{"id":24691,"date":"2023-11-23T08:05:00","date_gmt":"2023-11-23T08:05:00","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=24691"},"modified":"2024-07-09T12:12:52","modified_gmt":"2024-07-09T19:12:52","slug":"ivig-for-infertility-is-this-treatment-right-for-you","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/","title":{"rendered":"IVIG \u0111i\u1ec1u tr\u1ecb v\u00f4 sinh: Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y c\u00f3 ph\u00f9 h\u1ee3p v\u1edbi b\u1ea1n kh\u00f4ng?"},"content":{"rendered":"\n<p>The use of&nbsp;<a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/\">IVIG<\/a>&nbsp;for infertility and in vitro fertilization (IVF) failure is common in the U.S., unlike in other developed nations. So, what makes IVIG so attractive?&nbsp;<\/p>\n\n\n\n<p>This article explains when IVIG may be an option for infertility. You will also learn about IVIG success rates, potential side effects, and treatment cost.&nbsp;<\/p>\n\n\n\n<div  id=\"call-to-action-2e2e0dbe9178189f424be0c35470af16\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet IVIG Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#A_Quick_Overview_of_Unexplained_Infertility\" >A Quick Overview of Unexplained Infertility<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#IVIG_for_Infertility_When_It_May_Be_an_Option\" >IVIG for Infertility: When It May Be an Option<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#IVIG_for_Infertility_What_Is_the_Success_Rate\" >IVIG for Infertility: What Is the Success Rate?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#The_Limitations_of_IVIG_for_Infertility\" >The Limitations of IVIG for Infertility<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#Side_Effects_and_Cost_of_IVIG_for_Pregnancy\" >Side Effects and Cost of IVIG for Pregnancy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/ivig-for-infertility-is-this-treatment-right-for-you\/#Key_Takeaways\" >Key Takeaways<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_Quick_Overview_of_Unexplained_Infertility\"><\/span>A Quick Overview of Unexplained Infertility<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Unexplained infertility is when you have repeated miscarriages or IVF failures. It may also be called recurrent pregnancy loss. The \u201cAmerican College of Obstetricians and Gynecologists\u201d defines recurrent pregnancy loss as having two or more miscarriages [<a href=\"https:\/\/www.acog.org\/womens-health\/faqs\/repeated-miscarriages#\">1<\/a>].&nbsp;<\/p>\n\n\n\n<p>In the US, nearly 13 in 100 women of childbearing age seek treatment for infertility annually [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9302705\/\">2<\/a>].<\/p>\n\n\n\n<p>Many factors can cause unexplained infertility. These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Abnormal uterus<\/li>\n\n\n\n<li>Thyroid disease<\/li>\n\n\n\n<li>Diabetes<\/li>\n\n\n\n<li>Abnormalities in the mother\u2019s immune system<\/li>\n\n\n\n<li>Unusual blood clotting in the mother<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_for_Infertility_When_It_May_Be_an_Option\"><\/span>IVIG for Infertility: When It May Be an Option<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>IVIG may be an option if miscarriage is due to the body\u2019s abnormal immune response to the embryo.&nbsp;&nbsp;<\/p>\n\n\n\n<p>In a normal pregnancy, your immune system accepts the embryo (even though it is 50% foreign tissue).&nbsp;<\/p>\n\n\n\n<p>But, when your immune system fails to accept the embryo, miscarriages can occur. When this happens, your body will produce more white blood cells (specifically natural killer cells) that attack the embryo.&nbsp;&nbsp;<\/p>\n\n\n\n<p>How IVIG works for infertility is not fully understood. Nonetheless, it is thought to reduce the risk of rejection by [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5395546\/\">3<\/a>]:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Neutralizing the antibodies that attack the embryo<\/li>\n\n\n\n<li>Reducing the number of natural killer cells<\/li>\n\n\n\n<li>Restoring the balance of specific immune cells involved in immune regulation<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"IVIG_for_Infertility_What_Is_the_Success_Rate\"><\/span>IVIG for Infertility: What Is the Success Rate?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>According to an extensive review, IVIG treatment was associated with a two-fold increase in live birth rate in women with repeated miscarriages and underlying immune diseases [<a href=\"https:\/\/aacijournal.biomedcentral.com\/articles\/10.1186\/s13223-022-00660-8\">4<\/a>].<\/p>\n\n\n\n<p>In women with repeated implantation failure, IVIG may improve the implantation and pregnancy rate [<a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/19396368.2017.1390007\">5<\/a>].<\/p>\n\n\n\n<p>A 2017 Cochrane review found higher pregnancy rates in IVIG-treated individuals (52%) than in untreated individuals (27%) [<a href=\"https:\/\/www.cochranelibrary.com\/central\/doi\/10.1002\/central\/CN-01412108\/full\">6<\/a>].<\/p>\n\n\n\n<p>The success rate depends on a woman\u2019s underlying immune disorder and the timing of the IVIG infusion and ovulation. For instance, it might be best to administer IVIG infusion before conception in women with increased natural killer cells [<a href=\"https:\/\/www.hindawi.com\/journals\/jir\/2020\/6672865\/\">7<\/a>].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_Limitations_of_IVIG_for_Infertility\"><\/span>The Limitations of IVIG for Infertility<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Despite promising results in numerous studies, IVIG is still an experimental therapy for infertility. Many professional organizations recommend against using IVIG for infertility.&nbsp;<\/p>\n\n\n\n<p>For instance, the Practice Committee of the American Society for Reproductive Medicine (2018) states that there is insufficient evidence to recommend IVIG for improving IVF outcomes.<\/p>\n\n\n\n<p>Likewise, a 2021 update by the American Academy of Pediatrics&nbsp;does not recommend IVIG for recurrent pregnancy loss and seeks further investigations [<a href=\"https:\/\/publications.aap.org\/neoreviews\/article-abstract\/22\/1\/e7\/92238\/Update-on-the-Use-of-Intravenous-Immunoglobulin-in?redirectedFrom=fulltext?autologincheck=redirected\">8<\/a>].<\/p>\n\n\n\n<p>Interestingly, the Korean Society for Reproductive Immunology recommends IVIG for women with recurrent pregnancy loss\/repeated implantation failure who also have underlying immune disorders [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5395546\/\">3<\/a>].<\/p>\n\n\n\n<div  id=\"call-to-action-93b106b61b4132c03e9b36bc97de834b\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tCan IVIG help?\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tFree IVIG Treatment Info\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects_and_Cost_of_IVIG_for_Pregnancy\"><\/span>Side Effects and Cost of IVIG for Pregnancy<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Severe side effects are infrequent and typically include infusion-related reactions. IVIG can also affect certain lab results.&nbsp;<\/p>\n\n\n\n<p>Common complaints can include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig-headaches\/\">Headache<\/a><\/li>\n\n\n\n<li>Fever&nbsp;<\/li>\n\n\n\n<li>Rash<\/li>\n<\/ul>\n\n\n\n<p>They are usually mild and manageable with&nbsp;<a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig-premedication-essential-things-to-know\/\">IVIG premedication<\/a>&nbsp;and slow infusion rates.&nbsp;<\/p>\n\n\n\n<p>IVIG therapy is expensive. A single course of therapy can cost $7,000 to $14,000 [<a href=\"https:\/\/www.fertstert.org\/article\/S0015-0282(06)03297-3\/pdf\">9<\/a>].&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Key_Takeaways\"><\/span>Key Takeaways<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>IVIG is a promising yet unproven treatment for infertility.&nbsp;<\/li>\n\n\n\n<li>Many experts consider it experimental and not medically necessary.<\/li>\n\n\n\n<li>IVIG might benefit a subgroup of women with specific immune disorders.<\/li>\n\n\n\n<li>More research is needed to fully understand its mechanism, optimal doses, and long-term effects.&nbsp;<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>The use of IVIG for infertility and in vitro fertilization (IVF) failure is common in the U.S., unlike in other developed nations. So, what makes IVIG so attractive? <\/p>\n<p>This article explains when IVIG may be an option for infertility.<\/p>","protected":false},"author":7,"featured_media":24693,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[7],"tags":[],"class_list":["post-24691","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ivig"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IVIG for Infertility: Is This Treatment Right for You? - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Should you get IVIG for Infertility? This article explores this topic. 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C\u00f4 theo h\u1ecdc t\u1ea1i \u0110\u1ea1i h\u1ecdc Midwestern, n\u01a1i c\u00f4 t\u1ed1t nghi\u1ec7p lo\u1ea1i xu\u1ea5t s\u1eafc. Ph\u1ea7n b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a c\u00f4 l\u00e0 \u0111\u1ec1 xu\u1ea5t thay \u0111\u1ed5i l\u1ed1i s\u1ed1ng, h\u01b0\u1edbng d\u1eabn b\u1ec7nh nh\u00e2n v\u1ec1 c\u00e1ch thu\u1ed1c c\u1ee7a h\u1ecd ho\u1ea1t \u0111\u1ed9ng v\u00e0 h\u01b0\u1edbng d\u1eabn c\u00e1c d\u01b0\u1ee3c s\u0129 t\u01b0\u01a1ng lai. L\u0129nh v\u1ef1c chuy\u00ean m\u00f4n c\u1ee7a c\u00f4 l\u00e0 d\u1ecbch v\u1ee5 kh\u00e1ch h\u00e0ng v\u00e0 ki\u1ebfn th\u1ee9c v\u1ec1 thu\u1ed1c chuy\u00ean khoa. T\u1eebng l\u00e0m vi\u1ec7c trong ng\u00e0nh d\u1ecbch v\u1ee5, c\u00f4 \u0111\u00e3 t\u00edch l\u0169y \u0111\u01b0\u1ee3c c\u00e1c k\u1ef9 n\u0103ng d\u1ecbch v\u1ee5 kh\u00e1ch h\u00e0ng c\u1ea7n thi\u1ebft \u0111\u1ec3 hi\u1ec3u nhu c\u1ea7u c\u1ee7a b\u1ec7nh nh\u00e2n. Ti\u1ebfn s\u0129 Leduc hi\u1ec7n \u0111ang h\u01b0\u1edbng d\u1eabn sinh vi\u00ean t\u1eeb \u0110\u1ea1i h\u1ecdc Marshall B. Ketchum, \u0110\u1ea1i h\u1ecdc Kansas v\u00e0 \u0110\u1ea1i h\u1ecdc Midwestern. Trong th\u1eddi gian r\u1ea3nh r\u1ed7i, c\u00f4 th\u00edch \u0111i du l\u1ecbch, l\u00e0m b\u00e1nh v\u00e0 l\u00e0m v\u01b0\u1eddn. Xem Ti\u1ec3u s\u1eed T\u00e1c gi\u1ea3","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/christine-leduc\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-300x200.jpg",300,200,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-768x512.jpg",768,512,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-600x400.jpg",600,400,true],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/02\/IVIG-for-Infertility-Is-This-Treatment-Right-for-You-new.jpg",1280,853,false]},"uagb_author_info":{"display_name":"Dr. Christine Leduc, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/christine-leduc\/"},"uagb_comment_info":0,"uagb_excerpt":"The use of IVIG for infertility and in vitro fertilization (IVF) failure is common in the U.S., unlike in other developed nations. 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