{"id":26214,"date":"2024-06-25T12:07:43","date_gmt":"2024-06-25T19:07:43","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=26214"},"modified":"2025-07-16T16:56:28","modified_gmt":"2025-07-16T23:56:28","slug":"exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/","title":{"rendered":"Kh\u00e1m ph\u00e1 b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh: Tri\u1ec7u ch\u1ee9ng, ph\u00e2n nh\u00f3m v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb"},"content":{"rendered":"<p>Nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 t\u00ecnh tr\u1ea1ng m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 c\u00e1c kh\u00e1ng th\u1ec3 ph\u1ed5 bi\u1ebfn c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c nh\u01b0 th\u1ee5 th\u1ec3 acetylcholine (AChR) v\u00e0 th\u1ee5 th\u1ec3 tyrosine kinase \u0111\u1eb7c hi\u1ec7u c\u01a1 (MuSK) g\u00e2y ra b\u1ec7nh nh\u01b0\u1ee3c c\u01a1. MG huy\u1ebft thanh \u00e2m t\u00ednh l\u00e0 m\u1ed9t d\u1ea1ng b\u1ec7nh hi\u1ebfm g\u1eb7p v\u00e0 th\u01b0\u1eddng kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-2626a4df632b30dc6cb6ad1654b758da\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tN\u00f3i chuy\u1ec7n v\u1edbi chuy\u00ean gia v\u1ec1 h\u1ed7 tr\u1ee3 \u0111\u1ed3ng thanh to\u00e1n\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p>Nh\u00ecn chung, khi b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc MG, m\u1ed9t l\u01b0\u1ee3ng kh\u00e1ng th\u1ec3 AChR ho\u1eb7c kh\u00e1ng th\u1ec3 anti-MuSK c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c trong m\u00e1u. Tuy nhi\u00ean, trong tr\u01b0\u1eddng h\u1ee3p SnMG, b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 kh\u00e1ng th\u1ec3 AChR ho\u1eb7c kh\u00e1ng th\u1ec3 anti-MuSK trong m\u00e1u nh\u01b0ng v\u1eabn bi\u1ec3u hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng MG nh\u01b0 s\u1ee5p m\u00ed m\u1eaft, m\u1edd m\u1eaft, kh\u00f3 th\u1edf, kh\u00f3 nu\u1ed1t v\u00e0 kh\u00f3 n\u00f3i.&nbsp;<\/p>\n\n\n\n<p>Tr\u00ean th\u1ef1c t\u1ebf, \u0111\u1ea1i kh\u00e1i&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15885043\/#:~:text=Around%2010%2D20%25%20of%20myasthenia,muscle%20specific%20kinase%20(MuSK).\">10-20%<\/a>&nbsp;100% b\u1ec7nh nh\u00e2n MG \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n huy\u1ebft thanh \u00e2m t\u00ednh. Tuy nhi\u00ean, con s\u1ed1 th\u1ef1c t\u1ebf c\u00f3 th\u1ec3 cao h\u01a1n v\u00ec r\u1ea5t c\u00f3 th\u1ec3 nhi\u1ec1u b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ch\u00ednh x\u00e1c.<\/p>\n\n\n\n<p>B\u00e0i vi\u1ebft n\u00e0y th\u1ea3o lu\u1eadn v\u1ec1 c\u00e1c kh\u00eda c\u1ea1nh c\u01a1 b\u1ea3n c\u1ee7a MG huy\u1ebft thanh \u00e2m t\u00ednh, bao g\u1ed3m s\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa MG huy\u1ebft thanh \u00e2m t\u00ednh v\u00e0 MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh, c\u00e1c ph\u00e2n nh\u00f3m, tri\u1ec7u ch\u1ee9ng, ch\u1ea9n \u0111o\u00e1n v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc cho MG huy\u1ebft thanh \u00e2m t\u00ednh.&nbsp;<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#Difference_Between_Seronegative_and_Seropositive_Myasthenia_Gravis\" >S\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh v\u00e0 huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#Subtypes_of_Seronegative_MG\" >C\u00e1c ph\u00e2n nh\u00f3m c\u1ee7a MG huy\u1ebft thanh \u00e2m t\u00ednh<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#Double_Seronegative_MG\" >MG huy\u1ebft thanh \u00e2m t\u00ednh k\u00e9p<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#Triple_Seronegative_MG\" >MG huy\u1ebft thanh \u00e2m t\u00ednh ba l\u1ea7n<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#What_Are_the_Symptoms_of_Seronegative_Myasthenia_Gravis_SnMG\" >C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#How_Is_Seronegative_Myasthenia_Gravis_SnMG_Diagnosed\" >B\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/exploring-seronegative-myasthenia-gravis-symptoms-subtypes-and-treatments\/#What_Are_the_Treatment_Options_for_Seronegative_Myasthenia_Gravis_SnMG\" >C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 g\u00ec?<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Difference_Between_Seronegative_and_Seropositive_Myasthenia_Gravis\"><\/span>S\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh v\u00e0 huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Y\u1ebfu t\u1ed1 chung m\u00e0 c\u00e1c nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe xem x\u00e9t \u0111\u1ec3 ph\u00e2n bi\u1ec7t gi\u1eefa b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh v\u00e0 huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh l\u00e0 ki\u1ec3m tra s\u1ef1 c\u00f3 m\u1eb7t ho\u1eb7c v\u1eafng m\u1eb7t c\u1ee7a kh\u00e1ng th\u1ec3 th\u1ee5 th\u1ec3 acetylcholine (AChR) ho\u1eb7c kh\u00e1ng th\u1ec3 tyrosine kinase \u0111\u1eb7c hi\u1ec7u c\u01a1 (MuSK) trong m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n\n\n\n<p>Xung quanh&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15885043\/#:~:text=Around%2010%2D20%25%20of%20myasthenia,muscle%20specific%20kinase%20(MuSK).\">80-90%<\/a>&nbsp;trong s\u1ed1 nh\u1eefng ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc MG c\u00f3 kh\u00e1ng th\u1ec3 AChR trong m\u00e1u. Th\u1ee5 th\u1ec3 acetylcholine (AChR) l\u00e0 kh\u00e1ng th\u1ec3 \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf b\u1ec7nh nh\u00e2n MG.&nbsp;<\/p>\n\n\n\n<p>Tr\u01b0\u1edbc \u0111\u00e2y, khi b\u1ec7nh nh\u00e2n MG kh\u00f4ng ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c kh\u00e1ng th\u1ec3 AChR, h\u1ecd \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/0022510X9190067H\">MG huy\u1ebft thanh \u00e2m t\u00ednh<\/a>Tuy nhi\u00ean, sau nhi\u1ec1u nghi\u00ean c\u1ee9u h\u01a1n, ng\u01b0\u1eddi ta ph\u00e1t hi\u1ec7n ra r\u1eb1ng protein li\u00ean quan \u0111\u1ebfn th\u1ee5 th\u1ec3 lipoprotein m\u1eadt \u0111\u1ed9 th\u1ea5p 4 (LRP4) c\u00f3 li\u00ean quan \u0111\u1ebfn kh\u1edbp th\u1ea7n kinh c\u01a1.&nbsp;&nbsp;<\/p>\n\n\n\n<p>T\u00f3m l\u1ea1i, b\u1ec7nh nh\u00e2n&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7734299\/\">kh\u00f4ng c\u00f3 kh\u00e1ng th\u1ec3 t\u1ef1 mi\u1ec5n AChR ho\u1eb7c kh\u00e1ng th\u1ec3 kh\u00e1ng MuSK trong m\u00e1u<\/a>&nbsp;\u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n l\u00e0 MG huy\u1ebft thanh \u00e2m t\u00ednh, trong khi nh\u1eefng ng\u01b0\u1eddi c\u00f3 kh\u00e1ng th\u1ec3 t\u1ef1 mi\u1ec5n AChR ho\u1eb7c kh\u00e1ng th\u1ec3 kh\u00e1ng MuSK \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n l\u00e0 MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Subtypes_of_Seronegative_MG\"><\/span>C\u00e1c ph\u00e2n nh\u00f3m c\u1ee7a MG huy\u1ebft thanh \u00e2m t\u00ednh<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Nhi\u1ec1u t\u00e0i li\u1ec7u kh\u00e1c nhau \u0111\u00e3 ph\u00e2n lo\u1ea1i th\u00eam b\u1ec7nh MG huy\u1ebft thanh \u00e2m t\u00ednh&nbsp;<a href=\"https:\/\/mghope.org\/different-types-of-mg\">th\u00e0nh hai ph\u00e2n nh\u00f3m d\u1ef1a tr\u00ean s\u1ef1 c\u00f3 m\u1eb7t ho\u1eb7c v\u1eafng m\u1eb7t c\u1ee7a kh\u00e1ng th\u1ec3<\/a>:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Double_Seronegative_MG\"><\/span>MG huy\u1ebft thanh \u00e2m t\u00ednh k\u00e9p<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u1ede b\u1ec7nh MG huy\u1ebft thanh \u00e2m t\u00ednh k\u00e9p, c\u1ea3 kh\u00e1ng th\u1ec3 AChR v\u00e0 MuSK \u0111\u1ec1u kh\u00f4ng c\u00f3 trong m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Triple_Seronegative_MG\"><\/span>MG huy\u1ebft thanh \u00e2m t\u00ednh ba l\u1ea7n<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u1ede b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh ba l\u1ea7n, kh\u00f4ng c\u00f3 kh\u00e1ng th\u1ec3 AChR, MuSK v\u00e0 LRP4 trong m\u00e1u.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_the_Symptoms_of_Seronegative_Myasthenia_Gravis_SnMG\"><\/span>C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"223\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids.jpg\" alt=\"Seronegative myasthenia gravis patient with droopy eyelids\" class=\"wp-image-26427\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids-300x159.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids-86x46.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids-167x89.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids-280x149.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/08\/droopy-eyelids-370x196.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a SnMG gi\u1ed1ng v\u1edbi MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh. Gi\u1ed1ng nh\u01b0 MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh, MG huy\u1ebft thanh \u00e2m t\u00ednh c\u00f3 th\u1ec3 bi\u1ec3u hi\u1ec7n \u1edf m\u1eaft ho\u1eb7c to\u00e0n th\u00e2n. Tuy nhi\u00ean,&nbsp;<a href=\"https:\/\/www.jkna.org\/journal\/view.php?number=3939\">t\u1ef7 l\u1ec7 m\u1eafc MG \u1edf m\u1eaft cao h\u01a1n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh<\/a>&nbsp;h\u01a1n \u1edf b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh, v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 t\u1eeb nh\u1eb9 \u0111\u1ebfn n\u1eb7ng. C\u00e1c tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn bao g\u1ed3m:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>M\u00ed m\u1eaft s\u1ee5p xu\u1ed1ng<\/li>\n\n\n\n<li>Nh\u00ecn m\u1edd ho\u1eb7c nh\u00ecn \u0111\u00f4i<\/li>\n\n\n\n<li>Kh\u00f3 nhai, nu\u1ed1t v\u00e0 n\u00f3i<\/li>\n\n\n\n<li>Y\u1ebfu c\u01a1 m\u1eb7t<\/li>\n\n\n\n<li>Kh\u00f3 th\u1edf (trong tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng)<\/li>\n<\/ul>\n\n\n\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng tr\u1edf n\u00ean t\u1ed3i t\u1ec7 h\u01a1n khi ho\u1ea1t \u0111\u1ed9ng l\u1eb7p \u0111i l\u1eb7p l\u1ea1i v\u00e0 c\u1ea3i thi\u1ec7n khi ngh\u1ec9 ng\u01a1i.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-fe5650a0ed273696ad7b68504272f13e\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tIVIG c\u00f3 th\u1ec3 gi\u00fap \u00edch g\u00ec? | Th\u00f4ng tin \u0111i\u1ec1u tr\u1ecb IVIG mi\u1ec5n ph\u00ed | Kh\u00f3 kh\u0103n trong ch\u1ea9n \u0111o\u00e1n?\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">L\u00ean l\u1ecbch t\u01b0 v\u1ea5n<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Seronegative_Myasthenia_Gravis_SnMG_Diagnosed\"><\/span>B\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Ch\u1ea9n \u0111o\u00e1n b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh \u0111\u00f2i h\u1ecfi k\u1ef9 n\u0103ng ch\u1ea9n \u0111o\u00e1n n\u00e2ng cao so v\u1edbi b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh.<\/p>\n\n\n\n<p>Th\u00f4ng th\u01b0\u1eddng, b\u00e1c s\u0129 chuy\u00ean khoa nh\u01b0\u1ee3c c\u01a1 s\u1ebd ti\u1ebfn h\u00e0nh \u0111\u00e1nh gi\u00e1 k\u1ef9 l\u01b0\u1ee1ng ti\u1ec1n s\u1eed b\u1ec7nh l\u00fd v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n, \u0111\u1ed3ng th\u1eddi th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc bao g\u1ed3m:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>X\u00e9t nghi\u1ec7m m\u00e1u \u0111\u1ec3 ki\u1ec3m tra s\u1ef1 c\u00f3 m\u1eb7t ho\u1eb7c v\u1eafng m\u1eb7t c\u1ee7a c\u00e1c kh\u00e1ng th\u1ec3 t\u1ef1 mi\u1ec5n AChr, MuSK v\u00e0 LRP4<\/li>\n\n\n\n<li>\u0110i\u1ec7n c\u01a1 \u0111\u1ed3 (EMG)<\/li>\n\n\n\n<li>K\u00edch th\u00edch th\u1ea7n kinh l\u1eb7p \u0111i l\u1eb7p l\u1ea1i (RNS)<\/li>\n\n\n\n<li>\u0110i\u1ec7n c\u01a1 \u0111\u1ed3 s\u1ee3i \u0111\u01a1n (SFEMG)<\/li>\n<\/ul>\n\n\n\n<p>G\u1ea7n \u0111\u00e2y, m\u1ed9t k\u1ef9 thu\u1eadt m\u1edbi g\u1ecdi l\u00e0 x\u00e9t nghi\u1ec7m d\u1ef1a tr\u00ean t\u1ebf b\u00e0o (CBA) \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u00e0 c\u00f3 l\u1ee3i cho vi\u1ec7c ch\u1ea9n \u0111o\u00e1n b\u1ec7nh nh\u00e2n huy\u1ebft thanh \u00e2m t\u00ednh. A&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35366559\/\">h\u1ecdc<\/a>&nbsp;M\u1ed9t nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean T\u1ea1p ch\u00ed Mi\u1ec5n d\u1ecbch h\u1ecdc Th\u1ea7n kinh cho th\u1ea5y khi x\u00e9t nghi\u1ec7m 99 b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh b\u1eb1ng x\u00e9t nghi\u1ec7m t\u1ebf b\u00e0o (CBA), 18 b\u1ec7nh nh\u00e2n c\u00f3 k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh v\u1edbi AChR. Nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y \u1ee7ng h\u1ed9 vi\u1ec7c s\u1eed d\u1ee5ng x\u00e9t nghi\u1ec7m AChR CBA theo c\u1ee5m \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n MG huy\u1ebft thanh \u00e2m t\u00ednh.&nbsp;<\/p>\n\n\n\n<p>T\u01b0\u01a1ng t\u1ef1 nh\u01b0 v\u1eady, m\u1ed9t c\u00e1i kh\u00e1c&nbsp;<a href=\"https:\/\/jnnp.bmj.com\/content\/93\/9\/995.abstract\">h\u1ecdc<\/a>&nbsp;\u0111\u00e3 b\u00e1o c\u00e1o nh\u1eefng k\u1ebft qu\u1ea3 t\u01b0\u01a1ng t\u1ef1 v\u00e0 nh\u1ea5n m\u1ea1nh t\u00ednh h\u1eefu \u00edch trong ch\u1ea9n \u0111o\u00e1n c\u1ee7a vi\u1ec7c th\u1ef1c hi\u1ec7n CBA \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n MG huy\u1ebft thanh \u00e2m t\u00ednh.&nbsp;<\/p>\n\n\n\n<p>H\u1ea7u h\u1ebft, nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m \u00e2m t\u00ednh v\u1edbi MG th\u01b0\u1eddng b\u1ecb c\u00e1c chuy\u00ean gia y t\u1ebf b\u1ecf qua, khi\u1ebfn h\u1ecd c\u00f3 nguy c\u01a1 nh\u1eadn \u0111\u01b0\u1ee3c d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c k\u00e9m ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 ch\u1eadm tr\u1ec5.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Are_the_Treatment_Options_for_Seronegative_Myasthenia_Gravis_SnMG\"><\/span>C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>B\u1ec7nh nh\u00e2n m\u1eafc MG huy\u1ebft thanh \u00e2m t\u00ednh th\u01b0\u1eddng g\u1eb7p kh\u00f3 kh\u0103n trong vi\u1ec7c ti\u1ebfp nh\u1eadn \u0111i\u1ec1u tr\u1ecb. Ngay c\u1ea3 khi \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb, h\u1ecd c\u00f3 th\u1ec3 kh\u00f4ng \u0111\u01b0\u1ee3c ch\u0103m s\u00f3c \u0111\u1ea7y \u0111\u1ee7 \u0111\u1ec3 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng. V\u00ec SnMG kh\u00f3 ch\u1ea9n \u0111o\u00e1n, vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 m\u1ea5t nhi\u1ec1u th\u1eddi gian h\u01a1n so v\u1edbi c\u00e1c b\u1ec7nh l\u00fd kh\u00e1c.&nbsp;<\/p>\n\n\n\n<p>Hi\u1ec7n nay, h\u1ea7u h\u1ebft c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ec9 d\u00e0nh cho b\u1ec7nh nh\u00e2n nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh d\u01b0\u01a1ng t\u00ednh. Tuy nhi\u00ean, b\u1ec7nh nh\u00e2n nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh c\u00f3 th\u1ec3 th\u1eed c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb sau d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Thu\u1ed1c (v\u00ed d\u1ee5, Mestinon)<\/li>\n\n\n\n<li>Corticosteroid (v\u00ed d\u1ee5, prednisone, v.v.)<\/li>\n\n\n\n<li><a href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig\/\/ivig\/\">Globulin mi\u1ec5n d\u1ecbch ti\u00eam t\u0129nh m\u1ea1ch (IVIG)<\/a>&nbsp;ho\u1eb7c&nbsp;<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/what-is-scig\/\">immunoglobulin d\u01b0\u1edbi da (SCIG)<\/a>)<\/li>\n\n\n\n<li>Huy\u1ebft t\u01b0\u01a1ng t\u00e1ch (PLEX)<\/li>\n\n\n\n<li>Li\u1ec7u ph\u00e1p \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch<\/li>\n\n\n\n<li><a href=\"https:\/\/ameripharmaspecialty.com\/vi\/myasthenia-gravis\/thymectomy-for-myasthenia-gravis-what-patients-need-to-know\/\">C\u1eaft b\u1ecf tuy\u1ebfn \u1ee9c<\/a><\/li>\n<\/ul>\n\n\n\n<p>Nghi\u00ean c\u1ee9u \u0111ang \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh v\u1ec1 b\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG). C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u v\u1eabn \u0111ang c\u1ed1 g\u1eafng t\u00ecm hi\u1ec3u lo\u1ea1i kh\u00e1ng th\u1ec3 ho\u1eb7c protein n\u00e0o li\u00ean quan \u0111\u1ebfn d\u1ea1ng MG n\u00e0y \u0111\u1ec3 c\u00f3 th\u1ec3 \u0111\u01b0a ra ch\u1ea9n \u0111o\u00e1n v\u00e0 k\u1ebf ho\u1ea1ch \u0111i\u1ec1u tr\u1ecb ch\u00ednh x\u00e1c cho b\u1ec7nh nh\u00e2n.&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>B\u1ec7nh nh\u01b0\u1ee3c c\u01a1 huy\u1ebft thanh \u00e2m t\u00ednh (SnMG) l\u00e0 t\u00ecnh tr\u1ea1ng m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 kh\u00e1ng th\u1ec3 ph\u1ed5 bi\u1ebfn c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c nh\u01b0 th\u1ee5 th\u1ec3 acetylcholine (AChR) v\u00e0 th\u1ee5 th\u1ec3 tyrosine kinase \u0111\u1eb7c hi\u1ec7u c\u01a1 (MuSK) g\u00e2y ra b\u1ec7nh nh\u01b0\u1ee3c c\u01a1.<\/p>","protected":false},"author":7,"featured_media":26215,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[10],"tags":[8],"class_list":["post-26214","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-myasthenia-gravis","tag-dr-christine-leduc"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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gi\u1ea3","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/christine-leduc\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-300x200.jpg",300,200,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-768x512.jpg",768,512,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/consultation.jpg",1280,853,false]},"uagb_author_info":{"display_name":"Dr. 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