{"id":23134,"date":"2023-08-03T11:31:47","date_gmt":"2023-08-03T18:31:47","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=23134"},"modified":"2026-03-19T14:50:08","modified_gmt":"2026-03-19T21:50:08","slug":"reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/","title":{"rendered":"Reblozyl (Luspatercept): Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 b\u1ec7nh thi\u1ebfu m\u00e1u trong c\u00e1c b\u1ec7nh r\u1ed1i lo\u1ea1n m\u00e1u"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Reblozyl, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi b\u1eb1ng t\u00ean chung l\u00e0 \u201cluspatercept\u201d, l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c theo toa \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng thi\u1ebfu m\u00e1u (s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u th\u1ea5p) \u1edf b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n v\u1ec1 m\u00e1u nh\u01b0 <a href=\"https:\/\/www.cancer.gov\/types\/myeloproliferative\/patient\/myelodysplastic-treatment-pdq#:~:text=Myelodysplastic%20syndromes%20are%20a%20group,blood%20cells%20and%20bone%20marrow.\">h\u1ed9i ch\u1ee9ng lo\u1ea1n s\u1ea3n t\u1ee7y<\/a> (MDS) v\u00e0 <a href=\"https:\/\/medlineplus.gov\/genetics\/condition\/beta-thalassemia\/#:~:text=Beta%20thalassemia%20is%20a%20blood,oxygen%20levels%20in%20the%20body.\">b\u1ec7nh thalassemia beta<\/a>.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl thu\u1ed9c nh\u00f3m thu\u1ed1c \u201cthu\u1ed1c l\u00e0m tr\u01b0\u1edfng th\u00e0nh h\u1ed3ng c\u1ea7u\u201d (EMA) c\u00f3 t\u00e1c d\u1ee5ng c\u1ea3i thi\u1ec7n qu\u00e1 tr\u00ecnh t\u1ea1o h\u1ed3ng c\u1ea7u (m\u1ed9t qu\u00e1 tr\u00ecnh li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u tr\u01b0\u1edfng th\u00e0nh). <\/span><span style=\"font-weight: 400;\">N\u00f3i c\u00e1ch kh\u00e1c, n\u00f3 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u (RBC) tr\u01b0\u1edfng th\u00e0nh v\u00e0 ho\u1ea1t \u0111\u1ed9ng t\u1ed1t h\u01a1n, \u0111\u1ed3ng th\u1eddi cho ph\u00e9p c\u00e1c t\u1ebf b\u00e0o non tr\u01b0\u1edfng th\u00e0nh v\u00e0 ho\u1ea1t \u0111\u1ed9ng \u0111\u00fang c\u00e1ch. \u0110i\u1ec1u n\u00e0y c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u v\u00e0 t\u0103ng l\u01b0\u1ee3ng hemoglobin (Hgb) trong c\u01a1 th\u1ec3, gi\u00fap c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng thi\u1ebfu m\u00e1u do c\u00f3 nhi\u1ec1u h\u1ed3ng c\u1ea7u tr\u01b0\u1edfng th\u00e0nh h\u01a1n trong m\u00e1u.<\/span><span style=\"font-weight: 400;\"> Reblozyl l\u00e0 lo\u1ea1i thu\u1ed1c duy nh\u1ea5t trong nh\u00f3m n\u00e0y <\/span><span style=\"font-weight: 400;\">\u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn<\/span><span style=\"font-weight: 400;\"> \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thi\u1ebfu m\u00e1u \u1edf b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh c\u1ea7n truy\u1ec1n h\u1ed3ng c\u1ea7u (RBC) th\u01b0\u1eddng xuy\u00ean ho\u1eb7c nh\u1eefng ng\u01b0\u1eddi b\u1ecb thi\u1ebfu m\u00e1u kh\u00f4ng \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi c\u00e1c t\u00e1c nh\u00e2n l\u00e0m tr\u01b0\u1edfng th\u00e0nh h\u1ed3ng c\u1ea7u kh\u00e1c.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl ch\u1ec9 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c mua theo \u0111\u01a1n c\u1ee7a b\u00e1c s\u0129 v\u00e0 \u0111\u01b0\u1ee3c \u0111\u00f3ng g\u00f3i d\u01b0\u1edbi d\u1ea1ng l\u1ecd \u0111\u01a1n li\u1ec1u \u0111\u1ec3 ti\u00eam v\u1edbi hai h\u00e0m l\u01b0\u1ee3ng kh\u00e1c nhau: 25 mg v\u00e0 75 mg.&nbsp;<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#What_Is_Reblozyl_Used_To_Treat\" >Thu\u1ed1c Reblozyl \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#How_Does_Reblozyl_Work\" >Reblozyl ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Dosage_Form_and_Strength\" >D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Reconstitution_of_Reblozyl_Powder_in_Sterile_Water\" >T\u00e1i t\u1ea1o b\u1ed9t Reblozyl trong n\u01b0\u1edbc v\u00f4 tr\u00f9ng&nbsp;<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Reblozyl_Dosing_Information\" >Th\u00f4ng tin li\u1ec1u d\u00f9ng Reblozyl<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Dose_Modification_for_B-thalassemia_Patients\" >\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u cho b\u1ec7nh nh\u00e2n thalassemia B&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Dose_Modification_for_MDS_Patients\" >\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u cho b\u1ec7nh nh\u00e2n MDS&nbsp;<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#How_Is_Reblozyl_Given\" >Reblozyl \u0111\u01b0\u1ee3c cung c\u1ea5p nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Is_Reblozyl_a_Form_of_Chemotherapy\" >Reblozyl c\u00f3 ph\u1ea3i l\u00e0 m\u1ed9t d\u1ea1ng h\u00f3a tr\u1ecb li\u1ec7u kh\u00f4ng?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Possible_Side_Effects_of_Reblozyl\" >T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra c\u1ee7a Reblozyl<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Precaution\" >Th\u1eadn tr\u1ecdng<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/reblozyl-luspatercept-an-effective-treatment-for-anemia-in-blood-disorders\/#Cost\" >Tr\u1ecb gi\u00e1<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Reblozyl_Used_To_Treat\"><\/span>Thu\u1ed1c Reblozyl \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn l\u00e0 li\u1ec7u ph\u00e1p h\u00e0ng \u0111\u1ea7u \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thi\u1ebfu m\u00e1u li\u00ean quan \u0111\u1ebfn c\u00e1c r\u1ed1i lo\u1ea1n m\u00e1u sau \u0111\u00e2y \u1edf ng\u01b0\u1eddi l\u1edbn:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>B\u1ec7nh thalassemia beta \u2013 <\/b><span style=\"font-weight: 400;\">M\u1ed9t d\u1ea1ng r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n hi\u1ebfm g\u1eb7p, trong \u0111\u00f3 b\u1ec7nh nh\u00e2n b\u1ecb thi\u1ebfu ho\u1eb7c khi\u1ebfm khuy\u1ebft gen t\u1ea1o ra protein beta globin. Protein n\u00e0y l\u00e0 m\u1ed9t th\u00e0nh ph\u1ea7n c\u1ee7a protein hemoglobin c\u00f3 trong h\u1ed3ng c\u1ea7u, c\u00f3 ch\u1ee9c n\u0103ng v\u1eadn chuy\u1ec3n oxy \u0111i kh\u1eafp c\u01a1 th\u1ec3. <\/span><span style=\"font-weight: 400;\">Khi b\u1ea1n m\u1eafc b\u1ec7nh thalassemia, c\u01a1 th\u1ec3 b\u1ea1n s\u1ebd s\u1ea3n xu\u1ea5t \u00edt hemoglobin h\u01a1n b\u00ecnh th\u01b0\u1eddng v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u nh\u1eb9 ho\u1eb7c n\u1eb7ng.<\/span><span style=\"font-weight: 400;\"> Khi n\u1ed3ng \u0111\u1ed9 hemoglobin th\u1ea5p, n\u00f3 c\u00f3 th\u1ec3 g\u00e2y ra t\u00ecnh tr\u1ea1ng y\u1ebfu c\u01a1, m\u1ec7t m\u1ecfi v\u00e0 nhi\u1ec1u bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng h\u01a1n. <\/span><span style=\"font-weight: 400;\">Reblozyl \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh m\u1eafc b\u1ec7nh thalassemia beta c\u1ea7n truy\u1ec1n h\u1ed3ng c\u1ea7u th\u01b0\u1eddng xuy\u00ean.&nbsp;<\/span><\/li>\n\n\n\n<li><b>H\u1ed9i ch\u1ee9ng lo\u1ea1n s\u1ea3n t\u1ee7y (MDS) <\/b><span style=\"font-weight: 400;\">\u2013 m\u1ed9t nh\u00f3m ung th\u01b0 trong \u0111\u00f3 c\u00e1c t\u1ebf b\u00e0o t\u1ea1o m\u00e1u ch\u01b0a tr\u01b0\u1edfng th\u00e0nh trong t\u1ee7y x\u01b0\u01a1ng kh\u00f4ng ph\u00e1t tri\u1ec3n (tr\u01b0\u1edfng th\u00e0nh) ho\u1eb7c kh\u00f4ng tr\u1edf th\u00e0nh c\u00e1c t\u1ebf b\u00e0o ch\u1ee9c n\u0103ng kh\u1ecfe m\u1ea1nh. C\u00e1c t\u1ebf b\u00e0o th\u01b0\u1eddng b\u1ecb \u1ea3nh h\u01b0\u1edfng nh\u1ea5t b\u1edfi MDS l\u00e0 h\u1ed3ng c\u1ea7u. <\/span><span style=\"font-weight: 400;\">Khi c\u00e1c t\u1ebf b\u00e0o ch\u01b0a tr\u01b0\u1edfng th\u00e0nh kh\u00f4ng ho\u1ea1t \u0111\u1ed9ng \u0111\u00fang ch\u1ee9c n\u0103ng, \u0111i\u1ec1u n\u00e0y s\u1ebd l\u00e0m gi\u1ea3m kh\u00f4ng gian h\u00ecnh th\u00e0nh c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u (WBC), h\u1ed3ng c\u1ea7u v\u00e0 ti\u1ec3u c\u1ea7u kh\u1ecfe m\u1ea1nh trong t\u1ee7y x\u01b0\u01a1ng. Thi\u1ebfu m\u00e1u, nhi\u1ec5m tr\u00f9ng ho\u1eb7c d\u1ec5 ch\u1ea3y m\u00e1u c\u00f3 th\u1ec3 x\u1ea3y ra do s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o m\u00e1u kh\u1ecfe m\u1ea1nh \u00edt h\u01a1n.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p>B\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc MDS ho\u1eb7c c\u00e1c ph\u00e2n nh\u00f3m c\u1ee7a n\u00f3 \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh lo\u1ea1n s\u1ea3n t\u1ee7y\/t\u0103ng sinh t\u1ee7y v\u1edbi <a href=\"https:\/\/ashpublications.org\/blood\/article\/119\/24\/5674\/30309\/Prognostic-irrelevance-of-ring-sideroblast\">nguy\u00ean b\u00e0o s\u1eaft v\u00f2ng<\/a> (MDS-RS) ho\u1eb7c b\u1ecb thi\u1ebfu m\u00e1u li\u00ean quan \u0111\u1ebfn t\u0103ng ti\u1ec3u c\u1ea7u \u0111\u00e3 th\u1ea5t b\u1ea1i trong <a href=\"https:\/\/en.wikipedia.org\/wiki\/Erythropoiesis-stimulating_agent\">ch\u1ea5t k\u00edch th\u00edch t\u1ea1o h\u1ed3ng c\u1ea7u<\/a> (EPO) v\u00e0 c\u1ea7n hai ho\u1eb7c nhi\u1ec1u \u0111\u01a1n v\u1ecb RBC (\u0111\u1ec3 truy\u1ec1n m\u00e1u) trong h\u01a1n 8 tu\u1ea7n c\u00f3 th\u1ec3 \u0111\u1ee7 \u0111i\u1ec1u ki\u1ec7n \u0111\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Rebloyzl.<br><b><\/b><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ee5c \u0111\u00edch s\u1eed d\u1ee5ng Reblozyl \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n n\u00eau tr\u00ean l\u00e0 \u0111\u1ec3 gi\u1ea3m s\u1ed1 l\u1ea7n truy\u1ec1n m\u00e1u v\u00e0 c\u00e1c bi\u1ebfn ch\u1ee9ng li\u00ean quan \u0111\u1ebfn truy\u1ec1n m\u00e1u. <\/span><span style=\"font-weight: 400;\">Tuy nhi\u00ean, \u0111i\u1ec1u quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd l\u00e0 Reblozyl kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thay th\u1ebf cho truy\u1ec1n h\u1ed3ng c\u1ea7u \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u1ea7n \u0111i\u1ec1u tr\u1ecb thi\u1ebfu m\u00e1u ngay l\u1eadp t\u1ee9c. Ng\u01b0\u1eddi ta c\u0169ng ch\u01b0a bi\u1ebft li\u1ec7u Reblozyl c\u00f3 hi\u1ec7u qu\u1ea3 ho\u1eb7c an to\u00e0n cho tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i hay kh\u00f4ng.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_Reblozyl_Work\"><\/span>Reblozyl ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Trong \u0111i\u1ec1u ki\u1ec7n b\u00ecnh th\u01b0\u1eddng, c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u non s\u1ebd tr\u01b0\u1edfng th\u00e0nh v\u00e0 ph\u00e1t tri\u1ec3n th\u00e0nh c\u00e1c t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh, c\u00f3 ch\u1ee9c n\u0103ng trong t\u1ee7y x\u01b0\u01a1ng th\u00f4ng qua qu\u00e1 tr\u00ecnh t\u1ea1o h\u1ed3ng c\u1ea7u. T\u1ea1o h\u1ed3ng c\u1ea7u l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh n\u0103ng \u0111\u1ed9ng b\u1eaft \u0111\u1ea7u b\u1eb1ng s\u1ef1 t\u0103ng sinh c\u1ee7a <a href=\"https:\/\/profiles.umassmed.edu\/display\/106571#:~:text=The%20cells%20in%20the%20erythroid,to%20mature%20RED%20BLOOD%20CELLS.\">ti\u1ec1n th\u00e2n h\u1ed3ng c\u1ea7u<\/a> v\u00e0 k\u1ebft th\u00fac b\u1eb1ng s\u1ef1 tr\u01b0\u1edfng th\u00e0nh c\u1ee7a c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u kh\u1ecfe m\u1ea1nh trong t\u1ee7y x\u01b0\u01a1ng. C\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u tr\u01b0\u1edfng th\u00e0nh sau \u0111\u00f3 di chuy\u1ec3n v\u00e0o h\u1ec7 tu\u1ea7n ho\u00e0n m\u00e1u v\u00e0 th\u1ef1c hi\u1ec7n ch\u1ee9c n\u0103ng v\u1eadn chuy\u1ec3n oxy \u0111i kh\u1eafp c\u01a1 th\u1ec3.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Qu\u00e1 tr\u00ecnh t\u1ea1o h\u1ed3ng c\u1ea7u kh\u00f4ng hi\u1ec7u qu\u1ea3 d\u1eabn \u0111\u1ebfn s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u th\u1ea5p h\u01a1n v\u00e0 <\/span><span style=\"font-weight: 400;\">r\u1ee7i ro cao h\u01a1n<\/span><span style=\"font-weight: 400;\"> thi\u1ebfu m\u00e1u. Qu\u00e1 tr\u00ecnh t\u1ea1o h\u1ed3ng c\u1ea7u kh\u00f4ng hi\u1ec7u qu\u1ea3 x\u1ea3y ra do ho\u1ea1t \u0111\u1ed9ng qu\u00e1 m\u1ee9c c\u1ee7a con \u0111\u01b0\u1eddng truy\u1ec1n t\u00edn hi\u1ec7u Smad2\/3 l\u00e0m ch\u1eadm ho\u1eb7c d\u1eebng qu\u00e1 tr\u00ecnh tr\u01b0\u1edfng th\u00e0nh b\u00ecnh th\u01b0\u1eddng c\u1ee7a h\u1ed3ng c\u1ea7u \u1edf b\u1ec7nh nh\u00e2n thalassemia B v\u00e0 MDS.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi b\u1eb1ng t\u00ean chung: <\/span><b>\u201c<\/b><b>luspatercept,\u201d<\/b> <span style=\"font-weight: 400;\">T\u00f4i<\/span><span style=\"font-weight: 400;\">sa t\u00e1i t\u1ed5 h\u1ee3p <\/span><span style=\"font-weight: 400;\">s\u1ef1 h\u1ee3p nh\u1ea5t<\/span><span style=\"font-weight: 400;\"> protein \u0111\u00f3 <\/span><span style=\"font-weight: 400;\">li\u00ean k\u1ebft \u0111\u01b0\u1ee3c ch\u1ecdn <a href=\"https:\/\/www.rndsystems.com\/research-area\/tgf--beta-superfamily\">y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng chuy\u1ec3n \u0111\u1ed5i-<\/a><\/span><span style=\"font-weight: 400;\">C\u00e1c ph\u1ed1i t\u1eed si\u00eau h\u1ecd \u03b2 (TGF-\u03b2). Khi li\u00ean k\u1ebft v\u1edbi c\u00e1c ph\u1ed1i t\u1eed n\u1ed9i sinh \u0111\u1eb7c hi\u1ec7u, n\u00f3 s\u1ebd ng\u0103n ch\u1eb7n t\u00edn hi\u1ec7u Smad2\/3, d\u1eabn \u0111\u1ebfn s\u1ef1 tr\u01b0\u1edfng th\u00e0nh h\u1ed3ng c\u1ea7u trong t\u1ee7y x\u01b0\u01a1ng v\u00e0 d\u1eabn \u0111\u1ebfn<\/span><span style=\"font-weight: 400;\"> s\u1ef1 ph\u00e1t tri\u1ec3n b\u00ecnh th\u01b0\u1eddng c\u1ee7a h\u1ed3ng c\u1ea7u.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosage_Form_and_Strength\"><\/span>D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl c\u00f3 d\u1ea1ng b\u1ed9t \u0111\u00f4ng kh\u00f4 v\u00f4 tr\u00f9ng, m\u00e0u tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0 v\u1edbi h\u00e0m l\u01b0\u1ee3ng 25 mg v\u00e0 75 mg.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Reconstitution_of_Reblozyl_Powder_in_Sterile_Water\"><\/span><b>T\u00e1i t\u1ea1o b\u1ed9t Reblozyl trong n\u01b0\u1edbc v\u00f4 tr\u00f9ng&nbsp;<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">M\u1ed9t l\u1ecd thu\u1ed1c li\u1ec1u \u0111\u01a1n 25 mg \u0111\u01b0\u1ee3c pha v\u1edbi 0,68 ml n\u01b0\u1edbc v\u00f4 tr\u00f9ng. <\/span><span style=\"font-weight: 400;\">M\u1ed7i l\u1ecd li\u1ec1u \u0111\u01a1n 25 mg s\u1ebd cung c\u1ea5p \u00edt nh\u1ea5t 0,5 ml luspatercept 50 mg\/ml.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ed9t l\u1ecd thu\u1ed1c li\u1ec1u \u0111\u01a1n 75 mg \u0111\u01b0\u1ee3c pha v\u1edbi 1,6 ml n\u01b0\u1edbc v\u00f4 tr\u00f9ng. <\/span><span style=\"font-weight: 400;\">M\u1ed7i l\u1ecd li\u1ec1u \u0111\u01a1n 75 mg s\u1ebd cung c\u1ea5p \u00edt nh\u1ea5t 1,5 ml luspatercept 50 mg\/ml.<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u00ean s\u1eed d\u1ee5ng \u1ed1ng ti\u00eam c\u00f3 v\u1ea1ch chia \u0111\u1ec3 ti\u00eam li\u1ec1u l\u01b0\u1ee3ng ch\u00ednh x\u00e1c.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Reblozyl_Dosing_Information\"><\/span>Th\u00f4ng tin li\u1ec1u d\u00f9ng Reblozyl<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u d\u00f9ng Reblozyl \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh d\u1ef1a tr\u00ean c\u00e2n n\u1eb7ng, huy\u1ebft s\u1eafc t\u1ed1 v\u00e0 h\u1ed3 s\u01a1 truy\u1ec1n m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n. Li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o c\u1ee7a Reblozyl l\u00e0 1 mg\/kg, d\u00f9ng 3 tu\u1ea7n m\u1ed9t l\u1ea7n.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dose_Modification_for_B-thalassemia_Patients\"><\/span><b>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u cho b\u1ec7nh nh\u00e2n thalassemia B&nbsp;<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u l\u01b0\u1ee3ng trong t\u01b0\u01a1ng lai \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo c\u00e1c \u0111i\u1ec1u ki\u1ec7n sau:&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">N\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7 v\u1edbi li\u1ec1u ban \u0111\u1ea7u (1 mg\/kg <\/span><span style=\"font-weight: 400;\">3 tu\u1ea7n m\u1ed9t l\u1ea7n<\/span><span style=\"font-weight: 400;\">) v\u00e0 kh\u00f4ng \u0111\u1ea1t \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 gi\u1ea3m truy\u1ec1n RBC sau hai l\u1ea7n \u0111i\u1ec1u tr\u1ecb (\u00edt nh\u1ea5t 2 li\u1ec1u li\u00ean ti\u1ebfp\/6 tu\u1ea7n), c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 1,25 mg\/kg sau m\u1ed7i 3 tu\u1ea7n <\/span><span style=\"font-weight: 400;\">(li\u1ec1u t\u1ed1i \u0111a)<\/span><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ng\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7 v\u1edbi li\u1ec1u \u0111i\u1ec1u ch\u1ec9nh (1,25 mg\/kg) v\u00e0 kh\u00f4ng gi\u1ea3m \u0111\u01b0\u1ee3c l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u truy\u1ec1n sau ba l\u1ea7n \u0111i\u1ec1u tr\u1ecb (3 li\u1ec1u\/9 tu\u1ea7n).&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dose_Modification_for_MDS_Patients\"><\/span><b>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u cho b\u1ec7nh nh\u00e2n MDS&nbsp;<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u l\u01b0\u1ee3ng trong t\u01b0\u01a1ng lai \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo c\u00e1c \u0111i\u1ec1u ki\u1ec7n sau:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">N\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7 v\u1edbi li\u1ec1u ban \u0111\u1ea7u (1 mg\/kg) v\u00e0 kh\u00f4ng gi\u1ea3m \u0111\u01b0\u1ee3c l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u truy\u1ec1n sau hai l\u1ea7n \u0111i\u1ec1u tr\u1ecb (2 li\u1ec1u\/6 tu\u1ea7n), th\u00ec t\u0103ng li\u1ec1u l\u00ean 1,33 mg\/kg sau m\u1ed7i 3 tu\u1ea7n.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">N\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7 v\u1edbi li\u1ec1u \u0111i\u1ec1u ch\u1ec9nh (1,33 mg\/kg) v\u00e0 kh\u00f4ng gi\u1ea3m \u0111\u01b0\u1ee3c l\u01b0\u1ee3ng truy\u1ec1n RBC sau hai l\u1ea7n \u0111i\u1ec1u tr\u1ecb (2 li\u1ec1u\/6 tu\u1ea7n), th\u00ec t\u0103ng li\u1ec1u l\u00ean 1,75 mg\/kg sau m\u1ed7i 3 tu\u1ea7n.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ng\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7 v\u1edbi li\u1ec1u \u0111i\u1ec1u ch\u1ec9nh (1,75 mg\/kg) v\u00e0 kh\u00f4ng gi\u1ea3m \u0111\u01b0\u1ee3c l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u truy\u1ec1n sau ba l\u1ea7n \u0111i\u1ec1u tr\u1ecb (3 li\u1ec1u\/9 tu\u1ea7n).&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Reblozyl_Given\"><\/span>Reblozyl \u0111\u01b0\u1ee3c cung c\u1ea5p nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c Reblozyl ch\u1ec9 \u0111\u01b0\u1ee3c \u0111\u01b0a ra <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/ivig\/scig-vs-ivig\/\">d\u01b0\u1edbi da<\/a> (d\u01b0\u1edbi da) ba tu\u1ea7n m\u1ed9t l\u1ea7n.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n s\u1ebd \u0111\u01b0\u1ee3c ti\u00eam Reblozyl d\u01b0\u1edbi da b\u1ee5ng, c\u00e1nh tay tr\u00ean ho\u1eb7c \u0111\u00f9i. Thu\u1ed1c n\u00e0y s\u1ebd \u0111\u01b0\u1ee3c ti\u00eam d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a nh\u00e2n vi\u00ean y t\u1ebf ho\u1eb7c \u0111i\u1ec1u d\u01b0\u1ee1ng c\u00f3 kinh nghi\u1ec7m \u0111\u1ec3 tr\u00e1nh c\u00e1c bi\u1ebfn ch\u1ee9ng sau n\u00e0y.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Is_Reblozyl_a_Form_of_Chemotherapy\"><\/span>Reblozyl c\u00f3 ph\u1ea3i l\u00e0 m\u1ed9t d\u1ea1ng h\u00f3a tr\u1ecb li\u1ec7u kh\u00f4ng?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Reblozyl kh\u00f4ng ph\u1ea3i l\u00e0 m\u1ed9t d\u1ea1ng h\u00f3a tr\u1ecb li\u1ec7u m\u00e0 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c theo toa d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng thi\u1ebfu m\u00e1u li\u00ean quan \u0111\u1ebfn MDS v\u00e0 b\u1ec7nh thalassemia beta \u1edf ng\u01b0\u1eddi l\u1edbn.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Possible_Side_Effects_of_Reblozyl\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra c\u1ee7a Reblozyl<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain.jpg\" alt=\"Asian woman feeling stomachache as a side effect of Reblozyl\" class=\"wp-image-23137\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/08\/woman-stomach-pain-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Reblozyl bao g\u1ed3m<\/span><span style=\"font-weight: 400;\">:&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">C\u1ea3m th\u1ea5y m\u1ec7t m\u1ecfi<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au c\u01a1 ho\u1eb7c x\u01b0\u01a1ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ch\u00f3ng m\u1eb7t<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ti\u00eau ch\u1ea3y<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au d\u1ea1 d\u00e0y (b\u1ee5ng)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au kh\u1edbp (arthralgia)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Bu\u1ed3n n\u00f4n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ho<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">D\u1ea5u hi\u1ec7u c\u1ee7a c\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00e1c d\u1ea5u hi\u1ec7u gi\u1ed1ng c\u00fam<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 x\u1ea3y ra bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">C\u1ee5c m\u00e1u \u0111\u00f4ng (huy\u1ebft kh\u1ed1i\/thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i)<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Nguy c\u01a1 c\u00f3 th\u1ec3 cao h\u01a1n \u1edf nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 c\u1eaft b\u1ecf l\u00e1 l\u00e1ch ho\u1eb7c d\u00f9ng thu\u1ed1c tr\u00e1nh thai ho\u1eb7c li\u1ec7u ph\u00e1p thay th\u1ebf hormone.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i g\u1ecdi cho nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe ho\u1eb7c t\u00ecm ki\u1ebfm s\u1ef1 tr\u1ee3 gi\u00fap y t\u1ebf ngay l\u1eadp t\u1ee9c n\u1ebfu b\u1ea1n g\u1eb7p b\u1ea5t k\u1ef3 tri\u1ec7u ch\u1ee9ng n\u00e0o sau \u0111\u00e2y:<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110au ng\u1ef1c<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Kh\u00f3 th\u1edf ho\u1eb7c th\u1edf g\u1ea5p<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u1edf ch\u00e2n, c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 s\u01b0ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ed9t c\u00e1nh tay ho\u1eb7c ch\u00e2n nh\u1ee3t nh\u1ea1t ho\u1eb7c l\u1ea1nh<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u00ea li\u1ec7t ho\u1eb7c y\u1ebfu \u0111\u1ed9t ng\u1ed9t trong th\u1eddi gian ng\u1eafn ho\u1eb7c k\u00e9o d\u00e0i trong m\u1ed9t th\u1eddi gian d\u00e0i, \u0111\u1eb7c bi\u1ec7t l\u00e0 n\u1ebfu ch\u1ec9 \u1edf m\u1ed9t b\u00ean c\u01a1 th\u1ec3<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u d\u1eef d\u1ed9i ho\u1eb7c l\u00fa l\u1eabn<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ch\u00f3ng m\u1eb7t \u0111\u1ed9t ng\u1ed9t ho\u1eb7c kh\u00f3 nh\u00ecn, \u0111i l\u1ea1i, n\u00f3i ho\u1eb7c gi\u1eef th\u0103ng b\u1eb1ng&nbsp;<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Huy\u1ebft \u00e1p cao (t\u0103ng huy\u1ebft \u00e1p)<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 c\u1ee7a b\u1ea1n s\u1ebd ki\u1ec3m tra huy\u1ebft \u00e1p c\u1ee7a b\u1ea1n tr\u01b0\u1edbc khi b\u1ea1n nh\u1eadn li\u1ec1u Reblozyl<\/span><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><span style=\"font-weight: 400;\"><a href=\"https:\/\/radiopaedia.org\/articles\/extramedullary-haematopoiesis?lang=us\">T\u1ea1o m\u00e1u ngo\u00e0i t\u1ee7y (EMH)<\/a> kh\u1ed1i l\u01b0\u1ee3ng<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i g\u1ecdi cho nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe ho\u1eb7c t\u00ecm ki\u1ebfm s\u1ef1 tr\u1ee3 gi\u00fap y t\u1ebf ngay l\u1eadp t\u1ee9c n\u1ebfu b\u1ea1n g\u1eb7p b\u1ea5t k\u1ef3 tri\u1ec7u ch\u1ee9ng n\u00e0o sau \u0111\u00e2y:<\/span>\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110au l\u01b0ng d\u1eef d\u1ed9i<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u00ea li\u1ec7t, y\u1ebfu ho\u1eb7c m\u1ea5t kh\u1ea3 n\u0103ng v\u1eadn \u0111\u1ed9ng t\u1ef1 nguy\u1ec7n \u1edf ch\u00e2n, tay, b\u00e0n tay ho\u1eb7c b\u00e0n ch\u00e2n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ea5t kh\u1ea3 n\u0103ng ki\u1ec3m so\u00e1t ru\u1ed9t v\u00e0 b\u00e0ng quang&nbsp;<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precaution\"><\/span>Th\u1eadn tr\u1ecdng<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec7u ph\u00e1p Reblozyl kh\u00f4ng d\u00e0nh cho t\u1ea5t c\u1ea3 m\u1ecdi ng\u01b0\u1eddi. B\u1ea1n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p Reblozyl n\u1ebfu b\u1ea1n:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">L\u00e0 <\/span><b>c\u00f3 thai<\/b><span style=\"font-weight: 400;\">Reblozyl c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi. Do \u0111\u00f3, khuy\u1ebfn c\u00e1o tr\u00e1nh s\u1eed d\u1ee5ng Reblozyl trong th\u1eddi k\u1ef3 mang thai.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">L\u00e0 <\/span><b>\u0111ang c\u00f3 k\u1ebf ho\u1ea1ch mang thai<\/b><span style=\"font-weight: 400;\">. S\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai ho\u1eb7c bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb <\/span><span style=\"font-weight: 400;\">v\u00e0 \u00edt nh\u1ea5t 3 th\u00e1ng sau li\u1ec1u cu\u1ed1i c\u00f9ng.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">L\u00e0<\/span><b> \u0111ang cho con b\u00fa ho\u1eb7c d\u1ef1 \u0111\u1ecbnh cho con b\u00fa<\/b><span style=\"font-weight: 400;\">. V\u00ec d\u1eef li\u1ec7u v\u1ec1 s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a Reblozyl trong s\u1eefa m\u1eb9 c\u00f2n h\u1ea1n ch\u1ebf n\u00ean kh\u00f4ng khuy\u1ebfn kh\u00edch cho con b\u00fa trong khi ti\u00eam Reblozyl v\u00e0 <\/span><span style=\"font-weight: 400;\">trong \u00edt nh\u1ea5t 3 th\u00e1ng sau li\u1ec1u cu\u1ed1i c\u00f9ng.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">B\u1ecb d\u1ecb \u1ee9ng v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a Reblozyl.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00f3 ho\u1eb7c \u0111\u00e3 t\u1eebng c\u00f3 ti\u1ec1n s\u1eed t\u0103ng huy\u1ebft \u00e1p v\u00e0 <\/span><span style=\"font-weight: 400;\">kh\u1ed1i u t\u1ea1o m\u00e1u ngo\u00e0i t\u1ee7y (EMH).&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110\u00e3 c\u1eaft l\u00e1ch (c\u1eaft b\u1ecf l\u00e1 l\u00e1ch).<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00f3 ho\u1eb7c \u0111\u00e3 t\u1eebng b\u1ecb l\u00e1ch ho\u1eb7c gan to.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">D\u00f9ng thu\u1ed1c b\u1ed5 t\u1ed5ng h\u1ee3p, thu\u1ed1c th\u1ea3o d\u01b0\u1ee3c ho\u1eb7c thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>Tr\u1ecb gi\u00e1<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Chi ph\u00ed c\u1ee7a lo\u1ea1i thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 thay \u0111\u1ed5i v\u00e0 ph\u1ee5 thu\u1ed9c v\u00e0o hi\u1ec7u thu\u1ed1c b\u1ea1n \u0111\u1ebfn. Vui l\u00f2ng <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/financial-assistance\/\">li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i<\/a> n\u1ebfu b\u1ea1n quan t\u00e2m \u0111\u1ebfn h\u1ed7 tr\u1ee3 \u0111\u1ed3ng thanh to\u00e1n cho Reblozyl.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Reblozyl, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi b\u1eb1ng t\u00ean chung l\u00e0 \u201cluspatercept\u201d, l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c theo toa \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng thi\u1ebfu m\u00e1u (s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u th\u1ea5p) \u1edf b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh m\u1eafc c\u00e1c ch\u1ee9ng r\u1ed1i lo\u1ea1n m\u00e1u nh\u01b0 h\u1ed9i ch\u1ee9ng lo\u1ea1n s\u1ea3n t\u1ee7y (MDS) v\u00e0 b\u1ec7nh thalassemia beta.\u00a0<\/p>","protected":false},"author":28,"featured_media":23135,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[34],"class_list":["post-23134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-dr-jenna-nguyen"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Reblozyl (Luspatercept): An Effective Treatment for Anemia in Blood Disorders - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn about Reblozyl and how it treats anemia. 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