{"id":25995,"date":"2024-06-05T08:00:14","date_gmt":"2024-06-05T15:00:14","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/"},"modified":"2024-07-09T16:30:28","modified_gmt":"2024-07-09T23:30:28","slug":"common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/","title":{"rendered":"Suy gi\u1ea3m mi\u1ec5n d\u1ecbch bi\u1ebfn \u0111\u1ed5i ph\u1ed5 bi\u1ebfn: Gi\u1ea3i m\u00e3 r\u1ed1i lo\u1ea1n mi\u1ec5n d\u1ecbch k\u00e9o d\u00e0i h\u00e0ng th\u1eadp k\u1ef7"},"content":{"rendered":"<p>Five decades have passed since the term \u201ccommon variable immunodeficiency\u201d was first used in medicine. Still, many questions remain unanswered, and some answers are ambiguous. In this article, we will look at the latest evidence to answer some of the common questions about this condition. <\/p>\n\n\n<div  id=\"call-to-action-ecd389385d8d183c2d1c3269ed08bd4d\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p>&nbsp;<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Is_Common_Variable_Immunodeficiency\" >What Is Common Variable Immunodeficiency?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Causes_Common_Variable_Immunodeficiency\" >What Causes Common Variable Immunodeficiency?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Are_the_Risk_Factors\" >What Are the Risk Factors?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Are_the_Symptoms_of_Common_Variable_Immunodeficiency\" >What Are the Symptoms of Common Variable Immunodeficiency?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#How_Is_Common_Variable_Immunodeficiency_Diagnosed\" >How Is Common Variable Immunodeficiency Diagnosed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#How_Is_CVID_Treated\" >How Is CVID Treated?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#Treatment_Can_Be_Challenging_in_People_With_COVID\" >Treatment Can Be Challenging in People With COVID<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Are_the_Complications_of_CVID\" >What Are the Complications of CVID?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#Can_Women_With_CVID_Get_Pregnant\" >Can Women With CVID Get Pregnant?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Is_the_Life_Expectancy_of_a_Person_With_CVID\" >What Is the Life Expectancy of a Person With CVID?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Is_the_Difference_Between_CVID_and_IgG_Deficiency\" >What Is the Difference Between CVID and IgG Deficiency?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/common-variable-immunodeficiency-demystifying-the-decades-old-immune-disorder\/#What_Infections_Are_Common_in_CVID\" >What Infections Are Common in CVID?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Common_Variable_Immunodeficiency\"><\/span>What Is Common Variable Immunodeficiency?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Common variable immunodeficiency (CVID) is an umbrella term for immune disorders that cause low levels of infection-fighting proteins called <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/immunoglobulins-ig\/\"><span style=\"font-weight: 400;\">immunoglobulins<\/span><\/a><span style=\"font-weight: 400;\">. As a result, people with CVID are more likely to experience frequent infections of the ears, sinuses, lungs, and digestive tract.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other names for this condition are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Common variable hypogammaglobulinemia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypogammaglobulinemia, acquired<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Immunoglobulin deficiency, late-onset<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Idiopathic immunoglobulin deficiency<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Primary antibody deficiency<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Primary hypogammaglobulinemia<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">There are over 400 conditions that cause immunoglobulin deficiency. They are known as primary immunodeficiencies. Of them, CVID is relatively common, hence the name.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, CVID overall is rare, affecting fewer than 5,000 Americans. CVID is a long-term (chronic) condition that often requires lifelong treatment.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Causes_Common_Variable_Immunodeficiency\"><\/span>What Causes Common Variable Immunodeficiency?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In about 90% of cases, researchers are not certain what exactly causes CVID. They believe both environmental and genetic factors may be responsible.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Genetic changes (mutations) that cause CVID may be passed down from parents to children. In other cases, they may occur randomly or after exposure to triggers. Potential triggers include UV radiation and viral infections.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mutations in the genes that regulate B cell function are likely the culprit. <\/span><a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/b-cell\"><span style=\"font-weight: 400;\">B cells<\/span><\/a><span style=\"font-weight: 400;\"> are specialized white blood cells; they produce immunoglobulins or antibodies. People with CVID have enough B cells, but these cells do not make enough antibodies.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Are_the_Risk_Factors\"><\/span>What Are the Risk Factors?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">CVID can affect anyone, irrespective of age or sex. Nonetheless, it often affects adults, and most people are diagnosed between ages 20 and 50.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Are_the_Symptoms_of_Common_Variable_Immunodeficiency\"><\/span>What Are the Symptoms of Common Variable Immunodeficiency?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-24157 size-full alignright\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/woman-cough.jpg\" alt=\"Female Patient With Symptoms of CVID\" width=\"420\" height=\"280\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Symptoms may be mild or severe and can vary from person to person. They can include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nagging cough (sometimes, coughing up blood)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ear infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sinus infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Repeated lung infections, possibly leading to bronchitis or pneumonia\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual response to vaccines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal liver<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low platelet count<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen joints<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Enlarged spleen<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen lymph nodes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Red or purple spots on the skin<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_Common_Variable_Immunodeficiency_Diagnosed\"><\/span>How Is Common Variable Immunodeficiency Diagnosed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Your provider might suspect CVID if you have characteristic symptoms and risk factors, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Frequent ear, sinus, or lung infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual response to vaccines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A family history of the condition<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">To confirm the diagnosis, your doctor will order blood tests. These tests will help your provider determine antibody levels and how well your body responds to a vaccine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If your provider is sure you have CVID, they will recommend yearly tests to detect complications. Complications include autoimmune disorders, cancers, and lung problems. Tests may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood tests<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Imaging tests<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n\n\n<div  id=\"call-to-action-196c005c3dcb20a96e4dd209b087836f\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Financial Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_CVID_Treated\"><\/span>How Is CVID Treated?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">No cure for CVID exists; however, there are several treatments to keep your condition in check.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">Once the diagnosis is confirmed, your provider will likely give you immunoglobulin (IgG) replacement therapy. It contains antibodies obtained from healthy donors.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">There are two ways you can receive donor-derived antibodies:\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/\"><b>Intravenous immunoglobulin (IVIG)<\/b><\/a><span style=\"font-weight: 400;\">: IVIG is administered into a vein through a needle. The usual dose is 400 &#8211; 600 mg\/kg every 2 to 4 weeks.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/what-is-scig\/\"><b>Subcutaneous immunoglobulin (SCIG)<\/b><\/a><span style=\"font-weight: 400;\">: SCIG is given as a shot under your skin. The usual dose is 160 mg\/kg once a week.\u00a0<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">Most people respond well to IgG replacement therapy. It is highly effective in reducing the recurrence of infections and joint problems. Likewise, IgG therapy reduces the severity of complications, such as autoimmune disorders. People often need treatment for their lifetime.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">During the therapy, your healthcare provider will monitor you for side effects. Common side effects include backache, nausea, vomiting, chills, fever, muscle pain, and fatigue. To reduce the odds of such reactions, <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig-premedication-essential-things-to-know\/\"><span style=\"font-weight: 400;\">premedication<\/span><\/a><span style=\"font-weight: 400;\"> may be necessary.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">Your provider may prescribe antibiotics to treat infections. In some cases, antibiotics may be used regularly to prevent infections.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">Other treatments are specific to the system involved. For example, vitamin B12 injections may help someone with digestive problems leading to B12 deficiency. Likewise, those with breathing difficulty may benefit from inhaled corticosteroids and similar medications.\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">If you have a low platelet count, it is best to avoid aspirin. Moreover, people with CVID should not receive live virus vaccines. Examples include the chickenpox vaccine and the MMR vaccine.<\/span><br \/>\n&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Treatment_Can_Be_Challenging_in_People_With_COVID\"><\/span>Treatment Can Be Challenging in People With COVID<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">COVID-19 may be more severe in people with immunodeficiencies like CVID, though a clear association is lacking. Most people with CVID at risk of COVID-19 are treated with convalescent plasma or IVIG.\u00a0<\/span><br \/>\n&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Are_the_Complications_of_CVID\"><\/span>What Are the Complications of CVID?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">CVID can make you more likely to get:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Autoimmune disorders<\/b><span style=\"font-weight: 400;\">. These disorders cause your immune system to destroy the body\u2019s healthy tissues. People with CVID are at higher risk of developing <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/idiopathic-thrombocytopenic-purpura-itp\/\"><span style=\"font-weight: 400;\">immune thrombocytopenia<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/autoimmune-hemolytic-anemia-causes-diagnosis-and-treatment-options\/\"><span style=\"font-weight: 400;\">autoimmune hemolytic anemia<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/21144-bronchiectasis\"><b>Bronchiectasis<\/b><\/a><span style=\"font-weight: 400;\">. This occurs when there is irreversible damage to the lungs due to repeated infections.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cancers<\/b><span style=\"font-weight: 400;\">. Blood cancer and stomach cancer occur more frequently in people with CVID.\u00a0<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Can_Women_With_CVID_Get_Pregnant\"><\/span>Can Women With CVID Get Pregnant?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Thanks to IVIG, women with CVID can get pregnant without any additional risks. However, they should receive periodic IVIG therapy with customized doses to reach the desired IgG levels in the newborn [<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19642519\/#\"><span style=\"font-weight: 400;\">1<\/span><\/a><span style=\"font-weight: 400;\">].<\/span><br \/>\n&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_the_Life_Expectancy_of_a_Person_With_CVID\"><\/span>What Is the Life Expectancy of a Person With CVID?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">With timely diagnosis and appropriate treatment, most people live well into adulthood. The key factors that affect life expectancy are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severity of autoimmune disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Recurrent infections, particularly those affecting the lungs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Development of cancers<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">IVIG and antibiotic therapy have dramatically reduced deaths due to bacterial infections. Most deaths occur due to noninfectious complications, such as cancers.\u00a0<\/span><br \/>\n&nbsp;<\/p>\n\n\n<div  id=\"call-to-action-ecd389385d8d183c2d1c3269ed08bd4d\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_the_Difference_Between_CVID_and_IgG_Deficiency\"><\/span>What Is the Difference Between CVID and IgG Deficiency?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">CVID causes low levels of almost all immunoglobulin classes, whereas <\/span><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/immunoglobulin-igg-deficiency\/\"><span style=\"font-weight: 400;\">IgG deficiency<\/span><\/a><span style=\"font-weight: 400;\"> is when you have low levels of immunoglobulin G (IgG). The five major immunoglobulin classes are IgA, IgG, IgM, IgD, and IgE.\u00a0<\/span><br \/>\n&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Infections_Are_Common_in_CVID\"><\/span>What Infections Are Common in CVID?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most frequent infections in CVID are those involving the ears, sinuses, and respiratory tract.\u00a0<\/span><br \/>\n&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Five decades have passed since the term \u201ccommon variable immunodeficiency\u201d was first used in medicine. Still, many questions remain unanswered, and some answers are ambiguous. In this article, we will look at the latest evidence to answer some of the common questions about this condition.\u00a0<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>\u0110\u00e3 n\u0103m th\u1eadp k\u1ef7 tr\u00f4i qua k\u1ec3 t\u1eeb khi thu\u1eadt ng\u1eef &quot;suy gi\u1ea3m mi\u1ec5n d\u1ecbch bi\u1ebfn thi\u00ean th\u00f4ng th\u01b0\u1eddng&quot; l\u1ea7n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong y h\u1ecdc. Tuy nhi\u00ean, v\u1eabn c\u00f2n nhi\u1ec1u c\u00e2u h\u1ecfi ch\u01b0a \u0111\u01b0\u1ee3c gi\u1ea3i \u0111\u00e1p, v\u00e0 m\u1ed9t s\u1ed1 c\u00e2u tr\u1ea3 l\u1eddi c\u00f2n m\u01a1 h\u1ed3. Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd xem x\u00e9t nh\u1eefng b\u1eb1ng ch\u1ee9ng m\u1edbi nh\u1ea5t \u0111\u1ec3 gi\u1ea3i \u0111\u00e1p m\u1ed9t s\u1ed1 c\u00e2u h\u1ecfi th\u01b0\u1eddng g\u1eb7p v\u1ec1 t\u00ecnh tr\u1ea1ng n\u00e0y.\u00a0<\/p>","protected":false},"author":13,"featured_media":25962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[4],"tags":[17],"class_list":["post-25995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other-health-conditions","tag-dr-saba-rassouli"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Common Variable Immunodeficiency: Demystifying the Decades-Old Immune Disorder<\/title>\n<meta name=\"description\" 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Care"},"image":{"@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ameripharma\/"]},{"@type":"Person","@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/person\/f70b3467e035aab4ae14bdadd64c5c01","name":"Ti\u1ebfn s\u0129 Saba Rassouli, Ti\u1ebfn s\u0129 D\u01b0\u1ee3c","image":{"@type":"ImageObject","inLanguage":"vi","@id":"https:\/\/secure.gravatar.com\/avatar\/a5087340dca0d3046e3ff88f5dfa11d515d21ea9e06e6aec23e56d7fddfee7ce?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a5087340dca0d3046e3ff88f5dfa11d515d21ea9e06e6aec23e56d7fddfee7ce?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a5087340dca0d3046e3ff88f5dfa11d515d21ea9e06e6aec23e56d7fddfee7ce?s=96&d=mm&r=g","caption":"Dr. Saba Rassouli, PharmD"},"description":"Ti\u1ebfn s\u0129 Saba Rassouli, Ti\u1ebfn s\u0129 D\u01b0\u1ee3c sinh ra v\u00e0 l\u1edbn l\u00ean t\u1ea1i Iran. C\u00f4 \u0111\u00e3 nh\u1eadn b\u1eb1ng d\u01b0\u1ee3c s\u0129 c\u1ee7a \u0110\u1ea1i h\u1ecdc Marshall B. Ketchum v\u00e0o n\u0103m 2022, n\u01a1i c\u00f4 t\u1ed1t nghi\u1ec7p lo\u1ea1i xu\u1ea5t s\u1eafc. Ph\u1ea7n b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a c\u00f4 l\u00e0 c\u00f3 c\u01a1 h\u1ed9i ch\u0103m s\u00f3c t\u1eebng b\u1ec7nh nh\u00e2n nh\u01b0 th\u1ec3 h\u1ecd l\u00e0 gia \u0111\u00ecnh v\u00e0 l\u1eafng nghe h\u1ecd n\u00f3i v\u1ec1 m\u1ee9c \u0111\u1ed9 h\u1ea1nh ph\u00fac v\u00e0 h\u00e0i l\u00f2ng c\u1ee7a h\u1ecd v\u1edbi c\u00e1c d\u1ecbch v\u1ee5 do AmeriPharma cung c\u1ea5p. 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In this article, we will look at the latest evidence to answer some of the common questions about this condition.\u00a0","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-300x200.jpg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/06\/immunoglobulins.jpg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Saba Rassouli, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/saba-rassouli\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/other-health-conditions\/\" rel=\"category tag\">Other Health Conditions<\/a>","rttpg_excerpt":"Five decades have passed since the term \u201ccommon variable immunodeficiency\u201d was first used in medicine. Still, many questions remain unanswered, and some answers are ambiguous. In this article, we will look at the latest evidence to answer some of the common questions about this condition.\u00a0","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/25995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/comments?post=25995"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/25995\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media\/25962"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media?parent=25995"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/categories?post=25995"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/tags?post=25995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}