{"id":26502,"date":"2024-09-03T15:50:59","date_gmt":"2024-09-03T22:50:59","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26502"},"modified":"2024-09-17T14:32:36","modified_gmt":"2024-09-17T21:32:36","slug":"ivig-for-stevens-johnson-syndrome-sjs","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/","title":{"rendered":"IVIG cho h\u1ed9i ch\u1ee9ng Stevens-Johnson (SJS)"},"content":{"rendered":"<p>N\u1ebfu b\u1ea1n th\u1ea5y ph\u00e1t ban, ph\u1ed3ng r\u1ed9p ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng tr\u00ean da sau khi d\u00f9ng m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c nh\u1ea5t \u0111\u1ecbnh, b\u1ea1n n\u00ean \u0111i kh\u00e1m ngay l\u1eadp t\u1ee9c v\u00ec \u0111\u00e2y l\u00e0 nh\u1eefng d\u1ea5u hi\u1ec7u \u0111\u00e1ng b\u00e1o \u0111\u1ed9ng c\u1ee7a m\u1ed9t ch\u1ee9ng r\u1ed1i lo\u1ea1n da c\u1ea5p t\u00ednh, hi\u1ebfm g\u1eb7p v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u1eed vong \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 h\u1ed9i ch\u1ee9ng Stevens-Johnson hay SJS.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-4951b366abf53d90efaeb0cf1085925c\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 cho ph\u00e9p tr\u01b0\u1edbc c\u1ee7a IVIG\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>H\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng da hi\u1ebfm g\u1eb7p nh\u01b0ng nghi\u00eam tr\u1ecdng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kho\u1ea3ng <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459323\/#:~:text=The%20drugs%20that%20most%20commonly,Sulfonamides%3A%20cotrimoxazole%2C%20sulfasalazine\">hai \u0111\u1ebfn b\u1ea3y ng\u01b0\u1eddi trong m\u1ed9t tri\u1ec7u<\/a> h\u00e0ng n\u0103m. M\u1ed7i n\u0103m, c\u00f3 kho\u1ea3ng 300 tr\u01b0\u1eddng h\u1ee3p m\u1eafc SJS m\u1edbi \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o t\u1ea1i Hoa K\u1ef3.<\/p>\n\n\n\n<p>Trong s\u1ed1 c\u00e1c l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb cho SJS, <a href=\"https:\/\/www.aai.org.tr\/abstract.php?id=280\">Li\u1ec7u ph\u00e1p IVIG \u0111\u01b0\u1ee3c coi l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn hi\u1ec7u qu\u1ea3<\/a> \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng da nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng n\u00e0y.&nbsp;<\/p>\n\n\n\n<p>B\u00e0i vi\u1ebft n\u00e0y th\u1ea3o lu\u1eadn v\u1ec1 h\u1ed9i ch\u1ee9ng Stevens-Johnson, c\u00e1ch th\u1ee9c di\u1ec5n ra v\u00e0 c\u00e1ch IVIG c\u00f3 th\u1ec3 gi\u00fap \u00edch.<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#What_Is_Stevens-Johnson_Syndrome\" >H\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#What_Causes_Stevens-Johnson_Syndrome\" >Nguy\u00ean nh\u00e2n g\u00e2y ra h\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#How_Does_IVIG_Therapy_Work_in_Patients_With_SJS\" >Li\u1ec7u ph\u00e1p IVIG ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o \u1edf b\u1ec7nh nh\u00e2n m\u1eafc SJS?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#Working_Mechanism_of_IVIG_Therapy\" >C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a li\u1ec7u ph\u00e1p IVIG<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#How_Long_Is_IVIG_Therapy_Given_to_Patients_With_Stevens-Johnson_Syndrome\" >Li\u1ec7u ph\u00e1p IVIG \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson trong bao l\u00e2u?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#Can_IVIG_Cause_Any_Side_Effects_in_Patients_With_Stevens-Johnson_Syndrome\" >IVIG c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o \u1edf b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson kh\u00f4ng?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#What_Is_the_Recommended_Dosage_of_IVIG_for_Stevens-Johnson_Syndrome\" >Li\u1ec1u l\u01b0\u1ee3ng IVIG khuy\u1ebfn c\u00e1o cho h\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 bao nhi\u00eau?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-stevens-johnson-syndrome-sjs\/#Summary\" >B\u1ea3n t\u00f3m t\u1eaft<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Stevens-Johnson_Syndrome\"><\/span><strong>H\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>H\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng hi\u1ebfm g\u1eb7p v\u00e0 \u0111e d\u1ecda t\u00ednh m\u1ea1ng, \u1ea3nh h\u01b0\u1edfng nghi\u00eam tr\u1ecdng \u0111\u1ebfn da v\u00e0 ni\u00eam m\u1ea1c. H\u1ed9i ch\u1ee9ng n\u00e0y th\u01b0\u1eddng do m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c nh\u1ea5t \u0111\u1ecbnh (trong h\u01a1n 801 tr\u01b0\u1eddng h\u1ee3p) ho\u1eb7c nhi\u1ec5m tr\u00f9ng (virus ho\u1eb7c mycoplasma pneumoniae) g\u00e2y ra.&nbsp;<\/p>\n\n\n\n<p>H\u1ed9i ch\u1ee9ng SJS b\u1eaft \u0111\u1ea7u v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng gi\u1ed1ng c\u00fam, bao g\u1ed3m s\u1ed1t, \u0111au h\u1ecdng v\u00e0 m\u1ec7t m\u1ecfi. Trong v\u00f2ng v\u00e0i ng\u00e0y, c\u00e1c \u0111\u1ed1m \u0111\u1ecf ho\u1eb7c t\u00edm xu\u1ea5t hi\u1ec7n tr\u00ean da. Cu\u1ed1i c\u00f9ng, da xung quanh c\u00e1c \u0111\u1ed1m n\u00e0y bong tr\u00f3c th\u00e0nh t\u1eebng m\u1ea3ng v\u00e0 c\u00e1c m\u1ee5n n\u01b0\u1edbc v\u1ee1 ra. H\u01a1n n\u1eefa, ni\u00eam m\u1ea1c mi\u1ec7ng, m\u1eaft v\u00e0 b\u1ed9 ph\u1eadn sinh d\u1ee5c c\u0169ng b\u1ecb \u1ea3nh h\u01b0\u1edfng v\u00e0 d\u1eabn \u0111\u1ebfn lo\u00e9t \u0111au \u0111\u1edbn.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Causes_Stevens-Johnson_Syndrome\"><\/span><strong>Nguy\u00ean nh\u00e2n g\u00e2y ra h\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u0110\u1ed9t bi\u1ebfn gen HLA-B \u0111\u01b0\u1ee3c coi l\u00e0 nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra h\u1ed9i ch\u1ee9ng Stevens-Johnson. Gen n\u00e0y l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a ph\u1ee9c h\u1ee3p kh\u00e1ng nguy\u00ean b\u1ea1ch c\u1ea7u ng\u01b0\u1eddi (HLA), gi\u00fap h\u1ec7 mi\u1ec5n d\u1ecbch ph\u00e2n bi\u1ec7t gi\u1eefa protein do c\u01a1 th\u1ec3 t\u1ea1o ra v\u00e0 protein do c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh nh\u01b0 vi khu\u1ea9n v\u00e0 vi-r\u00fat t\u1ea1o ra.&nbsp;<\/p>\n\n\n\n<p>C\u00e1c nghi\u00ean c\u1ee9u b\u00e1o c\u00e1o r\u1eb1ng c\u00e1c bi\u1ebfn th\u1ec3 trong gen HLA khi\u1ebfn h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch ph\u1ea3n \u1ee9ng b\u1ea5t th\u01b0\u1eddng v\u1edbi m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c nh\u1ea5t \u0111\u1ecbnh (v\u00ed d\u1ee5, thu\u1ed1c ch\u1ed1ng co gi\u1eadt, allopurinol, sulfonamid, nevirapine, NSAID, carbamazepine, v.v.) v\u00e0 g\u00e2y ra s\u1ef1 ph\u00e1 h\u1ee7y c\u00e1c t\u1ebf b\u00e0o (t\u1ebf b\u00e0o s\u1eebng) trong da v\u00e0 ni\u00eam m\u1ea1c.&nbsp;<\/p>\n\n\n\n<p>C\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch, \u0111\u1eb7c bi\u1ec7t l\u00e0 t\u1ebf b\u00e0o T g\u00e2y \u0111\u1ed9c v\u00e0 t\u1ebf b\u00e0o s\u00e1t th\u1ee7 t\u1ef1 nhi\u00ean (NK), gi\u1ea3i ph\u00f3ng granulysin, m\u1ed9t ch\u1ea5t ph\u00e1 h\u1ee7y c\u00e1c t\u1ebf b\u00e0o da v\u00e0 ni\u00eam m\u1ea1c, g\u00e2y ph\u1ed3ng r\u1ed9p v\u00e0 bong tr\u00f3c.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_IVIG_Therapy_Work_in_Patients_With_SJS\"><\/span><strong>Li\u1ec7u ph\u00e1p IVIG ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o \u1edf b\u1ec7nh nh\u00e2n m\u1eafc SJS?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>M\u1ed9t s\u1ed1 <a href=\"https:\/\/www.mdpi.com\/2227-9059\/10\/9\/2105\">nghi\u00ean c\u1ee9u<\/a> \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig\/\/ivig\/\">Li\u1ec7u ph\u00e1p IVIG<\/a> c\u00f3 th\u1ec3 gi\u00fap \u0111i\u1ec1u ch\u1ec9nh ch\u1ee9c n\u0103ng mi\u1ec5n d\u1ecbch, gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong v\u00e0 c\u1ea3i thi\u1ec7n k\u1ebft qu\u1ea3 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson n\u1ebfu b\u1eaft \u0111\u1ea7u s\u1edbm.&nbsp;<\/p>\n\n\n\n<p>V\u00ed d\u1ee5, m\u1ed9t tr\u01b0\u1eddng h\u1ee3p <a href=\"https:\/\/www.elsevier.es\/en-revista-allergologia-et-immunopathologia-105-articulo-use-intravenous-immunoglobulin-for-stevensjohnson-S0301054614001219#:~:text=8%20On%20the%20basis%20of,this%20treatment%20is%20initiated%20early.\">b\u00e1o c\u00e1o<\/a> c\u1ee7a m\u1ed9t b\u1ec7nh nh\u00e2n n\u1eef m\u01b0\u1eddi tu\u1ed5i \u0111\u01b0\u1ee3c d\u00f9ng li\u1ec1u 750 mg\/kg\/ng\u00e0y (4 ng\u00e0y) IVIG, c\u00f9ng v\u1edbi d\u1ecbch truy\u1ec1n t\u0129nh m\u1ea1ch v\u00e0 clindamycin, cho th\u1ea5y t\u00ecnh tr\u1ea1ng c\u1ee7a c\u00f4 b\u00e9 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 m\u00e0 kh\u00f4ng b\u1ecb s\u1ed1t \u0111\u1ed9t ng\u1ed9t v\u00e0 c\u00e1c t\u1ed5n th\u01b0\u01a1ng tr\u00ean da thuy\u00ean gi\u1ea3m sau 8 ng\u00e0y \u0111i\u1ec1u tr\u1ecb.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Working_Mechanism_of_IVIG_Therapy\"><\/span><strong>C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a li\u1ec7u ph\u00e1p IVIG<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>M\u1eb7c d\u00f9 c\u01a1 ch\u1ebf ch\u00ednh x\u00e1c c\u1ee7a li\u1ec7u ph\u00e1p IVIG v\u1eabn ch\u01b0a r\u00f5 r\u00e0ng, nh\u01b0ng ng\u01b0\u1eddi ta cho r\u1eb1ng n\u00f3 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>1. \u1ee8c ch\u1ebf ho\u1ea1t h\u00f3a t\u1ebf b\u00e0o T CD8+<\/strong><\/h4>\n\n\n\n<p>V\u00ec s\u1ef1 k\u00edch ho\u1ea1t c\u1ee7a t\u1ebf b\u00e0o T g\u00e2y \u0111\u1ed9c t\u1ebf b\u00e0o CD8+ v\u00e0 t\u1ebf b\u00e0o NK g\u00e2y ra s\u1ef1 ph\u00e1 h\u1ee7y c\u00e1c t\u1ebf b\u00e0o s\u1eebng \u1edf da v\u00e0 ni\u00eam m\u1ea1c, n\u00ean li\u1ec7u ph\u00e1p IVIG c\u00f3 t\u00e1c d\u1ee5ng <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5130247\/\">m\u1ea1nh m\u1ebd \u0111\u00e0n \u00e1p<\/a> s\u1ef1 k\u00edch ho\u1ea1t c\u1ee7a ch\u00fang, d\u1eabn \u0111\u1ebfn gi\u1ea3m ph\u1ea3n \u1ee9ng v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n thu\u1ed1c.&nbsp;<\/p>\n\n\n\n<p>H\u01a1n n\u1eefa, IVIG c\u0169ng <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5130247\/\">l\u00e0m gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o NK trong m\u00e1u v\u00e0 m\u1ee9c \u0111\u1ed9 granzyme B<\/a> (m\u1ed9t lo\u1ea1i enzyme c\u00f3 trong c\u00e1c h\u1ea1t c\u1ee7a t\u1ebf b\u00e0o NK v\u00e0 t\u1ebf b\u00e0o T g\u00e2y \u0111\u1ed9c, c\u00f3 t\u00e1c d\u1ee5ng ph\u00e1 h\u1ee7y t\u1ebf b\u00e0o s\u1eebng). Do \u0111\u00f3, IVIG ng\u0103n ng\u1eeba m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a b\u1ec7nh b\u1eb1ng c\u00e1ch gi\u1ea3m l\u01b0\u1ee3ng granzyme B trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>2. Gi\u1ea3m vi\u00eam<\/strong><\/h4>\n\n\n\n<p>T\u00ednh ch\u1ea5t ch\u1ed1ng vi\u00eam c\u1ee7a li\u1ec7u ph\u00e1p IVIG l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng vi\u00eam v\u00e0 ng\u0103n ng\u1eeba t\u1ed5n th\u01b0\u01a1ng da v\u00e0 ni\u00eam m\u1ea1c do vi\u00eam \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>3. Th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh ch\u1eefa l\u00e0nh v\u1ebft th\u01b0\u01a1ng<\/strong><\/h4>\n\n\n\n<p>C\u00e1c kh\u00e1ng th\u1ec3 \u0111\u01b0\u1ee3c cung c\u1ea5p b\u1edfi li\u1ec7u ph\u00e1p IVIG <a href=\"https:\/\/www.frontiersin.org\/journals\/medicine\/articles\/10.3389\/fmed.2021.636924\/full\">th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh ch\u1eefa l\u00e0nh v\u1ebft th\u01b0\u01a1ng nhanh ch\u00f3ng<\/a> \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson. H\u01a1n n\u1eefa, m\u1ed9t s\u1ed1 <a href=\"https:\/\/www.jle.com\/fr\/revues\/ejd\/e-docs\/high_dose_intravenous_immunoglobulins_in_the_treatment_of_stevens_johnson_syndrome_and_toxic_epidermal_necrolysis_in_chinese_pa_286613\/article.phtml?cle_doc=00045F95&amp;cle_doc=00045F95\">nghi\u00ean c\u1ee9u<\/a> \u0111\u1ec1 xu\u1ea5t r\u1eb1ng IVIG k\u1ebft h\u1ee3p v\u1edbi corticosteroid \u0111\u00e3 l\u00e0m gi\u1ea3m th\u1eddi gian ph\u1ee5c h\u1ed3i \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson.&nbsp;<\/p>\n\n\n\n<p>Ngo\u00e0i ra, li\u1ec7u ph\u00e1p IVIG c\u0169ng <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/ijd.12423\">gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong<\/a> \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng IVIG (li\u1ec1u \u22652 g\/kg) so v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00e1c kh\u00f4ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng IVIG.<\/p>\n\n\n\n<div  id=\"call-to-action-2be4219915b86a361281d4cc06bbc4f0\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">L\u00ean l\u1ecbch t\u01b0 v\u1ea5n<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Long_Is_IVIG_Therapy_Given_to_Patients_With_Stevens-Johnson_Syndrome\"><\/span><strong>Li\u1ec7u ph\u00e1p IVIG \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson trong bao l\u00e2u?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb IVIG \u1edf b\u1ec7nh nh\u00e2n SJS ph\u1ee5 thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh. Th\u00f4ng th\u01b0\u1eddng, IVIG \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng trong giai \u0111o\u1ea1n n\u1eb7ng c\u1ee7a SJS, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c, v\u00e0 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c truy\u1ec1n IVIG h\u00e0ng ng\u00e0y trong 3 \u0111\u1ebfn 5 ng\u00e0y.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_IVIG_Cause_Any_Side_Effects_in_Patients_With_Stevens-Johnson_Syndrome\"><\/span><strong>IVIG c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o \u1edf b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson kh\u00f4ng?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ec7nh nh\u00e2n m\u1eafc SJS c\u00f3 th\u1ec3 g\u1eb7p m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 khi truy\u1ec1n IVIG. M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p bao g\u1ed3m ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, bu\u1ed3n n\u00f4n, \u0111au \u0111\u1ea7u, \u1edbn l\u1ea1nh ho\u1eb7c s\u1ed1t.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_the_Recommended_Dosage_of_IVIG_for_Stevens-Johnson_Syndrome\"><\/span><strong>Li\u1ec1u l\u01b0\u1ee3ng IVIG khuy\u1ebfn c\u00e1o cho h\u1ed9i ch\u1ee9ng Stevens-Johnson l\u00e0 bao nhi\u00eau?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o c\u1ee7a IVIG cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Stevens-Johnson v\u00e0 c\u00f3 SCORTEN (thang \u0111i\u1ec3m x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a t\u00ecnh tr\u1ea1ng da) cao h\u01a1n 0 l\u00e0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20952352\/\">2 \u2013 3 g\/kg<\/a>, \u0111\u01b0\u1ee3c d\u00f9ng trong v\u00f2ng 2 \u2013 3 ng\u00e0y, t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Summary\"><\/span><strong>B\u1ea3n t\u00f3m t\u1eaft<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>H\u1ed9i ch\u1ee9ng Stevens-Johnson (SJS) l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd da nghi\u00eam tr\u1ecdng g\u00e2y ph\u00e1t ban v\u00e0 ph\u1ed3ng r\u1ed9p \u0111au \u0111\u1edbn tr\u00ean da v\u00e0 ni\u00eam m\u1ea1c. Ph\u1ea3n \u1ee9ng da n\u00e0y l\u00e0 do ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch qua trung gian thu\u1ed1c nh\u1eafm v\u00e0o v\u00e0 ti\u00eau di\u1ec7t c\u00e1c t\u1ebf b\u00e0o s\u1eebng (t\u1ebf b\u00e0o hi\u1ec7n di\u1ec7n trong l\u1edbp bi\u1ec3u b\u00ec). Li\u1ec7u ph\u00e1p IVIG \u0111\u01b0\u1ee3c coi l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7y h\u1ee9a h\u1eb9n cho SJS v\u00e0 gi\u00fap l\u00e0m d\u1ecbu ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch ho\u1ea1t \u0111\u1ed9ng b\u1ea5t th\u01b0\u1eddng \u1edf b\u1ec7nh nh\u00e2n SJS.&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>N\u1ebfu b\u1ea1n th\u1ea5y ph\u00e1t ban, ph\u1ed3ng r\u1ed9p ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng tr\u00ean da sau khi d\u00f9ng m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c nh\u1ea5t \u0111\u1ecbnh, b\u1ea1n n\u00ean \u0111i kh\u00e1m ngay l\u1eadp t\u1ee9c v\u00ec \u0111\u00e2y l\u00e0 nh\u1eefng d\u1ea5u hi\u1ec7u \u0111\u00e1ng b\u00e1o \u0111\u1ed9ng c\u1ee7a m\u1ed9t ch\u1ee9ng r\u1ed1i lo\u1ea1n da c\u1ea5p t\u00ednh, hi\u1ebfm g\u1eb7p v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u1eed vong \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 h\u1ed9i ch\u1ee9ng Stevens-Johnson hay SJS.\u00a0<\/p>","protected":false},"author":25,"featured_media":26503,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[31],"class_list":["post-26502","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig","tag-dr-mark-alfonso"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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Ph\u1ea7n b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a \u00f4ng l\u00e0 gi\u00fap tr\u1ea3 l\u1eddi c\u00e1c c\u00e2u h\u1ecfi v\u00e0 m\u1ed1i quan t\u00e2m c\u1ee7a b\u1ec7nh nh\u00e2n. C\u00e1c l\u0129nh v\u1ef1c chuy\u00ean m\u00f4n c\u1ee7a \u00f4ng l\u00e0 qu\u1ea3n l\u00fd d\u01b0\u1ee3c ph\u1ea9m c\u1ed9ng \u0111\u1ed3ng v\u00e0 li\u1ec7u ph\u00e1p thu\u1ed1c. 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b\u1ed9.","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/mark-alfonso\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-300x200.jpg",300,200,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-768x512.jpg",768,512,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/09\/ivig.jpg",1280,853,false]},"uagb_author_info":{"display_name":"Dr. 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