f\u7531\u6d3b\u7ec6\u80de\u6216\u86cb\u767d\u8d28\u5236\u6210\u7684\u836f\u7269\uff0c\u5e38\u7528\u4e8e\u6cbb\u7597\u94f6\u5c51\u75c5\u548c\u94f6\u5c51\u75c5\u5173\u8282\u708e\u3002\u7136\u800c\uff0c\u751f\u7269\u5236\u5242\u53ef\u80fd\u4f1a\u589e\u52a0\u611f\u67d3\u98ce\u9669\uff0c\u5c24\u5176\u662f\u5728\u514d\u75ab\u7cfb\u7edf\u8f83\u5f31\u7684\u60a3\u8005\u4e2d\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u8bf7\u8bb0\u4f4f\uff0cOtezla \u5e76\u4e0d\u9002\u5408\u6240\u6709\u4eba\u3002<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u4e0d\u5efa\u8bae\u6709\u6291\u90c1\u75c7\u3001\u81ea\u6740\u60f3\u6cd5\u6216\u884c\u4e3a\u75c5\u53f2\u7684\u60a3\u8005\u4f7f\u7528\u5b83\uff0c\u56e0\u4e3a\u5b83\u53ef\u80fd\u4f1a\u52a0\u5267\u75c7\u72b6\u3002&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u5b83\u8fd8\u53ef\u80fd\u4e0e\u5176\u4ed6\u836f\u7269\uff08\u5982\u5229\u798f\u5e73\u3001\u5723\u7ea6\u7ff0\u8349\u548c\u5361\u9a6c\u897f\u5e73\uff09\u76f8\u4e92\u4f5c\u7528\uff0c\u56e0\u6b64\u4e0d\u5e94\u4e0e\u8fd9\u4e9b\u836f\u7269\u4e00\u8d77\u670d\u7528\u3002&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u56e0\u6b64\uff0c\u60a8\u5e94\u8be5\u59cb\u7ec8\u544a\u77e5\u533b\u751f\u60a8\u7684\u5065\u5eb7\u53f2\u4ee5\u53ca\u60a8\u53ef\u80fd\u6b63\u5728\u670d\u7528\u7684\u4efb\u4f55\u836f\u7269\u3002<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Otezla_Used_For\"><\/span>Otezla \u7684\u7528\u9014\u662f\u4ec0\u4e48\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u6279\u51c6\u7528\u4e8e\u6cbb\u7597\uff1a<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>\u6591\u5757\u72b6\u94f6\u5c51\u75c5<\/b><span style=\"font-weight: 400;\">\uff1aOtezla \u7528\u4e8e\u6cbb\u7597\u9002\u5408\u5168\u8eab\u6cbb\u7597\u6216\u5149\u7597\u7684\u6210\u4eba\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u3002&nbsp;<\/span><\/li>\n\n\n\n<li><b>\u94f6\u5c51\u75c5\u5173\u8282\u708e\uff1a<\/b><span style=\"font-weight: 400;\"> Otezla \u53ef\u5355\u72ec\u4f7f\u7528\u6216\u4e0e\u5176\u4ed6\u836f\u7269\u8054\u5408\u4f7f\u7528\uff0c\u6cbb\u7597\u6210\u4eba\u6d3b\u52a8\u6027\u94f6\u5c51\u75c5\u5173\u8282\u708e\u3002<\/span><\/li>\n\n\n\n<li><b>\u4e0e\u767d\u585e\u6c0f\u75c5\u76f8\u5173\u7684\u53e3\u8154\u6e83\u75a1\uff1a<\/b><span style=\"font-weight: 400;\"> Otezla \u7528\u4e8e\u6cbb\u7597\u4e0e\u53e3\u8154\u6e83\u75a1\u76f8\u5173\u7684 <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12980-behcets-disease\">\u767d\u585e\u6c0f\u75c5<\/a> \u5728\u6210\u5e74\u4eba\u4e2d\u3002<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Otezla_Used\"><\/span>Otezla\u5982\u4f55\u4f7f\u7528\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u4e3a\u53e3\u670d\u7247\u5242\u3002\u8bf7\u7528\u6c34\u541e\u670d\uff0c\u8bf7\u52ff\u538b\u788e\u3001\u5480\u56bc\u6216\u63b0\u5f00\u836f\u7247\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u8bf7\u52a1\u5fc5\u9075\u7167\u533b\u5631\u670d\u7528\u6b64\u836f\uff0c\u672a\u7ecf\u533b\u751f\u8bb8\u53ef\uff0c\u8bf7\u52ff\u66f4\u6539\u5242\u91cf\u6216\u505c\u836f\u3002Otezla \u53ef\u80fd\u9700\u8981\u6570\u5468\u624d\u80fd\u8d77\u6548\uff0c\u56e0\u6b64\u5e94\u6301\u7eed\u670d\u7528\u4ee5\u7ef4\u6301\u836f\u6548\u3002&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u9519\u8fc7\u4e00\u6b21\u5242\u91cf\uff0c\u60a8\u5e94\u8be5\u5728\u8bb0\u8d77\u65f6\u7acb\u5373\u670d\u7528\uff0c\u9664\u975e\u5df2\u7ecf\u63a5\u8fd1\u4e0b\u4e00\u6b21\u670d\u836f\u7684\u65f6\u95f4\uff0c\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\u60a8\u5e94\u8be5\u8df3\u8fc7\u9519\u8fc7\u7684\u5242\u91cf\u5e76\u7ee7\u7eed\u6309\u7167\u5e38\u89c4\u670d\u836f\u65f6\u95f4\u8868\u670d\u7528\u3002<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_It_Work\"><\/span>\u5b83\u662f\u5982\u4f55\u5de5\u4f5c\u7684\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5f53\u514d\u75ab\u7cfb\u7edf\u53cd\u5e94\u8fc7\u5ea6\uff0c\u4ea7\u751f\u8fc7\u591a\u7684\u708e\u75c7\u7ec6\u80de\u548c\u86cb\u767d\u8d28\u65f6\uff0c\u5c31\u4f1a\u5f15\u53d1\u708e\u75c7\u3002PDE4 \u662f\u4e00\u79cd\u9176\uff0c\u53ef\u4ee5\u5206\u89e3\u4e00\u79cd\u53eb\u505a <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cyclic_adenosine_monophosphate\">\u73af\u78f7\u9178\u817a\u82f7<\/a> \u73af\u78f7\u9178\u817a\u82f7\uff08cAMP\uff09\uff0c\u5b83\u63a7\u5236\u7740\u4f53\u5185\u7684\u708e\u75c7\u3002PDE4\u5728\u4f53\u5185\u5faa\u73af\u8d8a\u591a\uff0c\u5b83\u5206\u89e3\u7684\u73af\u78f7\u9178\u817a\u82f7\u5c31\u8d8a\u591a\uff0c\u5bfc\u81f4\u708e\u75c7\u52a0\u5267\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u901a\u8fc7\u6291\u5236 PDE4 \u6765\u63d0\u9ad8 cAMP \u6c34\u5e73\uff0c\u4ece\u800c\u51cf\u5c11\u708e\u75c7\u7ec6\u80de\u548c\u86cb\u767d\u8d28\u7684\u4ea7\u751f\u3002\u8fd9\u6709\u52a9\u4e8e\u63a7\u5236\u708e\u75c7\uff0c\u5e76\u51cf\u8f7b\u5173\u8282\u75bc\u75db\u3001\u80bf\u80c0\u548c\u76ae\u80a4\u708e\u75c7\u7b49\u75c7\u72b6\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cOtezla \u4e0d\u80fd\u6cbb\u6108\u708e\u75c7\uff0c\u4f46\u53ef\u4ee5\u5e2e\u52a9\u63a7\u5236\u708e\u75c7\u3002&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects\"><\/span>\u526f\u4f5c\u7528<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects.jpg\" alt=\"Woman suffering from Otezal side effects\" class=\"wp-image-22940\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">\u4e0e\u6240\u6709\u836f\u7269\u4e00\u6837\uff0cOtezla \u4e5f\u53ef\u80fd\u5f15\u8d77\u526f\u4f5c\u7528\u3002\u4ee5\u4e0b\u662f\u4e00\u4e9b\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528\uff1a<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u6076\u5fc3<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u8179\u6cfb<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u5934\u75db<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u4e0a\u547c\u5438\u9053\u611f\u67d3<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u7d27\u5f20\u6027\u5934\u75db<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u4f53\u91cd\u51cf\u8f7b<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u4e0d\u592a\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u5305\u62ec\uff1a<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u6cae\u4e27<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u81ea\u6740\u60f3\u6cd5\u6216\u884c\u4e3a<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u6291\u90c1\u6216\u7126\u8651\u52a0\u5267<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u8840\u7ba1\u6027\u6c34\u80bf\uff08\u5634\u5507\u3001\u820c\u5934\u6216\u9762\u90e8\u80bf\u80c0\uff09<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u4e25\u91cd\u8179\u6cfb<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u4e25\u91cd\u5455\u5410<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u5728\u670d\u7528 Otezla \u540e\u51fa\u73b0\u4efb\u4f55\u8fd9\u4e9b\u526f\u4f5c\u7528\u6216\u5176\u4ed6\u5f02\u5e38\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u8054\u7cfb\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u3002\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u4ee5\u5e2e\u52a9\u60a8\u786e\u5b9a\u6700\u4f73\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u5e94\u5bf9\u60a8\u53ef\u80fd\u9047\u5230\u7684\u4efb\u4f55\u526f\u4f5c\u7528\u3002<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Drug_Dosage\"><\/span>\u836f\u7269\u5242\u91cf<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u5e94\u9010\u6e10\u8c03\u6574\u81f3\u63a8\u8350\u5242\u91cf\uff0c\u6bcf\u65e5\u4e24\u6b21\uff0c\u6bcf\u6b21 30 \u6beb\u514b\u3002\u91c7\u7528\u5242\u91cf\u8c03\u6574\u65b9\u6848\u662f\u4e3a\u4e86\u964d\u4f4e\u51fa\u73b0\u80c3\u80a0\u9053 (GI) \u75c7\u72b6\u7684\u53ef\u80fd\u6027\u3002\u5177\u4f53\u65b9\u6848\u5982\u4e0b\uff1a&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 1 \u5929\uff1a\u65e9\u4e0a\u670d\u7528 10 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 2 \u5929\uff1a\u65e9\u4e0a 10 \u6beb\u514b\uff0c\u665a\u4e0a 10 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 3 \u5929\uff1a\u65e9\u4e0a 10 \u6beb\u514b\uff0c\u665a\u4e0a 20 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 4 \u5929\uff1a\u65e9\u4e0a 20 \u6beb\u514b\uff0c\u665a\u4e0a 20 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 5 \u5929\uff1a\u65e9\u4e0a 20 \u6beb\u514b\uff0c\u665a\u4e0a 30 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u7b2c 6 \u5929\u53ca\u4ee5\u540e\uff1a\u65e9\u4e0a 30 \u6beb\u514b\uff0c\u665a\u4e0a 30 \u6beb\u514b<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u7684\u80be\u810f\u53d7\u5230\u4e25\u91cd\u635f\u5bb3\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u4f1a\u6539\u53d8\u60a8\u7684\u836f\u7269\u5242\u91cf\u3002&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions\"><\/span>\u9632\u8303\u63aa\u65bd<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5728\u4f7f\u7528 Otezla \u4e4b\u524d\u548c\u4e4b\u540e\uff0c\u60a8\u5e94\u8be5\u91c7\u53d6\u4e00\u4e9b\u9884\u9632\u63aa\u65bd\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u4f7f\u7528\u836f\u7269\u524d\uff1a<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u6709\u4efb\u4f55\u8fc7\u654f\u6216\u75be\u75c5\uff0c\u6216\u8005\u6b63\u5728\u670d\u7528\u5176\u4ed6\u836f\u7269\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u751f\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u6000\u5b55\u6216\u8ba1\u5212\u6000\u5b55\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u751f\uff0c\u56e0\u4e3a Otezla \u5728\u6000\u5b55\u671f\u95f4\u53ef\u80fd\u4e0d\u5b89\u5168\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u5982\u679c\u60a8\u6709\u6291\u90c1\u75c7\u6216\u81ea\u6740\u5ff5\u5934\u75c5\u53f2\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u751f\uff0c\u56e0\u4e3a Otezla \u53ef\u80fd\u4f1a\u589e\u52a0\u6291\u90c1\u75c7\u6216\u81ea\u6740\u884c\u4e3a\u7684\u98ce\u9669\u3002<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u4f7f\u7528\u836f\u7269\u540e\uff1a<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u9075\u5faa\u533b\u751f\u5173\u4e8e\u5242\u91cf\u548c\u4f7f\u7528\u9891\u7387\u7684\u6307\u793a\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u8ddf\u8e2a\u60a8\u53ef\u80fd\u9047\u5230\u7684\u4efb\u4f55\u526f\u4f5c\u7528\u5e76\u62a5\u544a\u7ed9\u60a8\u7684\u533b\u751f\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u670d\u7528 Otezla \u65f6\u907f\u514d\u996e\u9152\uff0c\u56e0\u4e3a\u8fd9\u53ef\u80fd\u4f1a\u589e\u52a0\u809d\u635f\u4f24\u7684\u98ce\u9669\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u53ea\u6709\u5728\u54a8\u8be2\u533b\u751f\u540e\u624d\u80fd\u505c\u6b62\u670d\u7528 Otezla\uff0c\u56e0\u4e3a\u7a81\u7136\u505c\u836f\u53ef\u80fd\u4f1a\u5bfc\u81f4\u53cd\u5f39\u75c7\u72b6\u3002<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u5c06 Otezla \u5b58\u653e\u5728\u5ba4\u6e29\u4e0b\uff0c\u907f\u514d\u9633\u5149\u76f4\u5c04\u3002<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>\u6210\u672c<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u7684\u6210\u672c\u53ef\u80fd\u56e0\u591a\u79cd\u56e0\u7d20\u800c\u5f02\uff0c\u4f8b\u5982\u60a8\u7684\u56fd\u5bb6\u3001\u4fdd\u9669\u8303\u56f4\u548c\u5242\u91cf\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u5728\u7f8e\u56fd\uff0cOtezla \u7684\u5e73\u5747\u6279\u53d1\u4ef7 (AWP) \u7ea6\u4e3a\u6bcf\u7247 $153 \u7f8e\u5143\uff0c\u5efa\u8bae\u5242\u91cf\u4e3a\u6bcf\u5929\u4e24\u7247\u3002\u8fd9\u610f\u5473\u7740 60 \u7247\u836f\u7684\u4ef7\u683c\u7ea6\u4e3a $4,600 \u7f8e\u5143\uff0c\u76f8\u5f53\u4e8e\u4e00\u4e2a\u6708\u7684\u6cbb\u7597\u8d39\u7528\u3002<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u9700\u8981\u6ce8\u610f\u7684\u662f\uff0c\u6b64\u4ef7\u683c\u4ec5\u4e3a\u9884\u4f30\u4ef7\u683c\uff0c\u53ef\u80fd\u65e0\u6cd5\u53cd\u6620\u60a3\u8005\u8d2d\u4e70Otezla\u7684\u5b9e\u9645\u8d39\u7528\u3002\u60a3\u8005\u5e94\u54a8\u8be2\u5176\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u6216\u836f\u5242\u5e08\uff0c\u4ee5\u83b7\u53d6\u66f4\u51c6\u786e\u3001\u6700\u65b0\u7684\u4ef7\u683c\u4fe1\u606f\u3002&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u6b64\u5916\uff0c\u60a3\u8005\u8fd8\u53ef\u4ee5\u4eab\u53d7\u6298\u6263\u6216\u53c2\u52a0 <a href=\"https:\/\/ameripharmaspecialty.com\/zh\/financial-assistance\/\">\u8d22\u653f\u63f4\u52a9\u8ba1\u5212<\/a> \u4ee5\u5e2e\u52a9\u62b5\u6d88\u6210\u672c\u3002<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>\u5bf9\u4e8e\u6591\u5757\u6027\u94f6\u5c51\u75c5\u60a3\u8005\uff0c\u4e73\u818f\u6216\u8f6f\u818f\u7b49\u5c40\u90e8\u6cbb\u7597\u6709\u65f6\u6548\u679c\u4e0d\u4f73\u3002\u6591\u5757\u6027\u94f6\u5c51\u75c5\u662f\u4e00\u79cd\u7ec8\u8eab\u75be\u75c5\uff0c\u53cd\u590d\u53d1\u4f5c\u548c\u7f13\u89e3\u3002\u8bb8\u591a\u6591\u5757\u6027\u94f6\u5c51\u75c5\u60a3\u8005\u8fd8\u53ef\u80fd\u53d1\u5c55\u4e3a\u94f6\u5c51\u75c5\u5173\u8282\u708e\uff0c\u5bfc\u81f4\u5173\u8282\u5468\u56f4\u75bc\u75db\u3001\u80bf\u80c0\u548c\u708e\u75c7\u3002\u00a0<\/p>","protected":false},"author":27,"featured_media":22939,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[33],"class_list":["post-22936","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-dr-samantha-kaeberlein"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Otezla: An Effective Non-Biologic Option for Treating Plaque Psoriasis and Psoriatic Arthritis<\/title>\n<meta name=\"description\" content=\"Learn about Otezla and how it treats plaque psoriasis and psoriatic arthritis. 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