{"id":26368,"date":"2024-07-29T15:49:01","date_gmt":"2024-07-29T22:49:01","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26368"},"modified":"2024-07-29T15:49:04","modified_gmt":"2024-07-29T22:49:04","slug":"krystexxa-a-treatment-for-chronic-gout","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/","title":{"rendered":"Krystexxa: Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00fat m\u00e3n t\u00ednh"},"content":{"rendered":"<p>Krystexxa, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi b\u1eb1ng t\u00ean chung l\u00e0 \u201cpegloticase\u201d, l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ti\u00eam \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh m\u00e3n t\u00ednh, kh\u00f3 \u0111i\u1ec1u tr\u1ecb, nghi\u00eam tr\u1ecdng <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/gout\/symptoms-causes\/syc-20372897\">b\u1ec7nh gout<\/a> \u1edf ng\u01b0\u1eddi l\u1edbn kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00fat th\u00f4ng th\u01b0\u1eddng.\u00a0<\/p>\n\n\n\n<div  id=\"call-to-action-fb779daadd5432c228b00a9e6ee71e1e\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tN\u00f3i chuy\u1ec7n v\u1edbi m\u1ed9t chuy\u00ean gia\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tV\u1ec1 Tr\u1ee3 c\u1ea5p \u0111\u1ed3ng thanh to\u00e1n\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>Krystexxa thu\u1ed9c nh\u00f3m thu\u1ed1c \u201cthu\u1ed1c ch\u1ed1ng t\u0103ng axit uric m\u00e1u ho\u1eb7c thu\u1ed1c ch\u1ed1ng g\u00fat\u201d, c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng s\u1ea3n xu\u1ea5t qu\u00e1 m\u1ee9c axit uric \u1edf b\u1ec7nh nh\u00e2n g\u00fat. Thu\u1ed1c n\u00e0y l\u1ea7n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t b\u1edfi <a href=\"https:\/\/www.fda.gov\/\">FDA<\/a> v\u00e0o n\u0103m 2010 d\u1ef1a tr\u00ean k\u1ebft qu\u1ea3 c\u1ee7a hai <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21846852\/\">th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng<\/a>.&nbsp;<\/p>\n\n\n\n<p>Krystexxa ch\u1ec9 \u0111\u01b0\u1ee3c b\u00e1n theo \u0111\u01a1n.&nbsp;<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#What_Is_Krystexxa_Used_To_Treat\" >Thu\u1ed1c Krystexxa \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#When_Is_Krystexxa_Prescribed_to_Gout_Patients\" >Khi n\u00e0o thu\u1ed1c Krystexxa \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n cho b\u1ec7nh nh\u00e2n g\u00fat?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#How_Does_Krystexxa_Work\" >Krystexxa ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#Can_Krystexxa_Be_Used_in_Patients_with_Hyperuricemia\" >Thu\u1ed1c Krystexxa c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n t\u0103ng axit uric m\u00e1u kh\u00f4ng?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#In_What_Pharmaceutical_Form_Is_Krystexxa_Available_and_Supplied\" >Krystexxa \u0111\u01b0\u1ee3c cung c\u1ea5p v\u00e0 s\u1eed d\u1ee5ng \u1edf d\u1ea1ng b\u00e0o ch\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#What_Is_the_Recommended_Dose_for_Adult_Gout_Patients\" >Li\u1ec1u d\u00f9ng khuy\u1ebfn c\u00e1o cho b\u1ec7nh nh\u00e2n g\u00fat tr\u01b0\u1edfng th\u00e0nh l\u00e0 bao nhi\u00eau?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#How_Is_Krystexxa_Given\" >Krystexxa \u0111\u01b0\u1ee3c cung c\u1ea5p nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#What_Are_the_Common_Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#How_Long_Is_Krystexxa_Therapy\" >Li\u1ec7u tr\u00ecnh Krystexxa k\u00e9o d\u00e0i bao l\u00e2u?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#What_Special_Precautions_Should_You_Follow\" >B\u1ea1n n\u00ean tu\u00e2n th\u1ee7 nh\u1eefng bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba \u0111\u1eb7c bi\u1ec7t n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#What_Drugs_Should_You_Avoid_While_Taking_Krystexxa\" >B\u1ea1n n\u00ean tr\u00e1nh nh\u1eefng lo\u1ea1i thu\u1ed1c n\u00e0o khi d\u00f9ng Krystexxa?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#Who_Should_Not_Take_Krystexxa\" >Ai kh\u00f4ng n\u00ean d\u00f9ng Krystexxa?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/krystexxa-a-treatment-for-chronic-gout\/#Cost\" >Tr\u1ecb gi\u00e1<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Krystexxa_Used_To_Treat\"><\/span><strong>Thu\u1ed1c Krystexxa \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>FDA \u0111\u00e3 ph\u00ea duy\u1ec7t Krystexxa \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00fat m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn. G\u00fat l\u00e0 m\u1ed9t lo\u1ea1i vi\u00eam kh\u1edbp x\u1ea3y ra do n\u1ed3ng \u0111\u1ed9 axit uric trong c\u01a1 th\u1ec3 cao b\u1ea5t th\u01b0\u1eddng. Khi n\u1ed3ng \u0111\u1ed9 axit uric cao t\u00edch t\u1ee5 trong m\u00e1u ho\u1eb7c d\u1ecbch quanh kh\u1edbp, n\u00f3 s\u1ebd chuy\u1ec3n h\u00f3a th\u00e0nh tinh th\u1ec3 axit uric, g\u00e2y \u0111au d\u1eef d\u1ed9i, \u0111\u1ecf v\u00e0 s\u01b0ng kh\u1edbp.&nbsp;<\/p>\n\n\n\n<p>Theo th\u1eddi gian, c\u00e1c tinh th\u1ec3 axit uric h\u00ecnh th\u00e0nh c\u00e1c kh\u1ed1i u m\u00e0u tr\u1eafng xung quanh kh\u1edbp v\u00e0 m\u00f4 m\u1ec1m (g\u1ecdi l\u00e0 tophi), th\u01b0\u1eddng l\u1ed9 r\u00f5 d\u01b0\u1edbi da v\u00e0 tr\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c n\u1ed1t s\u01b0ng. \u0110i\u1ec1u n\u00e0y c\u00e0ng l\u00e0m t\u1ed5n th\u01b0\u01a1ng kh\u1edbp, d\u1eabn \u0111\u1ebfn m\u1ea5t kh\u1ea3 n\u0103ng v\u1eadn \u0111\u1ed9ng.&nbsp;<\/p>\n\n\n\n<p>B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh g\u00fat m\u00e3n t\u00ednh th\u01b0\u1eddng xuy\u00ean b\u1ecb \u0111au d\u1eef d\u1ed9i v\u00e0 vi\u00eam \u1edf nhi\u1ec1u kh\u1edbp, c\u00f2n g\u1ecdi l\u00e0 c\u01a1n g\u00fat.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"When_Is_Krystexxa_Prescribed_to_Gout_Patients\"><\/span><strong>Khi n\u00e0o thu\u1ed1c Krystexxa \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n cho b\u1ec7nh nh\u00e2n g\u00fat?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Krystexxa th\u01b0\u1eddng \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n nh\u01b0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb tuy\u1ebfn ba v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ri\u00eang l\u1ebb ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682019.html\">methotrexate<\/a> \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh g\u00fat m\u00e3n t\u00ednh trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Khi c\u00e1c lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb g\u00fat th\u00f4ng th\u01b0\u1eddng kh\u00f4ng hi\u1ec7u qu\u1ea3 ho\u1eb7c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n. M\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb g\u00fat th\u01b0\u1eddng \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n bao g\u1ed3m thu\u1ed1c \u1ee9c ch\u1ebf xanthine oxidase, allopurinol, febuxostat v\u00e0 probenecid.<\/li>\n\n\n\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau v\u1ec1 axit uric huy\u1ebft thanh.<\/li>\n\n\n\n<li>B\u1ec7nh nh\u00e2n ti\u1ebfp t\u1ee5c b\u1ecb c\u00e1c \u0111\u1ee3t b\u00f9ng ph\u00e1t b\u1ec7nh g\u00fat th\u01b0\u1eddng xuy\u00ean (\u22652 \u0111\u1ee3t b\u00f9ng ph\u00e1t\/n\u0103m).<\/li>\n\n\n\n<li>B\u1ec7nh nh\u00e2n c\u00f3 c\u1ee5c u d\u01b0\u1edbi da kh\u00f4ng t\u1ef1 kh\u1ecfi.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_Krystexxa_Work\"><\/span><strong>Krystexxa ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Ho\u1ea1t ch\u1ea5t trong Krystexxa, pegloticase, ch\u1ee9a m\u1ed9t lo\u1ea1i enzyme g\u1ecdi l\u00e0 uricase, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p c\u00f4ng ngh\u1ec7 DNA t\u00e1i t\u1ed5 h\u1ee3p trong ph\u00f2ng th\u00ed nghi\u1ec7m. Enzyme uricase ph\u00e2n h\u1ee7y c\u00e1c tinh th\u1ec3 axit uric (tinh th\u1ec3) th\u00e0nh c\u00e1c ch\u1ea5t d\u1ec5 h\u00f2a tan h\u01a1n (allantoin), sau \u0111\u00f3 \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ra kh\u1ecfi c\u01a1 th\u1ec3 qua n\u01b0\u1edbc ti\u1ec3u.&nbsp;<\/p>\n\n\n\n<p>Khi n\u1ed3ng \u0111\u1ed9 axit uric gi\u1ea3m xu\u1ed1ng d\u01b0\u1edbi 6 mg\/dl, c\u00e1c tinh th\u1ec3 trong kh\u1edbp b\u1eaft \u0111\u1ea7u tan ra, l\u00e0m c\u00e1c h\u1ea1t tophi co l\u1ea1i d\u1ea7n.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_Krystexxa_Be_Used_in_Patients_with_Hyperuricemia\"><\/span><strong>Thu\u1ed1c Krystexxa c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n t\u0103ng axit uric m\u00e1u kh\u00f4ng?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Theo h\u01b0\u1edbng d\u1eabn c\u1ee7a FDA, Krystexxa kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng axit uric m\u00e1u (t\u00ecnh tr\u1ea1ng m\u00f4 t\u1ea3 m\u1ee9c axit uric cao) \u1edf nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng b\u1ec7nh g\u00fat li\u00ean quan.&nbsp;<\/p>\n\n\n\n<p>Nh\u00ecn chung, nh\u1eefng ng\u01b0\u1eddi b\u1ecb t\u0103ng axit uric m\u00e1u c\u00f3 th\u1ec3 d\u00f9ng c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c \u0111\u1ec3 h\u1ea1 n\u1ed3ng \u0111\u1ed9 axit uric trong c\u01a1 th\u1ec3. Tuy nhi\u00ean, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7918342\/\">t\u0103ng axit uric m\u00e1u c\u00f3 th\u1ec3 tr\u1edf th\u00e0nh y\u1ebfu t\u1ed1 nguy c\u01a1 g\u00e2y b\u1ec7nh g\u00fat<\/a> n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi.&nbsp;<\/p>\n\n\n\n<p>\u0110\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi b\u1ecb b\u1ec7nh g\u00fat m\u00e3n t\u00ednh, khi kh\u00f4ng c\u00f3 lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb g\u00fat th\u00f4ng th\u01b0\u1eddng n\u00e0o c\u00f3 hi\u1ec7u qu\u1ea3, Krystexxa \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb c\u1ee5 th\u1ec3 l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1eadc ba \u0111\u1ec3 h\u1ea1 th\u1ea5p n\u1ed3ng \u0111\u1ed9 axit uric \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y.&nbsp;<\/p>\n\n\n\n<p>T\u00f3m l\u1ea1i, lo\u1ea1i thu\u1ed1c n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng chung cho m\u1ecdi tr\u01b0\u1eddng h\u1ee3p t\u0103ng axit uric m\u00e1u.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"In_What_Pharmaceutical_Form_Is_Krystexxa_Available_and_Supplied\"><\/span><strong>Krystexxa \u0111\u01b0\u1ee3c cung c\u1ea5p v\u00e0 s\u1eed d\u1ee5ng \u1edf d\u1ea1ng b\u00e0o ch\u1ebf n\u00e0o?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Krystexxa c\u00f3 d\u1ea1ng dung d\u1ecbch pegloticase trong su\u1ed1t, v\u00f4 tr\u00f9ng, h\u00e0m l\u01b0\u1ee3ng 8 mg\/ml v\u00e0 \u0111\u01b0\u1ee3c cung c\u1ea5p trong l\u1ecd li\u1ec1u \u0111\u01a1n.&nbsp;<\/p>\n\n\n\n<p>Dung d\u1ecbch \u0111\u01b0\u1ee3c pha lo\u00e3ng (tr\u1ed9n) v\u1edbi t\u00fai 250 ml ch\u1ee9a 0,9% natri clorua tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_the_Recommended_Dose_for_Adult_Gout_Patients\"><\/span><strong>Li\u1ec1u d\u00f9ng khuy\u1ebfn c\u00e1o cho b\u1ec7nh nh\u00e2n g\u00fat tr\u01b0\u1edfng th\u00e0nh l\u00e0 bao nhi\u00eau?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Li\u1ec1u d\u00f9ng khuy\u1ebfn c\u00e1o c\u1ee7a Krystexxa cho ng\u01b0\u1eddi l\u1edbn b\u1ecb b\u1ec7nh g\u00fat m\u00e3n t\u00ednh l\u00e0 8 mg, n\u00ean d\u00f9ng 1 l\u1ea7n m\u1ed7i 2 tu\u1ea7n.\u00a0<\/p>\n\n\n\n<div  id=\"call-to-action-374ca2acc571ce3486da940143b07430\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">L\u00ean l\u1ecbch t\u01b0 v\u1ea5n<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Krystexxa_Given\"><\/span><strong>Krystexxa \u0111\u01b0\u1ee3c cung c\u1ea5p nh\u01b0 th\u1ebf n\u00e0o?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Krystexxa \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o d\u00f9ng ri\u00eang ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi methotrexate d\u01b0\u1edbi d\u1ea1ng truy\u1ec1n t\u0129nh m\u1ea1ch trong th\u1eddi gian kh\u00f4ng d\u01b0\u1edbi 120 ph\u00fat qua b\u01a1m ti\u00eam truy\u1ec1n. Nh\u00e2n vi\u00ean y t\u1ebf s\u1ebd ti\u00eam thu\u1ed1c v\u00e0o t\u0129nh m\u1ea1ch.&nbsp;<\/p>\n\n\n\n<p>Nh\u1eefng \u0111i\u1ec1u quan tr\u1ecdng kh\u00e1c c\u1ea7n l\u01b0u \u00fd:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Krystexxa kh\u00f4ng n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng d\u01b0\u1edbi d\u1ea1ng ti\u00eam t\u0129nh m\u1ea1ch ho\u1eb7c <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/bolus-dose\">vi\u00ean thu\u1ed1c<\/a>.<\/li>\n\n\n\n<li>\u0110\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 ph\u1ea3n \u1ee9ng truy\u1ec1n d\u1ecbch, b\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng thu\u1ed1c tr\u01b0\u1edbc, ch\u1eb3ng h\u1ea1n nh\u01b0 thu\u1ed1c kh\u00e1ng histamine v\u00e0 corticosteroid.\u00a0<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_the_Common_Side_Effects\"><\/span><strong>T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p l\u00e0 g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ea1n c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 sau \u0111\u00e2y sau khi d\u00f9ng d\u1ecbch truy\u1ec1n Krystexxa:&nbsp;&nbsp;<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"278\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain.jpg\" alt=\"Man with chest pains as a side effect of taking Krystexxa\" class=\"wp-image-26374\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain-300x199.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain-280x185.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/chest-pain-370x245.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<ul class=\"wp-block-list\">\n<li>C\u00e1c \u0111\u1ee3t b\u00f9ng ph\u00e1t b\u1ec7nh g\u00fat m\u1edbi (t\u0103ng trong 3 th\u00e1ng \u0111\u1ea7u do n\u1ed3ng \u0111\u1ed9 axit uric huy\u1ebft thanh thay \u0111\u1ed5i v\u00e0 cu\u1ed1i c\u00f9ng gi\u1ea3m trong 3 th\u00e1ng \u0111i\u1ec1u tr\u1ecb ti\u1ebfp theo)<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Bu\u1ed3n n\u00f4n<\/li>\n\n\n\n<li>\u0110au ng\u1ef1c<\/li>\n\n\n\n<li>N\u00f4n m\u1eeda<\/li>\n\n\n\n<li>M\u1ec7t m\u1ecfi<\/li>\n\n\n\n<li>\u0110au kh\u1edbp<\/li>\n\n\n\n<li>T\u00e1o b\u00f3n<\/li>\n<\/ul>\n\n\n\n<p>B\u1ea1n c\u0169ng c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng, c\u00f3 th\u1ec3 \u0111e d\u1ecda t\u00ednh m\u1ea1ng v\u00e0 th\u01b0\u1eddng x\u1ea3y ra trong v\u00f2ng 2 gi\u1edd sau khi truy\u1ec1n. Do \u0111\u00f3, khuy\u1ebfn c\u00e1o b\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng thu\u1ed1c kh\u00e1ng histamine v\u00e0 corticosteroid tr\u01b0\u1edbc \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 truy\u1ec1n v\u00e0 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Long_Is_Krystexxa_Therapy\"><\/span><strong>Li\u1ec7u tr\u00ecnh Krystexxa k\u00e9o d\u00e0i bao l\u00e2u?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ec7nh nh\u00e2n th\u01b0\u1eddng th\u1ea5y t\u00ecnh tr\u1ea1ng c\u1ea3i thi\u1ec7n sau 3 th\u00e1ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Krystexxa. Tuy nhi\u00ean, n\u00ean ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb t\u1eeb 6 \u0111\u1ebfn 12 th\u00e1ng ho\u1eb7c theo khuy\u1ebfn c\u00e1o c\u1ee7a b\u00e1c s\u0129.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Special_Precautions_Should_You_Follow\"><\/span><strong>B\u1ea1n n\u00ean tu\u00e2n th\u1ee7 nh\u1eefng bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba \u0111\u1eb7c bi\u1ec7t n\u00e0o?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Tr\u01b0\u1edbc khi d\u00f9ng d\u1ecbch truy\u1ec1n Krystexxa, h\u00e3y cho b\u00e1c s\u0129 bi\u1ebft n\u1ebfu b\u1ea1n:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0110ang mang thai ho\u1eb7c c\u00f3 \u00fd \u0111\u1ecbnh mang thai<\/li>\n\n\n\n<li>\u0110ang cho con b\u00fa ho\u1eb7c c\u00f3 k\u1ebf ho\u1ea1ch cho con b\u00fa<\/li>\n\n\n\n<li>\u0110\u00e3 t\u1eebng m\u1eafc b\u1ea5t k\u1ef3 t\u00ecnh tr\u1ea1ng n\u00e0o nh\u01b0 suy tim, b\u1ec7nh tim ho\u1eb7c t\u0103ng huy\u1ebft \u00e1p (huy\u1ebft \u00e1p cao) ch\u01b0a?<\/li>\n\n\n\n<li>B\u1ecb d\u1ecb \u1ee9ng v\u1edbi pegloticase<\/li>\n\n\n\n<li>\u0110ang d\u00f9ng b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c n\u00e0o nh\u01b0 thu\u1ed1c theo toa v\u00e0 thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n, vitamin v\u00e0 th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng th\u1ea3o d\u01b0\u1ee3c<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Drugs_Should_You_Avoid_While_Taking_Krystexxa\"><\/span><strong>B\u1ea1n n\u00ean tr\u00e1nh nh\u1eefng lo\u1ea1i thu\u1ed1c n\u00e0o khi d\u00f9ng Krystexxa?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ea1n kh\u00f4ng n\u00ean d\u00f9ng c\u00e1c thu\u1ed1c h\u1ea1 axit uric kh\u00e1c trong khi \u0111ang d\u00f9ng Krystexxa v\u00ec ch\u00fang c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n ho\u1eb7c nguy hi\u1ec3m. M\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c h\u1ea1 axit uric b\u1ea1n kh\u00f4ng n\u00ean d\u00f9ng l\u00e0 allopurinol, febuxostat v\u00e0 <a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/probenecid-oral-route\/description\/drg-20065625#:~:text=Probenecid%20is%20used%20in%20the,will%20help%20prevent%20gout%20attacks.\">probenecid<\/a>.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_Should_Not_Take_Krystexxa\"><\/span><strong>Ai kh\u00f4ng n\u00ean d\u00f9ng Krystexxa?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh chuy\u1ec3n h\u00f3a g\u1ecdi l\u00e0 thi\u1ebfu h\u1ee5t glucose-6-phosphate dehydrogenase (G6PD) ho\u1eb7c favism, m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u hi\u1ebfm g\u1eb7p, kh\u00f4ng n\u00ean d\u00f9ng Krystexxa. Thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 tan m\u00e1u v\u00e0 methemoglobin huy\u1ebft \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y.&nbsp;<\/p>\n\n\n\n<p>Nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 thi\u1ebfu h\u1ee5t G6PD cao h\u01a1n n\u00ean \u0111\u01b0\u1ee3c s\u00e0ng l\u1ecdc tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng Krystexxa.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span><strong>Tr\u1ecb gi\u00e1<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Dung d\u1ecbch ti\u00eam t\u0129nh m\u1ea1ch Krystexxa (8 mg\/mL) c\u00f3 gi\u00e1 kho\u1ea3ng $30.882 cho 1 ml. Chi ph\u00ed c\u00f3 th\u1ec3 thay \u0111\u1ed5i t\u00f9y thu\u1ed9c v\u00e0o nh\u00e0 thu\u1ed1c b\u1ea1n \u0111\u1ebfn. B\u1ec7nh nh\u00e2n c\u00f3 thu nh\u1eadp th\u1ea5p ho\u1eb7c kh\u00f4ng c\u00f3 b\u1ea3o hi\u1ec3m c\u00f3 th\u1ec3 tham gia c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh h\u1ed7 tr\u1ee3 b\u1ec7nh nh\u00e2n \u0111\u1ec3 gi\u1ea3m chi ph\u00ed \u0111i\u1ec1u tr\u1ecb. <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/financial-assistance\/\">Li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i<\/a> n\u1ebfu b\u1ea1n quan t\u00e2m \u0111\u1ebfn vi\u1ec7c nh\u1eadn h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh.<\/p>","protected":false},"excerpt":{"rendered":"<p>Krystexxa, c\u00f2n \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi t\u00ean g\u1ecdi chung l\u00e0 \u201cpegloticase\u201d, l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ti\u00eam \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00fat m\u00e3n t\u00ednh n\u1eb7ng, kh\u00e1ng tr\u1ecb \u1edf ng\u01b0\u1eddi l\u1edbn kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb g\u00fat th\u00f4ng th\u01b0\u1eddng. Krystexxa thu\u1ed9c nh\u00f3m thu\u1ed1c \u201cthu\u1ed1c h\u1ea1 acid uric m\u00e1u ho\u1eb7c thu\u1ed1c ch\u1ed1ng g\u00fat\u201d, c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1ef1 s\u1ea3n sinh qu\u00e1 m\u1ee9c acid uric \u1edf b\u1ec7nh nh\u00e2n g\u00fat.<\/p>","protected":false},"author":13,"featured_media":26373,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[4],"tags":[17],"class_list":["post-26368","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other-health-conditions","tag-dr-saba-rassouli"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Krystexxa: A Treatment for Chronic Gout - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn about Krystexxa and how it is used to treat gout. 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