{"id":20067,"date":"2022-05-05T09:59:55","date_gmt":"2022-05-05T16:59:55","guid":{"rendered":"https:\/\/ameripharmaspe.wpengine.com\/staging\/?p=19095"},"modified":"2026-03-26T14:07:07","modified_gmt":"2026-03-26T21:07:07","slug":"necrotizing-myopathy","status":"publish","type":"post","link":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/","title":{"rendered":"B\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed"},"content":{"rendered":"\n<p>The term \u201cmyopathy\u201d generally means muscle weakness, while the term \u201cnecrotizing\u201d means cell death and necrosis. Necrotizing myopathy, also known as necrotizing autoimmune myopathy (NAM) or immune-mediated necrotizing myopathy (IMNM), is characterized by cell death and necrosis of muscle cells, particularly the muscles closer to the center of the body. This causes generalized muscle weakness and difficulty moving. It is considered a very rare form of idiopathic inflammatory myopathy, in which muscle biopsy typically shows prominent muscle fiber necrosis with minimal inflammatory cell infiltration. Although classified as an inflammatory myopathy, necrosis predominates over visible inflammation on histopathology. This particular form is quite rare, but the incidence is increasing due to the increased rate of detection. Currently, the incidence rate of all idiopathic inflammatory myopathies is about 1.16 to 19 cases per million people per year, and necrotizing myopathy represents approximately 10% of these cases [<a href=\"https:\/\/www.orpha.net\/en\/disease\/detail\/206569\">1<\/a>].<\/p>\n\n\n\n<div  id=\"call-to-action-78b0349a9eb9352465bc278678d99702\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet IVIG Prior Authorization\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#What_Causes_Necrotizing_Myopathy\" >What Causes Necrotizing Myopathy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Signs_And_Symptoms_Of_Myopathy\" >Signs And Symptoms Of Myopathy&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#How_Can_Immune-Mediated_Necrotizing_Myopathy_Be_Diagnosed\" >How Can Immune-Mediated Necrotizing Myopathy Be Diagnosed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Categories_of_Necrotizing_Myopathies\" >Categories of Necrotizing Myopathies<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Patients_with_SRP_Autoantibodies\" >Patients with SRP Autoantibodies<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Patients_with_HMGCR_Autoantibodies\" >Patients with HMGCR Autoantibodies<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#All_Other_Patients\" >All Other Patients<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Is_Necrotizing_Autoimmune_Myopathy_Painful\" >Is Necrotizing Autoimmune Myopathy Painful?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Can_You_Recover_From_Necrotizing_Myopathy\" >Can You Recover From Necrotizing Myopathy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#What_Is_The_Treatment_For_Necrotizing_Myopathy\" >What Is The Treatment For Necrotizing Myopathy?&nbsp;<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Removal_of_the_Cause\" >Removal of the Cause<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Corticosteroids_Therapy\" >Corticosteroids Therapy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Immuno-suppressive_therapy\" >Immuno-suppressive therapy&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Immunoglobulin_therapy\" >Immunoglobulin therapy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Exercise\" >Exercise<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Diet_and_Nutrition\" >Diet and Nutrition<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/#Is_Necrotizing_Myopathy_Fatal\" >Is Necrotizing Myopathy Fatal?<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Causes_Necrotizing_Myopathy\"><\/span><span style=\"font-weight: 400;\">What Causes Necrotizing Myopathy?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">The exact cause is poorly understood, but necrotizing myopathy is thought to be an autoimmune disorder. In an autoimmune disorder, a certain trigger stimulates the body to attack its own cells and tissues. The triggers that can lead to necrotizing autoimmune myopathy include:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b>Statins:<\/b><span style=\"font-weight: 400;\"> A group of drugs used to control the level of cholesterol in the body.<\/span><\/li>\n\n\n\n<li><b>Cancer:<\/b><span style=\"font-weight: 400;\"> Certain types of cancers are associated with necrotizing myopathy.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Connective tissue disease:<\/b><span style=\"font-weight: 400;\"> This is a disease that affects the connective tissue (the tissue that connects all the parts of the body together). Necrotizing myopathy may overlap with other autoimmune connective tissue diseases due to shared immune-mediated mechanisms, rather than because of the structural composition of muscle tissue.<\/span><\/li>\n\n\n\n<li><b>HIV:<\/b><span style=\"font-weight: 400;\"> HIV is a virus that reduces the immune response of the body to almost every foreign object, germ, or bacteria. In some cases, the body reacts to HIV infection by attacking its own cells, including muscle cells, causing myopathy.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Signs_And_Symptoms_Of_Myopathy\"><\/span><span style=\"font-weight: 400;\">Signs And Symptoms Of Myopathy&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Almost all types of myopathy present with similar symptoms, making it difficult to distinguish the type of myopathy without further testing.&nbsp;<\/span><span data-preserver-spaces=\"true\">Patients who have necrotizing myopathy may experience symptoms such as the following:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span data-preserver-spaces=\"true\">Weakness in the muscles closest to the middle of the body, such as the shoulders, forearms, thighs, hips, neck, and back.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Difficulty standing up from a chair.<\/span><\/li>\n\n\n\n<li>Difficulty <span data-preserver-spaces=\"true\">climbing stairs.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Falling or difficulty getting up from a fall.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Difficulty raising arms over the head.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">A general feeling of tiredness.<\/span><\/li>\n<\/ul>\n\n\n\n<p><span style=\"font-weight: 400;\">Other muscles may be affected as well, although far less commonly. These include:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-weight: 400;\">Muscles of the neck, causing difficulty in head and neck movement.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Muscles of the throat, causing difficulty swallowing or voice changes.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Chest muscles, causing difficulty breathing.<\/span><\/li>\n\n\n\n<li><span style=\"font-weight: 400;\">Muscles of the heart.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_Can_Immune-Mediated_Necrotizing_Myopathy_Be_Diagnosed\"><\/span><span style=\"font-weight: 400;\">How Can Immune-Mediated Necrotizing Myopathy Be Diagnosed?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><b><a href=\"https:\/\/jnnp.bmj.com\/content\/76\/suppl_2\/ii32\">Electromyography<\/a>: <\/b><span style=\"font-weight: 400;\">This is an electrical test of the muscles to check their strength. These tests usually show myopathic symptoms (meaning symptoms of weakness) but are not particularly indicative of the cause or type of myopathy.<\/span><\/li>\n\n\n\n<li><b>Blood markers: <\/b>Blood tests show autoimmune markers, mainly SRP and HMGCR autoantibodies. These are autoimmune antibodies produced when the body is exposed to the above-mentioned triggers and are possibly the main cause. Highly elevated levels (up to 10 times the normal levels) of creatine kinase enzyme can also be seen. However, seronegative findings (meaning no change in the blood markers and antibodies) are<span style=\"font-weight: 400;\"> common in 20% of patients, so blood tests should not be a definitive determinant of the absence of the disease.<\/span><\/li>\n\n\n\n<li><b>MRI: <\/b><span style=\"font-weight: 400;\">Magnetic resonance imaging (MRI) is a commonly used test to check the condition of soft tissues. With necrotizing myopathy, muscles show signs of edema.&nbsp;<\/span><\/li>\n\n\n\n<li><b>Muscle Biopsy: <\/b><span style=\"font-weight: 400;\">This is the most definitive test of necrotizing myopathy, where a small sample is taken and analyzed.\u00a0 It is the only test that can differentiate it from other idiopathic inflammatory myopathies (IM) or <a href=\"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/polymyositis\/\">polymyositis<\/a> (PM), whose signs and symptoms are nearly indistinguishable from one another. Unlike polymyositis and other inflammatory myopathies, immune-mediated necrotizing myopathy shows prominent muscle fiber necrosis with relatively sparse inflammatory infiltrates on biopsy. Inflammation is still present at a molecular level, but it is less visible under the microscope compared to other inflammatory myopathies.<\/span><\/li>\n\n\n\n<li><b>Cancer Screening:<\/b> <span style=\"font-weight: 400;\">Since cancer could be associated with some cases, cancer screenings may be performed.<\/span><\/li>\n<\/ul>\n\n\n\n<div  id=\"call-to-action-fa32dcc4fd975627faf003d3b1ae1af0\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet IVIG Copay Assistance\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tSpeak to a Specialist\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Consult an IVIG Specialist<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Categories_of_Necrotizing_Myopathies\"><\/span><span style=\"font-weight: 400;\">Categories of Necrotizing Myopathies<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Researchers are beginning to distinguish three different categories of necrotizing myopathy. Each has different treatments and risk factors. The categories are based on the presence of different autoantibodies found in the blood.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Patients_with_SRP_Autoantibodies\"><\/span>Patients with SRP Autoantibodies<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4440264\/#:~:text=Anti%2Dsignal%20recognition%20particle%20(SRP,antibodies%20seems%20to%20be%20broad.\">SRP autoantibodies<\/a> appear in blood tests of many people who have symptoms of necrotizing myopathy. Sudden and extreme muscle weakness can occur, and there may also be cardiac involvement.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Patients_with_HMGCR_Autoantibodies\"><\/span>Patients with HMGCR Autoantibodies<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>HMGCR is a key enzyme in the production of cholesterol. Patients who have <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27618830\/#:~:text=Anti%2DHMGCR%20antibodies%20represent%20a,with%20other%20autoimmune%20rheumatic%20diseases.\">HMGCR autoantibodies<\/a> and use statin medications for high cholesterol may develop this kind of statin-induced necrotizing myopathy.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"All_Other_Patients\"><\/span>All Other Patients<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>All other patients are classified by some experts in a third, separate group of necrotizing myopathy. These patients do not have SRP or HMGCR autoantibodies.<\/p>\n\n\n\n<p>Prognosis may vary between subtypes. Patients with anti-SRP antibodies often experience more severe and rapidly progressive weakness and may be more resistant to treatment. Patients with anti-HMGCR antibodies, particularly those with statin exposure, often respond well to immunotherapy, especially when diagnosed early. Early treatment is associated with better functional outcomes in all subtypes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Is_Necrotizing_Autoimmune_Myopathy_Painful\"><\/span><span style=\"font-weight: 400;\">Is Necrotizing Autoimmune Myopathy Painful?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Since myopathy is a disease of the muscles, myalgia (muscle pain) is often an accompanying symptom. Muscle pain may result from ongoing muscle fiber damage, inflammatory mediators, and immune system activity within the muscle tissue. Pain may also develop due to muscle fatigue, deconditioning, and secondary strain from weakened muscle groups.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_You_Recover_From_Necrotizing_Myopathy\"><\/span><span style=\"font-weight: 400;\">Can You Recover From Necrotizing Myopathy?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">There is no known cure for necrotizing myopathy. Since the problem lies within the body\u2019s immune system being sensitized to attack the body\u2019s cells, it is not possible to cure such a disease as you cannot turn off a patient\u2019s immune system. However, the condition can be controlled, and patients can lead a normal life in most cases.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_The_Treatment_For_Necrotizing_Myopathy\"><\/span><span style=\"font-weight: 400;\">What Is The Treatment For Necrotizing Myopathy?&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Treatment of immune-mediated necrotizing myopathy is often a multifold approach:<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Removal_of_the_Cause\"><\/span><span style=\"font-weight: 400;\">Removal of the Cause<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">While some cases have no apparent cause, most cases come with one of the associated triggers mentioned above. Removal of the cause ensures the problem does not progress. Patients on statin therapy must consult their physician to stop or change their drugs. Patients who have cancer should discuss the best options available to control both diseases simultaneously. Treatment for connective tissue disease and HIV infections usually involves corticosteroids.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Corticosteroids_Therapy\"><\/span><span style=\"font-weight: 400;\">Corticosteroids Therapy<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Corticosteroids are the main line of treatment. They suppress the immune response and reduce the production of inflammatory cytokines, helping to limit further muscle damage. The initial dose is usually high, but it is then reduced to a maintenance dose.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Since steroids, especially over prolonged periods, have many adverse side effects (i.e., weight gain, elevated blood sugars, thinning of skin), the introduction of steroid-sparing medications will be considered by your doctor.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Additional drugs to suppress the immune system may be added to steroids, sometimes at the beginning of treatment and other times after it has been determined that steroids are effective.<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Immuno-suppressive_therapy\"><\/span><span style=\"font-weight: 400;\">Immuno-suppressive therapy&nbsp;<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Since the main problem is with the immune system, immunosuppressive drugs are often needed. The most commonly used drugs are methotrexate, mycophenolate mofetil, azathioprine, and rituximab. Immunosuppressive drugs can be used individually or, more commonly, in combination with corticosteroids to yield the best results. They are used for the initial treatment period, and the patient may or may not need a maintenance dose afterward.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-415cc88851f79fa14f3551d0a6c5dafe\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tGet Your IVIG Dose\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tAt-Home Infusion\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"tel:8777780318\">(877) 778-0318<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Immunoglobulin_therapy\"><\/span><span style=\"font-weight: 400;\">Immunoglobulin therapy<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/immunoglobulins-ig\/\">Immunoglobulin<\/a> comes from antibodies extracted from plasma from thousands of blood donors. <a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/ivig\/\/ivig\/\">IVIG<\/a> is the intravenous method, and SCIG is given subcutaneously under the skin.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Some studies have shown that statin-exposed HMGCR autoantibody-positive patients have improved dramatically with IVIG, whereas statin-naive HMGCR autoantibody patients may be refractory to <a href=\"https:\/\/ameripharmaspecialty.com\/ivig\/what-to-expect-during-your-ivig-infusion-treatment\/\">immunoglobulin therapy<\/a>.&nbsp;<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Exercise\"><\/span><span style=\"font-weight: 400;\">Exercise<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Staying in shape to keep muscles strong is an essential aspect of the treatment of necrotizing myositis. This may be difficult initially with the generalized muscle weakness and inability to move normally, but with treatment, movement becomes easier, and physical exercise must become part of the treatment routine. Your doctor may start by referring you to physical therapy or a rehabilitation center. An exercise plan curated by your healthcare team is most effective and ensures that you do not injure yourself.\u00a0<\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diet_and_Nutrition\"><\/span><span style=\"font-weight: 400;\">Diet and Nutrition<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><span style=\"font-weight: 400;\">Eating a well-balanced diet may be beneficial for overall health for those with necrotizing myositis.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Treatment with corticosteroids has many side effects, including weight gain and elevated blood sugars, so your diet may need to be adjusted for these conditions.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">There is no single medication or treatment timeline as response differs from patient to patient. However, treatment is considered successful when signs and symptoms diminish and the range of motion increases. Success is also indicated serologically by the reduction in the amount of creatine kinase in the blood.<\/span><\/p>\n\n\n\n<div  id=\"call-to-action-6e03ffd69bfc2682f1a612579d7e57c6\" style=\"\" class=\"ct_call_to_action\">\n\t<div class=\"container\">\n\t\t<div class=\"block-wrap cta\">\n\t\t\t<div class=\"block-column\">\n\t\t\t\t<div class=\"cta_headings\">\n\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"cta__heading\">\n\t\t\t\t\t\t\tHome Infusion\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cta__sub__heading\">\n\t\t\t\t\t\t\tWe Come To You\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<span class=\"cta_btn\">\n\t\t\t\t\t\t<a href=\"#form\">Schedule a Consultation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Is_Necrotizing_Myopathy_Fatal\"><\/span><span style=\"font-weight: 400;\">Is Necrotizing Myopathy Fatal?<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Necrotizing myopathy is a newly defined form of myopathy. Long-term outcomes vary depending on subtype, severity at presentation, and response to treatment. However, the disease mostly affects the proximal muscles, so muscle weakness is common and, in most cases, not life-threatening. Very few cases report muscle weakness in more essential muscles such as chest muscles, throat muscles, and cardiac muscles. In these cases, patients presented with more severe symptoms of shortness of breath, difficulty eating, and cardiac <a href=\"https:\/\/www.nhlbi.nih.gov\/health\/arrhythmias\">arrhythmia<\/a>. Correct diagnosis is essential for these cases, which may lead to serious complications if not promptly recognized and treated. However, if correctly treated, improvement of the symptoms usually occurs quickly.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1eadt ng\u1eef \u201cb\u1ec7nh c\u01a1\u201d th\u01b0\u1eddng c\u00f3 ngh\u0129a l\u00e0 y\u1ebfu c\u01a1, trong khi thu\u1eadt ng\u1eef \u201cho\u1ea1i t\u1eed\u201d c\u00f3 ngh\u0129a l\u00e0 ch\u1ebft t\u1ebf b\u00e0o v\u00e0 ho\u1ea1i t\u1eed. B\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh c\u01a1 t\u1ef1 mi\u1ec5n ho\u1ea1i t\u1eed (NAM) ho\u1eb7c b\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed do mi\u1ec5n d\u1ecbch (IMNM), \u0111\u01b0\u1ee3c \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 ch\u1ebft t\u1ebf b\u00e0o v\u00e0 ho\u1ea1i t\u1eed c\u1ee7a c\u00e1c t\u1ebf b\u00e0o c\u01a1, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c c\u01a1 g\u1ea7n trung t\u00e2m c\u01a1 th\u1ec3.<\/p>","protected":false},"author":9,"featured_media":20068,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[49,4],"tags":[9],"class_list":["post-20067","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hiv","category-other-health-conditions","tag-dr-stephanie-shieh"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Necrotizing Myopathy - AmeriPharma\u00ae Specialty Care<\/title>\n<meta name=\"description\" content=\"Explore the causes, symptoms, and best treatments for necrotizing myopathy. Get the support and information you need to manage your condition more effectively.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Necrotizing Myopathy - AmeriPharma\u00ae Specialty Care\" \/>\n<meta property=\"og:description\" content=\"Explore the causes, symptoms, and best treatments for necrotizing myopathy. Get the support and information you need to manage your condition more effectively.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/\" \/>\n<meta property=\"og:site_name\" content=\"AmeriPharma\u00ae Specialty Care\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ameripharma\/\" \/>\n<meta property=\"article:published_time\" content=\"2022-05-05T16:59:55+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-26T21:07:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"853\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Dr. Stephanie Shieh, PharmD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dr. Stephanie Shieh, PharmD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 ph\u00fat\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/\"},\"author\":{\"name\":\"Dr. Stephanie Shieh, PharmD\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#\\\/schema\\\/person\\\/fa3e6923d70031df69b97d6c635ff5c8\"},\"headline\":\"Necrotizing Myopathy\",\"datePublished\":\"2022-05-05T16:59:55+00:00\",\"dateModified\":\"2026-03-26T21:07:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/\"},\"wordCount\":1598,\"publisher\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/necrotizing-myopathy.jpeg\",\"keywords\":[\"Dr. Stephanie Shieh\"],\"articleSection\":[\"HIV\",\"Other Health Conditions\"],\"inLanguage\":\"vi\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/\",\"name\":\"Necrotizing Myopathy - AmeriPharma\u00ae Specialty Care\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/necrotizing-myopathy.jpeg\",\"datePublished\":\"2022-05-05T16:59:55+00:00\",\"dateModified\":\"2026-03-26T21:07:07+00:00\",\"description\":\"Explore the causes, symptoms, and best treatments for necrotizing myopathy. Get the support and information you need to manage your condition more effectively.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#breadcrumb\"},\"inLanguage\":\"vi\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"vi\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/necrotizing-myopathy.jpeg\",\"contentUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/necrotizing-myopathy.jpeg\",\"width\":1280,\"height\":853,\"caption\":\"Close-up of a patient\u2019s leg with visible muscle inflammation, representing necrotizing myopathy.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/other-health-conditions\\\/necrotizing-myopathy\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Necrotizing Myopathy\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#website\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/\",\"name\":\"AmeriPharma\u00ae Specialty Care\",\"description\":\"Specialty Care by AmeriPharma\",\"publisher\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"vi\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#organization\",\"name\":\"Ameripharma Specialty Care\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"vi\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/specialty-care-logo-large-square.png\",\"contentUrl\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/specialty-care-logo-large-square.png\",\"width\":400,\"height\":400,\"caption\":\"Ameripharma Specialty Care\"},\"image\":{\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/ameripharma\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/#\\\/schema\\\/person\\\/fa3e6923d70031df69b97d6c635ff5c8\",\"name\":\"Dr. Stephanie Shieh, PharmD\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"vi\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g\",\"caption\":\"Dr. Stephanie Shieh, PharmD\"},\"description\":\"Dr. Stephanie Shieh, PharmD was born in Kentucky and raised in Southern Los Angeles. She attended the Western University of Health Sciences and has been a practicing pharmacist for 7 years. The most rewarding part of her job is seeing her patients happy - whether it\u2019s helping them understand their medication, catching a drug interaction, or being able to communicate with their doctor to improve their therapy. She is currently precepting students from Marshall B. Ketchum University. In her free time, she enjoys spending quality time with her husband and 2 daughters. They love playing outside, doing arts and crafts, and having family dinner.\",\"url\":\"https:\\\/\\\/ameripharmaspecialty.com\\\/vi\\\/author\\\/stephanie-shieh\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"B\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed - Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t AmeriPharma\u00ae","description":"T\u00ecm hi\u1ec3u nguy\u00ean nh\u00e2n, tri\u1ec7u ch\u1ee9ng v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u1ed1t nh\u1ea5t cho b\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed. Nh\u1eadn h\u1ed7 tr\u1ee3 v\u00e0 th\u00f4ng tin c\u1ea7n thi\u1ebft \u0111\u1ec3 ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng b\u1ec7nh hi\u1ec7u qu\u1ea3 h\u01a1n.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/","og_locale":"vi_VN","og_type":"article","og_title":"Necrotizing Myopathy - AmeriPharma\u00ae Specialty Care","og_description":"Explore the causes, symptoms, and best treatments for necrotizing myopathy. Get the support and information you need to manage your condition more effectively.","og_url":"https:\/\/ameripharmaspecialty.com\/vi\/other-health-conditions\/necrotizing-myopathy\/","og_site_name":"AmeriPharma\u00ae Specialty Care","article_publisher":"https:\/\/www.facebook.com\/ameripharma\/","article_published_time":"2022-05-05T16:59:55+00:00","article_modified_time":"2026-03-26T21:07:07+00:00","og_image":[{"width":1280,"height":853,"url":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg","type":"image\/jpeg"}],"author":"Dr. Stephanie Shieh, PharmD","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Dr. Stephanie Shieh, PharmD","Est. reading time":"8 ph\u00fat"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#article","isPartOf":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/"},"author":{"name":"Dr. Stephanie Shieh, PharmD","@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/person\/fa3e6923d70031df69b97d6c635ff5c8"},"headline":"Necrotizing Myopathy","datePublished":"2022-05-05T16:59:55+00:00","dateModified":"2026-03-26T21:07:07+00:00","mainEntityOfPage":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/"},"wordCount":1598,"publisher":{"@id":"https:\/\/ameripharmaspecialty.com\/#organization"},"image":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#primaryimage"},"thumbnailUrl":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg","keywords":["Dr. Stephanie Shieh"],"articleSection":["HIV","Other Health Conditions"],"inLanguage":"vi"},{"@type":"WebPage","@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/","url":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/","name":"B\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed - Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t AmeriPharma\u00ae","isPartOf":{"@id":"https:\/\/ameripharmaspecialty.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#primaryimage"},"image":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#primaryimage"},"thumbnailUrl":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg","datePublished":"2022-05-05T16:59:55+00:00","dateModified":"2026-03-26T21:07:07+00:00","description":"T\u00ecm hi\u1ec3u nguy\u00ean nh\u00e2n, tri\u1ec7u ch\u1ee9ng v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u1ed1t nh\u1ea5t cho b\u1ec7nh c\u01a1 ho\u1ea1i t\u1eed. Nh\u1eadn h\u1ed7 tr\u1ee3 v\u00e0 th\u00f4ng tin c\u1ea7n thi\u1ebft \u0111\u1ec3 ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng b\u1ec7nh hi\u1ec7u qu\u1ea3 h\u01a1n.","breadcrumb":{"@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#breadcrumb"},"inLanguage":"vi","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/"]}]},{"@type":"ImageObject","inLanguage":"vi","@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#primaryimage","url":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg","contentUrl":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg","width":1280,"height":853,"caption":"Close-up of a patient\u2019s leg with visible muscle inflammation, representing necrotizing myopathy."},{"@type":"BreadcrumbList","@id":"https:\/\/ameripharmaspecialty.com\/other-health-conditions\/necrotizing-myopathy\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ameripharmaspecialty.com\/es\/"},{"@type":"ListItem","position":2,"name":"Necrotizing Myopathy"}]},{"@type":"WebSite","@id":"https:\/\/ameripharmaspecialty.com\/#website","url":"https:\/\/ameripharmaspecialty.com\/","name":"Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t AmeriPharma\u00ae","description":"Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t c\u1ee7a AmeriPharma","publisher":{"@id":"https:\/\/ameripharmaspecialty.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ameripharmaspecialty.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"vi"},{"@type":"Organization","@id":"https:\/\/ameripharmaspecialty.com\/#organization","name":"Ch\u0103m s\u00f3c \u0111\u1eb7c bi\u1ec7t Ameripharma","url":"https:\/\/ameripharmaspecialty.com\/","logo":{"@type":"ImageObject","inLanguage":"vi","@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/logo\/image\/","url":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/specialty-care-logo-large-square.png","contentUrl":"https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2024\/07\/specialty-care-logo-large-square.png","width":400,"height":400,"caption":"Ameripharma Specialty Care"},"image":{"@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ameripharma\/"]},{"@type":"Person","@id":"https:\/\/ameripharmaspecialty.com\/#\/schema\/person\/fa3e6923d70031df69b97d6c635ff5c8","name":"Ti\u1ebfn s\u0129 Stephanie Shieh, Ti\u1ebfn s\u0129 D\u01b0\u1ee3c","image":{"@type":"ImageObject","inLanguage":"vi","@id":"https:\/\/secure.gravatar.com\/avatar\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/17407fcaa2338528a97840a39d751fc8d0c3680456bf6472a12061869c935718?s=96&d=mm&r=g","caption":"Dr. Stephanie Shieh, PharmD"},"description":"Ti\u1ebfn s\u0129 Stephanie Shieh, PharmD sinh ra t\u1ea1i Kentucky v\u00e0 l\u1edbn l\u00ean \u1edf Nam Los Angeles. C\u00f4 theo h\u1ecdc t\u1ea1i \u0110\u1ea1i h\u1ecdc Khoa h\u1ecdc S\u1ee9c kh\u1ecfe Western v\u00e0 \u0111\u00e3 h\u00e0nh ngh\u1ec1 d\u01b0\u1ee3c s\u0129 trong 7 n\u0103m. Ph\u1ea7n b\u1ed5 \u00edch nh\u1ea5t trong c\u00f4ng vi\u1ec7c c\u1ee7a c\u00f4 l\u00e0 th\u1ea5y b\u1ec7nh nh\u00e2n c\u1ee7a m\u00ecnh h\u1ea1nh ph\u00fac - d\u00f9 l\u00e0 gi\u00fap h\u1ecd hi\u1ec3u v\u1ec1 thu\u1ed1c, ph\u00e1t hi\u1ec7n t\u01b0\u01a1ng t\u00e1c thu\u1ed1c hay c\u00f3 th\u1ec3 giao ti\u1ebfp v\u1edbi b\u00e1c s\u0129 \u0111\u1ec3 c\u1ea3i thi\u1ec7n li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u1ee7a h\u1ecd. C\u00f4 hi\u1ec7n \u0111ang h\u01b0\u1edbng d\u1eabn sinh vi\u00ean t\u1ea1i \u0110\u1ea1i h\u1ecdc Marshall B. Ketchum. Trong th\u1eddi gian r\u1ea3nh r\u1ed7i, c\u00f4 th\u00edch d\u00e0nh th\u1eddi gian ch\u1ea5t l\u01b0\u1ee3ng cho ch\u1ed3ng v\u00e0 2 con g\u00e1i. H\u1ecd th\u00edch ch\u01a1i ngo\u00e0i tr\u1eddi, l\u00e0m \u0111\u1ed3 th\u1ee7 c\u00f4ng m\u1ef9 ngh\u1ec7 v\u00e0 \u0103n t\u1ed1i c\u00f9ng gia \u0111\u00ecnh.","url":"https:\/\/ameripharmaspecialty.com\/vi\/author\/stephanie-shieh\/"}]}},"uagb_featured_image_src":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-150x150.jpeg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-300x200.jpeg",300,200,true],"medium_large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-768x512.jpeg",768,512,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-1024x682.jpeg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",600,400,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-330x220.jpeg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-1146x380.jpeg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-86x57.jpeg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-167x111.jpeg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-280x187.jpeg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-370x247.jpeg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-960x640.jpeg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false]},"uagb_author_info":{"display_name":"Dr. Stephanie Shieh, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/stephanie-shieh\/"},"uagb_comment_info":2,"uagb_excerpt":"The term \u201cmyopathy\u201d generally means muscle weakness, while the term \u201cnecrotizing\u201d means cell death and necrosis. Necrotizing myopathy, also known as necrotizing autoimmune myopathy (NAM) or immune-mediated necrotizing myopathy (IMNM), is characterized by cell death and necrosis of muscle cells, particularly the muscles closer to the center of the body.","rttpg_featured_image_url":{"full":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"landscape":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"portraits":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"thumbnail":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-150x150.jpeg",150,150,true],"medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-300x200.jpeg",300,200,true],"large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-1024x682.jpeg",1024,682,true],"1536x1536":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"2048x2048":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false],"trp-custom-language-flag":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",18,12,false],"block-image-html-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",600,400,false],"ct-gallery":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-330x220.jpeg",330,220,true],"ct-section-header":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-1146x380.jpeg",1146,380,true],"ct-thumb":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-86x57.jpeg",86,57,true],"ct-thumb-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-167x111.jpeg",167,111,true],"ct-small":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-280x187.jpeg",280,187,true],"ct-medium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-370x247.jpeg",370,247,true],"ct-xmedium":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy-960x640.jpeg",960,640,true],"ct-large":["https:\/\/ameripharmaspecialty.com\/wp-content\/uploads\/2022\/05\/necrotizing-myopathy.jpeg",1280,853,false]},"rttpg_author":{"display_name":"Dr. Stephanie Shieh, PharmD","author_link":"https:\/\/ameripharmaspecialty.com\/vi\/author\/stephanie-shieh\/"},"rttpg_comment":2,"rttpg_category":"<a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/hiv\/\" rel=\"category tag\">HIV<\/a> <a href=\"https:\/\/ameripharmaspecialty.com\/vi\/category\/other-health-conditions\/\" rel=\"category tag\">Other Health Conditions<\/a>","rttpg_excerpt":"The term \u201cmyopathy\u201d generally means muscle weakness, while the term \u201cnecrotizing\u201d means cell death and necrosis. Necrotizing myopathy, also known as necrotizing autoimmune myopathy (NAM) or immune-mediated necrotizing myopathy (IMNM), is characterized by cell death and necrosis of muscle cells, particularly the muscles closer to the center of the body.","_links":{"self":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/20067","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/comments?post=20067"}],"version-history":[{"count":0,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/posts\/20067\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media\/20068"}],"wp:attachment":[{"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/media?parent=20067"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/categories?post=20067"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ameripharmaspecialty.com\/vi\/wp-json\/wp\/v2\/tags?post=20067"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}