{"id":26015,"date":"2024-04-19T13:33:16","date_gmt":"2024-04-19T20:33:16","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/why-hemophilia-is-more-common-in-males\/"},"modified":"2024-08-13T16:44:14","modified_gmt":"2024-08-13T23:44:14","slug":"why-hemophilia-is-more-common-in-males","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/hemophilia\/why-hemophilia-is-more-common-in-males\/","title":{"rendered":"T\u1ea1i sao b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng th\u01b0\u1eddng g\u1eb7p \u1edf nam gi\u1edbi h\u01a1n?"},"content":{"rendered":"\n<p><span style=\"font-weight: 400;\">Hemophilia is more common in males due to the fact that they have only one copy of the gene on the X chromosome. If any changes occur in that gene, females can compensate for the defect with an additional copy of the gene, but males cannot.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-4f57845f043250f0edb1fda021e84d6c\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist About Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">It is also the reason why more males get other X-linked disorders like color blindness. X-linked disorders occur due to changes in the gene on the X chromosome.&nbsp;<\/span>&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">A Quick Overview of Hemophilia, Causes, Types, and Occurrence<\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Hemophilia is a genetic disorder in which the blood does not clot as it should. As a result, it can lead to excessive bruising and nosebleeds. Severe hemophilia can cause spontaneous bleeding (bleeding with no obvious cause).&nbsp;<\/span><br><span style=\"font-weight: 400;\">Hemophilia occurs due to changes in the genes that instruct the body to make blood-clotting proteins called clotting factors. The common types are:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Hemophilia A<\/b><span style=\"font-weight: 400;\">: Also known as <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/hemophilia\/classic-hemophilia-types-symptoms-treatment\/\"><span style=\"font-weight: 400;\">classic hemophilia<\/span><\/a><span style=\"font-weight: 400;\">, it occurs due to having little or no clotting factor VIII.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Hemophilia B<\/b><span style=\"font-weight: 400;\">: Also known as Christmas disease, it occurs due to having little or no clotting factor IX.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p>The more common type\u2014Hemophilia A\u2014affects 1 in 5,000 male live births. According to reports from the <a href=\"https:\/\/www.cdc.gov\/\">Centers for Disease Control and Prevention<\/a> (CDC), nearly 400 babies are born with this disorder each year in the U.S. Though the exact numbers remain unknown, recent data suggest about 33,000 American males have this condition [<a href=\"https:\/\/www.cdc.gov\/hemophilia\/data-research\/?CDC_AAref_Val=https:\/\/www.cdc.gov\/ncbddd\/hemophilia\/data.html\">1<\/a>].<br>\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why Hemophilia Is More Common in Males: Understanding the Genetics and Inheritance<\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">The fundamental reason why hemophilia is more common in males is that they have only one X chromosome.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">The X chromosome contains the genes for clotting factors VIII and IX. Changes in these genes lead to little or no clotting factor production. Consequently, the blood does not clot properly.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">The X chromosome contains the genes for clotting factors VIII and IX. Changes in these genes lead to little or no clotting factor production. Consequently, the blood does not clot properly.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Because males have only one chromosome, one altered copy of the gene is enough to cause symptoms. On the other hand, females have two copies of these genes, and changes in one copy typically do not cause the condition.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Moreover, males get an earlier diagnosis than females. Early diagnosis in males is a result of the myth that females cannot get hemophilia. Many females may even ignore the signs of mild hemophilia, such as heavy bleeding.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">According to a 2020 study, females with moderate symptoms receive a diagnosis about 6 months later than males. In severe cases, females face delays of approximately 40 months [<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7845070\/#rth212468-bib-0012\"><span style=\"font-weight: 400;\">2<\/span><\/a><span style=\"font-weight: 400;\">].<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Hemophilia is more common in males born to a female carrying the affected gene and an unaffected male. In such cases, there is a 1 in 4 chance of having a baby boy with the condition. On the other hand, males born to a hemophilic father and unaffected mother are less likely to get the condition.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">The risk of hemophilia is the same for males and females if both parents have the faulty gene. In such cases, there is a 1 in 4 chance that a baby girl will be a carrier.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-856a69cc38bbba0be6a13e9719761bf7\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Why Is Hemophilia Rare in Females?<\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">For females to get hemophilia, both X chromosomes have to be altered. Sometimes, hemophilia may result from having one affected X chromosome and another non-functioning chromosome.&nbsp;&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">A female with one altered gene is a \u201ccarrier.\u201d She can pass the affected gene on to her children. Female carriers do not usually experience <a href=\"https:\/\/ameripharmaspecialty.com\/conditions-treatments\/hemophilia\/\">symptoms of hemophilia<\/a>, but some do.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">The prevailing misbelief that hemophilia is a \u201cmale-only\u201d disease could be one of the reasons for fewer diagnoses in females.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Key Takeaways<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Hemophilia is more common in males because they have only one X chromosome.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Though some providers consider it a \u201cmale-only\u201d disease, hemophilia can affect females as well.&nbsp;&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Many health experts think underrecognition and underdiagnosis in females could obscure the real-world scenario. Females appear to get delayed diagnoses.&nbsp;<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>B\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng ph\u1ed5 bi\u1ebfn h\u01a1n \u1edf nam gi\u1edbi do h\u1ecd ch\u1ec9 c\u00f3 m\u1ed9t b\u1ea3n sao c\u1ee7a gen tr\u00ean nhi\u1ec5m s\u1eafc th\u1ec3 X. N\u1ebfu c\u00f3 b\u1ea5t k\u1ef3 thay \u0111\u1ed5i n\u00e0o x\u1ea3y ra \u1edf gen \u0111\u00f3, ph\u1ee5 n\u1eef c\u00f3 th\u1ec3 b\u00f9 \u0111\u1eafp khi\u1ebfm khuy\u1ebft b\u1eb1ng m\u1ed9t b\u1ea3n sao b\u1ed5 sung c\u1ee7a gen, nh\u01b0ng nam gi\u1edbi th\u00ec kh\u00f4ng.\u00a0<\/p>","protected":false},"author":13,"featured_media":25930,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[6],"tags":[17],"class_list":["post-26015","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hemophilia","tag-dr-saba-rassouli"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Why Is Hemophilia More Common in Males? - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"This article explains the reasons why hemophilia is more common in males. 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She received her pharmacy degree from Marshall B. Ketchum University in 2022, where she graduated cum laude. The most rewarding part of her job is having the opportunity to care for each patient as if they were family and hearing about how happy and satisfied they are with the services provided by AmeriPharma. In her free time, she likes to go on walks, read books, and try different restaurants and foods.\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/vi\\\/author\\\/saba-rassouli\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"T\u1ea1i sao b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng ph\u1ed5 bi\u1ebfn h\u01a1n \u1edf nam gi\u1edbi? - Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t AmeriPharma\u00ae","description":"B\u00e0i vi\u1ebft n\u00e0y gi\u1ea3i th\u00edch l\u00fd do t\u1ea1i sao b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng ph\u1ed5 bi\u1ebfn h\u01a1n \u1edf nam gi\u1edbi. 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