{"id":22131,"date":"2022-12-06T12:43:53","date_gmt":"2022-12-06T20:43:53","guid":{"rendered":"https:\/\/ameripharmaspecialty.com\/?p=22131"},"modified":"2024-01-29T11:58:34","modified_gmt":"2024-01-29T11:58:34","slug":"nitisinone-orfadin-nityr","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/","title":{"rendered":"Nitisinone (Orfadin v\u00e0 Nityr)"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Nitisinone l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm g\u1eb7p v\u00e0 k\u00e9o d\u00e0i \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh tyrosin m\u00e1u di truy\u1ec1n lo\u1ea1i 1 (HT-1). B\u1ec7nh nh\u00e2n m\u1eafc <\/span><a href=\"https:\/\/rarediseases.org\/rare-diseases\/tyrosinemia-type-1\/#:~:text=Tyrosinemia%20type%20I%20is%20a,of%20the%20amino%20acid%20tyrosine.\"><span style=\"font-weight: 400;\">b\u1ec7nh tyrosin m\u00e1u lo\u1ea1i 1<\/span><\/a><span style=\"font-weight: 400;\"> th\u01b0\u1eddng kh\u00f4ng th\u1ec3 ph\u00e2n h\u1ee7y tyrosine (m\u1ed9t lo\u1ea1i axit amin) m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3 do thi\u1ebfu h\u1ee5t m\u1ed9t lo\u1ea1i enzyme c\u1ee5 th\u1ec3. S\u1ef1 th\u1ea5t b\u1ea1i c\u1ee7a qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y tyrosine d\u1eabn \u0111\u1ebfn<\/span><span style=\"font-weight: 400;\"> s\u1ef1 t\u00edch t\u1ee5<\/span><span style=\"font-weight: 400;\"> tyrosine v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u1ed9c h\u1ea1i c\u1ee7a n\u00f3 trong c\u00e1c m\u00f4 ho\u1eb7c c\u01a1 quan kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3. S\u1ef1 t\u00edch t\u1ee5 c\u00e1c th\u00e0nh ph\u1ea7n \u0111\u1ed9c h\u1ea1i n\u00e0y g\u00e2y ra t\u1ed5n th\u01b0\u01a1ng c\u01a1 quan nghi\u00eam tr\u1ecdng v\u00e0 ti\u1ebfn tri\u1ec3n, \u0111\u1eb7c bi\u1ec7t l\u00e0 ung th\u01b0 gan v\u00e0 th\u1eadn \u1edf b\u1ec7nh nh\u00e2n HT-1.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-7e06c678f99afca282b9d7ff3399a1a4\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tH\u1ecfi chuy\u00ean gia v\u1ec1 h\u1ed7 tr\u1ee3 \u0111\u1ed3ng thanh to\u00e1n\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<p><span style=\"font-weight: 400;\">Nitisinone l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh ti\u1ebfn tri\u1ec3n c\u1ee7a HT-1 b\u1eb1ng c\u00e1ch ng\u0103n ng\u1eeba s\u1ef1 h\u00ecnh th\u00e0nh v\u00e0 t\u00edch t\u1ee5 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u1ed9c h\u1ea1i trong gan v\u00e0 th\u1eadn.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Nitisinone \u0111\u01b0\u1ee3c b\u00e1n d\u01b0\u1edbi t\u00ean th\u01b0\u01a1ng hi\u1ec7u <\/span><span style=\"font-weight: 400;\">Orfadin v\u00e0 Nityr <\/span><span style=\"font-weight: 400;\">v\u00e0 ch\u1ec9 c\u00f3 th\u1ec3 mua \u0111\u01b0\u1ee3c theo \u0111\u01a1n c\u1ee7a b\u00e1c s\u0129.<\/span><\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Chuy\u1ec3n \u0111\u1ed5i m\u1ee5c l\u1ee5c\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Chuy\u1ec3n \u0111\u1ed5i<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#How_Does_Nitisinone_Treat_Hereditary_Tyrosinemia_Type-1_HT-1\" >Nitisinone \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Tyrosinemia di truy\u1ec1n lo\u1ea1i 1 (HT-1) nh\u01b0 th\u1ebf n\u00e0o?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Mode_of_Action\" >Ch\u1ebf \u0111\u1ed9 h\u00e0nh \u0111\u1ed9ng<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#How_Is_Nitisinone_Used\" >Nitisinone \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Dosage_Forms_and_Strengths\" >D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Dosing_Information\" >Th\u00f4ng tin li\u1ec1u l\u01b0\u1ee3ng<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Dose_Adjustment\" >\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Missed_Dose\" >Li\u1ec1u b\u1ecb qu\u00ean<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Method_of_Administration\" >Ph\u01b0\u01a1ng ph\u00e1p qu\u1ea3n l\u00fd<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#How_Should_I_Take_the_Nitisinone_Capsule\" >T\u00f4i n\u00ean d\u00f9ng vi\u00ean nang Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#How_Should_I_Take_Nitisinone_Oral_Suspension\" >T\u00f4i n\u00ean d\u00f9ng h\u1ed7n d\u1ecbch u\u1ed1ng Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#How_Should_I_Take_Nitisinone_Tablets\" >T\u00f4i n\u00ean d\u00f9ng vi\u00ean n\u00e9n Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Side_Effects\" >T\u00e1c d\u1ee5ng ph\u1ee5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Precautions_before_Taking_Nitisinone\" >Th\u1eadn tr\u1ecdng tr\u01b0\u1edbc khi d\u00f9ng Nitisinone<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Cost\" >Tr\u1ecb gi\u00e1<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Cost_of_Nitisinone_capsules\" >Gi\u00e1 c\u1ee7a vi\u00ean nang Nitisinone<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/nitisinone-orfadin-nityr\/#Cost_of_Nitisinone_Oral_suspension_4_mgml\" >Chi ph\u00ed c\u1ee7a Nitisinone d\u1ea1ng h\u1ed7n d\u1ecbch u\u1ed1ng (4 mg\/ml)<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Does_Nitisinone_Treat_Hereditary_Tyrosinemia_Type-1_HT-1\"><\/span>Nitisinone \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Tyrosinemia di truy\u1ec1n lo\u1ea1i 1 (HT-1) nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"420\" height=\"280\" src=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid.jpg\" alt=\"3D illustration of amino acid\" class=\"wp-image-22133\" srcset=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid.jpg 420w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-300x200.jpg 300w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-330x220.jpg 330w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-86x57.jpg 86w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-167x111.jpg 167w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-280x187.jpg 280w, https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/12\/amino-acid-370x247.jpg 370w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/figure>\n<\/div>\n\n\n<p><span style=\"font-weight: 400;\">Th\u00f4ng th\u01b0\u1eddng, c\u01a1 th\u1ec3 ch\u00fang ta ph\u00e2n h\u1ee7y protein th\u00e0nh c\u00e1c th\u00e0nh ph\u1ea7n nh\u1ecf h\u01a1n g\u1ecdi l\u00e0 axit amin. C\u00e1c axit amin n\u00e0y \u0111\u01b0\u1ee3c ph\u00e2n h\u1ee7y th\u00eam qua m\u1ed9t lo\u1ea1t c\u00e1c b\u01b0\u1edbc th\u00f4ng qua c\u00e1c enzyme kh\u00e1c nhau. <\/span><a href=\"https:\/\/medlineplus.gov\/genetics\/gene\/fah\/\"><span style=\"font-weight: 400;\">Hydrolase fumarylacetoacetate<\/span><\/a><span style=\"font-weight: 400;\">&nbsp;(FAH) l\u00e0 m\u1ed9t lo\u1ea1i enzyme c\u1ea7n thi\u1ebft cho qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y tyrosine v\u00e0 gi\u1ea3i ph\u00f3ng c\u00e1c ch\u1ea5t m\u00e0 c\u01a1 th\u1ec3 s\u1eed d\u1ee5ng \u0111\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c ch\u1ee9c n\u0103ng kh\u00e1c nhau.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Nh\u1eefng ng\u01b0\u1eddi sinh ra v\u1edbi HT-1 thi\u1ebfu enzyme FAH. C\u01a1 th\u1ec3 h\u1ecd ch\u1ec9 chuy\u1ec3n h\u00f3a m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf tyrosine v\u00e0 s\u1ea3n xu\u1ea5t m\u1ed9t l\u01b0\u1ee3ng l\u1edbn <\/span><span style=\"font-weight: 400;\">ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u1ed9c h\u1ea1i<\/span><span style=\"font-weight: 400;\">. Nitisinone ho\u1ea1t \u0111\u1ed9ng \u0111\u1ec3 ng\u0103n ch\u1eb7n con \u0111\u01b0\u1eddng ph\u00e2n h\u1ee7y tyrosine b\u1eb1ng c\u00e1ch ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t <\/span><b>ch\u1ea5t \u1ee9c ch\u1ebf<\/b><span style=\"font-weight: 400;\"> (m\u1ed9t th\u00e0nh ph\u1ea7n ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a enzyme).<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mode_of_Action\"><\/span>Ch\u1ebf \u0111\u1ed9 h\u00e0nh \u0111\u1ed9ng<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Nitisinone ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf <\/span><span style=\"font-weight: 400;\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/4-Hydroxyphenylpyruvate_dioxygenase\">hydroxyphenylpyruvate dioxygenase<\/a> (HPPD), m\u1ed9t enzyme tham gia v\u00e0o b\u01b0\u1edbc th\u1ee9 ba c\u1ee7a con \u0111\u01b0\u1eddng ph\u00e2n h\u1ee7y tyrosine. Nitisinone ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a enzyme th\u1ee9 ba n\u00e0y, do \u0111\u00f3 ph\u1ea3n \u1ee9ng s\u1ebd kh\u00f4ng ti\u1ebfp t\u1ee5c v\u00e0 kh\u00f4ng t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u1ed9c h\u1ea1i \u1edf b\u1ec7nh nh\u00e2n HT-1.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Is_Nitisinone_Used\"><\/span>Nitisinone \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">\u0110\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 hi\u1ec7u qu\u1ea3, nitisinone ph\u1ea3i \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n \u00edt protein v\u00e0 c\u00f3 h\u00e0m l\u01b0\u1ee3ng tyrosine v\u00e0 phenylalanine th\u1ea5p. Phenylalanine \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3 th\u00e0nh tyrosine; do \u0111\u00f3, khuy\u1ebfn c\u00e1o n\u00ean gi\u1ea3m th\u1ef1c ph\u1ea9m gi\u00e0u phenylalanine cho b\u1ec7nh nh\u00e2n HT-1. Phenylalanine c\u00f3 trong h\u1ea7u h\u1ebft c\u00e1c th\u1ef1c ph\u1ea9m gi\u00e0u protein nh\u01b0 s\u1eefa, ph\u00f4 mai, tr\u1ee9ng, c\u00e1c lo\u1ea1i h\u1ea1t, \u0111\u1eadu n\u00e0nh, th\u1ecbt b\u00f2, th\u1ecbt g\u00e0, th\u1ecbt l\u1ee3n, \u0111\u1eadu v\u00e0 c\u00e1.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">V\u00ec nitisinone v\u00e0 HT-1 g\u00e2y ra qu\u00e1 nhi\u1ec1u tyrosine trong m\u00e1u n\u00ean ch\u1ebf \u0111\u1ed9 \u0103n gi\u00e0u tyrosine c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 n\u00e3o, da v\u00e0 m\u1eaft.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosage_Forms_and_Strengths\"><\/span>D\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 n\u1ed3ng \u0111\u1ed9<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Nitisinone c\u00f3 d\u1ea1ng vi\u00ean n\u00e9n, h\u1ed7n d\u1ecbch u\u1ed1ng v\u00e0 vi\u00ean nang. M\u1ed7i d\u1ea1ng \u0111\u1ec1u \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 c\u00f3 c\u00e1c h\u00e0m l\u01b0\u1ee3ng nitisinone kh\u00e1c nhau:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>M\u00e1y t\u00ednh b\u1ea3ng <\/b><span style=\"font-weight: 400;\">c\u00f3 s\u1eb5n \u1edf li\u1ec1u l\u01b0\u1ee3ng 2 mg, 5 mg v\u00e0 10 mg.<\/span><\/li>\n\n\n\n<li><b>H\u1ed7n d\u1ecbch u\u1ed1ng<\/b><span style=\"font-weight: 400;\"> l\u00e0 m\u1ed9t h\u1ed7n d\u1ecbch m\u00e0u tr\u1eafng, h\u01a1i nh\u1edbt v\u00e0 \u0111\u1ee5c ch\u1ee9a 4 mg nitisinone\/ml (m\u1ed7i 1 ml ch\u1ee9a 4 mg nitisinone).<\/span><\/li>\n\n\n\n<li><b>Vi\u00ean nang c\u1ee9ng<\/b><span style=\"font-weight: 400;\"> ch\u1ee9a b\u1ed9t m\u00e0u tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0 c\u00f3 h\u00e0m l\u01b0\u1ee3ng 2 mg, 5 mg, 10 mg v\u00e0 20 mg nitisinone.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-7d387834d78aff1cf0c86ee1d2adff79\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tN\u00f3i chuy\u1ec7n v\u1edbi m\u1ed9t chuy\u00ean gia\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">L\u00ean l\u1ecbch t\u01b0 v\u1ea5n<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dosing_Information\"><\/span>Th\u00f4ng tin li\u1ec1u l\u01b0\u1ee3ng<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u l\u01b0\u1ee3ng nitisinone c\u00f3 th\u1ec3 kh\u00e1c nhau t\u00f9y theo t\u1eebng b\u1ec7nh nh\u00e2n v\u00e0 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh d\u1ef1a tr\u00ean c\u00e2n n\u1eb7ng v\u00e0 t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a h\u1ecd. Li\u1ec1u khuy\u1ebfn c\u00e1o <\/span><b>li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/b><span style=\"font-weight: 400;\"> d\u00e0nh cho b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em <\/span><b>0,5 mg\/kg<\/b><span style=\"font-weight: 400;\"> hai l\u1ea7n m\u1ed9t ng\u00e0y trong 4 tu\u1ea7n (1 th\u00e1ng).&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dose_Adjustment\"><\/span>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Li\u1ec1u l\u01b0\u1ee3ng nitisinone \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo n\u1ed3ng \u0111\u1ed9 succinylacetone (ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u1ed9c h\u1ea1i) trong huy\u1ebft thanh ho\u1eb7c n\u01b0\u1edbc ti\u1ec3u c\u1ee7a b\u1ec7nh nh\u00e2n HT-1. V\u00ed d\u1ee5:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">N\u1ebfu succinylacetone v\u1eabn c\u00f2n ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c trong huy\u1ebft thanh c\u1ee7a b\u1ec7nh nh\u00e2n HT-1 sau khi d\u00f9ng li\u1ec1u \u1ed5n \u0111\u1ecbnh (0,5 mg) trong b\u1ed1n tu\u1ea7n, th\u00ec li\u1ec1u d\u00f9ng s\u1ebd t\u0103ng t\u1eeb 0,5 \u0111\u1ebfn 0,75 mg\/kg, d\u00f9ng hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Khi succinylacetone kh\u00f4ng c\u00f2n ph\u00e1t hi\u1ec7n \u0111\u01b0\u1ee3c trong huy\u1ebft thanh c\u1ee7a b\u1ec7nh nh\u00e2n HT-1, li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo c\u00e2n n\u1eb7ng c\u1ee7a b\u1ec7nh nh\u00e2n. Li\u1ec1u t\u1ed1i \u0111a c\u1ee7a vi\u00ean nang nitisinone v\u00e0 h\u1ed7n d\u1ecbch u\u1ed1ng th\u01b0\u1eddng kh\u00f4ng qu\u00e1 <\/span><span style=\"font-weight: 400;\">1 ho\u1eb7c 2 mg\/kg tr\u1ecdng l\u01b0\u1ee3ng c\u01a1 th\u1ec3 <\/span><span style=\"font-weight: 400;\">v\u00e0 u\u1ed1ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y.&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe n\u1ebfu t\u00ecnh tr\u1ea1ng c\u1ee7a b\u1ea1n x\u1ea5u \u0111i sau khi chuy\u1ec3n li\u1ec1u t\u1eeb hai l\u1ea7n m\u1ed9t ng\u00e0y sang m\u1ed9t l\u1ea7n m\u1ed9t ng\u00e0y.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Missed_Dose\"><\/span>Li\u1ec1u b\u1ecb qu\u00ean<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n qu\u00ean li\u1ec1u nitisinone, h\u00e3y u\u1ed1ng ngay l\u1eadp t\u1ee9c. N\u1ebfu g\u1ea7n \u0111\u1ebfn gi\u1edd u\u1ed1ng li\u1ec1u ti\u1ebfp theo, h\u00e3y b\u1ecf qua li\u1ec1u \u0111\u00e3 qu\u00ean v\u00e0 ch\u1ec9 u\u1ed1ng li\u1ec1u ti\u1ebfp theo. Kh\u00f4ng u\u1ed1ng g\u1ea5p \u0111\u00f4i li\u1ec1u.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Method_of_Administration\"><\/span>Ph\u01b0\u01a1ng ph\u00e1p qu\u1ea3n l\u00fd<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Vi\u00ean n\u00e9n, vi\u00ean nang v\u00e0 h\u1ed7n d\u1ecbch u\u1ed1ng Nitisinone \u0111\u1ec1u \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng theo ch\u1ec9 d\u1eabn c\u1ee7a b\u00e1c s\u0129.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Should_I_Take_the_Nitisinone_Capsule\"><\/span>T\u00f4i n\u00ean d\u00f9ng vi\u00ean nang Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n n\u00ean u\u1ed1ng vi\u00ean nang nitisinone khi b\u1ee5ng \u0111\u00f3i, 1 gi\u1edd tr\u01b0\u1edbc b\u1eefa \u0103n ho\u1eb7c 2 gi\u1edd sau b\u1eefa \u0103n.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n g\u1eb7p kh\u00f3 kh\u0103n khi nu\u1ed1t c\u1ea3 vi\u00ean nang, b\u1ea1n c\u00f3 th\u1ec3 m\u1edf vi\u00ean nang v\u00e0 tr\u1ed9n thu\u1ed1c v\u1edbi m\u1ed9t th\u00eca n\u01b0\u1edbc, s\u1ed1t t\u00e1o ho\u1eb7c s\u1eefa c\u00f4ng th\u1ee9c. Nu\u1ed1t c\u1ea3 vi\u00ean nang m\u00e0 kh\u00f4ng c\u1ea7n nhai.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Should_I_Take_Nitisinone_Oral_Suspension\"><\/span>T\u00f4i n\u00ean d\u00f9ng h\u1ed7n d\u1ecbch u\u1ed1ng Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n s\u1ebd nh\u1eadn \u0111\u01b0\u1ee3c h\u1ed7n d\u1ecbch u\u1ed1ng nitisinone (d\u1ea1ng l\u1ecfng) trong l\u1ecd c\u00f9ng v\u1edbi \u1ed1ng ti\u00eam \u0111\u1ec3 l\u1ea5y \u0111\u00fang l\u01b0\u1ee3ng thu\u1ed1c t\u1eeb l\u1ecd.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">N\u1ebfu b\u1ea1n d\u00f9ng li\u1ec1u \u0111\u1ea7u ti\u00ean, h\u00e3y \u0111\u1ec3 chai h\u1ed7n d\u1ecbch \u1ea5m \u0111\u1ebfn nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng trong 30 \u0111\u1ebfn 60 ph\u00fat v\u00e0 l\u1eafc m\u1ea1nh trong 20 gi\u00e2y \u0111\u1ec3 nitisinone ph\u00e2n t\u00e1n \u0111\u1ec1u.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n c\u00f3 th\u1ec3 u\u1ed1ng h\u1ed7n d\u1ecbch u\u1ed1ng nitisinone c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Should_I_Take_Nitisinone_Tablets\"><\/span>T\u00f4i n\u00ean d\u00f9ng vi\u00ean n\u00e9n Nitisinone nh\u01b0 th\u1ebf n\u00e0o?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n c\u00f3 th\u1ec3 u\u1ed1ng vi\u00ean n\u00e9n nitisinone c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n. N\u1ebfu kh\u00f3 nu\u1ed1t c\u1ea3 vi\u00ean, b\u1ea1n c\u00f3 th\u1ec3 nghi\u1ec1n vi\u00ean thu\u1ed1c v\u00e0 tr\u1ed9n v\u1edbi m\u1ed9t th\u00eca n\u01b0\u1edbc, n\u01b0\u1edbc s\u1ed1t t\u00e1o ho\u1eb7c s\u1eefa c\u00f4ng th\u1ee9c. U\u1ed1ng ngay m\u00e0 kh\u00f4ng c\u1ea7n nhai.&nbsp;<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-1006fc11c30bb697726eeb518afa1470\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tNh\u1eadn tr\u1ee3 gi\u00fap \u0111\u1ed3ng thanh to\u00e1n\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tH\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_Effects\"><\/span>T\u00e1c d\u1ee5ng ph\u1ee5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Nitisinone c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng mong mu\u1ed1n. M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p v\u00e0 th\u01b0\u1eddng bi\u1ebfn m\u1ea5t trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. Tuy nhi\u00ean, trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p kh\u00e1c, t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng \u0111e d\u1ecda t\u00ednh m\u1ea1ng.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Sau \u0111\u00e2y l\u00e0 m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 b\u1ea1n c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i sau khi d\u00f9ng nitisinone d\u1ea1ng h\u1ed7n d\u1ecbch, vi\u00ean n\u00e9n ho\u1eb7c vi\u00ean nang:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u, ti\u00eau ch\u1ea3y ho\u1eb7c \u0111au d\u1ea1 d\u00e0y do h\u00e0m l\u01b0\u1ee3ng glycerol trong h\u1ed7n d\u1ecbch u\u1ed1ng nitisinone<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 n\u1ed5i m\u1ec1 \u0111ay; ph\u00e1t ban; v\u00e0 s\u01b0ng m\u00f4i, l\u01b0\u1ee1i v\u00e0 c\u1ed5 h\u1ecdng<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">T\u00f3c m\u1ecfng \u0111i<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Th\u1ecb l\u1ef1c thay \u0111\u1ed5i v\u00e0 m\u1eaft tr\u1edf n\u00ean nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng (<a href=\"https:\/\/www.mountsinai.org\/health-library\/symptoms\/photophobia#:~:text=Photophobia%20is%20eye%20discomfort%20in,through%20to%20change%20pupil%20size.\">s\u1ee3 \u00e1nh s\u00e1ng<\/a>)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1eaft \u0111\u1ecf, k\u00edch \u1ee9ng v\u00e0 \u0111au&nbsp;<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Ch\u1ea3y m\u00e1u m\u0169i<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng h\u01a1n, khi b\u1ea1n kh\u00f4ng tu\u00e2n th\u1ee7 ch\u1ebf \u0111\u1ed9 \u0103n h\u1ea1n ch\u1ebf tyrosine v\u00e0 phenylalanine, b\u1ea1n c\u00f3 th\u1ec3 g\u1eb7p m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 b\u1ea5t l\u1ee3i do n\u1ed3ng \u0111\u1ed9 tyrosine t\u0103ng cao, c\u00f3 li\u00ean quan \u0111\u1ebfn \u0111\u1ed9c t\u00ednh \u0111\u1ed1i v\u1edbi m\u1eaft, da v\u00e0 h\u1ec7 th\u1ea7n kinh. C\u00e1c tri\u1ec7u ch\u1ee9ng b\u1ea5t l\u1ee3i bao g\u1ed3m:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Da kh\u00f4<\/span><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Vi\u00eam gi\u00e1c m\u1ea1c (lo\u00e9t gi\u00e1c m\u1ea1c)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110\u1ed9 m\u1edd gi\u00e1c m\u1ea1c<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110\u1ee5c th\u1ee7y tinh th\u1ec3<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Vi\u00eam k\u1ebft m\u1ea1c (\u0111au m\u1eaft \u0111\u1ecf)<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">M\u1ea3ng da d\u00e0y g\u00e2y \u0111au (m\u1ea3ng s\u1eebng h\u00f3a) \u1edf l\u00f2ng b\u00e0n tay ho\u1eb7c l\u00f2ng b\u00e0n ch\u00e2n<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Gi\u1ea3m b\u1ea1ch c\u1ea7u v\u00e0 nghi\u00eam tr\u1ecdng <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/14430-thrombocytopenia\">gi\u1ea3m ti\u1ec3u c\u1ea7u<\/a>&nbsp;<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Precautions_before_Taking_Nitisinone\"><\/span>Th\u1eadn tr\u1ecdng tr\u01b0\u1edbc khi d\u00f9ng Nitisinone<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Trong khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng nitisinone, b\u1ea1n n\u00ean \u00e1p d\u1ee5ng ch\u1ebf \u0111\u1ed9 \u0103n h\u1ea1n ch\u1ebf l\u01b0\u1ee3ng tyrosine v\u00e0 phenylalanine n\u1ea1p v\u00e0o.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">B\u1ea1n <\/span><b>KH\u00d4NG N\u00caN<\/b><span style=\"font-weight: 400;\"> d\u00f9ng nitisinone n\u1ebfu b\u1ea1n:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">\u0110ang mang thai ho\u1eb7c c\u00f3 \u00fd \u0111\u1ecbnh th\u1ee5 thai.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">\u0110ang cho con b\u00fa ho\u1eb7c c\u00f3 k\u1ebf ho\u1ea1ch cho con b\u00fa.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">B\u1ecb d\u1ecb \u1ee9ng v\u1edbi nitisinone ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">C\u00f3 ti\u1ec1n s\u1eed m\u1eafc c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 m\u1eaft (nh\u01b0 \u0111\u1ee5c th\u1ee7y tinh th\u1ec3 ho\u1eb7c lo\u00e9t gi\u00e1c m\u1ea1c).<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost\"><\/span>Tr\u1ecb gi\u00e1<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Chi ph\u00ed c\u1ee7a vi\u00ean nang, vi\u00ean n\u00e9n v\u00e0 h\u1ed7n d\u1ecbch u\u1ed1ng nitisinone thay \u0111\u1ed5i t\u00f9y thu\u1ed9c v\u00e0o <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/\">hi\u1ec7u thu\u1ed1c<\/a> b\u1ea1n gh\u00e9 th\u0103m. Sau \u0111\u00e2y l\u00e0 gi\u00e1 c\u1ee7a vi\u00ean nang v\u00e0 h\u1ed7n d\u1ecbch nitisinone v\u1edbi c\u00e1c n\u1ed3ng \u0111\u1ed9 kh\u00e1c nhau.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost_of_Nitisinone_capsules\"><\/span>Gi\u00e1 c\u1ee7a vi\u00ean nang Nitisinone<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Nitisinone <\/span><b>2 mg<\/b><span style=\"font-weight: 400;\"> gi\u00e1 m\u1ed9t vi\u00ean nang kho\u1ea3ng $5.748 ($95,80 cho m\u1ed9t vi\u00ean nang) cho 60 vi\u00ean nang.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nitisinone<\/span><b> 5 mg<\/b><span style=\"font-weight: 400;\"> gi\u00e1 m\u1ed9t vi\u00ean nang kho\u1ea3ng $14.354,93 ($239,25 cho m\u1ed9t vi\u00ean nang) cho 60 vi\u00ean nang.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nitisinone <\/span><b>10 mg<\/b><span style=\"font-weight: 400;\"> gi\u00e1 m\u1ed9t vi\u00ean nang kho\u1ea3ng $28.700,39 ($478,34 cho m\u1ed9t vi\u00ean nang) cho 60 vi\u00ean nang.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Nitisinone <\/span><b>20 mg<\/b><span style=\"font-weight: 400;\"> vi\u00ean nang c\u00f3 gi\u00e1 kho\u1ea3ng $57,391.27 <\/span><span style=\"font-weight: 400;\">($956.52<\/span><span style=\"font-weight: 400;\"> m\u1ed7i vi\u00ean nang<\/span><span style=\"font-weight: 400;\">) \u0111\u1ec3 cung c\u1ea5p 60 vi\u00ean nang.<\/span><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost_of_Nitisinone_Oral_suspension_4_mgml\"><\/span>Chi ph\u00ed c\u1ee7a Nitisinone d\u1ea1ng h\u1ed7n d\u1ecbch u\u1ed1ng (4 mg\/ml)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Gi\u00e1 h\u1ed7n d\u1ecbch u\u1ed1ng Nitisinone kho\u1ea3ng $18.772,78 cho 90 ml.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Chi ph\u00ed c\u1ee7a vi\u00ean n\u00e9n nitisinone kh\u00f4ng ph\u1ea3i l\u00e0 <\/span><span style=\"font-weight: 400;\">c\u00f3 s\u1eb5n cho c\u00f4ng ch\u00fang.&nbsp;<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Nitisinone l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t ch\u1ee9ng r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm g\u1eb7p v\u00e0 k\u00e9o d\u00e0i su\u1ed1t \u0111\u1eddi g\u1ecdi l\u00e0 b\u1ec7nh tyrosinemia di truy\u1ec1n lo\u1ea1i 1 (HT-1). B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh tyrosinemia lo\u1ea1i 1 th\u01b0\u1eddng kh\u00f4ng th\u1ec3 ph\u00e2n gi\u1ea3i tyrosine (m\u1ed9t axit amin) m\u1ed9t c\u00e1ch \u0111\u00fang c\u00e1ch do thi\u1ebfu h\u1ee5t m\u1ed9t lo\u1ea1i enzyme c\u1ee5 th\u1ec3.<\/p>","protected":false},"author":21,"featured_media":22132,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[4],"tags":[27],"class_list":["post-22131","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other-health-conditions","tag-dr-abdelaziz-alsamarah"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nitisinone (Orfadin and Nityr) - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Learn about Nitisinone (Orfadin and Nityr) and how it treats hereditary tyrosinemia type-1 (HT-1). 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