{"id":27841,"date":"2025-10-14T16:59:22","date_gmt":"2025-10-14T23:59:22","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=27841"},"modified":"2025-10-14T17:00:24","modified_gmt":"2025-10-15T00:00:24","slug":"ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/","title":{"rendered":"IVIG cho b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng lo\u1ea1i \u1edf tr\u1ebb s\u01a1 sinh (HDN)"},"content":{"rendered":"<p>C\u00e1c nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe \u0111\u00f4i khi khuy\u1ebfn ngh\u1ecb <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig\/\">IVIG<\/a> \u0111i\u1ec1u tr\u1ecb khi ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ban \u0111\u1ea7u, nh\u01b0 li\u1ec7u ph\u00e1p quang tr\u1ecb, kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi tr\u1ebb s\u01a1 sinh m\u1eafc b\u1ec7nh tan m\u00e1u mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i (HDN).&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-cae9c8a05a97ae180a30ab7c2c1f163c\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 cho ph\u00e9p tr\u01b0\u1edbc c\u1ee7a IVIG\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng c\u00f3 kh\u1ea3 n\u0103ng \u0111e d\u1ecda t\u00ednh m\u1ea1ng, ph\u00e1t tri\u1ec3n khi c\u00f3 s\u1ef1 b\u1ea5t t\u01b0\u01a1ng th\u00edch nh\u00f3m m\u00e1u gi\u1eefa m\u1eb9 v\u00e0 con. S\u1ef1 b\u1ea5t t\u01b0\u01a1ng th\u00edch n\u00e0y g\u00e2y ra s\u1ef1 ph\u00e1 h\u1ee7y nhanh ch\u00f3ng c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a tr\u1ebb (tan m\u00e1u), d\u1eabn \u0111\u1ebfn v\u00e0ng da ngay sau khi sinh.&nbsp;<\/p>\n\n\n\n<p>Quang tr\u1ecb li\u1ec7u l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u tay. Khi kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t HDN \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf nh\u1eefng tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng, truy\u1ec1n m\u00e1u thay th\u1ebf (BET) \u0111\u01b0\u1ee3c xem l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u1ee9 hai. Tuy nhi\u00ean, \u0111i\u1ec1u tr\u1ecb BET mang l\u1ea1i nh\u1eefng r\u1ee7i ro \u0111\u00e1ng k\u1ec3 cho tr\u1ebb s\u01a1 sinh, v\u00e0 \u0111\u1ec3 tr\u00e1nh \u0111i\u1ec1u n\u00e0y, li\u1ec7u ph\u00e1p IVIG th\u01b0\u1eddng \u0111\u01b0\u1ee3c coi l\u00e0 m\u1ed9t li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3.&nbsp;<\/p>\n\n\n\n<p>Tr\u00ean th\u1ef1c t\u1ebf, nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng <a href=\"https:\/\/www.dovepress.com\/immunoglobulin-transfusion-in-hemolytic-disease-of-the-newborn-place-i-peer-reviewed-fulltext-article-IJCTM#ref15\">Li\u1ec7u ph\u00e1p IVIG an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3<\/a> d\u00e0nh cho b\u1ec7nh nh\u00e2n HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i, v\u00ec n\u00f3 l\u00e0m gi\u1ea3m nhu c\u1ea7u th\u1ef1c hi\u1ec7n c\u00e1c th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n v\u00e0 r\u1ee7i ro h\u01a1n nh\u01b0 BET. \u0110\u1ecdc ti\u1ebfp \u0111\u1ec3 t\u00ecm hi\u1ec3u v\u1ec1 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng lo\u1ea1i <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/hemolytic-disease-of-the-newborn-causes-symptoms-treatment-and-prevention\/\">b\u1ec7nh tan m\u00e1u \u1edf tr\u1ebb s\u01a1 sinh<\/a> (HDN) l\u00e0 g\u00ec v\u00e0 IVIG c\u00f3 th\u1ec3 gi\u00fap \u00edch cho tr\u1ebb s\u01a1 sinh nh\u01b0 th\u1ebf n\u00e0o.&nbsp;&nbsp;<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#Isoimmune_Hemolytic_Disease_of_the_Newborn_HDN_Overview\" >B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN): T\u1ed5ng quan<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#Common_Symptoms_of_Isoimmune_HDN\" >C\u00e1c tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p c\u1ee7a HDN Isoimmune<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#IVIG_and_Isoimmune_Hemolytic_Disease_of_the_Newborn_HDN\" >IVIG v\u00e0 B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN)<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#How_IVIG_Works_in_Isoimmune_Hemolytic_Disease_of_the_Newborn\" >IVIG ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o trong b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng lo\u1ea1i \u1edf tr\u1ebb s\u01a1 sinh\u00a0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#Recommended_Dosage_of_IVIG_for_Isoimmune_Hemolytic_Disease_of_the_Newborn\" >Li\u1ec1u l\u01b0\u1ee3ng khuy\u1ebfn c\u00e1o c\u1ee7a IVIG cho b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng lo\u1ea1i \u1edf tr\u1ebb s\u01a1 sinh\u00a0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#Reported_Adverse_Effects_of_IVIG\" >T\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o c\u1ee7a IVIG<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/#Key_Takeaway\" >\u0110i\u1ec3m ch\u00ednh<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Isoimmune_Hemolytic_Disease_of_the_Newborn_HDN_Overview\"><\/span>B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN): T\u1ed5ng quan<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN) l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd do mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh. T\u00ecnh tr\u1ea1ng n\u00e0y th\u01b0\u1eddng x\u1ea3y ra khi m\u1eb9 v\u00e0 con c\u00f3 nh\u00f3m m\u00e1u kh\u00e1c nhau (A, B, AB ho\u1eb7c O) v\u00e0 y\u1ebfu t\u1ed1 Rh (d\u01b0\u01a1ng t\u00ednh ho\u1eb7c \u00e2m t\u00ednh).&nbsp;&nbsp;<\/p>\n\n\n\n<p>Trong h\u1ea7u h\u1ebft c\u00e1c tr\u01b0\u1eddng h\u1ee3p, HDN \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t b\u1edfi s\u1ef1 kh\u00f4ng t\u01b0\u01a1ng th\u00edch y\u1ebfu t\u1ed1 Rh. Y\u1ebfu t\u1ed1 Rh l\u00e0 m\u1ed9t protein (kh\u00e1ng nguy\u00ean D) c\u00f3 tr\u00ean h\u1ed3ng c\u1ea7u (RBC).&nbsp;<\/p>\n\n\n\n<p>Khi ng\u01b0\u1eddi m\u1eb9 c\u00f3 nh\u00f3m m\u00e1u Rh \u00e2m t\u00ednh (kh\u00f4ng c\u00f3 protein Rh) sinh con c\u00f3 nh\u00f3m m\u00e1u Rh d\u01b0\u01a1ng t\u00ednh (di truy\u1ec1n t\u1eeb ng\u01b0\u1eddi cha), h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a ng\u01b0\u1eddi m\u1eb9 s\u1ebd coi c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a em b\u00e9 l\u00e0 \u201cv\u1eadt l\u1ea1\u201d v\u00e0 s\u1ea3n xu\u1ea5t kh\u00e1ng th\u1ec3 ch\u1ed1ng l\u1ea1i ch\u00fang.&nbsp;<\/p>\n\n\n\n<p>Nh\u1eefng kh\u00e1ng th\u1ec3 n\u00e0y \u0111i qua nhau thai trong thai k\u1ef3 v\u00e0 t\u1ea5n c\u00f4ng c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u Rh d\u01b0\u01a1ng c\u1ee7a em b\u00e9. Khi c\u00e1c kh\u00e1ng th\u1ec3 ph\u00e1 h\u1ee7y c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u, em b\u00e9 s\u1ebd b\u1ecb b\u1ec7nh. T\u00ecnh tr\u1ea1ng n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh h\u1ed3ng c\u1ea7u b\u00e0o thai trong thai k\u1ef3. Sau khi em b\u00e9 ch\u00e0o \u0111\u1eddi, t\u00ecnh tr\u1ea1ng n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN).<\/p>\n\n\n\n<p>Ngay sau khi sinh, tr\u1ebb s\u01a1 sinh c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng thi\u1ebfu m\u00e1u v\u00e0 v\u00e0ng da, nh\u01b0 v\u00e0ng da\/m\u1eaft do n\u1ed3ng \u0111\u1ed9 bilirubin cao (m\u1ed9t ch\u1ea5t m\u00e0u v\u00e0ng \u0111\u01b0\u1ee3c gi\u1ea3i ph\u00f3ng trong qu\u00e1 tr\u00ecnh ph\u00e1 h\u1ee7y h\u1ed3ng c\u1ea7u).&nbsp;<\/p>\n\n\n\n<p>V\u00ec gan c\u1ee7a tr\u1ebb s\u01a1 sinh v\u1eabn ch\u01b0a tr\u01b0\u1edfng th\u00e0nh v\u00e0 kh\u00f4ng th\u1ec3 x\u1eed l\u00fd v\u00e0 lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng bilirubin d\u01b0 th\u1eeba m\u1ed9t c\u00e1ch nhanh ch\u00f3ng n\u00ean n\u00f3 b\u1eaft \u0111\u1ea7u t\u00edch t\u1ee5 trong m\u00e1u c\u1ee7a tr\u1ebb, g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng thi\u1ebfu m\u00e1u v\u00e0 v\u00e0ng da.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Common_Symptoms_of_Isoimmune_HDN\"><\/span>C\u00e1c tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p c\u1ee7a HDN Isoimmune<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN) c\u00f3 th\u1ec3 kh\u00e1c nhau \u1edf m\u1ed7i tr\u1ebb. M\u1ed9t s\u1ed1 tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn m\u00e0 tr\u1ebb s\u01a1 sinh c\u00f3 th\u1ec3 bi\u1ec3u hi\u1ec7n sau khi sinh bao g\u1ed3m:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Da nh\u1ee3t nh\u1ea1t v\u00e0 v\u00e0ng da (da, m\u1eaft v\u00e0 d\u00e2y r\u1ed1n chuy\u1ec3n sang m\u00e0u v\u00e0ng) do thi\u1ebfu m\u00e1u<\/li>\n\n\n\n<li>Gan v\u00e0 l\u00e1ch to<\/li>\n\n\n\n<li>S\u1ef1 u\u1ec3 o\u1ea3i<\/li>\n\n\n\n<li>Nh\u1ecbp tim nhanh<\/li>\n\n\n\n<li>Ph\u00f9 thai nhi (s\u01b0ng to\u00e0n b\u1ed9 c\u01a1 th\u1ec3 nghi\u00eam tr\u1ecdng)<\/li>\n\n\n\n<li><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/25014-kernicterus\">V\u00e0ng da nh\u00e2n<\/a> (t\u1ed5n th\u01b0\u01a1ng n\u00e3o do t\u00edch t\u1ee5 nhi\u1ec1u bilirubin trong m\u00e1u)<\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-c3f8803c373a456c5708943597e391c1\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tTham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a chuy\u00ean gia IVIG\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">T\u00ecm hi\u1ec3u th\u00eam<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_and_Isoimmune_Hemolytic_Disease_of_the_Newborn_HDN\"><\/span>IVIG v\u00e0 B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh (HDN)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"246\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom.jpg\" alt=\"A mother holding her newborn baby\" class=\"wp-image-27844\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-300x176.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-18x12.jpg 18w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-86x50.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-167x98.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-280x164.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2025\/10\/baby-mom-370x217.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>H\u01b0\u1edbng d\u1eabn th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng n\u0103m 2022 c\u1ee7a Vi\u1ec7n H\u00e0n l\u00e2m Nhi khoa Hoa K\u1ef3 (AAP) khuy\u1ebfn c\u00e1o ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng IVIG trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i n\u1eb7ng, ch\u1ecdn l\u1ecdc, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>T\u1ed5ng l\u01b0\u1ee3ng bilirubin trong huy\u1ebft thanh (TSB) v\u1eabn ti\u1ebfp t\u1ee5c t\u0103ng m\u1eb7c d\u00f9 \u0111\u00e3 s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u chuy\u00ean s\u00e2u.\u00a0<\/li>\n\n\n\n<li>M\u1ee9c bilirubin (2 \u2013 3 mg\/dl) g\u1ea7n \u0111\u1ebfn m\u1ee9c c\u1ea7n ph\u1ea3i truy\u1ec1n m\u00e1u.<\/li>\n\n\n\n<li>Truy\u1ec1n m\u00e1u c\u00f3 th\u1ec3 g\u00e2y nguy hi\u1ec3m cho em b\u00e9 ho\u1eb7c kh\u00f4ng th\u1ef1c hi\u1ec7n \u0111\u01b0\u1ee3c.<\/li>\n<\/ul>\n\n\n\n<p>C\u00e1c b\u00e0i b\u00e1o quan s\u00e1t v\u00e0 \u0111\u00e1nh gi\u00e1 b\u00e1o c\u00e1o r\u1eb1ng vi\u1ec7c b\u1ed5 sung IVIG v\u00e0o li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u chuy\u00ean s\u00e2u trong HDN do kh\u00e1ng th\u1ec3 trung gian (Rh ho\u1eb7c ABO \u0111\u00e1ng k\u1ec3) c\u00f3 th\u1ec3 <a href=\"https:\/\/www.mdpi.com\/2227-9067\/10\/3\/496\">t\u0103ng bilirubin ch\u1eadm<\/a> V\u00e0<strong> <\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2531137924000725?via%3Dihub\">c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nhu c\u1ea7u truy\u1ec1n m\u00e1u thay th\u1ebf<\/a> \u1edf m\u1ed9t s\u1ed1 tr\u1ebb s\u01a1 sinh \u0111\u01b0\u1ee3c ch\u1ecdn.&nbsp;<\/p>\n\n\n\n<p>T\u01b0\u01a1ng t\u1ef1 nh\u01b0 v\u1eady, tr\u01b0\u1edbc \u0111\u00f3 <a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Pediatrics.&amp;title=A%20decline%20in%20the%20frequency%20of%20neonatal%20exchange%20transfusions%20and%20its%20effect%20on%20exchange-related%20morbidity%20and%20mortality&amp;author=LA%20Steiner&amp;author=MJ%20Bizzarro&amp;author=RA%20Ehrenkranz&amp;author=PG%20Gallagher&amp;volume=120&amp;publication_year=2007&amp;pages=27-32&amp;pmid=17606558&amp;doi=10.1542\/peds.2006-2910&amp;\">th\u1eed nghi\u1ec7m c\u00f3 \u0111\u1ed1i ch\u1ee9ng ng\u1eabu nhi\u00ean<\/a> cho th\u1ea5y IVIG c\u00f3 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb tr\u1ebb s\u01a1 sinh b\u1ecb v\u00e0ng da tan m\u00e1u v\u00e0 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 nhu c\u1ea7u truy\u1ec1n m\u00e1u thay th\u1ebf. T\u01b0\u01a1ng t\u1ef1 nh\u01b0 v\u1eady, trong m\u1ed9t <a href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/NPM-230070\">lo\u1ea1t tr\u01b0\u1eddng h\u1ee3p<\/a> trong s\u1ed1 11 tr\u1ebb s\u01a1 sinh m\u1eafc b\u1ec7nh tan m\u00e1u mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i (HDN), khi \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng 3 \u2013 4 li\u1ec1u IVIG, n\u1ed3ng \u0111\u1ed9 bilirubin \u0111\u1ec1u gi\u1ea3m xu\u1ed1ng d\u01b0\u1edbi ng\u01b0\u1ee1ng truy\u1ec1n m\u00e1u thay m\u00e1u trong m\u1ecdi tr\u01b0\u1eddng h\u1ee3p.<\/p>\n\n\n\n<p>H\u01a1n n\u1eefa, m\u1ed9t <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/09732179231151761\">Nghi\u00ean c\u1ee9u \u0111o\u00e0n h\u1ec7 h\u1ed3i c\u1ee9u n\u0103m 2023<\/a> c\u0169ng b\u00e1o c\u00e1o nh\u1eefng l\u1ee3i \u00edch ti\u1ec1m n\u0103ng c\u1ee7a IVIG trong vi\u1ec7c gi\u1ea3m nhu c\u1ea7u truy\u1ec1n m\u00e1u thay th\u1ebf trong HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i. Tuy nhi\u00ean, b\u1eb1ng ch\u1ee9ng ch\u1ea5t l\u01b0\u1ee3ng cao nh\u00ecn chung v\u1eabn c\u00f2n m\u01a1 h\u1ed3.&nbsp;<\/p>\n\n\n\n<p>Hi\u1ec7n t\u1ea1i <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18170\">h\u01b0\u1edbng d\u1eabn<\/a> khuy\u00ean ch\u1ec9 s\u1eed d\u1ee5ng IVIG trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i. V\u00ed d\u1ee5, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35415922\/\">h\u1ed9i \u0111\u1ed3ng qu\u1ed1c t\u1ebf<\/a> \u0111\u1ec1 xu\u1ea5t r\u1eb1ng IVIG kh\u00f4ng n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb HDN do Rh ho\u1eb7c ABO trung gian, nh\u01b0ng ch\u1ec9 n\u00ean c\u00e2n nh\u1eafc khi kh\u00f4ng th\u1ec3 th\u1ef1c hi\u1ec7n truy\u1ec1n m\u00e1u thay th\u1ebf m\u1ed9t c\u00e1ch d\u1ec5 d\u00e0ng.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_IVIG_Works_in_Isoimmune_Hemolytic_Disease_of_the_Newborn\"><\/span>IVIG ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o trong b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng lo\u1ea1i \u1edf tr\u1ebb s\u01a1 sinh\u00a0<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng ch\u00ednh x\u00e1c c\u1ee7a IVIG trong HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng lo\u1ea1i v\u1eabn ch\u01b0a r\u00f5 r\u00e0ng, nh\u01b0ng c\u00e1c nghi\u00ean c\u1ee9u ch\u1ee9ng minh r\u1eb1ng <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18170\">IVIG ng\u0103n ch\u1eb7n \u0111\u1ea1i th\u1ef1c b\u00e0o<\/a> (m\u1ed9t lo\u1ea1i t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch tham gia v\u00e0o qu\u00e1 tr\u00ecnh ph\u00e1 h\u1ee7y h\u1ed3ng c\u1ea7u c\u1ee7a tr\u1ebb s\u01a1 sinh).&nbsp;<\/p>\n\n\n\n<p>Tr\u1ebb s\u01a1 sinh m\u1eafc b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch c\u00f3 c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u \u0111\u01b0\u1ee3c ph\u1ee7 kh\u00e1ng th\u1ec3 c\u1ee7a m\u1eb9. C\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch c\u1ee7a tr\u1ebb (t\u1ee9c l\u00e0 \u0111\u1ea1i th\u1ef1c b\u00e0o) nh\u1eadn di\u1ec7n v\u00e0 ti\u00eau di\u1ec7t c\u00e1c h\u1ed3ng c\u1ea7u \u0111\u01b0\u1ee3c ph\u1ee7 kh\u00e1ng th\u1ec3 n\u00e0y, d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng h\u1ed3ng c\u1ea7u th\u1ea5p (thi\u1ebfu m\u00e1u) v\u00e0 n\u1ed3ng \u0111\u1ed9 bilirubin cao (v\u00e0ng da) \u1edf tr\u1ebb s\u01a1 sinh.&nbsp;<\/p>\n\n\n\n<p>IVIG ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh n\u00e0y. C\u00e1c kh\u00e1ng th\u1ec3 do \u0111i\u1ec1u tr\u1ecb IVIG cung c\u1ea5p s\u1ebd li\u00ean k\u1ebft v\u1edbi c\u00e1c th\u1ee5 th\u1ec3 tr\u00ean \u0111\u1ea1i th\u1ef1c b\u00e0o v\u00e0 ng\u0103n ch\u00fang t\u1ea5n c\u00f4ng c\u00e1c h\u1ed3ng c\u1ea7u \u0111\u01b0\u1ee3c ph\u1ee7 kh\u00e1ng th\u1ec3 c\u1ee7a em b\u00e9.&nbsp;<\/p>\n\n\n\n<p>B\u1eb1ng c\u00e1ch n\u00e0y, IVIG l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y h\u1ed3ng c\u1ea7u c\u1ee7a tr\u1ebb, gi\u1ea3m n\u1ed3ng \u0111\u1ed9 bilirubin v\u00e0 gi\u1ea3m nguy c\u01a1 bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Recommended_Dosage_of_IVIG_for_Isoimmune_Hemolytic_Disease_of_the_Newborn\"><\/span>Li\u1ec1u l\u01b0\u1ee3ng khuy\u1ebfn c\u00e1o c\u1ee7a IVIG cho b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng lo\u1ea1i \u1edf tr\u1ebb s\u01a1 sinh\u00a0<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Theo H\u01b0\u1edbng d\u1eabn Th\u1ef1c h\u00e0nh L\u00e2m s\u00e0ng AAP 2022 v\u00e0 Hi\u1ec7p h\u1ed9i Nhi khoa Canada, li\u1ec1u IVIG khuy\u1ebfn c\u00e1o cho HDN mi\u1ec5n d\u1ecbch \u0111\u1ed3ng th\u1eddi l\u00e0 0,5 \u2013 1 g\/kg trong h\u01a1n 2 gi\u1edd khi n\u1ed3ng \u0111\u1ed9 bilirubin to\u00e0n ph\u1ea7n trong huy\u1ebft thanh t\u0103ng m\u1eb7c d\u00f9 \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u chuy\u00ean s\u00e2u ho\u1eb7c n\u1ebfu n\u1ed3ng \u0111\u1ed9 cao h\u01a1n 2 \u2013 3 mg\/dl so v\u1edbi n\u1ed3ng \u0111\u1ed9 trao \u0111\u1ed5i.&nbsp;<\/p>\n\n\n\n<p>M\u1ed8T<strong> <\/strong>C\u00f3 th\u1ec3 ti\u00eam li\u1ec1u IVIG th\u1ee9 hai sau 12 gi\u1edd n\u1ebfu c\u1ea7n.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Reported_Adverse_Effects_of_IVIG\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o c\u1ee7a IVIG<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u0110i\u1ec1u tr\u1ecb b\u1eb1ng IVIG nh\u00ecn chung \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t. Tuy nhi\u00ean, \u1edf tr\u1ebb s\u01a1 sinh, r\u1ee7i ro r\u1ea5t cao v\u00e0 v\u1ea5n \u0111\u1ec1 an to\u00e0n r\u1ea5t quan tr\u1ecdng. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y \u0111\u00e3 b\u00e1o c\u00e1o r\u1eb1ng IVIG c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 vi\u00eam ru\u1ed9t ho\u1ea1i t\u1eed (NEC).<strong>&nbsp;<\/strong><\/p>\n\n\n\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ti\u1ec1m \u1ea9n kh\u00e1c \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o trong <a href=\"https:\/\/www.mdpi.com\/2227-9067\/10\/3\/496\">lo\u1ea1t ca b\u1ec7nh s\u01a1 sinh<\/a> l\u00e0 huy\u1ebft kh\u1ed1i, ph\u1ea3n v\u1ec7, d\u1ecbch chuy\u1ec3n v\u00e0 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-0f5cf51ab37c6541ada8710374a5b576\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn h\u1ed7 tr\u1ee3 \u0111\u1ed3ng thanh to\u00e1n IVIG\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Key_Takeaway\"><\/span>\u0110i\u1ec3m ch\u00ednh<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>H\u1ea7u h\u1ebft tr\u1ebb s\u01a1 sinh m\u1eafc b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n (HDN) \u0111\u1ec1u c\u1ea3i thi\u1ec7n ch\u1ec9 v\u1edbi li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u. IVIG ch\u1ec9 \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n nghi\u00eam tr\u1ecdng \u1edf tr\u1ebb s\u01a1 sinh khi li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3 v\u00e0 truy\u1ec1n m\u00e1u c\u00f3 nguy c\u01a1 cao h\u01a1n.<\/p>","protected":false},"excerpt":{"rendered":"<p>C\u00e1c nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe \u0111\u00f4i khi khuy\u1ebfn ngh\u1ecb \u0111i\u1ec1u tr\u1ecb b\u1eb1ng IVIG khi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ban \u0111\u1ea7u, ch\u1eb3ng h\u1ea1n nh\u01b0 li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u, kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi tr\u1ebb s\u01a1 sinh m\u1eafc b\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch (HDN). B\u1ec7nh tan m\u00e1u \u0111\u1ed3ng mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng c\u00f3 kh\u1ea3 n\u0103ng \u0111e d\u1ecda t\u00ednh m\u1ea1ng, ph\u00e1t tri\u1ec3n khi c\u00f3 s\u1ef1 b\u1ea5t t\u01b0\u01a1ng th\u00edch nh\u00f3m m\u00e1u gi\u1eefa m\u1eb9 v\u00e0 con.<\/p>","protected":false},"author":25,"featured_media":27842,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[31],"class_list":["post-27841","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig","tag-dr-mark-alfonso"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IVIG for Isoimmune Hemolytic Disease of the Newborn (HDN) - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn what isoimmune hemolytic disease of the newborn (HDN) is and how IVIG can help newborns with this condition.\u00a0\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-isoimmune-hemolytic-disease-of-newborn-hdn\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IVIG for Isoimmune Hemolytic Disease of the Newborn (HDN) - 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