{"id":22278,"date":"2023-01-31T09:39:29","date_gmt":"2023-01-31T17:39:29","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=22278"},"modified":"2026-03-19T14:38:04","modified_gmt":"2026-03-19T21:38:04","slug":"what-is-inrebic-fedratinib","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/","title":{"rendered":"Inrebic (Fedratinib) l\u00e0 g\u00ec?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Inrebic l\u00e0 thu\u1ed1c ch\u1ed1ng ung th\u01b0 theo toa (\u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0) v\u00e0 c\u0169ng \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi t\u00ean chung l\u00e0 \u201c<\/span><span style=\"font-weight: 400;\">Fedratinib.\u201d Inrebic thu\u1ed9c nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 JAK<\/span><span style=\"font-weight: 400;\">2 (Kinase li\u00ean k\u1ebft Janus 2)<\/span><span style=\"font-weight: 400;\"> ch\u1ea5t \u1ee9c ch\u1ebf v\u00e0 \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o th\u00e1ng 8 n\u0103m 2019. Trong c\u00e1c \u0111i\u1ec1u ki\u1ec7n l\u00e2m s\u00e0ng, Inrebic \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ung th\u01b0 nguy\u00ean ph\u00e1t ho\u1eb7c th\u1ee9 ph\u00e1t c\u00f3 nguy c\u01a1 trung gian-2 ho\u1eb7c cao <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/myelofibrosis\/symptoms-causes\/syc-20355057#:~:text=Myelofibrosis%20is%20an%20uncommon%20type,can%20cause%20weakness%20and%20fatigue.\"><span style=\"font-weight: 400;\">x\u01a1 t\u1ee7y<\/span><\/a><span style=\"font-weight: 400;\"> \u1edf ng\u01b0\u1eddi l\u1edbn, c\u0169ng nh\u01b0 c\u00e1c tri\u1ec7u ch\u1ee9ng li\u00ean quan nh\u01b0 l\u00e1ch to (l\u00e1ch to).<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">X\u01a1 t\u1ee7y l\u00e0 m\u1ed9t d\u1ea1ng ung th\u01b0 m\u00e1u m\u00e3n t\u00ednh v\u00e0 hi\u1ebfm g\u1eb7p, trong \u0111\u00f3 t\u1ee7y x\u01b0\u01a1ng (m\u00f4 m\u1ec1m v\u00e0 x\u1ed1p b\u00ean trong x\u01b0\u01a1ng l\u1edbn) tr\u1edf n\u00ean \u0111\u1eb7c v\u00e0 x\u01a1 h\u00f3a do m\u1ed9t qu\u00e1 tr\u00ecnh g\u1ecdi l\u00e0 x\u01a1 h\u00f3a.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">V\u00ec t\u1ee7y x\u01b0\u01a1ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m s\u1ea3n xu\u1ea5t c\u00e1c th\u00e0nh ph\u1ea7n kh\u00e1c nhau c\u1ee7a m\u00e1u (v\u00ed d\u1ee5: h\u1ed3ng c\u1ea7u, b\u1ea1ch c\u1ea7u v\u00e0 ti\u1ec3u c\u1ea7u), x\u01a1 h\u00f3a s\u1ebd c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o m\u00e1u b\u00ecnh th\u01b0\u1eddng. K\u1ebft qu\u1ea3 l\u00e0, c\u00e1c t\u1ebf b\u00e0o m\u00e1u non \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t d\u01b0 th\u1eeba m\u1ed9t c\u00e1ch b\u1ea5t th\u01b0\u1eddng. Do t\u1ee7y x\u01b0\u01a1ng kh\u00f4ng th\u1ec3 s\u1ea3n xu\u1ea5t \u0111\u1ee7 t\u1ebf b\u00e0o m\u00e1u, l\u00e1ch s\u1ebd \u0111\u1ea3m nhi\u1ec7m m\u1ed9t ph\u1ea7n vi\u1ec7c s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o m\u00e1u, d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng l\u00e1ch to (l\u00e1ch to).&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Inrebic c\u00f3 d\u1ea1ng vi\u00ean nang u\u1ed1ng.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#What_Is_Inrebic_Used_To_Treat\" >Thu\u1ed1c Inrebic \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#How_Does_Inrebic_Work\" >Inrebic ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Mode_of_Action\" >Ch\u1ebf \u0111\u1ed9 h\u00e0nh \u0111\u1ed9ng<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Dosage_Form_and_Strength\" >D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Inrebic_Dosing_Information\" >Th\u00f4ng tin li\u1ec1u l\u01b0\u1ee3ng Inrebic<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#What_To_Do_if_You_Miss_a_Dose\" >Ph\u1ea3i l\u00e0m g\u00ec n\u1ebfu b\u1ea1n qu\u00ean m\u1ed9t li\u1ec1u<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#How_Is_Inrebic_Used\" >Inrebic \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Possible_Side_Effects_of_Inrebic\" >T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra c\u1ee7a Inrebic<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Common_Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Less_Common_Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Rare_But_Severe_Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p nh\u01b0ng nghi\u00eam tr\u1ecdng<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#Precaution_Recommendation\" >Th\u1eadn tr\u1ecdng &amp; Khuy\u1ebfn ngh\u1ecb<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/discontinued\/what-is-inrebic-fedratinib\/#US_Boxed_Warning_Encephalopathy_Including_Wernicke\" >C\u1ea3nh b\u00e1o \u0111\u00f3ng h\u1ed9p c\u1ee7a Hoa K\u1ef3: B\u1ec7nh n\u00e3o, bao g\u1ed3m c\u1ea3 Wernicke<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_Inrebic_Used_To_Treat\"><\/span>Thu\u1ed1c Inrebic \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Inrebic \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ba lo\u1ea1i b\u1ec7nh x\u01a1 t\u1ee7y bao g\u1ed3m:&nbsp;<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.leukaemia.org.au\/blood-cancer-information\/types-of-blood-cancer\/myeloproliferative-neoplasms\/primary-myelofibrosis\/#:~:text=What%20is%20Primary%20myelofibrosis%3F,to%20progressive%20bone%20marrow%20failure.\"><span style=\"font-weight: 400;\">X\u01a1 t\u1ee7y nguy\u00ean ph\u00e1t<\/span><\/a><span style=\"font-weight: 400;\"> (khi nguy\u00ean nh\u00e2n c\u01a1 b\u1ea3n ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft r\u00f5).<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">X\u01a1 t\u1ee7y sau b\u1ec7nh \u0111a h\u1ed3ng c\u1ea7u nguy\u00ean ph\u00e1t (m\u1ed9t c\u0103n b\u1ec7nh li\u00ean quan \u0111\u1ebfn t\u00ecnh tr\u1ea1ng t\u1ee7y x\u01b0\u01a1ng s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u b\u1ea5t th\u01b0\u1eddng).<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">B\u1ec7nh x\u01a1 t\u1ee7y sau ti\u1ec3u c\u1ea7u thi\u1ebft y\u1ebfu (m\u1ed9t c\u0103n b\u1ec7nh li\u00ean quan \u0111\u1ebfn t\u00ecnh tr\u1ea1ng s\u1ea3n xu\u1ea5t qu\u00e1 m\u1ee9c ti\u1ec3u c\u1ea7u \u1edf t\u1ee7y x\u01b0\u01a1ng).<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">V\u00ec nh\u1eefng c\u0103n b\u1ec7nh n\u00e0y \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n n\u00ean Inrebic \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0 \u201cthu\u1ed1c m\u1ed3 c\u00f4i\u201d.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_Inrebic_Work\"><\/span>Inrebic ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">\u1ede m\u1ed9t c\u00e1 th\u1ec3 kh\u1ecfe m\u1ea1nh, qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o m\u00e1u \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh ch\u1eb7t ch\u1ebd b\u1edfi <\/span><a href=\"https:\/\/medlineplus.gov\/genetics\/gene\/jak2\/\"><span style=\"font-weight: 400;\">JAK2<\/span><\/a><span style=\"font-weight: 400;\">, l\u00e0 m\u1ed9t lo\u1ea1i enzyme kinase th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t, ph\u00e2n chia v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o, trong \u0111\u00f3 c\u00f3 t\u1ebf b\u00e0o m\u00e1u trong t\u1ee7y x\u01b0\u01a1ng.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb x\u01a1 t\u1ee7y, enzyme JAK2 b\u1ecb ho\u1ea1t \u0111\u1ed9ng qu\u00e1 m\u1ee9c v\u00e0 g\u00e2y ra t\u00ecnh tr\u1ea1ng s\u1ea3n xu\u1ea5t b\u1ea5t th\u01b0\u1eddng c\u00e1c t\u1ebf b\u00e0o m\u00e1u ch\u01b0a tr\u01b0\u1edfng th\u00e0nh, k\u1ebft qu\u1ea3 l\u00e0 l\u00e1 l\u00e1ch s\u1ebd to ra \u0111\u00e1ng k\u1ec3.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Inrebic ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzyme JAK2 \u0111\u1ec3 l\u00e0m ch\u1eadm s\u1ef1 ph\u00e1t tri\u1ec3n b\u1ea5t th\u01b0\u1eddng c\u1ee7a c\u00e1c t\u1ebf b\u00e0o m\u00e1u v\u00e0 l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng li\u00ean quan \u0111\u1ebfn b\u1ec7nh x\u01a1 t\u1ee7y. Inrebic l\u00e0m gi\u1ea3m k\u00edch th\u01b0\u1edbc l\u00e1 l\u00e1ch, \u0111au x\u01b0\u01a1ng ho\u1eb7c c\u01a1, ng\u1ee9a, \u0111\u1ed5 m\u1ed3 h\u00f4i \u0111\u00eam, \u0111au d\u01b0\u1edbi x\u01b0\u01a1ng s\u01b0\u1eddn b\u00ean tr\u00e1i v\u00e0 kh\u00f3 ch\u1ecbu \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mode_of_Action\"><\/span>Ch\u1ebf \u0111\u1ed9 h\u00e0nh \u0111\u1ed9ng<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Inrebic ch\u1ee9a m\u1ed9t ch\u1ea5t ho\u1ea1t t\u00ednh, <\/span><span style=\"font-weight: 400;\">fedratinib,<\/span><span style=\"font-weight: 400;\"> c\u00f3 t\u00e1c d\u1ee5ng nh\u01b0 ch\u1ea5t \u1ee9c ch\u1ebf kinase v\u00e0 ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a enzyme JAK2.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosage_Form_and_Strength\"><\/span>D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Inrebic ch\u1ec9 c\u00f3 d\u1ea1ng vi\u00ean nang c\u1ee9ng 100 mg. <\/span><span style=\"font-weight: 400;\">Thu\u1ed1c n\u00e0y ch\u1ec9 c\u00f3 th\u1ec3 mua \u0111\u01b0\u1ee3c theo \u0111\u01a1n c\u1ee7a b\u00e1c s\u0129.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Inrebic_Dosing_Information\"><\/span>Th\u00f4ng tin li\u1ec1u l\u01b0\u1ee3ng Inrebic<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u khuy\u1ebfn c\u00e1o c\u1ee7a Inrebic cho ng\u01b0\u1eddi l\u1edbn l\u00e0 400 mg (b\u1ed1n vi\u00ean nang 100 mg) m\u1ed9t l\u1ea7n m\u1ed9t ng\u00e0y \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 s\u1ed1 l\u01b0\u1ee3ng ti\u1ec3u c\u1ea7u ban \u0111\u1ea7u l\u1edbn h\u01a1n ho\u1eb7c b\u1eb1ng 50.000\/mm3.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Tuy nhi\u00ean, li\u1ec1u Inrebic c\u00f3 th\u1ec3 c\u1ea7n gi\u1ea3m n\u1ebfu b\u1ec7nh nh\u00e2n b\u1ecb suy th\u1eadn ho\u1eb7c \u0111ang d\u00f9ng c\u00e1c thu\u1ed1c kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 thu\u1ed1c \u1ee9c ch\u1ebf CYP3A4 m\u1ea1nh. Vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u00e0y ph\u1ea3i do b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb th\u1ef1c hi\u1ec7n.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_To_Do_if_You_Miss_a_Dose\"><\/span>Ph\u1ea3i l\u00e0m g\u00ec n\u1ebfu b\u1ea1n qu\u00ean m\u1ed9t li\u1ec1u<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Tr\u00e1nh d\u00f9ng g\u1ea5p \u0111\u00f4i li\u1ec1u Inrebic \u0111\u1ec3 b\u00f9 cho li\u1ec1u \u0111\u00e3 qu\u00ean. N\u1ebfu b\u1ea1n qu\u00ean li\u1ec1u, h\u00e3y b\u1ecf qua li\u1ec1u \u0111\u00e3 qu\u00ean v\u00e0 d\u00f9ng li\u1ec1u ti\u1ebfp theo theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Inrebic_Used\"><\/span>Inrebic \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Vi\u00ean nang Inrebic \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n. Tuy nhi\u00ean, n\u1ebfu b\u1ea1n b\u1ecb kh\u00f3 ch\u1ecbu d\u1ea1 d\u00e0y ho\u1eb7c bu\u1ed3n n\u00f4n ho\u1eb7c n\u00f4n do thu\u1ed1c, h\u00e3y u\u1ed1ng Inrebic c\u00f9ng v\u1edbi b\u1eefa \u0103n nhi\u1ec1u ch\u1ea5t b\u00e9o \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 g\u1eb7p ph\u1ea3i c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u00e1c s\u0129 c\u00f3 th\u1ec3 \u0111\u1ec1 ngh\u1ecb d\u00f9ng c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c c\u00f9ng v\u1edbi Inrebic \u0111\u1ec3 ng\u0103n ng\u1eeba n\u00f4n m\u1eeda, ti\u00eau ch\u1ea3y ho\u1eb7c bu\u1ed3n n\u00f4n.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Vi\u00ean nang Inrebic ph\u1ea3i \u0111\u01b0\u1ee3c nu\u1ed1t nguy\u00ean vi\u00ean m\u00e0 kh\u00f4ng nhai ho\u1eb7c nghi\u1ec1n n\u00e1t.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Possible_Side_Effects_of_Inrebic\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 x\u1ea3y ra c\u1ee7a Inrebic<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Common_Side_Effects\"><\/span><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-22280 size-full\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver.jpg\" alt=\"liver with increased enzymes\" width=\"420\" height=\"280\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2023\/01\/liver-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/>T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">N\u00f4n m\u1eeda v\u00e0 bu\u1ed3n n\u00f4n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ti\u00eau ch\u1ea3y<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Thi\u1ebfu m\u00e1u<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">S\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o m\u00e1u th\u1ea5p (h\u1ed3ng c\u1ea7u v\u00e0 b\u1ea1ch c\u1ea7u), gi\u1ea3m t\u1ea1m th\u1eddi khi b\u1ea1n b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Inrebic. S\u1ef1 gi\u1ea3m n\u00e0y c\u00f3 th\u1ec3 khi\u1ebfn b\u1ea1n c\u00f3 nguy c\u01a1 nhi\u1ec5m tr\u00f9ng, thi\u1ebfu m\u00e1u ho\u1eb7c ch\u1ea3y m\u00e1u.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ee9c ti\u1ec3u c\u1ea7u trong m\u00e1u th\u1ea5p<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Natri m\u00e1u th\u1ea5p<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u0103ng men gan (ALT v\u00e0 AST)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Co th\u1eaft c\u01a1<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110i\u1ec3m y\u1ebfu<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u0103ng creatinin huy\u1ebft thanh<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Kh\u00f3 ti\u00eau<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ea5t c\u1ea3m gi\u00e1c th\u00e8m \u0103n&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110\u00e2y l\u00e0 nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 r\u1ea5t ph\u1ed5 bi\u1ebfn, ch\u1ec9 x\u1ea3y ra t\u1ea1m th\u1eddi v\u00e0 ho\u00e0n to\u00e0n c\u00f3 th\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c. V\u00ed d\u1ee5, bu\u1ed3n n\u00f4n v\u00e0 n\u00f4n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3m b\u1edbt b\u1eb1ng c\u00e1ch d\u00f9ng thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n. Lu\u00f4n lu\u00f4n tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c m\u1edbi n\u00e0o.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Less_Common_Side_Effects\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n d\u00f9ng Inrebic bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">M\u1ec7t m\u1ecfi<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au x\u01b0\u01a1ng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u0103ng enzyme amylase<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u1edf tay v\u00e0 ch\u00e2n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110au \u1edf t\u1ee9 chi<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u0103ng c\u00e2n<\/span><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Rare_But_Severe_Side_Effects\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p nh\u01b0ng nghi\u00eam tr\u1ecdng<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">C\u00e1c ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i hi\u1ebfm g\u1eb7p nh\u01b0ng c\u00f3 kh\u1ea3 n\u0103ng nghi\u00eam tr\u1ecdng (\u0111\u01b0\u1ee3c b\u00e1o c\u00e1o \u1edf ch\u01b0a \u0111\u1ebfn 1% b\u1ec7nh nh\u00e2n d\u00f9ng Inrebic) bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.ninds.nih.gov\/health-information\/disorders\/encephalopathy\">B\u1ec7nh n\u00e3o<\/a>, bao g\u1ed3m b\u1ec7nh n\u00e3o Wernicke, m\u1ed9t t\u00ecnh tr\u1ea1ng th\u1ea7n kinh do thi\u1ebfu vitamin B1 (thiamine). B\u1ec7nh nh\u00e2n g\u1eb7p c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1ecb l\u1ef1c, l\u00fa l\u1eabn, suy gi\u1ea3m tr\u00ed nh\u1edb, kh\u00f3 kh\u0103n trong v\u1eadn \u0111\u1ed9ng v\u00e0 ph\u1ed1i h\u1ee3p c\u01a1.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Huy\u1ebft kh\u1ed1i (<\/span><span style=\"font-weight: 400;\">huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u, thuy\u00ean t\u1eafc ph\u1ed5i v\u00e0 huy\u1ebft kh\u1ed1i \u0111\u1ed9ng m\u1ea1ch), x\u1ea3y ra \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf JAK kh\u00e1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb<\/span> <span style=\"font-weight: 400;\">vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p.<\/span><span style=\"font-weight: 400;\">&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110\u1ec3 tr\u00e1nh nh\u1eefng bi\u1ebfn ch\u1ee9ng nh\u01b0 v\u1eady, c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 vitamin B1 trong c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n (tr\u01b0\u1edbc ho\u1eb7c trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Inrebic).&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precaution_Recommendation\"><\/span>Th\u1eadn tr\u1ecdng &amp; Khuy\u1ebfn ngh\u1ecb<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Sau \u0111\u00e2y l\u00e0 m\u1ed9t s\u1ed1 khuy\u1ebfn ngh\u1ecb m\u00e0 b\u1ec7nh nh\u00e2n n\u00ean tu\u00e2n theo tr\u01b0\u1edbc ho\u1eb7c trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Inrebic:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Kh\u00f4ng d\u00f9ng Inrebic n\u1ebfu b\u1ea1n <\/span><b>\u0111ang mang thai ho\u1eb7c \u0111ang c\u00f3 k\u1ebf ho\u1ea1ch mang thai<\/b><span style=\"font-weight: 400;\">. Inrebic c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi v\u00ec thu\u1ed1c n\u00e0y \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 qua da v\u00e0 ph\u1ed5i.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Kh\u00f4ng d\u00f9ng Inrebic n\u1ebfu b\u1ea1n <\/span><b>\u0111ang cho con b\u00fa ho\u1eb7c d\u1ef1 \u0111\u1ecbnh cho con b\u00fa<\/b><span style=\"font-weight: 400;\">. V\u00ec ch\u01b0a bi\u1ebft thu\u1ed1c n\u00e0y c\u00f3 ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng n\u00ean khuy\u1ebfn c\u00e1o kh\u00f4ng n\u00ean cho con b\u00fa trong th\u1eddi gian d\u00f9ng thu\u1ed1c Inrebic.&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Tr\u00e1nh s\u1eed d\u1ee5ng Inrebic n\u1ebfu b\u1ea1n b\u1ecb d\u1ecb \u1ee9ng v\u1edbi <\/span><span style=\"font-weight: 400;\">fedratinib (m\u1ed9t th\u00e0nh ph\u1ea7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Inrebic) ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n kh\u00f4ng ho\u1ea1t \u0111\u1ed9ng n\u00e0o kh\u00e1c trong thu\u1ed1c n\u00e0y.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">H\u00e3y ch\u1eafc ch\u1eafn \u0111\u1ec3<\/span> <span style=\"font-weight: 400;\">h\u00e3y cho nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ea1n bi\u1ebft n\u1ebfu b\u1ea1n:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">C\u00f3 suy th\u1eadn ho\u1eb7c <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/an-overview-of-rheumatoid-arthritis\/\">vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p<\/a>.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">B\u1ecb b\u1ec7nh gan.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Thi\u1ebfu h\u1ee5t thiamine (vitamin B1).<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110ang d\u00f9ng th\u1ef1c ph\u1ea9m b\u1ed5 sung, vitamin ho\u1eb7c thu\u1ed1c \u1ee9c ch\u1ebf JAK kh\u00e1c.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"US_Boxed_Warning_Encephalopathy_Including_Wernicke\"><\/span><span style=\"font-weight: 400;\">C\u1ea3nh b\u00e1o \u0111\u00f3ng h\u1ed9p c\u1ee7a Hoa K\u1ef3: B\u1ec7nh n\u00e3o, bao g\u1ed3m c\u1ea3 Wernicke<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ec7nh n\u00e3o nghi\u00eam tr\u1ecdng v\u00e0 t\u1eed vong, bao g\u1ed3m c\u1ea3 Wernicke, \u0111\u00e3 x\u1ea3y ra \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng fedratinib. B\u1ec7nh n\u00e3o Wernicke l\u00e0 m\u1ed9t c\u1ea5p c\u1ee9u th\u1ea7n kinh. C\u1ea7n \u0111\u00e1nh gi\u00e1 n\u1ed3ng \u0111\u1ed9 thiamine \u1edf t\u1ea5t c\u1ea3 b\u1ec7nh nh\u00e2n tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u d\u00f9ng fedratinib, \u0111\u1ecbnh k\u1ef3 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u00e0 theo ch\u1ec9 \u0111\u1ecbnh l\u00e2m s\u00e0ng. Kh\u00f4ng b\u1eaft \u0111\u1ea7u d\u00f9ng fedratinib \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n thi\u1ebfu h\u1ee5t thiamine; c\u1ea7n b\u1ed5 sung thiamine \u0111\u1ea7y \u0111\u1ee7 tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. N\u1ebfu nghi ng\u1edd b\u1ec7nh n\u00e3o, h\u00e3y ng\u1eebng d\u00f9ng fedratinib ngay l\u1eadp t\u1ee9c v\u00e0 b\u1eaft \u0111\u1ea7u d\u00f9ng thiamine \u0111\u01b0\u1eddng ti\u00eam. Theo d\u00f5i cho \u0111\u1ebfn khi c\u00e1c tri\u1ec7u ch\u1ee9ng h\u1ebft ho\u1eb7c c\u1ea3i thi\u1ec7n v\u00e0 n\u1ed3ng \u0111\u1ed9 thiamine tr\u1edf v\u1ec1 b\u00ecnh th\u01b0\u1eddng.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Inrebic l\u00e0 thu\u1ed1c k\u00ea \u0111\u01a1n ch\u1ed1ng ung th\u01b0 (d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0) v\u00e0 c\u00f2n \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi t\u00ean g\u1ed1c l\u00e0 \u201cFedratinib\u201d. Inrebic thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf JAK2 (Janus Associated Kinase 2) v\u00e0 l\u1ea7n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn v\u00e0o th\u00e1ng 8 n\u0103m 2019.<\/p>","protected":false},"author":19,"featured_media":22279,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[64],"tags":[24],"class_list":["post-22278","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-discontinued","tag-rafik-boctor"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What Is Inrebic (Fedratinib)? - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn about Inrebic (Fedratinib). 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