{"id":18571,"date":"2022-02-11T10:02:57","date_gmt":"2022-02-11T18:02:57","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/staging\/?p=18567"},"modified":"2026-03-19T14:56:29","modified_gmt":"2026-03-19T21:56:29","slug":"temozolomide-temodar","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/","title":{"rendered":"Temozolomide\uff08\u66ff\u83ab\u5511\u80fa\uff09\uff1a\u7528\u9014\u3001\u5b89\u5168\u6ce8\u610f\u4e8b\u9879\u3001\u526f\u4f5c\u7528\u53ca\u9884\u671f\u7597\u6548"},"content":{"rendered":"\n<p><span style=\"font-weight: 400;\">Temozolomide (pronounced [te moe ZOE loe mide]) is also known by the brand name Temodar. Temozolomide is an antineoplastic (anti-cancer) drug that belongs to a class called alkylating agents. It is a type of chemotherapy that prevents cancer cells from multiplying and slows down their growth.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#What_Is_Chemotherapy\" >What Is Chemotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Protection_From_Chemotherapy\" >Protection From Chemotherapy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#What_Is_Temozolomide_Used_For\" >What Is Temozolomide Used For?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Available_Formulations\" >Available Formulations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Directions_for_Use\" >Directions for Use<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Missed_Dose\" >Missed Dose<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Storage\" >Storage<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#What_To_Avoid_While_Taking_Temozolomide\" >What To Avoid While Taking Temozolomide?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Pregnancy_and_Temozolomide\" >Pregnancy and Temozolomide<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Temozolomide_Side_Effects\" >Temozolomide Side Effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Vomiting\" >Vomiting<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Hair_Loss\" >Hair Loss<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Liver_Complications\" >Liver Complications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Pneumocystis_Pneumonia_PCP\" >Pneumocystis Pneumonia (PCP)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Secondary_Malignancies\" >Secondary Malignancies<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Bone_Marrow_Suppression\" >Bone Marrow Suppression<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Allergic_Reactions\" >Allergic Reactions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#Precautions\" >Precautions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/ameripharmaspecialty.com\/zh\/discontinued\/temozolomide-temodar\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Chemotherapy\"><\/span>What Is Chemotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/ameripharmaspecialty.com\/oral-chemotherapy-cancer-drugs\/\">Chemotherapy<\/a> is a cancer treatment that uses medicines to damage or kill rapidly dividing cells, including both cancer and healthy cells.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Protection_From_Chemotherapy\"><\/span>Protection From Chemotherapy<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is considered a hazardous drug. Do not open, crush, or chew capsules. If a capsule is damaged or leaking, do not inhale the powder and avoid contact with the skin, eyes, or mouth. Follow your pharmacy\u2019s handling instructions and consider wearing gloves. It is essential to take appropriate precautions for receiving, handling, storing, administering, and disposing of this medication. If possible, pour the capsule directly from the bottle cap into your mouth to minimize touching it.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">For the injectable solution, a<\/span><span style=\"font-weight: 400;\">void inhalation or contact with skin if damaged or accidentally opened.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Temozolomide_Used_For\"><\/span><strong>What Is Temozolomide Used For?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide has been approved by the Food and Drug Administration (FDA) to treat <\/span><a href=\"https:\/\/www.aans.org\/en\/Patients\/Neurosurgical-Conditions-and-Treatments\/Glioblastoma-Multiforme\"><span style=\"font-weight: 400;\">glioblastoma<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/rarediseases.org\/rare-diseases\/anaplastic-astrocytoma\/\"><span style=\"font-weight: 400;\">anaplastic astrocytoma<\/span><\/a><span style=\"font-weight: 400;\"> (brain cancer), and many other cancers for off-label use.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Available_Formulations\"><\/span><b>Available Formulations<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is available in the form of oral capsules and as a solution for intravenous infusion. The capsules are available in six different strengths: 5 mg, 20 mg, 100 mg, 140 mg, 180 mg, and 250 mg. The intravenous solution is available in 100 mg strength and contains a polysorbate 80 ingredient.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Directions_for_Use\"><\/span><b>Directions for Use<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Take temozolomide with a full glass of water, preferably on an empty stomach or at bedtime. Taking it on an empty stomach or at bedtime may help ease nausea. It should be taken at the same time each day. If you are receiving radiation therapy, follow your oncology team\u2019s instructions on when to take temozolomide. The dose should not be more or less than what is prescribed.&nbsp;<\/p>\n\n\n\n<p>While taking the capsule, swallow it whole; do not open, break, crush, chew, or allow it to be dissolved in your mouth. Swallow the capsules whole with water. If vomiting occurs, do not readminister the dose again and wait until the next scheduled dose. If the capsules are opened or damaged, avoid inhalation or contact with the skin or mucous membranes.<\/p>\n\n\n\n<p>If you receive temozolomide by IV, it is given by a healthcare professional as an intravenous infusion over 90 minutes.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Missed_Dose\"><\/span><b>Missed Dose<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is taken on a set schedule. If you miss a dose, contact your oncology team or pharmacist for instructions. If you vomit after taking a dose, do not take an extra dose \u2014 take your next dose at the regular scheduled time.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Storage\"><\/span><b>Storage<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Store capsules in a cool, dry place at room temperature and ensure the bottle is tightly closed. If you receive temozolomide by IV infusion, it will be prepared and stored by the clinic\/pharmacy in accordance with the product instructions.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_To_Avoid_While_Taking_Temozolomide\"><\/span>What To Avoid While Taking Temozolomide?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">While taking temozolomide therapy, you must follow some precautions. Always tell your physician about any medications you are already taking. <\/span><b>Do not take any drug or medicine (even herbals, vitamins, or over-the-counter medications) without prior consent from your physician or pharmacist<\/b><span style=\"font-weight: 400;\">. They may have some significant interactions with temozolomide.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pregnancy_and_Temozolomide\"><\/span>Pregnancy and Temozolomide<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Pregnancy status must be checked prior to starting temozolomide therapy in women of childbearing age, and effective contraception must be used during treatment and for 6 months after the last dose. Males with female partners of reproductive potential should use effective contraception during treatment and for 3 months after the last dose. Temozolomide may cause fetal harm and is therefore not recommended for women who are breastfeeding during therapy. Breastfeeding should also be avoided for at least 1 week after the last dose.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Temozolomide_Side_Effects\"><\/span>Temozolomide Side Effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">As with any other medication, you may encounter side effects while taking temozolomide. A few things to remember are:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">You may not have all the side effects listed below. Many people may experience little to no side effects.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">The severity of side effects may vary from person to person, so don\u2019t compare your side effects with other people\u2019s experiences.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Most of the side effects will improve when therapy is discontinued.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">These side effects are easily manageable most of the time, either by readjusting the dose of <\/span><span style=\"font-weight: 400;\">temozolomide <\/span><span style=\"font-weight: 400;\">or using additional medications to treat the symptoms. Consult with your physician or pharmacist to explore available options.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Do not hide any symptoms; if you feel any discomfort, do not hesitate to tell your physician or pharmacist about it.<\/span><\/li>\n<\/ul>\n\n\n\n<p><b>Note<\/b><span style=\"font-weight: 400;\">: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Some of the more serious side effects of temozolomide are listed below:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Vomiting\"><\/span><span style=\"font-weight: 400;\">Vomiting<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is associated with a high potential for vomiting. For the prevention of nausea and vomiting, the use of <a href=\"http:\/\/www.aetna.com\/cpb\/medical\/data\/700_799\/0724.html\">antiemetic therapy<\/a> is highly recommended. Consult with your physician to see available options.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Hair_Loss\"><\/span><span style=\"font-weight: 400;\">Hair Loss<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">One of the most conspicuous side effects of chemotherapy encountered is hair loss. This happens because most chemotherapies, including <\/span><span style=\"font-weight: 400;\">temozolomide<\/span><span style=\"font-weight: 400;\">, act on rapidly dividing cancerous cells as well as healthy cells of the body like hair cells. However, the hair usually grows back once the chemotherapy is stopped.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Liver_Complications\"><\/span><span style=\"font-weight: 400;\">Liver Complications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">In certain cases, temozolomide can affect the liver and cause liver damage. The condition of the liver is monitored through blood tests that are able to detect liver function. Contact your physician immediately if you experience liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin or eyes. These may be indications of liver complications.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Pneumocystis_Pneumonia_PCP\"><\/span><span style=\"font-weight: 400;\">Pneumocystis Pneumonia (PCP)<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">PCP is a serious infection caused by a fungus that is very typical in patients who have a weakened immune system. Temozolomide lowers white blood cells, which weakens the immune system and increases the risk of PCP. The risk of PCP is increased in those receiving <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/corticosteroids\">corticosteroids<\/a> alongside temozolomide. In some treatment plans (for example, certain regimens used with radiation or newly diagnosed glioblastoma), your provider may prescribe PCP prophylaxis to reduce the risk of this infection. During therapy, if you experience difficulty breathing, fever, chills, or dry cough, contact your physician immediately.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Secondary_Malignancies\"><\/span><span style=\"font-weight: 400;\">Secondary Malignancies<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">It is possible that <\/span><span style=\"font-weight: 400;\">temozolomide <\/span><span style=\"font-weight: 400;\">can give rise to a secondary type of cancer during treatments, including myeloid leukemia. Continuous monitoring during treatment for new malignancies may be necessary.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Bone_Marrow_Suppression\"><\/span><span style=\"font-weight: 400;\">Bone Marrow Suppression<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">It is essential to keep up with regular blood tests, especially the <a href=\"https:\/\/my.clevelandclinic.org\/health\/diagnostics\/4053-complete-blood-count\">complete blood count test<\/a> (CBC). The CBC blood test is capable of detecting potential side effects of temozolomide, including <a href=\"https:\/\/www.britannica.com\/science\/leukopenia\">leukopenia<\/a> (low white blood cell levels), thrombocytopenia (low platelet count), and anemia (low red blood cells), all of which are potential side effects from the use of temozolomide. Patients over 65 years of age should take extra precautions with temozolomide use, as they may have a higher risk for bone marrow suppression.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Allergic_Reactions\"><\/span><span style=\"font-weight: 400;\">Allergic Reactions<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Allergic reactions are another rare side effect of <\/span><span style=\"font-weight: 400;\">temozolomide<\/span><span style=\"font-weight: 400;\">. A mild allergic reaction can include a rash on the skin, skin becoming itchy, etc. Severe side effects may include swelling under the eyes, lips, or hands and swelling of the throat or tongue with disturbed breathing. Immediately contact your physician if any signs of an allergic reaction are present.&nbsp;<\/span><\/p>\n\n\n\n<p><b>Other common side effects<\/b> <b>may include:<\/b><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Diarrhea or constipation<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dizziness or fatigue<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Change in appetite<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Muscle or joint pain<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Change in taste<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Dry skin<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nausea or vomiting<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions\"><\/span>Precautions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Unless approved by your physician, temozolomide is generally not recommended in <\/span><span style=\"font-weight: 400;\">patients who have an allergy to temozolomide. Allergic reactions can cause a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate, trouble breathing, and sweating. If you have any of these symptoms, stop using <\/span><span style=\"font-weight: 400;\">temozolomide <\/span><span style=\"font-weight: 400;\">and call your doctor or get emergency help right away.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><b>Is temozolomide a chemo agent?<\/b><\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is a chemotherapy drug (an alkylating agent). It works by damaging DNA in rapidly dividing cells, which can slow or stop cancer cell growth.<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><b>How should temozolomide be taken?<\/b><\/h4>\n\n\n\n<p>Take temozolomide at the same time each day with a full glass of water, preferably on an empty stomach or at bedtime. When taking the capsule, swallow it whole; do not open, break, crush, chew, or allow it to be dissolved in your mouth.<\/p>\n\n\n\n<p>If you receive temozolomide by IV, it is given by a healthcare professional as an intravenous infusion over 90 minutes.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><b>Can you lose your hair with temozolomide?<\/b><\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Like other chemotherapeutic agents, temozolomide has the potential to cause hair loss.&nbsp;<\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><b>Can you touch temozolomide?<\/b><\/h4>\n\n\n\n<p><span style=\"font-weight: 400;\">Temozolomide is considered a hazardous drug, so avoid direct contact and do not open, crush, or chew the capsules. If you must handle a capsule, consider wearing gloves or pouring it directly into your mouth from the bottle cap to minimize contact. If a capsule is damaged or leaking, avoid contact with the powder and follow your pharmacy\u2019s instructions.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Temozolomide (pronounced [te moe ZOE loe mide]) is also known by the brand name Temodar. Temozolomide is an antineoplastic (anti-cancer) drug that belongs to a class called alkylating agents. It is a type of chemotherapy that prevents cancer cells from multiplying and slows down their growth.<\/p>\n","protected":false},"author":11,"featured_media":18573,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[11],"class_list":["post-18571","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-dr-dania-jaradat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Temozolomide (Temodar): Uses, Safety Precautions, Side Effects, and What to Expect - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Temozolomide is an antineoplastic (anti-cancer) drug that belongs to a class called alkylating agents. 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It is a type of chemotherapy that prevents cancer cells from multiplying and slows down their growth.","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-150x150.jpeg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-300x200.jpeg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-1024x682.jpeg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",600,400,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-330x220.jpeg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-1146x380.jpeg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-86x57.jpeg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-167x111.jpeg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-280x187.jpeg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-370x247.jpeg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient-960x640.jpeg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/02\/temozolomide-patient.jpeg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Dania Jaradat, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/zh\/author\/dania-jaradat\/"},"rttpg_comment":1,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/zh\/category\/discontinued\/\" rel=\"category tag\">Discontinued<\/a>","rttpg_excerpt":"Temozolomide (pronounced [te moe ZOE loe mide]) is also known by the brand name Temodar. Temozolomide is an antineoplastic (anti-cancer) drug that belongs to a class called alkylating agents. It is a type of chemotherapy that prevents cancer cells from multiplying and slows down their growth.","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/posts\/18571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/comments?post=18571"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/posts\/18571\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/media\/18573"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/media?parent=18571"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/categories?post=18571"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/zh\/wp-json\/wp\/v2\/tags?post=18571"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}