{"id":22936,"date":"2023-06-23T12:40:04","date_gmt":"2023-06-23T19:40:04","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=22936"},"modified":"2026-03-19T14:45:21","modified_gmt":"2026-03-19T21:45:21","slug":"otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/","title":{"rendered":"Otezla: M\u1ed9t l\u1ef1a ch\u1ecdn phi sinh h\u1ecdc hi\u1ec7u qu\u1ea3 \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng b\u00e1m v\u00e0 vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng, c\u00e1c li\u1ec7u ph\u00e1p t\u1ea1i ch\u1ed7 nh\u01b0 kem ho\u1eb7c thu\u1ed1c m\u1ee1 \u0111\u00f4i khi kh\u00f4ng \u0111\u1ee7. B\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh su\u1ed1t \u0111\u1eddi, bao g\u1ed3m c\u00e1c chu k\u1ef3 b\u00f9ng ph\u00e1t v\u00e0 thuy\u00ean gi\u1ea3m. Nhi\u1ec1u b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng c\u0169ng c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n th\u00e0nh vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn, g\u00e2y \u0111au, s\u01b0ng v\u00e0 vi\u00eam xung quanh kh\u1edbp.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">V\u00e0o n\u0103m 2014, m\u1ed9t lo\u1ea1i thu\u1ed1c c\u00f3 t\u00ean l\u00e0 Otezla \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn b\u1edfi <a href=\"https:\/\/www.fda.gov\/\">C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3<\/a> (FDA) cho c\u1ea3 b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng b\u00e1m v\u00e0 vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn. N\u0103m 2019, Otezla \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c th\u00eam s\u1ef1 ch\u1ea5p thu\u1eadn c\u1ee7a FDA cho m\u1ed9t t\u00ecnh tr\u1ea1ng g\u1ecdi l\u00e0 b\u1ec7nh Beh\u00e7et, m\u1ed9t r\u1ed1i lo\u1ea1n t\u1ef1 mi\u1ec5n d\u1ecbch c\u00f3 th\u1ec3 g\u00e2y lo\u00e9t mi\u1ec7ng, lo\u00e9t sinh d\u1ee5c v\u00e0 vi\u00eam \u1edf m\u1ed9t s\u1ed1 b\u1ed9 ph\u1eadn c\u1ee7a c\u01a1 th\u1ec3.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Trong b\u00e0i vi\u1ebft n\u00e0y, ch\u00fang ta s\u1ebd t\u00ecm hi\u1ec3u c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng, hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a Otezla, c\u0169ng nh\u01b0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ti\u1ec1m \u1ea9n, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 nh\u1eefng c\u00e2n nh\u1eafc d\u00e0nh cho b\u1ec7nh nh\u00e2n.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#What_Is_Otezla\" >Otezla l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#What_Is_Otezla_Used_For\" >Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#How_Is_Otezla_Used\" >Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#How_Does_It_Work\" >N\u00f3 ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Drug_Dosage\" >Li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Precautions\" >C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/#Cost\" >Tr\u1ecb gi\u00e1<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Otezla\"><\/span>Otezla l\u00e0 g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla l\u00e0 thu\u1ed1c theo toa \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng b\u00e1m, vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn v\u00e0 lo\u00e9t mi\u1ec7ng li\u00ean quan \u0111\u1ebfn b\u1ec7nh Beh\u00e7et.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c n\u00e0y thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf phosphodiesterase-4 (PDE4) v\u00e0 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf t\u00ecnh tr\u1ea1ng vi\u00eam trong c\u01a1 th\u1ec3. Otezla l\u00e0 t\u00ean th\u01b0\u01a1ng hi\u1ec7u c\u1ee7a <\/span><a href=\"https:\/\/www.healthline.com\/health\/drugs\/generic-vs-brand#generic-drugs\"><span style=\"font-weight: 400;\">thu\u1ed1c g\u1ed1c<\/span><\/a><span style=\"font-weight: 400;\">, l\u1eddi m\u1edf \u0111\u1ea7u.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">K\u1ec3 t\u1eeb khi n\u00f3 <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4665061\/\"><span style=\"font-weight: 400;\">ph\u00ea duy\u1ec7t n\u0103m 2014<\/span><\/a><span style=\"font-weight: 400;\">, Otezla \u0111\u00e3 tr\u1edf n\u00ean ph\u1ed5 bi\u1ebfn trong s\u1ed1 b\u1ec7nh nh\u00e2n v\u00e0 c\u00e1c chuy\u00ean gia ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe nh\u01b0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 cho b\u1ec7nh vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn, m\u1ecdi giai \u0111o\u1ea1n c\u1ee7a b\u1ec7nh v\u1ea3y n\u1ebfn m\u1ea3ng b\u00e1m v\u00e0 lo\u00e9t mi\u1ec7ng li\u00ean quan \u0111\u1ebfn b\u1ec7nh Beh\u00e7et.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ed9t trong nh\u1eefng l\u1ee3i th\u1ebf ch\u00ednh c\u1ee7a Otezla l\u00e0 n\u00f3 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00f4ng sinh h\u1ecdc, ngh\u0129a l\u00e0 n\u00f3 kh\u00f4ng ch\u1ee9a t\u1ebf b\u00e0o s\u1ed1ng ho\u1eb7c protein. \u0110i\u1ec1u n\u00e0y l\u00e0m cho n\u00f3 tr\u1edf th\u00e0nh m\u1ed9t l\u1ef1a ch\u1ecdn an to\u00e0n h\u01a1n cho nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p \u0111\u01b0\u1ee3c thu\u1ed1c sinh h\u1ecdc ho\u1eb7c c\u00f3 nguy c\u01a1 nhi\u1ec5m tr\u00f9ng cao h\u01a1n.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c sinh h\u1ecdc l\u00e0 thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c l\u00e0m t\u1eeb t\u1ebf b\u00e0o s\u1ed1ng ho\u1eb7c protein v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb cho nh\u1eefng ng\u01b0\u1eddi b\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn v\u00e0 vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn. Tuy nhi\u00ean, thu\u1ed1c sinh h\u1ecdc c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m tr\u00f9ng, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 h\u1ec7 mi\u1ec5n d\u1ecbch suy y\u1ebfu.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">H\u00e3y nh\u1edb r\u1eb1ng Otezla kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi t\u1ea5t c\u1ea3 m\u1ecdi ng\u01b0\u1eddi.<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed tr\u1ea7m c\u1ea3m, c\u00f3 \u00fd \u0111\u1ecbnh ho\u1eb7c h\u00e0nh vi t\u1ef1 t\u1eed v\u00ec c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam c\u00e1c tri\u1ec7u ch\u1ee9ng.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Thu\u1ed1c n\u00e0y c\u0169ng c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c nh\u01b0 rifampin, St. John&#039;s Wort v\u00e0 carbamazepine, v\u00e0 kh\u00f4ng n\u00ean d\u00f9ng chung v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Do \u0111\u00f3, b\u1ea1n n\u00ean lu\u00f4n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 ti\u1ec1n s\u1eed s\u1ee9c kh\u1ecfe c\u1ee7a m\u00ecnh v\u00e0 b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c n\u00e0o b\u1ea1n \u0111ang d\u00f9ng.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Otezla_Used_For\"><\/span>Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u0111\u01b0\u1ee3c C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>B\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng b\u00e1m<\/b><span style=\"font-weight: 400;\">:Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng b\u00e1m \u1edf m\u1ee9c \u0111\u1ed9 trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng \u1edf ng\u01b0\u1eddi l\u1edbn, nh\u1eefng ng\u01b0\u1eddi c\u1ea7n \u0111i\u1ec1u tr\u1ecb to\u00e0n th\u00e2n ho\u1eb7c li\u1ec7u ph\u00e1p quang tr\u1ecb li\u1ec7u.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn:<\/b><span style=\"font-weight: 400;\"> Otezla \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn ho\u1ea1t \u0111\u1ed9ng \u1edf ng\u01b0\u1eddi l\u1edbn, c\u00f3 th\u1ec3 d\u00f9ng \u0111\u01a1n l\u1ebb ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/span><\/li>\n\n\n\n<li><b>Lo\u00e9t mi\u1ec7ng li\u00ean quan \u0111\u1ebfn b\u1ec7nh Beh\u00e7et:<\/b><span style=\"font-weight: 400;\"> Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb lo\u00e9t mi\u1ec7ng li\u00ean quan \u0111\u1ebfn <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12980-behcets-disease\">B\u1ec7nh Beh\u00e7et<\/a> \u1edf ng\u01b0\u1eddi l\u1edbn.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Otezla_Used\"><\/span>Otezla \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n. B\u1ea1n n\u00ean nu\u1ed1t vi\u00ean thu\u1ed1c v\u1edbi n\u01b0\u1edbc m\u00e0 kh\u00f4ng nghi\u1ec1n n\u00e1t, nhai ho\u1eb7c b\u1ebb vi\u00ean thu\u1ed1c.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i tu\u00e2n theo h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129 khi d\u00f9ng thu\u1ed1c n\u00e0y v\u00e0 kh\u00f4ng thay \u0111\u1ed5i li\u1ec1u l\u01b0\u1ee3ng ho\u1eb7c ng\u1eebng d\u00f9ng thu\u1ed1c m\u00e0 kh\u00f4ng tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc. C\u00f3 th\u1ec3 m\u1ea5t v\u00e0i tu\u1ea7n \u0111\u1ec3 Otezla b\u1eaft \u0111\u1ea7u c\u00f3 t\u00e1c d\u1ee5ng v\u00e0 n\u00ean d\u00f9ng li\u00ean t\u1ee5c \u0111\u1ec3 duy tr\u00ec t\u00e1c d\u1ee5ng.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n qu\u00ean m\u1ed9t li\u1ec1u, b\u1ea1n n\u00ean u\u1ed1ng ngay khi nh\u1edb ra, tr\u1eeb khi g\u1ea7n \u0111\u1ebfn gi\u1edd u\u1ed1ng li\u1ec1u ti\u1ebfp theo, trong tr\u01b0\u1eddng h\u1ee3p \u0111\u00f3, b\u1ea1n n\u00ean b\u1ecf qua li\u1ec1u \u0111\u00e3 qu\u00ean v\u00e0 ti\u1ebfp t\u1ee5c l\u1ecbch d\u00f9ng thu\u1ed1c th\u00f4ng th\u01b0\u1eddng.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_It_Work\"><\/span>N\u00f3 ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">T\u00ecnh tr\u1ea1ng vi\u00eam x\u1ea3y ra khi h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch ph\u1ea3n \u1ee9ng qu\u00e1 m\u1ee9c v\u00e0 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u t\u1ebf b\u00e0o v\u00e0 protein g\u00e2y vi\u00eam. PDE4 l\u00e0 m\u1ed9t lo\u1ea1i enzyme ph\u00e2n h\u1ee7y m\u1ed9t ph\u00e2n t\u1eed \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cyclic_adenosine_monophosphate\">adenosine monophosphate v\u00f2ng<\/a> (cAMP), ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng vi\u00eam trong c\u01a1 th\u1ec3. PDE4 l\u01b0u th\u00f4ng trong c\u01a1 th\u1ec3 c\u00e0ng nhi\u1ec1u th\u00ec c\u00e0ng ph\u00e1 v\u1ee1 cAMP, d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng vi\u00eam t\u0103ng l\u00ean.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf PDE4, Otezla l\u00e0m t\u0103ng m\u1ee9c cAMP, gi\u1ea3m s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o v\u00e0 protein g\u00e2y vi\u00eam. \u0110i\u1ec1u n\u00e0y gi\u00fap ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng vi\u00eam v\u00e0 gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au kh\u1edbp, s\u01b0ng v\u00e0 vi\u00eam da.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110i\u1ec1u quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd l\u00e0 Otezla kh\u00f4ng ph\u1ea3i l\u00e0 thu\u1ed1c ch\u1eefa kh\u1ecfi t\u00ecnh tr\u1ea1ng vi\u00eam nhi\u1ec5m, nh\u01b0ng c\u00f3 th\u1ec3 gi\u00fap ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng n\u00e0y.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects.jpg\" alt=\"Woman suffering from Otezal side effects\" class=\"wp-image-22940\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/otezla-side-effects-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">Gi\u1ed1ng nh\u01b0 t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i thu\u1ed1c, Otezla c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5. Sau \u0111\u00e2y l\u00e0 m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Bu\u1ed3n n\u00f4n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ti\u00eau ch\u1ea3y<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u do c\u0103ng th\u1eb3ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Gi\u1ea3m c\u00e2n<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Tr\u1ea7m c\u1ea3m<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Suy ngh\u0129 ho\u1eb7c h\u00e0nh vi t\u1ef1 t\u1eed<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tr\u1ea7m c\u1ea3m ho\u1eb7c lo \u00e2u ng\u00e0y c\u00e0ng tr\u1ea7m tr\u1ecdng h\u01a1n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ph\u00f9 m\u1ea1ch (s\u01b0ng m\u00f4i, l\u01b0\u1ee1i ho\u1eb7c m\u1eb7t)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ti\u00eau ch\u1ea3y n\u1eb7ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">N\u00f4n d\u1eef d\u1ed9i<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n g\u1eb7p b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o trong s\u1ed1 n\u00e0y ho\u1eb7c b\u1ea5t k\u1ef3 tri\u1ec7u ch\u1ee9ng b\u1ea5t th\u01b0\u1eddng n\u00e0o kh\u00e1c sau khi d\u00f9ng Otezla, \u0111\u1eebng ng\u1ea7n ng\u1ea1i li\u00ean h\u1ec7 ngay v\u1edbi nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ea1n. Nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ea1n c\u00f3 th\u1ec3 gi\u00fap x\u00e1c \u0111\u1ecbnh ph\u01b0\u01a1ng \u00e1n h\u00e0nh \u0111\u1ed9ng t\u1ed1t nh\u1ea5t \u0111\u1ec3 ki\u1ec3m so\u00e1t b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o b\u1ea1n c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Drug_Dosage\"><\/span>Li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Otezla n\u00ean \u0111\u01b0\u1ee3c chu\u1ea9n \u0111\u1ed9 \u0111\u1ebfn li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 30 mg hai l\u1ea7n m\u1ed7i ng\u00e0y. M\u1ed9t l\u1ecbch tr\u00ecnh chu\u1ea9n \u0111\u1ed9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 gi\u1ea3m kh\u1ea3 n\u0103ng x\u1ea3y ra c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (GI). L\u1ecbch tr\u00ecnh nh\u01b0 sau:&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y 1: 10 mg v\u00e0o bu\u1ed5i s\u00e1ng<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y 2: 10 mg v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 10 mg v\u00e0o bu\u1ed5i t\u1ed1i<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y 3: 10 mg v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 20 mg v\u00e0o bu\u1ed5i t\u1ed1i<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y 4: 20 mg v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 20 mg v\u00e0o bu\u1ed5i t\u1ed1i<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y 5: 20 mg v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 30 mg v\u00e0o bu\u1ed5i t\u1ed1i<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ng\u00e0y th\u1ee9 6 v\u00e0 ti\u1ebfp theo: 30 mg v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 30 mg v\u00e0o bu\u1ed5i t\u1ed1i<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe c\u00f3 th\u1ec3 thay \u0111\u1ed5i li\u1ec1u thu\u1ed1c c\u1ee7a b\u1ea1n n\u1ebfu b\u1ea1n b\u1ecb t\u1ed5n th\u01b0\u01a1ng th\u1eadn nghi\u00eam tr\u1ecdng.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions\"><\/span>C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">C\u00f3 m\u1ed9t s\u1ed1 bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba b\u1ea1n n\u00ean th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc v\u00e0 sau khi s\u1eed d\u1ee5ng Otezla.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng thu\u1ed1c:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">H\u00e3y cho b\u00e1c s\u0129 bi\u1ebft n\u1ebfu b\u1ea1n b\u1ecb d\u1ecb \u1ee9ng, m\u1eafc b\u1ec7nh l\u00fd n\u00e0o \u0111\u00f3 ho\u1eb7c \u0111ang d\u00f9ng thu\u1ed1c kh\u00e1c.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">H\u00e3y cho b\u00e1c s\u0129 bi\u1ebft n\u1ebfu b\u1ea1n \u0111ang mang thai ho\u1eb7c c\u00f3 k\u1ebf ho\u1ea1ch mang thai v\u00ec Otezla c\u00f3 th\u1ec3 kh\u00f4ng an to\u00e0n trong th\u1eddi k\u1ef3 mang thai.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">H\u00e3y th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 n\u1ebfu b\u1ea1n c\u00f3 ti\u1ec1n s\u1eed tr\u1ea7m c\u1ea3m ho\u1eb7c c\u00f3 \u00fd \u0111\u1ecbnh t\u1ef1 t\u1eed, v\u00ec Otezla c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 tr\u1ea7m c\u1ea3m ho\u1eb7c h\u00e0nh vi t\u1ef1 t\u1eed.<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Sau khi s\u1eed d\u1ee5ng thu\u1ed1c:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Th\u1ef1c hi\u1ec7n theo h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129 v\u1ec1 li\u1ec1u l\u01b0\u1ee3ng v\u00e0 t\u1ea7n su\u1ea5t s\u1eed d\u1ee5ng.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Theo d\u00f5i m\u1ecdi t\u00e1c d\u1ee5ng ph\u1ee5 m\u00e0 b\u1ea1n c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i v\u00e0 b\u00e1o cho b\u00e1c s\u0129.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tr\u00e1nh u\u1ed1ng r\u01b0\u1ee3u khi d\u00f9ng Otezla v\u00ec c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng gan.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ch\u1ec9 ng\u1eebng d\u00f9ng Otezla sau khi tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129, v\u00ec vi\u1ec7c ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng t\u00e1i ph\u00e1t.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">B\u1ea3o qu\u1ea3n Otezla \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng v\u00e0 tr\u00e1nh \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>Tr\u1ecb gi\u00e1<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Chi ph\u00ed c\u1ee7a Otezla c\u00f3 th\u1ec3 thay \u0111\u1ed5i t\u00f9y thu\u1ed9c v\u00e0o m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1, ch\u1eb3ng h\u1ea1n nh\u01b0 qu\u1ed1c gia c\u1ee7a b\u1ea1n, ph\u1ea1m vi b\u1ea3o hi\u1ec3m v\u00e0 li\u1ec1u d\u00f9ng.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">T\u1ea1i Hoa K\u1ef3, gi\u00e1 b\u00e1n bu\u00f4n trung b\u00ecnh (AWP) c\u1ee7a Otezla l\u00e0 kho\u1ea3ng $153 cho m\u1ed9t vi\u00ean thu\u1ed1c, v\u1edbi li\u1ec1u l\u01b0\u1ee3ng khuy\u1ebfn c\u00e1o l\u00e0 hai vi\u00ean m\u1ed7i ng\u00e0y. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 chi ph\u00ed c\u00f3 th\u1ec3 v\u00e0o kho\u1ea3ng $4.600 cho m\u1ed9t li\u1ec1u d\u00f9ng 60 vi\u00ean thu\u1ed1c, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi m\u1ed9t li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb trong m\u1ed9t th\u00e1ng.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110i\u1ec1u quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd l\u00e0 m\u1ee9c gi\u00e1 n\u00e0y ch\u1ec9 l\u00e0 \u01b0\u1edbc t\u00ednh v\u00e0 c\u00f3 th\u1ec3 kh\u00f4ng ph\u1ea3n \u00e1nh chi ph\u00ed th\u1ef1c t\u1ebf m\u00e0 b\u1ec7nh nh\u00e2n ph\u1ea3i tr\u1ea3 cho Otezla. B\u1ec7nh nh\u00e2n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe ho\u1eb7c d\u01b0\u1ee3c s\u0129 \u0111\u1ec3 bi\u1ebft th\u00f4ng tin gi\u00e1 ch\u00ednh x\u00e1c v\u00e0 c\u1eadp nh\u1eadt h\u01a1n.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ngo\u00e0i ra, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3m gi\u00e1 ho\u1eb7c \u0111\u0103ng k\u00fd <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/financial-assistance\/\">ch\u01b0\u01a1ng tr\u00ecnh h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh<\/a> \u0111\u1ec3 gi\u00fap b\u00f9 \u0111\u1eafp chi ph\u00ed.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng, c\u00e1c li\u1ec7u ph\u00e1p t\u1ea1i ch\u1ed7 nh\u01b0 kem ho\u1eb7c thu\u1ed1c m\u1ee1 \u0111\u00f4i khi kh\u00f4ng \u0111\u1ee7. B\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh su\u1ed1t \u0111\u1eddi, bao g\u1ed3m c\u00e1c chu k\u1ef3 b\u00f9ng ph\u00e1t v\u00e0 thuy\u00ean gi\u1ea3m. Nhi\u1ec1u b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh v\u1ea9y n\u1ebfn m\u1ea3ng c\u0169ng c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n th\u00e0nh vi\u00eam kh\u1edbp v\u1ea9y n\u1ebfn, g\u00e2y \u0111au, s\u01b0ng v\u00e0 vi\u00eam xung quanh kh\u1edbp.\u00a0<\/p>","protected":false},"author":27,"featured_media":22939,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[33],"class_list":["post-22936","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-dr-samantha-kaeberlein"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Otezla: An Effective Non-Biologic Option for Treating Plaque Psoriasis and Psoriatic Arthritis<\/title>\n<meta name=\"description\" content=\"Learn about Otezla and how it treats plaque psoriasis and psoriatic arthritis. Topics include how the drug works, dosage, and side effects.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Otezla: An Effective Non-Biologic Option for Treating Plaque Psoriasis and Psoriatic Arthritis\" \/>\n<meta property=\"og:description\" content=\"Learn about Otezla and how it treats plaque psoriasis and psoriatic arthritis. Topics include how the drug works, dosage, and side effects.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\/\" \/>\n<meta property=\"og:site_name\" content=\"AmeriPharma\u00ae Specialty Care\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ameripharma\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-23T19:40:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-19T21:45:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"853\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Dr. Samantha Kaeberlein, PharmD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dr. Samantha Kaeberlein, PharmD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 ph\u00fat\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/\"},\"author\":{\"name\":\"Dr. Samantha Kaeberlein, PharmD\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/es\\\/#\\\/schema\\\/person\\\/aa941bb470287e10309b2fe7f5b15430\"},\"headline\":\"Otezla: An Effective Non-Biologic Option for Treating Plaque Psoriasis and Psoriatic Arthritis\",\"datePublished\":\"2023-06-23T19:40:04+00:00\",\"dateModified\":\"2026-03-19T21:45:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/\"},\"wordCount\":1189,\"publisher\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/es\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2023\\\/06\\\/psoriatic-arthritis.jpg\",\"keywords\":[\"Dr. Samantha Kaeberlein\"],\"articleSection\":[\"Discontinued\"],\"inLanguage\":\"vi\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/\",\"name\":\"Otezla: An Effective Non-Biologic Option for Treating Plaque Psoriasis and Psoriatic Arthritis\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/es\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/discontinued\\\/otezla-an-effective-non-biologic-option-for-treating-plaque-psoriasis-and-psoriatic-arthritis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2023\\\/06\\\/psoriatic-arthritis.jpg\",\"datePublished\":\"2023-06-23T19:40:04+00:00\",\"dateModified\":\"2026-03-19T21:45:21+00:00\",\"description\":\"Learn about Otezla and how it treats plaque psoriasis and psoriatic arthritis. 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Many patients who have plaque psoriasis can also go on to develop psoriatic arthritis, which causes pain, swelling, and inflammation around the joints.\u00a0","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-300x200.jpg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",600,400,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/06\/psoriatic-arthritis.jpg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Samantha Kaeberlein, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/samantha\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/discontinued\/\" rel=\"category tag\">Discontinued<\/a>","rttpg_excerpt":"For patients with plaque psoriasis, topical therapies such as creams or ointments sometimes are not enough. Plaque psoriasis is a lifelong illness, consisting of cycles with flare-ups and remission. Many patients who have plaque psoriasis can also go on to develop psoriatic arthritis, which causes pain, swelling, and inflammation around the joints.\u00a0","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/22936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/comments?post=22936"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/22936\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media\/22939"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media?parent=22936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/categories?post=22936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/tags?post=22936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}