{"id":22407,"date":"2023-03-14T11:15:11","date_gmt":"2023-03-14T18:15:11","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=22407"},"modified":"2026-03-19T14:53:28","modified_gmt":"2026-03-19T21:53:28","slug":"what-is-stivarga-regorafenib","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/","title":{"rendered":"Stivarga (Regorafenib) l\u00e0 g\u00ec?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Stivarga (t\u00ean chung: regorafenib) l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 l\u00e2y lan c\u1ee7a c\u00e1c t\u1ebf b\u00e0o \u00e1c t\u00ednh trong c\u01a1 th\u1ec3. Kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 kh\u00e1c, Stivarga \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u lo\u1ea1i ung th\u01b0 kh\u00e1c nhau, bao g\u1ed3m ung th\u01b0 gan, ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng v\u00e0 m\u1ed9t lo\u1ea1i kh\u1ed1i u hi\u1ebfm g\u1eb7p \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ru\u1ed9t, th\u1ef1c qu\u1ea3n v\u00e0 d\u1ea1 d\u00e0y \u1edf ng\u01b0\u1eddi. M\u1eb7c d\u00f9 hi\u1ec7u qu\u1ea3 ch\u1ed1ng l\u1ea1i nhi\u1ec1u lo\u1ea1i ung th\u01b0, thu\u1ed1c n\u00e0y ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng sau khi t\u1ea5t c\u1ea3 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb thay th\u1ebf kh\u00e1c \u0111\u00e3 th\u1ea5t b\u1ea1i.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#What_Is_Stivarga_Used_To_Treat\" >Thu\u1ed1c Stivarga \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Colorectal_Cancer\" >Ung th\u01b0 \u0111\u1ea1i tr\u00e0ng<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Hepatocellular_Carcinoma\" >Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Gastrointestinal_Stromal_Tumor_GIST\" >U m\u00f4 \u0111\u1ec7m \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (GIST)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#How_Does_It_Work\" >N\u00f3 ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Effectiveness_and_Approval\" >Hi\u1ec7u qu\u1ea3 v\u00e0 s\u1ef1 ch\u1ea5p thu\u1eadn<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Drug_Administration_and_Dosage\" >Qu\u1ea3n l\u00fd thu\u1ed1c v\u00e0 li\u1ec1u d\u00f9ng<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Precautions_When_Taking_Stivarga\" >Th\u1eadn tr\u1ecdng khi d\u00f9ng Stivarga<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Stivarga_Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Stivarga<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-stivarga-regorafenib\/#Cost\" >Tr\u1ecb gi\u00e1<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\" id=\"h-what-is-stivarga-used-to-treat\"><span class=\"ez-toc-section\" id=\"What_Is_Stivarga_Used_To_Treat\"><\/span>Thu\u1ed1c Stivarga \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">C\u00f3 ba lo\u1ea1i ung th\u01b0 ch\u00ednh c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Stivarga:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-colorectal-cancer\"><span class=\"ez-toc-section\" id=\"Colorectal_Cancer\"><\/span>Ung th\u01b0 \u0111\u1ea1i tr\u00e0ng<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ung th\u01b0 ru\u1ed9t v\u00e0 tr\u1ef1c tr\u00e0ng. Stivarga l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng hi\u1ec7u qu\u1ea3, \u0111\u1eb7c bi\u1ec7t khi b\u1ec7nh \u0111\u00e3 ti\u1ebfn tri\u1ec3n sang c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3. Tuy nhi\u00ean, tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng Stivarga, b\u1ec7nh nh\u00e2n ph\u1ea3i tr\u1ea3i qua c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0: <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/cancer\/copiktra-duvelisib\/\">h\u00f3a tr\u1ecb<\/a> d\u1ef1a tr\u00ean c\u00e1c lo\u1ea1i thu\u1ed1c nh\u01b0 fluoropyrimidine, c\u0169ng nh\u01b0 li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1ng VEGF v\u00e0 kh\u00e1ng EGFR.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-hepatocellular-carcinoma\"><span class=\"ez-toc-section\" id=\"Hepatocellular_Carcinoma\"><\/span>Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan (HCC) l\u00e0 m\u1ed9t lo\u1ea1i ung th\u01b0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn gan. B\u1ec7nh nh\u00e2n n\u00ean th\u1eed sorafenib tr\u01b0\u1edbc khi l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Stivarga.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-gastrointestinal-stromal-tumor-gist\"><span class=\"ez-toc-section\" id=\"Gastrointestinal_Stromal_Tumor_GIST\"><\/span>U m\u00f4 \u0111\u1ec7m \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (GIST)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.cancer.org\/cancer\/gastrointestinal-stromal-tumor.html\">GIST<\/a> l\u00e0 lo\u1ea1i ung th\u01b0 hi\u1ebfm g\u1eb7p, th\u01b0\u1eddng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u1ea1 d\u00e0y, ru\u1ed9t v\u00e0 h\u1ecdng. Stivarga l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb cho GIST khi kh\u00f4ng th\u1ec3 ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf ho\u1eb7c \u0111\u00e3 di c\u0103n sang c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3. Tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng Stivarga, b\u1ec7nh nh\u00e2n ph\u1ea3i \u0111\u00e3 th\u1eed \u0111i\u1ec1u tr\u1ecb b\u1eb1ng sunitinib v\u00e0 imatinib.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-how-does-it-work\"><span class=\"ez-toc-section\" id=\"How_Does_It_Work\"><\/span>N\u00f3 ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Stivarga ho\u1ea1t \u0111\u1ed9ng th\u00f4ng qua t\u00e1c d\u1ee5ng c\u1ee7a ho\u1ea1t ch\u1ea5t regorafenib. Regorafenib l\u00e0 m\u1ed9t <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31643906\/\">ch\u1ea5t \u1ee9c ch\u1ebf protein kinase<\/a> c\u00f3 ngh\u0129a l\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a n\u00f3 l\u00e0 ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c enzyme ch\u1ecbu tr\u00e1ch nhi\u1ec7m ph\u00e1t tri\u1ec3n ngu\u1ed3n cung c\u1ea5p m\u00e1u cho kh\u1ed1i u.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Khi c\u00e1c enzyme n\u00e0y b\u1ecb \u1ee9c ch\u1ebf v\u00e0 ngu\u1ed3n cung c\u1ea5p m\u00e1u cho kh\u1ed1i u b\u1ecb gi\u00e1n \u0111o\u1ea1n, s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 s\u1ebd b\u1ecb \u1ee9c ch\u1ebf v\u00e0 ch\u00fang b\u1eaft \u0111\u1ea7u ph\u00e2n h\u1ee7y. Nh\u1edd \u0111\u00f3, s\u1ef1 t\u0103ng tr\u01b0\u1edfng, ph\u00e1t tri\u1ec3n v\u00e0 lan r\u1ed9ng c\u1ee7a ch\u00fang b\u1ecb d\u1eebng l\u1ea1i, v\u00e0 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u c\u1ea3m th\u1ea5y d\u1ec5 ch\u1ecbu h\u01a1n.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-effectiveness-and-approval\"><span class=\"ez-toc-section\" id=\"Effectiveness_and_Approval\"><\/span>Hi\u1ec7u qu\u1ea3 v\u00e0 s\u1ef1 ch\u1ea5p thu\u1eadn<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-expands-approved-use-stivarga-treat-liver-cancer\"><span style=\"font-weight: 400;\">C\u00e1c c\u01a1 quan c\u00f3 th\u1ea9m quy\u1ec1n<\/span><\/a><span style=\"font-weight: 400;\"> \u0111\u00e3 ph\u00ea duy\u1ec7t s\u1eed d\u1ee5ng Stivarga \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c nhau d\u1ef1a tr\u00ean k\u1ebft qu\u1ea3 c\u1ee7a c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u00e0 nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh \u0111\u1ec3 ki\u1ec3m tra hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110\u1ed1i v\u1edbi ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean 760 ng\u01b0\u1eddi tham gia kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u ph\u1ee5c h\u1ed3i sau c\u00e1c li\u1ec7u ph\u00e1p tr\u01b0\u1edbc \u0111\u00f3. Nghi\u00ean c\u1ee9u n\u00e0y ph\u00e1t hi\u1ec7n ra r\u1eb1ng nh\u1eefng ng\u01b0\u1eddi s\u1eed d\u1ee5ng Stivarga s\u1ed1ng l\u00e2u h\u01a1n (trung b\u00ecnh 6,4 th\u00e1ng) so v\u1edbi nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng s\u1eed d\u1ee5ng Stivarga.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110\u1ed1i v\u1edbi GIST, 199 b\u1ec7nh nh\u00e2n \u0111\u00e3 tham gia th\u1eed nghi\u1ec7m, cho th\u1ea5y nh\u1eefng b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng Stivarga s\u1ed1ng l\u00e2u h\u01a1n m\u00e0 kh\u00f4ng l\u00e0m t\u00ecnh tr\u1ea1ng b\u1ec7nh tr\u1edf n\u00ean tr\u1ea7m tr\u1ecdng h\u01a1n. Trung b\u00ecnh, nh\u1eefng b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng Stivarga \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb GIST s\u1ed1ng \u0111\u01b0\u1ee3c 4,8 th\u00e1ng, trong khi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng d\u00f9ng thu\u1ed1c ch\u1ec9 s\u1ed1ng \u0111\u01b0\u1ee3c 0,9 th\u00e1ng.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Cu\u1ed1i c\u00f9ng, 573 b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a Stivarga trong \u0111i\u1ec1u tr\u1ecb HCC, v\u00e0 k\u1ebft qu\u1ea3 cho th\u1ea5y kh\u1ea3 n\u0103ng s\u1ed1ng l\u00e2u h\u01a1n khi s\u1eed d\u1ee5ng Stivarga \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb HCC so v\u1edbi khi kh\u00f4ng s\u1eed d\u1ee5ng. Trong th\u1eed nghi\u1ec7m, nh\u1eefng b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng Stivarga s\u1ed1ng \u0111\u01b0\u1ee3c 10,6 th\u00e1ng, trong khi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng s\u1eed d\u1ee5ng ch\u1ec9 s\u1ed1ng \u0111\u01b0\u1ee3c 7,8 th\u00e1ng.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-administration-and-dosage\"><span class=\"ez-toc-section\" id=\"Drug_Administration_and_Dosage\"><\/span>Qu\u1ea3n l\u00fd thu\u1ed1c v\u00e0 li\u1ec1u d\u00f9ng<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ed9t b\u00e1c s\u0129 c\u00f3 \u0111\u1ee7 kinh nghi\u1ec7m \u0111i\u1ec1u tr\u1ecb ung th\u01b0, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c lo\u1ea1i ung th\u01b0 \u0111\u00e3 \u0111\u1ec1 c\u1eadp \u1edf tr\u00ean, n\u00ean gi\u00e1m s\u00e1t vi\u1ec7c s\u1eed d\u1ee5ng Stivarga. C\u00e1ch duy nh\u1ea5t \u0111\u1ec3 mua thu\u1ed1c l\u00e0 ph\u1ea3i c\u00f3 \u0111\u01a1n thu\u1ed1c.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">D\u1ea1ng thu\u1ed1c ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a Stivarga l\u00e0 vi\u00ean n\u00e9n. M\u1ed7i vi\u00ean n\u00e9n c\u00f3 h\u00e0m l\u01b0\u1ee3ng 40 mg v\u00e0 \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ed9t li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb 4 tu\u1ea7n.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u khuy\u1ebfn c\u00e1o \u0111\u1ea7u ti\u00ean l\u00e0 160 mg: b\u1ed1n vi\u00ean 40 mg, u\u1ed1ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y trong ba tu\u1ea7n. Sau \u0111\u00f3, ng\u1eebng thu\u1ed1c trong m\u1ed9t tu\u1ea7n. Thu\u1ed1c \u0111\u01b0\u1ee3c u\u1ed1ng h\u00e0ng ng\u00e0y v\u1edbi m\u1ed9t b\u1eefa \u0103n nh\u1eb9, \u00edt ch\u1ea5t b\u00e9o, \u00edt calo, c\u00f9ng v\u1edbi n\u01b0\u1edbc.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n qu\u00ean m\u1ed9t li\u1ec1u, h\u00e3y u\u1ed1ng ngay khi nh\u1edb ra. Tuy nhi\u00ean, n\u1ebfu g\u1ea7n \u0111\u1ebfn gi\u1edd u\u1ed1ng li\u1ec1u ti\u1ebfp theo, h\u00e3y h\u1ee7y li\u1ec1u \u0111\u00e3 qu\u00ean v\u00e0 ch\u1ec9 u\u1ed1ng li\u1ec1u ti\u1ebfp theo. Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng \u0111\u01b0\u1ee3c u\u1ed1ng hai li\u1ec1u c\u00f9ng m\u1ed9t l\u00fac. N\u1ebfu b\u1ecb qu\u00e1 li\u1ec1u, h\u00e3y li\u00ean h\u1ec7 ngay v\u1edbi b\u00e1c s\u0129 ho\u1eb7c c\u01a1 s\u1edf y t\u1ebf.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-precautions-when-taking-stivarga\"><span class=\"ez-toc-section\" id=\"Precautions_When_Taking_Stivarga\"><\/span>Th\u1eadn tr\u1ecdng khi d\u00f9ng Stivarga<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"299\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient.jpg\" alt=\"Patient receiving Stivarga treatment for metastatic colorectal cancer.\" class=\"wp-image-22409\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient-300x214.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient-86x61.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient-167x119.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient-280x199.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga-patient-370x263.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho \u0111\u1ebfn khi b\u1ec7nh nh\u00e2n ti\u1ebfp t\u1ee5c nh\u1eadn \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c cho \u0111\u1ebfn khi c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u1edf n\u00ean qu\u00e1 nghi\u00eam tr\u1ecdng. C\u00f3 th\u1ec3 gi\u1ea3m li\u1ec1u ho\u1eb7c ng\u1eebng h\u1eb3n n\u1ebfu m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 b\u1eaft \u0111\u1ea7u xu\u1ea5t hi\u1ec7n. Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, c\u1ea7n ki\u1ec3m tra ch\u1ee9c n\u0103ng gan v\u00e0 huy\u1ebft \u00e1p th\u01b0\u1eddng xuy\u00ean.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Stivarga c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh l\u00e0nh v\u1ebft th\u01b0\u01a1ng, bao g\u1ed3m c\u1ea3 v\u1ebft m\u1ed5. H\u00e3y th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129 n\u1ebfu b\u1ea1n c\u1ea7n ph\u1eabu thu\u1eadt. Ngo\u00e0i ra, h\u00e3y ng\u1eebng d\u00f9ng thu\u1ed1c hai tu\u1ea7n tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ho\u1ea1t ch\u1ea5t regorafenib c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi b\u01b0\u1edfi, g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng; do \u0111\u00f3, tr\u00e1nh \u0103n b\u01b0\u1edfi ho\u1eb7c n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi khi \u0111ang d\u00f9ng thu\u1ed1c n\u00e0y. Ngo\u00e0i ra, tr\u00e1nh s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng c\u00f3 ch\u1ee9a: <a href=\"https:\/\/www.nccih.nih.gov\/health\/st-johns-wort\">C\u00e2y ban \u00c2u<\/a>.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Cu\u1ed1i c\u00f9ng, b\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf n\u01a1i s\u1ea1ch s\u1ebd, tr\u00e1nh \u1ea9m v\u00e0 nhi\u1ec7t, v\u00e0 \u0111\u1ea3m b\u1ea3o thu\u1ed1c v\u1eabn c\u00f2n trong bao b\u00ec g\u1ed1c. N\u1ebfu ph\u1ea3i thay thu\u1ed1c, h\u00e3y \u0111\u1ea3m b\u1ea3o thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u1ef1ng trong h\u1ed9p c\u00f3 ch\u1ea5t b\u1ea3o qu\u1ea3n h\u00fat \u1ea9m. V\u1ee9t b\u1ecf ph\u1ea7n Stivarga ch\u01b0a s\u1eed d\u1ee5ng sau b\u1ea3y tu\u1ea7n k\u1ec3 t\u1eeb khi m\u1edf l\u1ecd.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-stivarga-side-effects\"><span class=\"ez-toc-section\" id=\"Stivarga_Side_Effects\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Stivarga<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 m\u00e0 b\u1ea1n c\u00f3 th\u1ec3 l\u01b0u \u00fd khi s\u1eed d\u1ee5ng Stivarga bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u v\u00e0 thay \u0111\u1ed5i tr\u1ea1ng th\u00e1i tinh th\u1ea7n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">D\u1ea5u hi\u1ec7u nhi\u1ec5m tr\u00f9ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u0103ng huy\u1ebft \u00e1p<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110\u1ee5c l\u1ed7<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ph\u1ea3n \u1ee9ng da tay ch\u00e2n v\u00e0 ph\u00e1t ban da nghi\u00eam tr\u1ecdng&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 gan nh\u01b0 v\u00e0ng da ho\u1eb7c n\u01b0\u1edbc ti\u1ec3u s\u1eabm m\u00e0u nh\u01b0 n\u01b0\u1edbc tr\u00e0&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 ch\u1eefa l\u00e0nh v\u1ebft th\u01b0\u01a1ng&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n n\u00ean \u0111i kh\u00e1m b\u00e1c s\u0129 ngay l\u1eadp t\u1ee9c n\u1ebfu nh\u1eadn th\u1ea5y b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o sau \u0111\u00e2y.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-cost\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>Tr\u1ecb gi\u00e1<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Chi ph\u00ed mua s\u1ec9 cho m\u1ed9t vi\u00ean Stivarga 40 mg l\u00e0 $21.546 cho 84 vi\u00ean. \u0110\u00e2y ch\u1ec9 l\u00e0 \u01b0\u1edbc t\u00ednh v\u00ec m\u1ed9t s\u1ed1 bi\u1ebfn s\u1ed1, bao g\u1ed3m \u0111\u1ecba \u0111i\u1ec3m, b\u1ea3o hi\u1ec3m, ch\u01b0\u01a1ng tr\u00ecnh ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u00e0 nh\u00e0 thu\u1ed1c, s\u1ebd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chi ph\u00ed th\u1ef1c t\u1ebf c\u1ee7a thu\u1ed1c.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Stivarga (t\u00ean chung: regorafenib) l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 l\u00e2y lan c\u1ee7a c\u00e1c t\u1ebf b\u00e0o \u00e1c t\u00ednh trong c\u01a1 th\u1ec3. Kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 kh\u00e1c, Stivarga \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u lo\u1ea1i ung th\u01b0 kh\u00e1c nhau, bao g\u1ed3m ung th\u01b0 gan, ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng v\u00e0 m\u1ed9t lo\u1ea1i kh\u1ed1i u hi\u1ebfm g\u1eb7p \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ru\u1ed9t, th\u1ef1c qu\u1ea3n v\u00e0 d\u1ea1 d\u00e0y \u1edf ng\u01b0\u1eddi.<\/p>","protected":false},"author":16,"featured_media":22408,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[21],"class_list":["post-22407","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-dr-martina-mikail"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What Is Stivarga (Regorafenib)? - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Essential information about Stivarga (Regorafenib). 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C\u00f4 t\u1ed1t nghi\u1ec7p \u0110\u1ea1i h\u1ecdc Marshall B. Ketchum v\u00e0o th\u00e1ng 5 n\u0103m 2022. Ti\u1ebfn s\u0129 Mikail l\u00e0 ng\u01b0\u1eddi nh\u1eadn Gi\u1ea3i th\u01b0\u1edfng L\u00e3nh \u0111\u1ea1o USPS v\u00e0 Gi\u1ea3i th\u01b0\u1edfng L\u00e3nh \u0111\u1ea1o CSHP, \u0111\u1ed3ng th\u1eddi l\u00e0 th\u00e0nh vi\u00ean t\u00edch c\u1ef1c c\u1ee7a CSHP, ASHP v\u00e0 APhA. Ph\u1ea7n b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a c\u00f4 l\u00e0 gi\u00e1o d\u1ee5c b\u1ec7nh nh\u00e2n v\u00e0 t\u01b0 v\u1ea5n cho h\u1ecd v\u1ec1 thu\u1ed1c. 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Unlike other cancer medications, Stivarga treats different types of cancers, including liver cancer, colorectal cancer, and a rare tumor that affects the human intestines, esophagus, and stomach.","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-150x150.jpg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-300x200.jpg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-1024x682.jpg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",600,400,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-330x220.jpg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-1146x380.jpg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-86x57.jpg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-167x111.jpg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-280x187.jpg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-370x247.jpg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2-960x640.jpg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/03\/Stivarga2.jpg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Martina Mikail, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/martina-mikail\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/discontinued\/\" rel=\"category tag\">Discontinued<\/a>","rttpg_excerpt":"Stivarga (generic name: regorafenib) is a drug used to treat cancer by preventing the growth and spread of malignant cells in the body. Unlike other cancer medications, Stivarga treats different types of cancers, including liver cancer, colorectal cancer, and a rare tumor that affects the human intestines, esophagus, and stomach.","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/22407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/comments?post=22407"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/22407\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media\/22408"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media?parent=22407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/categories?post=22407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/tags?post=22407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}