{"id":26571,"date":"2024-09-19T14:52:03","date_gmt":"2024-09-19T21:52:03","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26571"},"modified":"2024-09-19T14:52:05","modified_gmt":"2024-09-19T21:52:05","slug":"ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/","title":{"rendered":"IVIG cho b\u1ec7nh vi\u00eam c\u00e2n m\u1ea1c ho\u1ea1i t\u1eed nhi\u1ec5m \u0111\u1ed9c: B\u1eb1ng ch\u1ee9ng cho th\u1ea5y \u0111i\u1ec1u g\u00ec?"},"content":{"rendered":"\n<p><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/\">IVIG<\/a> for toxic necrotizing fasciitis may be an option in certain cases. While a few studies show benefits, its use is controversial.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-41cb87746a79bec8281e41a195582bee\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tConsult an IVIG Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#Highlights\" >Highlights<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#A_Quick_Overview_of_Necrotizing_Fasciitis\" >A Quick Overview of Necrotizing Fasciitis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#Can_You_Use_IVIG_for_Toxic_Necrotizing_Fasciitis\" >Can You Use IVIG for Toxic Necrotizing Fasciitis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#IVIG_for_Toxic_Necrotizing_Fasciitis_Understanding_the_Mechanism\" >IVIG for Toxic Necrotizing Fasciitis: Understanding the Mechanism<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#IVIG_for_Toxic_Necrotizing_Fasciitis_The_Challenges_Ahead\" >IVIG for Toxic Necrotizing Fasciitis: The Challenges Ahead<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-toxic-necrotizing-fasciitis-what-the-evidence-says\/#IVIG_for_Toxic_Necrotizing_Fasciitis_Frequently_Asked_Questions\" >IVIG for Toxic Necrotizing Fasciitis: Frequently Asked Questions<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Highlights\"><\/span>Highlights<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Necrotizing fasciitis is a rare, aggressive bacterial infection. Delayed treatment may result in multiple organ failure and death.<\/li>\n\n\n\n<li>Surgery and antibiotics are the mainstay of therapy; IVIG is an experimental treatment.\u00a0<\/li>\n\n\n\n<li>IVIG may be an option if you\u2019re critically ill and have unstable blood pressure.<\/li>\n\n\n\n<li>It\u2019s best to administer IVIG on a case-by-case basis.\u00a0<\/li>\n\n\n\n<li>IVIG may be particularly effective in necrotizing fasciitis caused by Group A Streptococcus (GAS).\u00a0<\/li>\n\n\n\n<li>More evidence from larger trials is needed to establish the benefits of IVIG for toxic necrotizing fasciitis.\u00a0<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_Quick_Overview_of_Necrotizing_Fasciitis\"><\/span>A Quick Overview of Necrotizing Fasciitis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Necrotizing fasciitis causes death (necrosis) of the <a href=\"https:\/\/my.clevelandclinic.org\/health\/body\/23251-fascia\">fascia<\/a> and tissues beneath your skin. The fascia is a thin layer of connective tissue that surrounds your muscles, bones, and organs.<\/p>\n\n\n\n<p>Other names of this condition are:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Flesh-eating disease<\/li>\n\n\n\n<li>Streptococcal gangrene<\/li>\n\n\n\n<li>Suppurative fasciitis<\/li>\n<\/ul>\n\n\n\n<p>Necrotizing fasciitis affects about four in one million Americans each year [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430756\/\">1<\/a>]. It can occur when a bacterium or several bacteria enter the body and produce toxins. These toxins limit blood supply to tissues and damage cells, causing pus-filled lesions.&nbsp;<\/p>\n\n\n\n<p>If the toxins reach your bloodstream, it may result in toxic shock.&nbsp;<\/p>\n\n\n\n<p>Bacteria associated with a necrotizing infection include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/5911-group-a-streptococcal-infections\">Group A Streptococci<\/a> (Streptococcus pyogenes)<\/li>\n\n\n\n<li>Staphylococcus aureus<\/li>\n\n\n\n<li>Klebsiella pneumoniae<\/li>\n\n\n\n<li>Escherichia coli<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_You_Use_IVIG_for_Toxic_Necrotizing_Fasciitis\"><\/span>Can You Use IVIG for Toxic Necrotizing Fasciitis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient.jpg\" alt=\"Toxic necrotizing fasciitis Patient receiving IVIG treatment at home\" class=\"wp-image-26574\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-patient-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>Possibly. Few studies have looked into the potential benefits of IVIG for necrotizing fasciitis. Below are some of them.&nbsp;<\/p>\n\n\n\n<p>According to a 2015 case report, IVIG may be an option in critically ill patients with unstable blood pressure [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4539184\/\">2<\/a>]. In this case, a person who didn\u2019t respond to antibiotic therapy improved rapidly after receiving IVIG.&nbsp;<\/p>\n\n\n\n<p>This result corroborates an earlier finding in which researchers noted that IVIG as an adjunct to antibiotics or surgery dramatically improved the outcome [<a href=\"https:\/\/accpjournals.onlinelibrary.wiley.com\/doi\/10.1592\/phco.19.13.1094.31589\">3<\/a>].&nbsp;<\/p>\n\n\n\n<p>According to the authors of this study, starting IVIG within 24 to 48 hours after the diagnosis could help prevent shock and multiple organ failure.&nbsp;<\/p>\n\n\n\n<p>In a 2017 analysis, researchers analyzed over 4,000 cases of necrotizing fasciitis. Of them, 164 patients received IVIG therapy. They concluded that IVIG had no effect on death or length of hospital stay [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5850528\/\">4<\/a>].<\/p>\n\n\n\n<p>The World Society of Emergency Surgery (WSES) guidelines recommend IVIG for necrotizing soft tissue infections caused by Streptococci and Staphylococci [<a href=\"https:\/\/wjes.biomedcentral.com\/articles\/10.1186\/1749-7922-9-57\">5<\/a>]. The recommendation is based on the potential of IVIG to neutralize bacterial toxins.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-1202e769eb4d0edc2c624c6ca92c6566\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Your IVIG Dose\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAt-Home Infusion\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_for_Toxic_Necrotizing_Fasciitis_Understanding_the_Mechanism\"><\/span>IVIG for Toxic Necrotizing Fasciitis: Understanding the Mechanism<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>How IVIG benefits people with necrotizing fasciitis isn\u2019t fully understood. Health experts believe IVIG may work by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neutralizing the bacterial toxins<\/li>\n\n\n\n<li>Preventing abnormally rapid multiplication of certain immune cells<\/li>\n\n\n\n<li>Reducing inflammation\u00a0<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_for_Toxic_Necrotizing_Fasciitis_The_Challenges_Ahead\"><\/span>IVIG for Toxic Necrotizing Fasciitis: The Challenges Ahead<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Despite promising results in case studies, several challenges still limit IVIG use for necrotizing fasciitis.&nbsp;<\/p>\n\n\n\n<p>Researchers have yet to determine:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The most effective IVIG agent<\/li>\n\n\n\n<li>The timing of therapy<\/li>\n\n\n\n<li>The dose<\/li>\n\n\n\n<li>The duration of treatment<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_for_Toxic_Necrotizing_Fasciitis_Frequently_Asked_Questions\"><\/span>IVIG for Toxic Necrotizing Fasciitis: Frequently Asked Questions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">What is the role of IVIG in toxic shock syndrome?<\/h4>\n\n\n\n<p>IVIG can be used as an adjunct to surgery and antibiotics to improve survival in people with toxic shock syndrome.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What is the most effective treatment for necrotizing fasciitis?<\/h4>\n\n\n\n<p>Antibiotic therapy and surgery to remove dead tissue are the most effective treatments for necrotizing fasciitis.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">What is the drug of choice for necrotizing fasciitis?<\/h4>\n\n\n\n<p><a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/ceftriaxone-injection-route\/description\/drg-20073123#:~:text=Ceftriaxone%20belongs%20to%20the%20class,only%20with%20your%20doctor's%20prescription.\">Ceftriaxone<\/a> \u2014 a third-generation cephalosporin \u2014 is the drug of choice for early treatment. This medication is effective against gram-negative bacteria but has less potent gram-positive activity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0110i\u1ec1u tr\u1ecb b\u1eb1ng IVIG c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn cho vi\u00eam c\u00e2n ho\u1ea1i t\u1eed nhi\u1ec5m \u0111\u1ed9c trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p. M\u1eb7c d\u00f9 m\u1ed9t v\u00e0i nghi\u00ean c\u1ee9u cho th\u1ea5y l\u1ee3i \u00edch, vi\u1ec7c s\u1eed d\u1ee5ng n\u00f3 v\u1eabn c\u00f2n g\u00e2y tranh c\u00e3i. Vi\u00eam c\u00e2n ho\u1ea1i t\u1eed l\u00e0 m\u1ed9t b\u1ec7nh nhi\u1ec5m tr\u00f9ng do vi khu\u1ea9n hi\u1ebfm g\u1eb7p v\u00e0 ti\u1ebfn tri\u1ec3n nhanh. \u0110i\u1ec1u tr\u1ecb ch\u1eadm tr\u1ec5 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn suy \u0111a t\u1ea1ng v\u00e0 t\u1eed vong.<\/p>","protected":false},"author":25,"featured_media":26572,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[31],"class_list":["post-26571","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig","tag-dr-mark-alfonso"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IVIG for Toxic Necrotizing Fasciitis: What the Evidence Says - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn how IVIG may help with toxic necrotizing fasciitis. 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Trong th\u1eddi gian r\u1ea3nh r\u1ed7i, \u00f4ng th\u00edch \u0111\u1ecdc s\u00e1ch v\u00e0 ch\u1ea1y b\u1ed9.","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/mark-alfonso\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-300x200.jpg",300,200,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-768x512.jpg",768,512,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false]},"uagb_author_info":{"display_name":"Dr. Mark Alfonso, PharmD, BCMTMS","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/mark-alfonso\/"},"uagb_comment_info":0,"uagb_excerpt":"IVIG for toxic necrotizing fasciitis may be an option in certain cases. 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Delayed treatment may result in multiple organ failure and death.","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-300x200.jpg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-nurse.jpg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Mark Alfonso, PharmD, BCMTMS","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/mark-alfonso\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/ivig\/\" rel=\"category tag\">IVIG<\/a>","rttpg_excerpt":"IVIG for toxic necrotizing fasciitis may be an option in certain cases. While a few studies show benefits, its use is controversial. Necrotizing fasciitis is a rare, aggressive bacterial infection. 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